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The map label for this gene is ykuM [H]

Identifier: 57651513

GI number: 57651513

Start: 755578

End: 756444

Strand: Direct

Name: ykuM [H]

Synonym: SACOL0731

Alternate gene names: 57651513

Gene position: 755578-756444 (Clockwise)

Preceding gene: 57651512

Following gene: 57651514

Centisome position: 26.89

GC content: 32.06

Gene sequence:

>867_bases
ATGAAGATTGAAGACTATCGTTTACTAATAACATTAGACGAAACGAAAACGTTACGTAAAGCGGCTGAAATTTTATATAT
ATCTCAACCTGCTGTTACACAAAGACTAAAAGCTATTGAAAATGCTTTTGGAGTAGATATTTTTATCAGAACAAAAAAAC
AATTGATTACAACAACTGAAGGAACAATGATTATTGAGCATGCTCGTGACATGTTGAAAAGAGAGCGATTATTTTTTGAC
AAAATGCAGGCACATATTGGTGAAGTGAATGGAACAATATCAATCGGGTGTTCTTCTTTGATTGGACAAACCTTACTTCC
TGAAGTTTTGAGCCTATATAATGCCCAATTTCCTAATGTTGAAATACAAGTGCAAGTTGGTTCAACTGAACAAATTAAAG
CAAATCATAGAGATTATCATGTTATGATAACTCGTGGAAATAAGGTAATGAATTTAGCTAACACACATTTATTTAATGAT
GATCATTATTTTATTTTTCCAAAAAATAGACGAGATGATGTTACAAAGTTACCATTTATAGAGTTTCAAGCTGATCCGAT
TTATATAAATCAAATAAAAGAATGGTATAACGATAATTTAGAACAAGATTACCATGCAACTATTACAGTGGATCAAGTAG
CAACTTGCAAAGAAATGTTGATTAGTGGTGTAGGTGTTACAATCTTGCCAGAAATTATGATGAAAAATATCAGCAAAGAA
CAATTTGAGTTTGAAAAAGTAGAAATTGATAATGAACCGCTGATTCGTTCGACATTTATGAGTTATGATCCGAGCATGTT
GCAATTGCCACAAGTTGATTCTTTTGTAAATCTCATGGCGAGCTTTGTTGAACAACCAAAGGCGTAG

Upstream 100 bases:

>100_bases
GCCATACCAATAAAATTGGTGAAATTATTCGTTAGTAATGAACTCATGAATGCTTGTAGCCATGAAAGTTCAATAATTGA
ATAATTTATGGGGGGAAATT

Downstream 100 bases:

>100_bases
TTTTAGACTAATTTAAGGTTTGTATTTAATTTTAAACTATTCGGTTAAATTGAACGTAGTTGGTTGCTAATGCACCAACA
GCAAAAGAGCCCCTAATTAA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 288; Mature: 288

Protein sequence:

>288_residues
MKIEDYRLLITLDETKTLRKAAEILYISQPAVTQRLKAIENAFGVDIFIRTKKQLITTTEGTMIIEHARDMLKRERLFFD
KMQAHIGEVNGTISIGCSSLIGQTLLPEVLSLYNAQFPNVEIQVQVGSTEQIKANHRDYHVMITRGNKVMNLANTHLFND
DHYFIFPKNRRDDVTKLPFIEFQADPIYINQIKEWYNDNLEQDYHATITVDQVATCKEMLISGVGVTILPEIMMKNISKE
QFEFEKVEIDNEPLIRSTFMSYDPSMLQLPQVDSFVNLMASFVEQPKA

Sequences:

>Translated_288_residues
MKIEDYRLLITLDETKTLRKAAEILYISQPAVTQRLKAIENAFGVDIFIRTKKQLITTTEGTMIIEHARDMLKRERLFFD
KMQAHIGEVNGTISIGCSSLIGQTLLPEVLSLYNAQFPNVEIQVQVGSTEQIKANHRDYHVMITRGNKVMNLANTHLFND
DHYFIFPKNRRDDVTKLPFIEFQADPIYINQIKEWYNDNLEQDYHATITVDQVATCKEMLISGVGVTILPEIMMKNISKE
QFEFEKVEIDNEPLIRSTFMSYDPSMLQLPQVDSFVNLMASFVEQPKA
>Mature_288_residues
MKIEDYRLLITLDETKTLRKAAEILYISQPAVTQRLKAIENAFGVDIFIRTKKQLITTTEGTMIIEHARDMLKRERLFFD
KMQAHIGEVNGTISIGCSSLIGQTLLPEVLSLYNAQFPNVEIQVQVGSTEQIKANHRDYHVMITRGNKVMNLANTHLFND
DHYFIFPKNRRDDVTKLPFIEFQADPIYINQIKEWYNDNLEQDYHATITVDQVATCKEMLISGVGVTILPEIMMKNISKE
QFEFEKVEIDNEPLIRSTFMSYDPSMLQLPQVDSFVNLMASFVEQPKA

Specific function: Hydrogen Peroxide Sensor. Activates The Expression Of A Regulon Of Hydrogen Peroxide-Inducible Genes Such As Katg, Gor, Ahpc, Ahpf, Oxys (A Regulatory RNA), Dps, Fur And Grxa. Oxyr Expression Is Negatively Autoregulated By Binding To A 43 Bp Region Upstre

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=136, Percent_Identity=29.4117647058824, Blast_Score=77, Evalue=9e-16,
Organism=Escherichia coli, GI1787601, Length=127, Percent_Identity=26.7716535433071, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI145693105, Length=260, Percent_Identity=23.0769230769231, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1790208, Length=250, Percent_Identity=21.2, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1788297, Length=261, Percent_Identity=22.2222222222222, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1788481, Length=128, Percent_Identity=31.25, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33245; Mature: 33245

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIEDYRLLITLDETKTLRKAAEILYISQPAVTQRLKAIENAFGVDIFIRTKKQLITTTE
CCCCCEEEEEEECCHHHHHHHHHEEEECCHHHHHHHHHHHHHCCEEEEEECCHHEEEECC
GTMIIEHARDMLKRERLFFDKMQAHIGEVNGTISIGCSSLIGQTLLPEVLSLYNAQFPNV
CCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHHHHCCCCCCE
EIQVQVGSTEQIKANHRDYHVMITRGNKVMNLANTHLFNDDHYFIFPKNRRDDVTKLPFI
EEEEEECCCHHEECCCCCEEEEEECCCEEEEEHHHEEECCCEEEEECCCCCCCCCCCCEE
EFQADPIYINQIKEWYNDNLEQDYHATITVDQVATCKEMLISGVGVTILPEIMMKNISKE
EEECCCEEHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHH
QFEFEKVEIDNEPLIRSTFMSYDPSMLQLPQVDSFVNLMASFVEQPKA
HHEEEEEECCCCCHHHHHHHCCCCCCEECCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKIEDYRLLITLDETKTLRKAAEILYISQPAVTQRLKAIENAFGVDIFIRTKKQLITTTE
CCCCCEEEEEEECCHHHHHHHHHEEEECCHHHHHHHHHHHHHCCEEEEEECCHHEEEECC
GTMIIEHARDMLKRERLFFDKMQAHIGEVNGTISIGCSSLIGQTLLPEVLSLYNAQFPNV
CCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHHHHCCCCCCE
EIQVQVGSTEQIKANHRDYHVMITRGNKVMNLANTHLFNDDHYFIFPKNRRDDVTKLPFI
EEEEEECCCHHEECCCCCEEEEEECCCEEEEEHHHEEECCCEEEEECCCCCCCCCCCCEE
EFQADPIYINQIKEWYNDNLEQDYHATITVDQVATCKEMLISGVGVTILPEIMMKNISKE
EEECCCEEHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHH
QFEFEKVEIDNEPLIRSTFMSYDPSMLQLPQVDSFVNLMASFVEQPKA
HHEEEEEECCCCCHHHHHHHCCCCCCEECCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]