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The map label for this gene is treA [H]

Identifier: 57651356

GI number: 57651356

Start: 521961

End: 523601

Strand: Direct

Name: treA [H]

Synonym: SACOL0517

Alternate gene names: 57651356

Gene position: 521961-523601 (Clockwise)

Preceding gene: 57651355

Following gene: 57651357

Centisome position: 18.58

GC content: 36.26

Gene sequence:

>1641_bases
GTGTCGAAAGAAATAGATTGGAGAAAATCCGTTGTATATCAAATTTATCCTAAGTCGTTTAATGATACGACGGGGAATGG
TATAGGAGATATCAATGGAATTATAGAAAAATTGGATTATATCAAGTTATTGGGTGTTGATTATATTTGGTTAACACCAG
TGTATGAATCACCGATGAATGATAATGGCTATGATATCAGCAATTATTTAGAAATCAATGAAGACTTTGGAACGATGGAT
GATTTTGAAAAGTTAATCAAAGTTGCGCATCAAAAAGACTTGAAAGTGATGTTAGATATTGTCATTAATCATACGTCGAC
GGAGCATGAATGGTTTAAAGAAGCCCGTAAATCTAAAGATAACCCTTATAGAGATTATTACTTTTTCAGATCATCTGAAG
ACGGGCCGCCAACAAATTGGCATTCTAAATTCGGTGGTAATGCATGGAAGTATGATTCTGAGACAGATGAATATTATTTA
CATTTATTTGATGTCAGTCAAGCTGATTTAAATTGGGATAATCCGGAAGTACGTCAATCGTTATATCGCATAGTCAATCA
TTGGATAGACTTCGGCGTTGATGGTTTTCGATTTGATGTCATTAACTTAATTTCTAAAGGTGAATTTAAGGACTCTGACA
AAATAGGTAAAGAATTTTATACGGATGGTCCTAGAGTGCATGAGTTTCTGCATGAATTAAATCGTCAAACGTTTGGTAAC
ACTGACATGATGACTATAGGAGAAATGTCTTCGACGACGATTGAAAATTGTATTAAGTATACACAACCAGAACGCCAAGA
ATTGAATAGTGTTTTTAATTTTCATCATCTAAAGGTTGATTATGTTGATGGTGAAAAGTGGACAAATGCGAAGCTTGATT
TTCATAAGTTAAAGGAAATTCTGATGCAATGGCAACGAGGTATTTATGACGGTGGCGGATGGAACGCGATTTTCTGGTGT
AATCATGATCAGCCACGGGTAGTGTCTAGATTTGGTGATGATACGTCGGAAGAGATGAGGATACAAAGTGCTAAAATGTT
AGCTATCGCACTGCATATGTTGCAAGGGACGCCATATATTTACCAAGGTGAAGAAATTGGTATGACGGACCCACATTTTA
CATCAATAGCACAATATCGTGATGTTGAATCGATTAATGCCTACCATCAGTTGTTAAGTGAAGGGCATGCTGAAGCGGAT
GTGTTAGCGATTTTAGGACAGAAGTCACGAGACAATTCGAGAACGCCTATGCAATGGAGTGATGATGTTAATGCTGGATT
TACAGCTGGTAAGCCTTGGATTGATATTTCGGAAAATTATCATCAGGTCAACGTTAGACAAGCACTTCAGAATAAAGAGT
CTATTTTCTATACGTATCAAAAATTAATACAATTAAGACATACGCATGATATTATTACGTATGGAGACATTGTGCCACGT
TTTATGGATCATGATCATTTATTTGTTTATGAACGTCATTATAAGAATCAACAATGGCTAGTAATTGCGAATTTCTCAGC
ATCGGCTGTTGATTTGCCAGAAGGATTGGCTAGAGAAGGTTGTGTTGTGATTCAAACAGGCACAGTGGAAAATAATACGA
TAAGCGGGTTTGGTGCAATTGTAATCGAAACAAACGCGTAA

Upstream 100 bases:

>100_bases
TAGTAAACAAAAAGCGAAAGAAATTGTTGAAGATTAATAAAATAAAAAAGGGGCGTTCGTTATTTGGACGTCCTTTATTA
CGTTATAAGGTGGTAATTGT

Downstream 100 bases:

