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The map label for this gene is yfnA [H]

Identifier: 57651459

GI number: 57651459

Start: 661423

End: 662907

Strand: Direct

Name: yfnA [H]

Synonym: SACOL0630

Alternate gene names: 57651459

Gene position: 661423-662907 (Clockwise)

Preceding gene: 57651458

Following gene: 57651463

Centisome position: 23.54

GC content: 35.62

Gene sequence:

>1485_bases
ATGGAAAAAAAGAATAAGCAAATAGATAGAGGCGATTTAAAACAAAACCTATCTGAAAAGTTTGTATGGGCGATTGCATA
TGGTTCATGTATCGGATGGGGCGCATTCATCATACCAGGAGACTGGATTAAGCAGTCAGGTCCGATTGCAGCATCAATTG
GTATAGTTATTGGTGCATTATTAATGATATTAATTGCGGTTAGTTATGGCGCATTAGTAGAGAGATTTCCAGTATCAGGG
GGCGCGTTTGCCTTTAGTTTCTTAAGTTTCGGCAGATATGTGAGTTTCTTCTCATCATGGTTTTTAACTTTTGGTTATGT
CTGTGTCGTTGCTTTAAATGCGACCGCATTCAGTTTACTAGTTAAATTCTTATTGCCAGATGTCTTAAATAATGGGAAAC
TATACACCATTGCGGGCTGGGACGTTTATATTACGGAAATCATTATTGCGACCGTATTACTACTTGTATTCATGCTAGTA
ACGATTCGTGGCGCAAGTGTATCTGGATCATTACAATATTATTTCTGTGTGGCGATGGTAATCGTCGTATTATTGATGTT
CTTTGGTTCATTCTTTGGTAATAATTTTGCACTTGAAAATTTACAACCGTTAGCTGAACCTAGCAAAGGATGGTTAGTGT
CTATTGTGGTTATTGTATCCGTGGCACCATGGGCATATGTTGGATTTGATAATATTCCACAAACAGCAGAAGAGTTTAAC
TTTGCACCAAACAAGACATTTAAGCTTATCGTGTACAGTTTATTAGCAGCATCATTAACTTATGTTGTCATGATTTTATA
CACTGGTTGGTTATCAACAAGTCATCAAAGTTTAAATGGGCAGTTGTGGTTAACAGGTGCTGTTACACAAACAGCATTTG
GTTATATTGGATTAGGTGTATTAGCAATTGCAATTATGATGGGTATATTTACTGGTTTAAATGGATTCTTGATGAGTTCA
AGTCGCTTGTTATTTTCTATGGGACGTTCAGGTATTATGCCAACAATGTTTAGTAAATTACATAGTAAATACAAAACACC
ATATGTCGCAATCATATTCCTAGTAGGAGTGTCGTTAATTGCACCTTGGCTAGGAAGAACTGCATTGACTTGGATTGTAG
ATATGTCATCTACTGGTGTATCCATTGCCTACTTTATTACATGTTTGTCTGCAGCGAAATTATTCAGTTATAACAAACAA
AGTAATACGTATGCACCGGTTTACAAAACGTTTGCTATTATCGGCTCATTTGTATCATTCATTTTCTTAGCGTTGTTATT
AGTGCCAGGTTCTCCTGCAGCACTGACTGCACCGTCTTATATTGCATTACTTGGATGGTTAATCATCGGTTTAATATTCT
TTGTGATTCGATATCCTAAATTGAAAAATATGGATAATGATGAATTAAGTCGCTTGATTTTAAATAGAAGTGAAAATGAA
GTTGATGATATGATTGAAGAACCTGAAAAAGAAAAAACTAAATAA

Upstream 100 bases:

>100_bases
CTATGTAACTAAACATTAAATTTTTAATAAAAATAATCAAGAAAAAGAGTTACAAACTCATCTTTTGGGTATAGAATACC
TTCGAGGTGAGTTTTTATTT

Downstream 100 bases:

>100_bases
TAAAAGAATCGCACAATAAACCTTCTTCATTCGGAGGCGTATCGTGCGATTTTTTGTATTATAAATTGACATTTAAGACG
AGGCAGCTGAACCTTATATA

Product: amino acid permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 494; Mature: 494

Protein sequence:

>494_residues
MEKKNKQIDRGDLKQNLSEKFVWAIAYGSCIGWGAFIIPGDWIKQSGPIAASIGIVIGALLMILIAVSYGALVERFPVSG
GAFAFSFLSFGRYVSFFSSWFLTFGYVCVVALNATAFSLLVKFLLPDVLNNGKLYTIAGWDVYITEIIIATVLLLVFMLV
TIRGASVSGSLQYYFCVAMVIVVLLMFFGSFFGNNFALENLQPLAEPSKGWLVSIVVIVSVAPWAYVGFDNIPQTAEEFN
FAPNKTFKLIVYSLLAASLTYVVMILYTGWLSTSHQSLNGQLWLTGAVTQTAFGYIGLGVLAIAIMMGIFTGLNGFLMSS
SRLLFSMGRSGIMPTMFSKLHSKYKTPYVAIIFLVGVSLIAPWLGRTALTWIVDMSSTGVSIAYFITCLSAAKLFSYNKQ
SNTYAPVYKTFAIIGSFVSFIFLALLLVPGSPAALTAPSYIALLGWLIIGLIFFVIRYPKLKNMDNDELSRLILNRSENE
VDDMIEEPEKEKTK

Sequences:

>Translated_494_residues
MEKKNKQIDRGDLKQNLSEKFVWAIAYGSCIGWGAFIIPGDWIKQSGPIAASIGIVIGALLMILIAVSYGALVERFPVSG
GAFAFSFLSFGRYVSFFSSWFLTFGYVCVVALNATAFSLLVKFLLPDVLNNGKLYTIAGWDVYITEIIIATVLLLVFMLV
TIRGASVSGSLQYYFCVAMVIVVLLMFFGSFFGNNFALENLQPLAEPSKGWLVSIVVIVSVAPWAYVGFDNIPQTAEEFN
FAPNKTFKLIVYSLLAASLTYVVMILYTGWLSTSHQSLNGQLWLTGAVTQTAFGYIGLGVLAIAIMMGIFTGLNGFLMSS
SRLLFSMGRSGIMPTMFSKLHSKYKTPYVAIIFLVGVSLIAPWLGRTALTWIVDMSSTGVSIAYFITCLSAAKLFSYNKQ
SNTYAPVYKTFAIIGSFVSFIFLALLLVPGSPAALTAPSYIALLGWLIIGLIFFVIRYPKLKNMDNDELSRLILNRSENE
VDDMIEEPEKEKTK
>Mature_494_residues
MEKKNKQIDRGDLKQNLSEKFVWAIAYGSCIGWGAFIIPGDWIKQSGPIAASIGIVIGALLMILIAVSYGALVERFPVSG
GAFAFSFLSFGRYVSFFSSWFLTFGYVCVVALNATAFSLLVKFLLPDVLNNGKLYTIAGWDVYITEIIIATVLLLVFMLV
TIRGASVSGSLQYYFCVAMVIVVLLMFFGSFFGNNFALENLQPLAEPSKGWLVSIVVIVSVAPWAYVGFDNIPQTAEEFN
FAPNKTFKLIVYSLLAASLTYVVMILYTGWLSTSHQSLNGQLWLTGAVTQTAFGYIGLGVLAIAIMMGIFTGLNGFLMSS
SRLLFSMGRSGIMPTMFSKLHSKYKTPYVAIIFLVGVSLIAPWLGRTALTWIVDMSSTGVSIAYFITCLSAAKLFSYNKQ
SNTYAPVYKTFAIIGSFVSFIFLALLLVPGSPAALTAPSYIALLGWLIIGLIFFVIRYPKLKNMDNDELSRLILNRSENE
VDDMIEEPEKEKTK

Specific function: Unknown

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI181337167, Length=397, Percent_Identity=23.6775818639798, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI87082250, Length=412, Percent_Identity=24.2718446601942, Blast_Score=66, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24666159, Length=400, Percent_Identity=24, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI221512776, Length=400, Percent_Identity=24, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24668806, Length=413, Percent_Identity=25.181598062954, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI21356285, Length=413, Percent_Identity=25.181598062954, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24668802, Length=413, Percent_Identity=25.181598062954, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR015606 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 54338; Mature: 54338

Theoretical pI: Translated: 9.06; Mature: 9.06

Prosite motif: PS01331 THYMIDYLATE_KINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHCCCCCCCCC
>Mature Secondary Structure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HHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9141694; 9384377 [H]