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The map label for this gene is melR [C]

Identifier: 57651508

GI number: 57651508

Start: 750431

End: 752581

Strand: Direct

Name: melR [C]

Synonym: SACOL0725

Alternate gene names: 57651508

Gene position: 750431-752581 (Clockwise)

Preceding gene: 57651507

Following gene: 57651509

Centisome position: 26.71

GC content: 26.87

Gene sequence:

>2151_bases
ATGGCAAAATCATGCTTGCATATACTTACTAATAATGAATATGCGACAACGCGTTGCCAAGATGGCATAGTCTTATTTTG
GCCAATTGACGGGGAAATCGAACTACAAAAATTTCGTAAAAGTAAAATAATTGAAGATGATATATATATTATTAATCATC
TGGATGTATTTAGTATTAAGAATAATAAAAAAACGATCATGTTGTATTTGAGTAGCGATTGGTTTGCGGAATTAGGCTTT
ACTTTCTTTAATTACCACTATACAGCAAAGTTGATTAAATCATCCTATAATTTGAAATGTCTACTATTAAAATTGACATA
TCGATACCTTGATAATCAGCCTCTTAATGACGCTGATATTAGAAAATTACAGGATATTATTAAAATCATTGCAAAAGAAG
CAAGTATGGATAAAAAGATTGCACAAAATCAATATCGATATGCGTATTATGGTGATTTGCGTGATGAGCTCGAATATATT
TATCAAAATGTAAATCAACGATTGACATTAAAAAGTGTCGCTGATAAATTATTTGTCTCAAAGTCAAATTTGTCATCACA
ATTCCACTTACTTATGGGCATGGGTTTTAAAAAATATATTGATACTTTGAAAATTGGTAAATCGATTGAAATTCTACTTA
CTACTGATAGTACTATTAGCAACATAAGTGAACATTTAGGTTTTAGTAGTAGCTCCACTTACTCTAAAATGTTTAAAAGT
TATATGGATATAACACCGAATGAATATCGTAATTTATCAAAATATAATAAATGTTTAATGCTAAAGCCAGAACCACTAGT
AGGCAAAATGGTGCAAGAAGTAAAAGAAATCATATTGAATTATATTGAACATTATAAAAACCACCTAACTGATGTTATAC
ATATTGATGAAGACAAATTTGAAACACCTAAATTGTTTCAAACGGTTATTCAAATAAATACTTATACAGAAATGAAATTA
GTTTTCTTAGAAGGAATCTTTAAAACCTTATTGAATAAGAACAGTCAAGTTGTCTTTTTCATCATGCCATCGATTCTAAA
AAGTAAAAATACCATGTCCGAAGAAGAAAAATTCACAATCATTAAAACAATAATTGAAAGTGATCTAAAGATAGCATTTA
ATATAAATAATATTGAAACAACTTATTTTGTTGAAGAAGCTTTTATGAGTGTTTTCAGACAAATATCTCCAAACGAATTA
AGTAATCATAATAATTACGAAGTGCATTTTGTTTTTGATTTATCATTGATGGAAATTAGAACAATTTATCGAATGATATT
AAAATTACATAACATCATGTTGAATGTGAAATTAGGATTGAACATTACCTGTTTATTTGAAAAACCTTCAGTTTTTAAAT
CACTAGTATCACAAATAAAGCGACTTAAATTCGATTCGTTAATAATAGATAATGCAAATTTAAGTAGCCCTTATTTGATG
GGGGAAAGTGATGAGTTACTATTGAAAAATATTTTGCATTTTAAAAATTTAAAACAAGTAATTAATGAATTGGATATTGA
ACAAGAAAAGCTGATTTTTCTAAATGTTGAAAATCATAAACTGCTTAATAATAAAGAACGAGATCTAAGTAATAGTGCTC
CATTAATTTATAAGACATTAAGTGCGCTGTATCACAACTTTGATGGCTTTGGATTAAACATTTTTGACAATCATCAAGCA
TTTAATGCGATGCATCTATATGACAAAAATGGATTTAAAACAACACTAGGTCTTATATTAGAAAAGTTTATCGAATATGT
CTCGAAACCAAAATACGAAAACAGTTATTATTCTATTTTTGATATAGAGAATTATTATTGTCTTGTTATTTATGATTGGC
GAGTGATAGAGAGCGAGACAATTATGAGTAATTTTGAGGATAGTCAAGTTTATATAAATTTTAAAAACAATGTTTTAAAC
GATAAATATCTAATTGTAATAGAAACATTGGACGAAAATAGTGGCAACATTAATCATTTGATTTCTAAAGAATTAAGAGA
TAAATATGAATGGAACCCTAGTTTACTATCTAAAATTGACAACTACCTTAAACCAGCAATAGAGATTAAAGAGCATAATT
TTAGTGATAATTCCTTGAATATTAACGTTACTTTTAATGCGTTATACATAATTAAAATAGGAAAAAAATAA