>100_bases
AATAAATTGAGTGGATGCGTTTATATGGCGAAACAAAAAAAGTTTATGAAGATTTATGAGGCGTTGAAAGAAGATATATT
AAACGGGCAGATTCAATATG

Product: alpha-amylase family protein

Products: NA

Alternate protein names: Alpha,alpha-phosphotrehalase [H]

Number of amino acids: Translated: 546; Mature: 545

Protein sequence:

>546_residues
MSKEIDWRKSVVYQIYPKSFNDTTGNGIGDINGIIEKLDYIKLLGVDYIWLTPVYESPMNDNGYDISNYLEINEDFGTMD
DFEKLIKVAHQKDLKVMLDIVINHTSTEHEWFKEARKSKDNPYRDYYFFRSSEDGPPTNWHSKFGGNAWKYDSETDEYYL
HLFDVSQADLNWDNPEVRQSLYRIVNHWIDFGVDGFRFDVINLISKGEFKDSDKIGKEFYTDGPRVHEFLHELNRQTFGN
TDMMTIGEMSSTTIENCIKYTQPERQELNSVFNFHHLKVDYVDGEKWTNAKLDFHKLKEILMQWQRGIYDGGGWNAIFWC
NHDQPRVVSRFGDDTSEEMRIQSAKMLAIALHMLQGTPYIYQGEEIGMTDPHFTSIAQYRDVESINAYHQLLSEGHAEAD
VLAILGQKSRDNSRTPMQWSDDVNAGFTAGKPWIDISENYHQVNVRQALQNKESIFYTYQKLIQLRHTHDIITYGDIVPR
FMDHDHLFVYERHYKNQQWLVIANFSASAVDLPEGLAREGCVVIQTGTVENNTISGFGAIVIETNA

Sequences:

>Translated_546_residues
MSKEIDWRKSVVYQIYPKSFNDTTGNGIGDINGIIEKLDYIKLLGVDYIWLTPVYESPMNDNGYDISNYLEINEDFGTMD
DFEKLIKVAHQKDLKVMLDIVINHTSTEHEWFKEARKSKDNPYRDYYFFRSSEDGPPTNWHSKFGGNAWKYDSETDEYYL
HLFDVSQADLNWDNPEVRQSLYRIVNHWIDFGVDGFRFDVINLISKGEFKDSDKIGKEFYTDGPRVHEFLHELNRQTFGN
TDMMTIGEMSSTTIENCIKYTQPERQELNSVFNFHHLKVDYVDGEKWTNAKLDFHKLKEILMQWQRGIYDGGGWNAIFWC
NHDQPRVVSRFGDDTSEEMRIQSAKMLAIALHMLQGTPYIYQGEEIGMTDPHFTSIAQYRDVESINAYHQLLSEGHAEAD
VLAILGQKSRDNSRTPMQWSDDVNAGFTAGKPWIDISENYHQVNVRQALQNKESIFYTYQKLIQLRHTHDIITYGDIVPR
FMDHDHLFVYERHYKNQQWLVIANFSASAVDLPEGLAREGCVVIQTGTVENNTISGFGAIVIETNA
>Mature_545_residues
SKEIDWRKSVVYQIYPKSFNDTTGNGIGDINGIIEKLDYIKLLGVDYIWLTPVYESPMNDNGYDISNYLEINEDFGTMDD
FEKLIKVAHQKDLKVMLDIVINHTSTEHEWFKEARKSKDNPYRDYYFFRSSEDGPPTNWHSKFGGNAWKYDSETDEYYLH
LFDVSQADLNWDNPEVRQSLYRIVNHWIDFGVDGFRFDVINLISKGEFKDSDKIGKEFYTDGPRVHEFLHELNRQTFGNT
DMMTIGEMSSTTIENCIKYTQPERQELNSVFNFHHLKVDYVDGEKWTNAKLDFHKLKEILMQWQRGIYDGGGWNAIFWCN
HDQPRVVSRFGDDTSEEMRIQSAKMLAIALHMLQGTPYIYQGEEIGMTDPHFTSIAQYRDVESINAYHQLLSEGHAEADV
LAILGQKSRDNSRTPMQWSDDVNAGFTAGKPWIDISENYHQVNVRQALQNKESIFYTYQKLIQLRHTHDIITYGDIVPRF
MDHDHLFVYERHYKNQQWLVIANFSASAVDLPEGLAREGCVVIQTGTVENNTISGFGAIVIETNA

Specific function: Unknown

COG id: COG0366

COG function: function code G; Glycosidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 13 family [H]

Homologues:

Organism=Homo sapiens, GI187423904, Length=561, Percent_Identity=27.9857397504456, Blast_Score=226, Evalue=5e-59,
Organism=Escherichia coli, GI1790687, Length=503, Percent_Identity=56.2624254473161, Blast_Score=598, Evalue=1e-172,
Organism=Escherichia coli, GI1786604, Length=215, Percent_Identity=27.906976744186, Blast_Score=84, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI25147709, Length=534, Percent_Identity=23.2209737827715, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI32565753, Length=378, Percent_Identity=23.2804232804233, Blast_Score=97, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6322245, Length=536, Percent_Identity=39.5522388059701, Blast_Score=372, Evalue=1e-104,
Organism=Saccharomyces cerevisiae, GI6321726, Length=538, Percent_Identity=38.8475836431227, Blast_Score=368, Evalue=1e-102,
Organism=Saccharomyces cerevisiae, GI6322241, Length=538, Percent_Identity=38.8475836431227, Blast_Score=359, Evalue=1e-100,
Organism=Saccharomyces cerevisiae, GI6322021, Length=538, Percent_Identity=38.8475836431227, Blast_Score=359, Evalue=1e-100,
Organism=Saccharomyces cerevisiae, GI6324416, Length=538, Percent_Identity=39.0334572490706, Blast_Score=358, Evalue=1e-100,
Organism=Saccharomyces cerevisiae, GI6321731, Length=556, Percent_Identity=37.410071942446, Blast_Score=341, Evalue=2e-94,
Organism=Saccharomyces cerevisiae, GI6319776, Length=556, Percent_Identity=37.2302158273381, Blast_Score=340, Evalue=4e-94,
Organism=Drosophila melanogaster, GI221330053, Length=590, Percent_Identity=31.6949152542373, Blast_Score=268, Evalue=5e-72,
Organism=Drosophila melanogaster, GI24583745, Length=542, Percent_Identity=34.1328413284133, Blast_Score=268, Evalue=1e-71,
Organism=Drosophila melanogaster, GI24586599, Length=545, Percent_Identity=31.9266055045872, Blast_Score=265, Evalue=5e-71,
Organism=Drosophila melanogaster, GI24586597, Length=538, Percent_Identity=32.1561338289963, Blast_Score=263, Evalue=3e-70,
Organism=Drosophila melanogaster, GI24586593, Length=529, Percent_Identity=31.758034026465, Blast_Score=262, Evalue=5e-70,
Organism=Drosophila melanogaster, GI24583747, Length=567, Percent_Identity=33.1569664902998, Blast_Score=259, Evalue=3e-69,
Organism=Drosophila melanogaster, GI24583749, Length=567, Percent_Identity=33.1569664902998, Blast_Score=259, Evalue=4e-69,
Organism=Drosophila melanogaster, GI24586591, Length=496, Percent_Identity=34.0725806451613, Blast_Score=250, Evalue=2e-66,
Organism=Drosophila melanogaster, GI45549022, Length=540, Percent_Identity=30, Blast_Score=244, Evalue=1e-64,
Organism=Drosophila melanogaster, GI24586589, Length=492, Percent_Identity=31.9105691056911, Blast_Score=235, Evalue=5e-62,
Organism=Drosophila melanogaster, GI24586587, Length=500, Percent_Identity=30, Blast_Score=214, Evalue=1e-55,
Organism=Drosophila melanogaster, GI281360393, Length=477, Percent_Identity=29.559748427673, Blast_Score=195, Evalue=7e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR006589
- InterPro:   IPR017853
- InterPro:   IPR013781
- InterPro:   IPR012769 [H]

Pfam domain/function: PF00128 Alpha-amylase [H]

EC number: =3.2.1.93 [H]

Molecular weight: Translated: 63515; Mature: 63383

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKEIDWRKSVVYQIYPKSFNDTTGNGIGDINGIIEKLDYIKLLGVDYIWLTPVYESPMN
CCCCCCCHHCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCC
DNGYDISNYLEINEDFGTMDDFEKLIKVAHQKDLKVMLDIVINHTSTEHEWFKEARKSKD
CCCCCCHHEEEECCCCCCHHHHHHHHHHHHHCCHHEEEHHHHCCCCCHHHHHHHHHHCCC
NPYRDYYFFRSSEDGPPTNWHSKFGGNAWKYDSETDEYYLHLFDVSQADLNWDNPEVRQS
CCCCEEEEEECCCCCCCCCCCHHCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHH
LYRIVNHWIDFGVDGFRFDVINLISKGEFKDSDKIGKEFYTDGPRVHEFLHELNRQTFGN
HHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCC
TDMMTIGEMSSTTIENCIKYTQPERQELNSVFNFHHLKVDYVDGEKWTNAKLDFHKLKEI
CCCEEECCCCHHHHHHHHHCCCCHHHHHHHHHCEEEEEEEEECCCCCCCCCCCHHHHHHH
LMQWQRGIYDGGGWNAIFWCNHDQPRVVSRFGDDTSEEMRIQSAKMLAIALHMLQGTPYI
HHHHHHCCCCCCCCEEEEEECCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCEE
YQGEEIGMTDPHFTSIAQYRDVESINAYHQLLSEGHAEADVLAILGQKSRDNSRTPMQWS
EECCCCCCCCCCHHHHHHHHCHHHHHHHHHHHHCCCCCHHHHEEECCCCCCCCCCCCCCC
DDVNAGFTAGKPWIDISENYHQVNVRQALQNKESIFYTYQKLIQLRHTHDIITYGDIVPR
CCCCCCCCCCCCCEECCCCCEEEHHHHHHCCCHHHHHHHHHHHHHHHHCCEEEHHHHHHH
FMDHDHLFVYERHYKNQQWLVIANFSASAVDLPEGLAREGCVVIQTGTVENNTISGFGAI
HCCCCEEEEEEECCCCCEEEEEECCCCCCCCCCHHHHHCCEEEEEECCCCCCCCCCEEEE
VIETNA
EEEECC
>Mature Secondary Structure 
SKEIDWRKSVVYQIYPKSFNDTTGNGIGDINGIIEKLDYIKLLGVDYIWLTPVYESPMN
CCCCCCHHCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCC
DNGYDISNYLEINEDFGTMDDFEKLIKVAHQKDLKVMLDIVINHTSTEHEWFKEARKSKD
CCCCCCHHEEEECCCCCCHHHHHHHHHHHHHCCHHEEEHHHHCCCCCHHHHHHHHHHCCC
NPYRDYYFFRSSEDGPPTNWHSKFGGNAWKYDSETDEYYLHLFDVSQADLNWDNPEVRQS
CCCCEEEEEECCCCCCCCCCCHHCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHH
LYRIVNHWIDFGVDGFRFDVINLISKGEFKDSDKIGKEFYTDGPRVHEFLHELNRQTFGN
HHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCC
TDMMTIGEMSSTTIENCIKYTQPERQELNSVFNFHHLKVDYVDGEKWTNAKLDFHKLKEI
CCCEEECCCCHHHHHHHHHCCCCHHHHHHHHHCEEEEEEEEECCCCCCCCCCCHHHHHHH
LMQWQRGIYDGGGWNAIFWCNHDQPRVVSRFGDDTSEEMRIQSAKMLAIALHMLQGTPYI
HHHHHHCCCCCCCCEEEEEECCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCEE
YQGEEIGMTDPHFTSIAQYRDVESINAYHQLLSEGHAEADVLAILGQKSRDNSRTPMQWS
EECCCCCCCCCCHHHHHHHHCHHHHHHHHHHHHCCCCCHHHHEEECCCCCCCCCCCCCCC
DDVNAGFTAGKPWIDISENYHQVNVRQALQNKESIFYTYQKLIQLRHTHDIITYGDIVPR
CCCCCCCCCCCCCEECCCCCEEEHHHHHHCCCHHHHHHHHHHHHHHHHCCEEEHHHHHHH
FMDHDHLFVYERHYKNQQWLVIANFSASAVDLPEGLAREGCVVIQTGTVENNTISGFGAI
HCCCCEEEEEEECCCCCEEEEEECCCCCCCCCCHHHHHCCEEEEEECCCCCCCCCCEEEE
VIETNA
EEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7651129; 8969503; 9384377; 7751281 [H]