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The map label for this gene is cysS [H]

Identifier: 57651406

GI number: 57651406

Start: 598522

End: 599922

Strand: Direct

Name: cysS [H]

Synonym: SACOL0576

Alternate gene names: 57651406

Gene position: 598522-599922 (Clockwise)

Preceding gene: 57651405

Following gene: 57651407

Centisome position: 21.3

GC content: 33.05

Gene sequence:

>1401_bases
ATGATTACATTATATAATACGCTTACACGTCAAAAAGAAGTGTTCAAGCCTATAGAACCAGGGAAAGTAAAAATGTATGT
ATGTGGTCCTACTGTATATAACTACATTCATATTGGTAACGCAAGACCAGCAATTAATTATGACGTAGTGAGACGTTACT
TTGAATACCAAGGATATAATGTAGAATATGTATCAAATTTTACAGACGTAGATGATAAATTAATTAAACGTTCTCAAGAA
TTAAATCAGTCTGTTCCCGAAATTGCAGAAAAATATATCGCTGCTTTTCATGAAGATGTTGGTGCGTTAAATGTTAGAAA
AGCGACTTCAAATCCAAGGGTAATGGACCATATGGATGACATTATTCAATTTATTAAAGATTTGGTGGATCAAGGTTATG
CATATGAAAGTGGTGGCGATGTTTACTTTAGAACACGTAAATTTGAAGGTTATGGTAAATTAAGTCATCAATCCATAGAT
GACTTAAAAGTGGGTGCTCGTATAGATGCAGGAGAGCATAAAGAAGATGCACTTGATTTTACATTGTGGAAAAAAGCGAA
GCCTGGCGAGATTAGTTGGGATAGCCCATTTGGTGAAGGTAGACCAGGATGGCATATAGAATGTTCTGTAATGGCATTTC
ATGAGCTAGGACCTACAATTGATATACATGCGGGTGGTTCAGATTTACAATTTCCACATCATGAAAATGAAATAGCACAA
TCAGAAGCACATAATCATGCGCCATTTGCTAATTATTGGATGCATAATGGTTTCATTAATATTGATAATGAAAAAATGAG
TAAATCACTAGGCAACTTTATTTTAGTTCACGATATTATTAAAGAAGTTGATCCAGATGTACTAAGATTCTTTATGATTA
GCGTACATTATAGAAGCCCAATTAACTATAATCTAGAATTGGTAGAATCAGCACGTAGTGGACTAGAGCGTATTCGCAAT
AGTTATCAATTAATTGAAGAGCGCGCACAAATTGCTACTAATATTGAAAATCAACAGACATATATTGATCAAATTGATGC
GATTTTAAATCGTTTTGAAACAGTTATGAATGATGATTTTAATACAGCTAATGCAATTACAGCTTGGTATGATTTAGCAA
AACTTGCGAATAAATATGTACTAGAGAACACAACATCAACAGAAGTAATTGATAAATTTAAAGCAGTTTATCAAATTTTC
AGCGATGTTTTAGGTGTACCGTTAAAATCTAAAAATGCAGATGAATTATTGGATGAAGATGTTGAAAAATTAATCGAAGA
GCGTAATGAAGCAAGGAAAAACAAAGATTTTGCACGAGCAGATGAAATTCGAGACATGCTGAAATCACAAAACATTATAT
TAGAAGACACACCTCAAGGGGTTAGATTTAAACGTGGATAA

Upstream 100 bases:

>100_bases
GGAAAAACATTTGATCATCGCCATCTACCTGATCCAATTTATGAACAAATTAAGCATTTAGAACGACAACTTGAAAAGAC
TAGGAATGGAGAGATTCAAG

Downstream 100 bases:

>100_bases
TCAACAAGATAATCACATTAAATTATTGAATCCATTGACCTTAGCATATATGGGAGACGCAGTCTTAGATCAATATGTAC
GTACCTATATCGTTTTAAAG

Product: cysteinyl-tRNA synthetase

Products: NA

Alternate protein names: Cysteine--tRNA ligase; CysRS [H]

Number of amino acids: Translated: 466; Mature: 466

Protein sequence:

>466_residues
MITLYNTLTRQKEVFKPIEPGKVKMYVCGPTVYNYIHIGNARPAINYDVVRRYFEYQGYNVEYVSNFTDVDDKLIKRSQE
LNQSVPEIAEKYIAAFHEDVGALNVRKATSNPRVMDHMDDIIQFIKDLVDQGYAYESGGDVYFRTRKFEGYGKLSHQSID
DLKVGARIDAGEHKEDALDFTLWKKAKPGEISWDSPFGEGRPGWHIECSVMAFHELGPTIDIHAGGSDLQFPHHENEIAQ
SEAHNHAPFANYWMHNGFINIDNEKMSKSLGNFILVHDIIKEVDPDVLRFFMISVHYRSPINYNLELVESARSGLERIRN
SYQLIEERAQIATNIENQQTYIDQIDAILNRFETVMNDDFNTANAITAWYDLAKLANKYVLENTTSTEVIDKFKAVYQIF
SDVLGVPLKSKNADELLDEDVEKLIEERNEARKNKDFARADEIRDMLKSQNIILEDTPQGVRFKRG

Sequences:

>Translated_466_residues
MITLYNTLTRQKEVFKPIEPGKVKMYVCGPTVYNYIHIGNARPAINYDVVRRYFEYQGYNVEYVSNFTDVDDKLIKRSQE
LNQSVPEIAEKYIAAFHEDVGALNVRKATSNPRVMDHMDDIIQFIKDLVDQGYAYESGGDVYFRTRKFEGYGKLSHQSID
DLKVGARIDAGEHKEDALDFTLWKKAKPGEISWDSPFGEGRPGWHIECSVMAFHELGPTIDIHAGGSDLQFPHHENEIAQ
SEAHNHAPFANYWMHNGFINIDNEKMSKSLGNFILVHDIIKEVDPDVLRFFMISVHYRSPINYNLELVESARSGLERIRN
SYQLIEERAQIATNIENQQTYIDQIDAILNRFETVMNDDFNTANAITAWYDLAKLANKYVLENTTSTEVIDKFKAVYQIF
SDVLGVPLKSKNADELLDEDVEKLIEERNEARKNKDFARADEIRDMLKSQNIILEDTPQGVRFKRG
>Mature_466_residues
MITLYNTLTRQKEVFKPIEPGKVKMYVCGPTVYNYIHIGNARPAINYDVVRRYFEYQGYNVEYVSNFTDVDDKLIKRSQE
LNQSVPEIAEKYIAAFHEDVGALNVRKATSNPRVMDHMDDIIQFIKDLVDQGYAYESGGDVYFRTRKFEGYGKLSHQSID
DLKVGARIDAGEHKEDALDFTLWKKAKPGEISWDSPFGEGRPGWHIECSVMAFHELGPTIDIHAGGSDLQFPHHENEIAQ
SEAHNHAPFANYWMHNGFINIDNEKMSKSLGNFILVHDIIKEVDPDVLRFFMISVHYRSPINYNLELVESARSGLERIRN
SYQLIEERAQIATNIENQQTYIDQIDAILNRFETVMNDDFNTANAITAWYDLAKLANKYVLENTTSTEVIDKFKAVYQIF
SDVLGVPLKSKNADELLDEDVEKLIEERNEARKNKDFARADEIRDMLKSQNIILEDTPQGVRFKRG

Specific function: Unknown

COG id: COG0215

COG function: function code J; Cysteinyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI13375695, Length=482, Percent_Identity=34.4398340248963, Blast_Score=255, Evalue=5e-68,
Organism=Homo sapiens, GI21269877, Length=413, Percent_Identity=33.4140435835351, Blast_Score=192, Evalue=4e-49,
Organism=Homo sapiens, GI62240992, Length=413, Percent_Identity=33.4140435835351, Blast_Score=192, Evalue=4e-49,
Organism=Homo sapiens, GI10835051, Length=413, Percent_Identity=33.4140435835351, Blast_Score=192, Evalue=4e-49,
Organism=Homo sapiens, GI303304987, Length=413, Percent_Identity=33.4140435835351, Blast_Score=192, Evalue=5e-49,
Organism=Escherichia coli, GI1786737, Length=471, Percent_Identity=43.5244161358811, Blast_Score=384, Evalue=1e-108,
Organism=Caenorhabditis elegans, GI17509797, Length=327, Percent_Identity=32.7217125382263, Blast_Score=178, Evalue=5e-45,
Organism=Caenorhabditis elegans, GI17509795, Length=327, Percent_Identity=32.7217125382263, Blast_Score=178, Evalue=5e-45,
Organism=Saccharomyces cerevisiae, GI6324082, Length=274, Percent_Identity=39.051094890511, Blast_Score=188, Evalue=2e-48,
Organism=Drosophila melanogaster, GI19922218, Length=379, Percent_Identity=38.2585751978892, Blast_Score=238, Evalue=6e-63,
Organism=Drosophila melanogaster, GI19922364, Length=315, Percent_Identity=33.968253968254, Blast_Score=179, Evalue=3e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015803
- InterPro:   IPR015273
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF09190 DALR_2; PF01406 tRNA-synt_1e [H]

