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The map label for this gene is gltD [H]

Identifier: 57651354

GI number: 57651354

Start: 518175

End: 519638

Strand: Direct

Name: gltD [H]

Synonym: SACOL0515

Alternate gene names: 57651354

Gene position: 518175-519638 (Clockwise)

Preceding gene: 57651353

Following gene: 57651355

Centisome position: 18.44

GC content: 38.25

Gene sequence:

>1464_bases
ATGGGTGAATTTAAAGGATTTATGAAGTATGACAAACAGTACTTAGGTGAATTATCACTGGTAGACCGTTTGAAGCATCA
TAAAGCATATCAACAACGATTTACTAAAGAAGATGCCTCTATCCAAGGTGCACGATGTATGGATTGTGGAACGCCGTTTT
GTCAAACCGGACAACAGTATGGTAGGGAAACAATAGGTTGTCCAATTGGAAACTACATTCCTGAATGGAACGACTTAGTG
TATCATCAAGATTTTAAAACTGCTTATGAACGCTTAAGCGAAACAAATAACTTTCCTGACTTTACAGGGCGTGTATGTCC
TGCACCATGCGAAAGTGCTTGTGTGATGAAGATTAATAGAGAATCGATTGCGATTAAAGGTATTGAACGCACAATTATTG
ATGAAGCTTTTGAAAATGGTTGGGTAGCGCCGAAAGTTCCGAGTCGCCGTAGAGATGAAAAAGTGGCAATCGTTGGAAGC
GGTCCAGCAGGATTAGCTGCTGCTGAAGAACTTAATCTACTAGGATATCAAGTAACTATTTATGAACGTGCTAGAGAATC
AGGCGGTTTATTAATGTATGGTATTCCGAATATGAAACTTGATAAAGATGTGGTTCGACGTCGTATTAAGTTAATGGAAG
AAGCGGGCATTACTTTCATTAATGGTGTTGAAGTCGGCGTTGATATTGATAAAGCAACGTTAGAATCTGAGTATGATGCC
ATTATATTATGTACTGGTGCACAAAAAGGTAGAGATTTACCTTTAGAAGGACGCATGGGTGATGGTATACATTTCGCTAT
GGATTATTTAACTGAACAAACGCAGTTGTTAAATGGAGAAATTGATGATATAACAATAACTGCAAAAGATAAGAATGTCA
TTATCATTGGTGCTGGTGATACAGGGGCAGACTGTGTAGCGACAGCATTAAGAGAAAATTGTAAATCGATTGTTCAATTT
AATAAATATACGAAATTGCCAGAAGCAATTACATTTACAGAAAATGCATCATGGCCTTTAGCAATGCCGGTGTTTAAAAT
GGACTATGCGCACCAAGAGTACGAAGCTAAGTTTGGTAAGGAACCACGTGCATATGGTGTTCAAACAATGCGTTACGATG
TTGACGATAAAGGACACATACGTGGTTTGTATACTCAAATTTTAGAGCAAGGCGAAAATGGTATGGTCATGAAAGAAGGA
CCTGAAAGATTTTGGCCTGCTGACCTTGTATTATTATCAATCGGCTTCGAAGGTACAGAACCAACAGTACCGAATGCTTT
TAACATTAAAACGGATAGAAATCGAATCGTGGCGGATGATACAAACTATCAAACTAATAATGAAAAGGTATTTGCTGCTG
GAGATGCTAGACGTGGTCAAAGTTTAGTTGTATGGGCAATTAAAGAAGGTAGAGGCGTAGCGAAAGCAGTAGATCAGTAT
TTAGCTAGTAAAGTTTGTGTATAA

Upstream 100 bases:

>100_bases
ATGAAGATGAAGCGATGTTAGCTGCATTTTACGATGACAGTAAAACAATCGATGCTAAACATAAACCAGCCGTTGTGTAT
TAAGGAAAGGGGGAGATACG

Downstream 100 bases:

>100_bases
TCTTTGTATGGAAATGGTGGTTACGTTGACGTTGTGACATGCTGAATCGAGTTTGAAAAAATCTAGTATCTATCAACGTC
ACATGCCATCTTTGTAACCT

Product: glutamate synthase subunit beta

Products: NA

Alternate protein names: NADPH-GOGAT [H]

Number of amino acids: Translated: 487; Mature: 486

Protein sequence:

>487_residues
MGEFKGFMKYDKQYLGELSLVDRLKHHKAYQQRFTKEDASIQGARCMDCGTPFCQTGQQYGRETIGCPIGNYIPEWNDLV
YHQDFKTAYERLSETNNFPDFTGRVCPAPCESACVMKINRESIAIKGIERTIIDEAFENGWVAPKVPSRRRDEKVAIVGS
GPAGLAAAEELNLLGYQVTIYERARESGGLLMYGIPNMKLDKDVVRRRIKLMEEAGITFINGVEVGVDIDKATLESEYDA
IILCTGAQKGRDLPLEGRMGDGIHFAMDYLTEQTQLLNGEIDDITITAKDKNVIIIGAGDTGADCVATALRENCKSIVQF
NKYTKLPEAITFTENASWPLAMPVFKMDYAHQEYEAKFGKEPRAYGVQTMRYDVDDKGHIRGLYTQILEQGENGMVMKEG
PERFWPADLVLLSIGFEGTEPTVPNAFNIKTDRNRIVADDTNYQTNNEKVFAAGDARRGQSLVVWAIKEGRGVAKAVDQY
LASKVCV

Sequences:

>Translated_487_residues
MGEFKGFMKYDKQYLGELSLVDRLKHHKAYQQRFTKEDASIQGARCMDCGTPFCQTGQQYGRETIGCPIGNYIPEWNDLV
YHQDFKTAYERLSETNNFPDFTGRVCPAPCESACVMKINRESIAIKGIERTIIDEAFENGWVAPKVPSRRRDEKVAIVGS
GPAGLAAAEELNLLGYQVTIYERARESGGLLMYGIPNMKLDKDVVRRRIKLMEEAGITFINGVEVGVDIDKATLESEYDA
IILCTGAQKGRDLPLEGRMGDGIHFAMDYLTEQTQLLNGEIDDITITAKDKNVIIIGAGDTGADCVATALRENCKSIVQF
NKYTKLPEAITFTENASWPLAMPVFKMDYAHQEYEAKFGKEPRAYGVQTMRYDVDDKGHIRGLYTQILEQGENGMVMKEG
PERFWPADLVLLSIGFEGTEPTVPNAFNIKTDRNRIVADDTNYQTNNEKVFAAGDARRGQSLVVWAIKEGRGVAKAVDQY
LASKVCV
>Mature_486_residues
GEFKGFMKYDKQYLGELSLVDRLKHHKAYQQRFTKEDASIQGARCMDCGTPFCQTGQQYGRETIGCPIGNYIPEWNDLVY
HQDFKTAYERLSETNNFPDFTGRVCPAPCESACVMKINRESIAIKGIERTIIDEAFENGWVAPKVPSRRRDEKVAIVGSG
PAGLAAAEELNLLGYQVTIYERARESGGLLMYGIPNMKLDKDVVRRRIKLMEEAGITFINGVEVGVDIDKATLESEYDAI
ILCTGAQKGRDLPLEGRMGDGIHFAMDYLTEQTQLLNGEIDDITITAKDKNVIIIGAGDTGADCVATALRENCKSIVQFN
KYTKLPEAITFTENASWPLAMPVFKMDYAHQEYEAKFGKEPRAYGVQTMRYDVDDKGHIRGLYTQILEQGENGMVMKEGP
ERFWPADLVLLSIGFEGTEPTVPNAFNIKTDRNRIVADDTNYQTNNEKVFAAGDARRGQSLVVWAIKEGRGVAKAVDQYL
ASKVCV

Specific function: Unknown

COG id: COG0493

COG function: function code ER; NADPH-dependent glutamate synthase beta chain and related oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutamate synthase family [H]

Homologues:

Organism=Homo sapiens, GI119943098, Length=469, Percent_Identity=24.5202558635394, Blast_Score=91, Evalue=2e-18,
Organism=Escherichia coli, GI1788811, Length=468, Percent_Identity=33.5470085470085, Blast_Score=234, Evalue=1e-62,
Organism=Escherichia coli, GI1789606, Length=463, Percent_Identity=33.4773218142549, Blast_Score=230, Evalue=2e-61,
Organism=Escherichia coli, GI87082180, Length=430, Percent_Identity=33.7209302325581, Blast_Score=192, Evalue=6e-50,
Organism=Escherichia coli, GI1788468, Length=454, Percent_Identity=28.1938325991189, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI1789243, Length=464, Percent_Identity=24.3534482758621, Blast_Score=95, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17570289, Length=501, Percent_Identity=41.9161676646707, Blast_Score=384, Evalue=1e-107,
Organism=Caenorhabditis elegans, GI71984108, Length=482, Percent_Identity=24.0663900414938, Blast_Score=82, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6320030, Length=485, Percent_Identity=41.6494845360825, Blast_Score=394, Evalue=1e-110,
Organism=Drosophila melanogaster, GI28574881, Length=487, Percent_Identity=47.4332648870637, Blast_Score=448, Evalue=1e-126,
Organism=Drosophila melanogaster, GI24665539, Length=487, Percent_Identity=47.4332648870637, Blast_Score=448, Evalue=1e-126,
Organism=Drosophila melanogaster, GI24665547, Length=487, Percent_Identity=47.4332648870637, Blast_Score=447, Evalue=1e-126,
Organism=Drosophila melanogaster, GI24665543, Length=487, Percent_Identity=47.4332648870637, Blast_Score=447, Evalue=1e-126,
Organism=Drosophila melanogaster, GI24640763, Length=473, Percent_Identity=24.3128964059197, Blast_Score=89, Evalue=9e-18,
Organism=Drosophila melanogaster, GI18858217, Length=473, Percent_Identity=24.3128964059197, Blast_Score=89, Evalue=9e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR012285
- InterPro:   IPR006005
- InterPro:   IPR009051
- InterPro:   IPR016040
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.4.1.13 [H]

Molecular weight: Translated: 54428; Mature: 54297

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGEFKGFMKYDKQYLGELSLVDRLKHHKAYQQRFTKEDASIQGARCMDCGTPFCQTGQQY
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCHHHCHHHH
GRETIGCPIGNYIPEWNDLVYHQDFKTAYERLSETNNFPDFTGRVCPAPCESACVMKINR
CCCCCCCCCCCCCCCCCCEEEECHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECC
ESIAIKGIERTIIDEAFENGWVAPKVPSRRRDEKVAIVGSGPAGLAAAEELNLLGYQVTI
CEEEEEHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHEEEEEEE
YERARESGGLLMYGIPNMKLDKDVVRRRIKLMEEAGITFINGVEVGVDIDKATLESEYDA
EEHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCEEEECEEEEEECCHHHHCCCCCE
IILCTGAQKGRDLPLEGRMGDGIHFAMDYLTEQTQLLNGEIDDITITAKDKNVIIIGAGD
EEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEECCC
TGADCVATALRENCKSIVQFNKYTKLPEAITFTENASWPLAMPVFKMDYAHQEYEAKFGK
CCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEECCHHHHHHHHHHHHHHCCC
EPRAYGVQTMRYDVDDKGHIRGLYTQILEQGENGMVMKEGPERFWPADLVLLSIGFEGTE
CCHHCCCEEEEECCCCCCCHHHHHHHHHHCCCCCEEECCCCCCCCCCEEEEEEECCCCCC
PTVPNAFNIKTDRNRIVADDTNYQTNNEKVFAAGDARRGQSLVVWAIKEGRGVAKAVDQY
CCCCCEEEEECCCCEEEECCCCCCCCCCEEEEECCCCCCCEEEEEEEECCCCHHHHHHHH
LASKVCV
HHHHCCC
>Mature Secondary Structure 
GEFKGFMKYDKQYLGELSLVDRLKHHKAYQQRFTKEDASIQGARCMDCGTPFCQTGQQY
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCHHHCHHHH
GRETIGCPIGNYIPEWNDLVYHQDFKTAYERLSETNNFPDFTGRVCPAPCESACVMKINR
CCCCCCCCCCCCCCCCCCEEEECHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECC
ESIAIKGIERTIIDEAFENGWVAPKVPSRRRDEKVAIVGSGPAGLAAAEELNLLGYQVTI
CEEEEEHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHEEEEEEE
YERARESGGLLMYGIPNMKLDKDVVRRRIKLMEEAGITFINGVEVGVDIDKATLESEYDA
EEHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCEEEECEEEEEECCHHHHCCCCCE
IILCTGAQKGRDLPLEGRMGDGIHFAMDYLTEQTQLLNGEIDDITITAKDKNVIIIGAGD
EEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEECCC
TGADCVATALRENCKSIVQFNKYTKLPEAITFTENASWPLAMPVFKMDYAHQEYEAKFGK
CCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEECCHHHHHHHHHHHHHHCCC
EPRAYGVQTMRYDVDDKGHIRGLYTQILEQGENGMVMKEGPERFWPADLVLLSIGFEGTE
CCHHCCCEEEEECCCCCCCHHHHHHHHHHCCCCCEEECCCCCCCCCCEEEEEEECCCCCC
PTVPNAFNIKTDRNRIVADDTNYQTNNEKVFAAGDARRGQSLVVWAIKEGRGVAKAVDQY
CCCCCEEEEECCCCEEEECCCCCCCCCCEEEEECCCCCCCEEEEEEEECCCCHHHHHHHH
LASKVCV
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 11029411 [H]