Upstream 100 bases:

>100_bases
ATTTGGTATTCGTATTGTGTTAAATTTACGTTTAATTAAATAAGTTAAATATTATAGGGAATGATAAAAGTGGTACTTAA
ATATAGAAAGAGGTAAAGTT

Downstream 100 bases:

>100_bases
CACCTTGATATGTATTGCAAAATTTAATTTGCATTTGTTGGTAATTTTGACAACGTATTAAAAACAAATGAGAAAGACAA
TGGCTGAAAAATTTAAGATA

Product: AraC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 716; Mature: 715

Protein sequence:

>716_residues
MAKSCLHILTNNEYATTRCQDGIVLFWPIDGEIELQKFRKSKIIEDDIYIINHLDVFSIKNNKKTIMLYLSSDWFAELGF
TFFNYHYTAKLIKSSYNLKCLLLKLTYRYLDNQPLNDADIRKLQDIIKIIAKEASMDKKIAQNQYRYAYYGDLRDELEYI
YQNVNQRLTLKSVADKLFVSKSNLSSQFHLLMGMGFKKYIDTLKIGKSIEILLTTDSTISNISEHLGFSSSSTYSKMFKS
YMDITPNEYRNLSKYNKCLMLKPEPLVGKMVQEVKEIILNYIEHYKNHLTDVIHIDEDKFETPKLFQTVIQINTYTEMKL
VFLEGIFKTLLNKNSQVVFFIMPSILKSKNTMSEEEKFTIIKTIIESDLKIAFNINNIETTYFVEEAFMSVFRQISPNEL
SNHNNYEVHFVFDLSLMEIRTIYRMILKLHNIMLNVKLGLNITCLFEKPSVFKSLVSQIKRLKFDSLIIDNANLSSPYLM
GESDELLLKNILHFKNLKQVINELDIEQEKLIFLNVENHKLLNNKERDLSNSAPLIYKTLSALYHNFDGFGLNIFDNHQA
FNAMHLYDKNGFKTTLGLILEKFIEYVSKPKYENSYYSIFDIENYYCLVIYDWRVIESETIMSNFEDSQVYINFKNNVLN
DKYLIVIETLDENSGNINHLISKELRDKYEWNPSLLSKIDNYLKPAIEIKEHNFSDNSLNINVTFNALYIIKIGKK

Sequences:

>Translated_716_residues
MAKSCLHILTNNEYATTRCQDGIVLFWPIDGEIELQKFRKSKIIEDDIYIINHLDVFSIKNNKKTIMLYLSSDWFAELGF
TFFNYHYTAKLIKSSYNLKCLLLKLTYRYLDNQPLNDADIRKLQDIIKIIAKEASMDKKIAQNQYRYAYYGDLRDELEYI
YQNVNQRLTLKSVADKLFVSKSNLSSQFHLLMGMGFKKYIDTLKIGKSIEILLTTDSTISNISEHLGFSSSSTYSKMFKS
YMDITPNEYRNLSKYNKCLMLKPEPLVGKMVQEVKEIILNYIEHYKNHLTDVIHIDEDKFETPKLFQTVIQINTYTEMKL
VFLEGIFKTLLNKNSQVVFFIMPSILKSKNTMSEEEKFTIIKTIIESDLKIAFNINNIETTYFVEEAFMSVFRQISPNEL
SNHNNYEVHFVFDLSLMEIRTIYRMILKLHNIMLNVKLGLNITCLFEKPSVFKSLVSQIKRLKFDSLIIDNANLSSPYLM
GESDELLLKNILHFKNLKQVINELDIEQEKLIFLNVENHKLLNNKERDLSNSAPLIYKTLSALYHNFDGFGLNIFDNHQA
FNAMHLYDKNGFKTTLGLILEKFIEYVSKPKYENSYYSIFDIENYYCLVIYDWRVIESETIMSNFEDSQVYINFKNNVLN
DKYLIVIETLDENSGNINHLISKELRDKYEWNPSLLSKIDNYLKPAIEIKEHNFSDNSLNINVTFNALYIIKIGKK
>Mature_715_residues
AKSCLHILTNNEYATTRCQDGIVLFWPIDGEIELQKFRKSKIIEDDIYIINHLDVFSIKNNKKTIMLYLSSDWFAELGFT
FFNYHYTAKLIKSSYNLKCLLLKLTYRYLDNQPLNDADIRKLQDIIKIIAKEASMDKKIAQNQYRYAYYGDLRDELEYIY
QNVNQRLTLKSVADKLFVSKSNLSSQFHLLMGMGFKKYIDTLKIGKSIEILLTTDSTISNISEHLGFSSSSTYSKMFKSY
MDITPNEYRNLSKYNKCLMLKPEPLVGKMVQEVKEIILNYIEHYKNHLTDVIHIDEDKFETPKLFQTVIQINTYTEMKLV
FLEGIFKTLLNKNSQVVFFIMPSILKSKNTMSEEEKFTIIKTIIESDLKIAFNINNIETTYFVEEAFMSVFRQISPNELS
NHNNYEVHFVFDLSLMEIRTIYRMILKLHNIMLNVKLGLNITCLFEKPSVFKSLVSQIKRLKFDSLIIDNANLSSPYLMG
ESDELLLKNILHFKNLKQVINELDIEQEKLIFLNVENHKLLNNKERDLSNSAPLIYKTLSALYHNFDGFGLNIFDNHQAF
NAMHLYDKNGFKTTLGLILEKFIEYVSKPKYENSYYSIFDIENYYCLVIYDWRVIESETIMSNFEDSQVYINFKNNVLND
KYLIVIETLDENSGNINHLISKELRDKYEWNPSLLSKIDNYLKPAIEIKEHNFSDNSLNINVTFNALYIIKIGKK

Specific function: Transcription Activator For The Expression Of The Melab Operon. Melr Binds At Two Sites Located Upstream Of The Melab Transcription Site. [C]

COG id: COG2207

COG function: function code K; AraC-type DNA-binding domain-containing proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 HTH araC/xylS-type DNA-binding domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017853
- InterPro:   IPR013781
- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR003313
- InterPro:   IPR020449
- InterPro:   IPR018060 [H]

Pfam domain/function: PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 84118; Mature: 83987

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: PS00041 HTH_ARAC_FAMILY_1 ; PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKSCLHILTNNEYATTRCQDGIVLFWPIDGEIELQKFRKSKIIEDDIYIINHLDVFSIK
CCCCEEEEEECCCEEEEECCCCEEEEEECCCCCHHHHHHHHCCCCCCEEEEEEEEEEEEE
NNKKTIMLYLSSDWFAELGFTFFNYHYTAKLIKSSYNLKCLLLKLTYRYLDNQPLNDADI
CCCEEEEEEECCCHHHHHCHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHCCCCCCHHHH
RKLQDIIKIIAKEASMDKKIAQNQYRYAYYGDLRDELEYIYQNVNQRLTLKSVADKLFVS
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHCCEEEHHHHHHHHHEE
KSNLSSQFHLLMGMGFKKYIDTLKIGKSIEILLTTDSTISNISEHLGFSSSSTYSKMFKS
CCCCCHHHHHHHCCCHHHHHHHHHCCCCEEEEEECCCHHHHHHHHCCCCCCCHHHHHHHH
YMDITPNEYRNLSKYNKCLMLKPEPLVGKMVQEVKEIILNYIEHYKNHLTDVIHIDEDKF
HHCCCCHHHHCHHHHCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCC
ETPKLFQTVIQINTYTEMKLVFLEGIFKTLLNKNSQVVFFIMPSILKSKNTMSEEEKFTI
CCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECHHHCCCCCCCCHHHHHH
IKTIIESDLKIAFNINNIETTYFVEEAFMSVFRQISPNELSNHNNYEVHFVFDLSLMEIR
HHHHHHCCCEEEEEECCCEEHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECHHHHHH
TIYRMILKLHNIMLNVKLGLNITCLFEKPSVFKSLVSQIKRLKFDSLIIDNANLSSPYLM
HHHHHHHHHHHEEEEEEECCEEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCCCCCEEE
GESDELLLKNILHFKNLKQVINELDIEQEKLIFLNVENHKLLNNKERDLSNSAPLIYKTL
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHH
SALYHNFDGFGLNIFDNHQAFNAMHLYDKNGFKTTLGLILEKFIEYVSKPKYENSYYSIF
HHHHHCCCCCEEEEECCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEE
DIENYYCLVIYDWRVIESETIMSNFEDSQVYINFKNNVLNDKYLIVIETLDENSGNINHL
EECCEEEEEEEEEEEECCHHHHCCCCCCEEEEEECCCCCCCEEEEEEEEECCCCCCHHHH
ISKELRDKYEWNPSLLSKIDNYLKPAIEIKEHNFSDNSLNINVTFNALYIIKIGKK
HHHHHHHHCCCCHHHHHHHHHHHCCCEEEECCCCCCCEEEEEEEEEEEEEEEECCC
>Mature Secondary Structure 
AKSCLHILTNNEYATTRCQDGIVLFWPIDGEIELQKFRKSKIIEDDIYIINHLDVFSIK
CCCEEEEEECCCEEEEECCCCEEEEEECCCCCHHHHHHHHCCCCCCEEEEEEEEEEEEE
NNKKTIMLYLSSDWFAELGFTFFNYHYTAKLIKSSYNLKCLLLKLTYRYLDNQPLNDADI
CCCEEEEEEECCCHHHHHCHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHCCCCCCHHHH
RKLQDIIKIIAKEASMDKKIAQNQYRYAYYGDLRDELEYIYQNVNQRLTLKSVADKLFVS
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHCCEEEHHHHHHHHHEE
KSNLSSQFHLLMGMGFKKYIDTLKIGKSIEILLTTDSTISNISEHLGFSSSSTYSKMFKS
CCCCCHHHHHHHCCCHHHHHHHHHCCCCEEEEEECCCHHHHHHHHCCCCCCCHHHHHHHH
YMDITPNEYRNLSKYNKCLMLKPEPLVGKMVQEVKEIILNYIEHYKNHLTDVIHIDEDKF
HHCCCCHHHHCHHHHCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCC
ETPKLFQTVIQINTYTEMKLVFLEGIFKTLLNKNSQVVFFIMPSILKSKNTMSEEEKFTI
CCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECHHHCCCCCCCCHHHHHH
IKTIIESDLKIAFNINNIETTYFVEEAFMSVFRQISPNELSNHNNYEVHFVFDLSLMEIR
HHHHHHCCCEEEEEECCCEEHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECHHHHHH
TIYRMILKLHNIMLNVKLGLNITCLFEKPSVFKSLVSQIKRLKFDSLIIDNANLSSPYLM
HHHHHHHHHHHEEEEEEECCEEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCCCCCEEE
GESDELLLKNILHFKNLKQVINELDIEQEKLIFLNVENHKLLNNKERDLSNSAPLIYKTL
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHH
SALYHNFDGFGLNIFDNHQAFNAMHLYDKNGFKTTLGLILEKFIEYVSKPKYENSYYSIF
HHHHHCCCCCEEEEECCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEE
DIENYYCLVIYDWRVIESETIMSNFEDSQVYINFKNNVLNDKYLIVIETLDENSGNINHL
EECCEEEEEEEEEEEECCHHHHCCCCCCEEEEEECCCCCCCEEEEEEEEECCCCCCHHHH
ISKELRDKYEWNPSLLSKIDNYLKPAIEIKEHNFSDNSLNINVTFNALYIIKIGKK
HHHHHHHHCCCCHHHHHHHHHHHCCCEEEECCCCCCCEEEEEEEEEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12044378 [H]