EC number: =6.1.1.16 [H]

Molecular weight: Translated: 53686; Mature: 53686

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITLYNTLTRQKEVFKPIEPGKVKMYVCGPTVYNYIHIGNARPAINYDVVRRYFEYQGYN
CEEEHHHHHHHHHHHCCCCCCCEEEEEECCCEEEEEEECCCCCCCCHHHHHHHHHHCCCC
VEYVSNFTDVDDKLIKRSQELNQSVPEIAEKYIAAFHEDVGALNVRKATSNPRVMDHMDD
EEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHH
IIQFIKDLVDQGYAYESGGDVYFRTRKFEGYGKLSHQSIDDLKVGARIDAGEHKEDALDF
HHHHHHHHHHCCCEECCCCCEEEEEEEECCCCCCCCCCHHHHHCCCCCCCCCCCHHHHHH
TLWKKAKPGEISWDSPFGEGRPGWHIECSVMAFHELGPTIDIHAGGSDLQFPHHENEIAQ
HHCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEHHHCCCEEEEECCCCCCCCCCCHHHHHH
SEAHNHAPFANYWMHNGFINIDNEKMSKSLGNFILVHDIIKEVDPDVLRFFMISVHYRSP
HHCCCCCCHHHHHHCCCEEEECHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHCCCC
INYNLELVESARSGLERIRNSYQLIEERAQIATNIENQQTYIDQIDAILNRFETVMNDDF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCC
NTANAITAWYDLAKLANKYVLENTTSTEVIDKFKAVYQIFSDVLGVPLKSKNADELLDED
CCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
VEKLIEERNEARKNKDFARADEIRDMLKSQNIILEDTPQGVRFKRG
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCEEEECCCCCCCCCCC
>Mature Secondary Structure
MITLYNTLTRQKEVFKPIEPGKVKMYVCGPTVYNYIHIGNARPAINYDVVRRYFEYQGYN
CEEEHHHHHHHHHHHCCCCCCCEEEEEECCCEEEEEEECCCCCCCCHHHHHHHHHHCCCC
VEYVSNFTDVDDKLIKRSQELNQSVPEIAEKYIAAFHEDVGALNVRKATSNPRVMDHMDD
EEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHH
IIQFIKDLVDQGYAYESGGDVYFRTRKFEGYGKLSHQSIDDLKVGARIDAGEHKEDALDF
HHHHHHHHHHCCCEECCCCCEEEEEEEECCCCCCCCCCHHHHHCCCCCCCCCCCHHHHHH
TLWKKAKPGEISWDSPFGEGRPGWHIECSVMAFHELGPTIDIHAGGSDLQFPHHENEIAQ
HHCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEHHHCCCEEEEECCCCCCCCCCCHHHHHH
SEAHNHAPFANYWMHNGFINIDNEKMSKSLGNFILVHDIIKEVDPDVLRFFMISVHYRSP
HHCCCCCCHHHHHHCCCEEEECHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHCCCC
INYNLELVESARSGLERIRNSYQLIEERAQIATNIENQQTYIDQIDAILNRFETVMNDDF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCC
NTANAITAWYDLAKLANKYVLENTTSTEVIDKFKAVYQIFSDVLGVPLKSKNADELLDED
CCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
VEKLIEERNEARKNKDFARADEIRDMLKSQNIILEDTPQGVRFKRG
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA