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The map label for this gene is fruR [H]

Identifier: 57651538

GI number: 57651538

Start: 778780

End: 779544

Strand: Direct

Name: fruR [H]

Synonym: SACOL0757

Alternate gene names: 57651538

Gene position: 778780-779544 (Clockwise)

Preceding gene: 57651537

Following gene: 57651539

Centisome position: 27.72

GC content: 31.76

Gene sequence:

>765_bases
ATGATGATAATTACTGAAAAAAGACACGAGTTAATATTAGAAGAACTTTTGCACAAAGATTTTTTGACTTTACAAGAATT
AATAGATCGAACTGGTTGCAGTGCTTCAACAATACGAAGAGATTTATCTAAACTACAACAATTAGGGAAATTGCAACGTG
TGCATGGTGGTGCAATGTTAAAAGAAAATCGTATGGTTGAGGCGAATTTAACTGAAAAATTAGCAACGAATCTTGATGAA
AAGAAAATGATTGCTAAAATAGCAGCTAATCAAATCAACGATAATGAATGCTTATTTATCGATGCTGGTTCATCTACATT
GGAGCTAATTAAATATATTCAAGCGAAAGATATCATTGTGGTAACCAATGGTTTAACACATGTAGAAGCTTTACTTAAAA
AAGGTATTAAAACAATTATGCTAGGTGGTCAAGTTAAAGAAAATACACTTGCTACGATTGGTTCTAGTGCTATGGAGATA
TTAAGACGATATTGTTTCGATAAAGCTTTTATCGGGATGAATGGATTAGATATTGAACTTGGATTAACTACTCCCGATGA
GCAAGAGGCATTAGTTAAACAAACAGCAATGTCATTAGCCAATCAATCATTTGTACTTATAGATCATTCTAAGTTTAATA
AAGTATATTTTGCTCGTGTACCTTTGCTAGAAAGTACGACAATCATCACATCTGAAAAAGCATTAAATCAAGAATCGTTA
AAAGAATACCAACAAAAGTATCACTTTATAGGAGGGACTTTATGA

Upstream 100 bases:

>100_bases
GTAATTTTATCGTCACAATTTGAGTGTTTGTGATTGTTTTTGGTAATTTATGATTGAAAAGTGAAAGCGTACTCATTATA
ATACAAAGTGAGATGGGGTG

Downstream 100 bases:

>100_bases
TTTATACAGTGACTTTCAATCCTTCAATTGACTATGTCATTTTTACGAATGATTTTAAAATTGATGGTTTGAACAGAGCA
ACAGCAACATATAAATTCGC

Product: DeoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MMIITEKRHELILEELLHKDFLTLQELIDRTGCSASTIRRDLSKLQQLGKLQRVHGGAMLKENRMVEANLTEKLATNLDE
KKMIAKIAANQINDNECLFIDAGSSTLELIKYIQAKDIIVVTNGLTHVEALLKKGIKTIMLGGQVKENTLATIGSSAMEI
LRRYCFDKAFIGMNGLDIELGLTTPDEQEALVKQTAMSLANQSFVLIDHSKFNKVYFARVPLLESTTIITSEKALNQESL
KEYQQKYHFIGGTL

Sequences:

>Translated_254_residues
MMIITEKRHELILEELLHKDFLTLQELIDRTGCSASTIRRDLSKLQQLGKLQRVHGGAMLKENRMVEANLTEKLATNLDE
KKMIAKIAANQINDNECLFIDAGSSTLELIKYIQAKDIIVVTNGLTHVEALLKKGIKTIMLGGQVKENTLATIGSSAMEI
LRRYCFDKAFIGMNGLDIELGLTTPDEQEALVKQTAMSLANQSFVLIDHSKFNKVYFARVPLLESTTIITSEKALNQESL
KEYQQKYHFIGGTL
>Mature_254_residues
MMIITEKRHELILEELLHKDFLTLQELIDRTGCSASTIRRDLSKLQQLGKLQRVHGGAMLKENRMVEANLTEKLATNLDE
KKMIAKIAANQINDNECLFIDAGSSTLELIKYIQAKDIIVVTNGLTHVEALLKKGIKTIMLGGQVKENTLATIGSSAMEI
LRRYCFDKAFIGMNGLDIELGLTTPDEQEALVKQTAMSLANQSFVLIDHSKFNKVYFARVPLLESTTIITSEKALNQESL
KEYQQKYHFIGGTL

Specific function: Unknown

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI226510968, Length=234, Percent_Identity=32.9059829059829, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1789519, Length=241, Percent_Identity=29.045643153527, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1788069, Length=206, Percent_Identity=32.0388349514563, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI1789829, Length=211, Percent_Identity=28.9099526066351, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1787540, Length=230, Percent_Identity=29.1304347826087, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI1790635, Length=243, Percent_Identity=30.8641975308642, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1789059, Length=244, Percent_Identity=28.6885245901639, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI1787063, Length=242, Percent_Identity=30.1652892561983, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1790753, Length=237, Percent_Identity=25.7383966244726, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI87082344, Length=209, Percent_Identity=25.3588516746411, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1789170, Length=229, Percent_Identity=29.2576419213974, Blast_Score=73, Evalue=2e-14,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 28500; Mature: 28500

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMIITEKRHELILEELLHKDFLTLQELIDRTGCSASTIRRDLSKLQQLGKLQRVHGGAML
CEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCEE
KENRMVEANLTEKLATNLDEKKMIAKIAANQINDNECLFIDAGSSTLELIKYIQAKDIIV
CCCCEEEHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHCCEEE
VTNGLTHVEALLKKGIKTIMLGGQVKENTLATIGSSAMEILRRYCFDKAFIGMNGLDIEL
EECCHHHHHHHHHCCHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
GLTTPDEQEALVKQTAMSLANQSFVLIDHSKFNKVYFARVPLLESTTIITSEKALNQESL
ECCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEEECCCCCCCEEEECHHHCCHHHH
KEYQQKYHFIGGTL
HHHHHHHHHCCCCC
>Mature Secondary Structure
MMIITEKRHELILEELLHKDFLTLQELIDRTGCSASTIRRDLSKLQQLGKLQRVHGGAML
CEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCEE
KENRMVEANLTEKLATNLDEKKMIAKIAANQINDNECLFIDAGSSTLELIKYIQAKDIIV
CCCCEEEHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHCCEEE
VTNGLTHVEALLKKGIKTIMLGGQVKENTLATIGSSAMEILRRYCFDKAFIGMNGLDIEL
EECCHHHHHHHHHCCHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
GLTTPDEQEALVKQTAMSLANQSFVLIDHSKFNKVYFARVPLLESTTIITSEKALNQESL
ECCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEEECCCCCCCEEEECHHHCCHHHH
KEYQQKYHFIGGTL
HHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]