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The map label for this gene is yhdH [H]

Identifier: 57651340

GI number: 57651340

Start: 501148

End: 502485

Strand: Direct

Name: yhdH [H]

Synonym: SACOL0501

Alternate gene names: 57651340

Gene position: 501148-502485 (Clockwise)

Preceding gene: 57651339

Following gene: 57651341

Centisome position: 17.84

GC content: 34.75

Gene sequence:

>1338_bases
ATGAAAAGACAACAATCACAATGGAAGTCATCAACTGGATTTATTTTAGCTAGTGCGGGTTCTGCAATCGGTCTTGGTGC
CATGTGGAAATTCCCATATATGGCAGGGATTTATGGCGGCGGTGCCTTTCTAGCTATGTTCTTAATATTCACCATTTTTG
TTGGGTTGCCATTACTCATTATGGAATTCACTGTTGGGAAAATGGGACGGACATATACAACACAAATATATAGTAAATTA
ACTGGTAAAAAATGGCTCAATATCATTGGCTGGAACGGTAATTTGGCAGTGTTTATTTTATTTGGCTTCTATAGTGTTAT
CGGTGGTTGGATTGTCATTTACATCGGACAAGTATTATGGCAATTAGTTATATTTCAACGCATCAATCATCTCCAAGAAA
TGAATTTTGAAGCGGTAATATCAAATCCTTGGTTAACCGTTCTAGGGCAAGGTATATTCATATTCGCTACGATGATTATT
GTCATGTTAGGTGTTGAAAAAGGATTAGAAAAGGCATCGAAAGTTATGATGCCATTGCTGTTTGTCTTTTTAATCGTCAT
TGTGATTAAGTCTTTAACATTAGATGGCGCCTTAGAAGGTGTGAAATTTATTTTACAACCAAGAGTATCAGAGATTACTG
CTGATGGCATCTTGTTTGCGCTAGGTCAATCATTCTTTACGTTATCATTAGGAACTACAGGTATGATTACTTATGCGAGT
TATGCCTCTAAAGACATGACGATTAAGTCATCAGCTATTTCTATCGTTGTTATGAATATCTTTGTATCTGTATTGGCAGG
TCTAGCTATATTTCCGGCTTTACATAGTTTTGGCTATGAACCACAAGAAGGGCCTGGATTATTATTTAAAGTACTGCCAA
TGGTCTTTAGTCAAATGCATCTAGGCACATTATTCTATTTGGGATTCTTAGTGCTGTTCTTATTTGCGGCTTTAACGTCA
TCTATTTCTTTATTAGAATTAAATGTTTCTAACTTCACGAAGAATGACAATACAAAACGTAAAAAAGTCGCAGTGATCGG
TAGTATTTTAGTATTTATCATTAGTATTCCAGCAACCTTATCTTTTGGTATCTTAAAAGATGTAAGATTCGGTGCGGGAA
CGATTTTTGATAATATGGATTTCATCGTTTCGAATGTATTGATGCCATTAGGCGCATTAGGTACTACGCTTGTCGTAGGA
CAATTATTAGATAAAAAATTATTACAACAATATTTTGGTAAAGATCGATTTAGATTATTCAGTGGTTGGTATTACTTAAT
TAAGTATGCGATGCCTGTCGTTATTATTTTAGTCTTTATCGTGCAATTATTTAGTTAA

Upstream 100 bases:

>100_bases
GAAACAATTTTGATGCAGGTGTATTGCATGTTATTTACATACATGTTAGAGTGTTACTTAAACACGTAGACGCTTTAACG
CTTTAAAGGAGATGTGAATG

Downstream 100 bases:

>100_bases
TATATAGAAGCATCTGACACACAAGTATTTGTGTTGCTCAGGTGTTTTTTTGTTTGGAATTGAAAATTTAGTACTGGTTC
TGAATTAATCGAAACTTAGA

Product: sodium-dependent transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 445; Mature: 445

Protein sequence:

>445_residues
MKRQQSQWKSSTGFILASAGSAIGLGAMWKFPYMAGIYGGGAFLAMFLIFTIFVGLPLLIMEFTVGKMGRTYTTQIYSKL
TGKKWLNIIGWNGNLAVFILFGFYSVIGGWIVIYIGQVLWQLVIFQRINHLQEMNFEAVISNPWLTVLGQGIFIFATMII
VMLGVEKGLEKASKVMMPLLFVFLIVIVIKSLTLDGALEGVKFILQPRVSEITADGILFALGQSFFTLSLGTTGMITYAS
YASKDMTIKSSAISIVVMNIFVSVLAGLAIFPALHSFGYEPQEGPGLLFKVLPMVFSQMHLGTLFYLGFLVLFLFAALTS
SISLLELNVSNFTKNDNTKRKKVAVIGSILVFIISIPATLSFGILKDVRFGAGTIFDNMDFIVSNVLMPLGALGTTLVVG
QLLDKKLLQQYFGKDRFRLFSGWYYLIKYAMPVVIILVFIVQLFS

Sequences:

>Translated_445_residues
MKRQQSQWKSSTGFILASAGSAIGLGAMWKFPYMAGIYGGGAFLAMFLIFTIFVGLPLLIMEFTVGKMGRTYTTQIYSKL
TGKKWLNIIGWNGNLAVFILFGFYSVIGGWIVIYIGQVLWQLVIFQRINHLQEMNFEAVISNPWLTVLGQGIFIFATMII
VMLGVEKGLEKASKVMMPLLFVFLIVIVIKSLTLDGALEGVKFILQPRVSEITADGILFALGQSFFTLSLGTTGMITYAS
YASKDMTIKSSAISIVVMNIFVSVLAGLAIFPALHSFGYEPQEGPGLLFKVLPMVFSQMHLGTLFYLGFLVLFLFAALTS
SISLLELNVSNFTKNDNTKRKKVAVIGSILVFIISIPATLSFGILKDVRFGAGTIFDNMDFIVSNVLMPLGALGTTLVVG
QLLDKKLLQQYFGKDRFRLFSGWYYLIKYAMPVVIILVFIVQLFS
>Mature_445_residues
MKRQQSQWKSSTGFILASAGSAIGLGAMWKFPYMAGIYGGGAFLAMFLIFTIFVGLPLLIMEFTVGKMGRTYTTQIYSKL
TGKKWLNIIGWNGNLAVFILFGFYSVIGGWIVIYIGQVLWQLVIFQRINHLQEMNFEAVISNPWLTVLGQGIFIFATMII
VMLGVEKGLEKASKVMMPLLFVFLIVIVIKSLTLDGALEGVKFILQPRVSEITADGILFALGQSFFTLSLGTTGMITYAS
YASKDMTIKSSAISIVVMNIFVSVLAGLAIFPALHSFGYEPQEGPGLLFKVLPMVFSQMHLGTLFYLGFLVLFLFAALTS
SISLLELNVSNFTKNDNTKRKKVAVIGSILVFIISIPATLSFGILKDVRFGAGTIFDNMDFIVSNVLMPLGALGTTLVVG
QLLDKKLLQQYFGKDRFRLFSGWYYLIKYAMPVVIILVFIVQLFS

Specific function: Putative sodium-dependent transporter [H]

COG id: COG0733

COG function: function code R; Na+-dependent transporters of the SNF family

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family [H]

Homologues:

Organism=Homo sapiens, GI33354281, Length=305, Percent_Identity=27.2131147540984, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI7657587, Length=373, Percent_Identity=25.201072386059, Blast_Score=108, Evalue=7e-24,
Organism=Homo sapiens, GI194018524, Length=297, Percent_Identity=26.5993265993266, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI11181770, Length=309, Percent_Identity=26.537216828479, Blast_Score=106, Evalue=6e-23,
Organism=Homo sapiens, GI51468073, Length=295, Percent_Identity=26.1016949152542, Blast_Score=105, Evalue=8e-23,
Organism=Homo sapiens, GI58219014, Length=302, Percent_Identity=26.8211920529801, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI4507043, Length=499, Percent_Identity=23.0460921843687, Blast_Score=99, Evalue=8e-21,
Organism=Homo sapiens, GI188528618, Length=366, Percent_Identity=24.5901639344262, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI134304856, Length=400, Percent_Identity=26.25, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI21361581, Length=409, Percent_Identity=22.4938875305623, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI197276623, Length=350, Percent_Identity=24.8571428571429, Blast_Score=94, Evalue=4e-19,
Organism=Homo sapiens, GI54607094, Length=350, Percent_Identity=24.8571428571429, Blast_Score=94, Evalue=4e-19,
Organism=Homo sapiens, GI289191351, Length=507, Percent_Identity=24.2603550295858, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI4557046, Length=507, Percent_Identity=24.2603550295858, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI289191377, Length=509, Percent_Identity=24.1650294695481, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI12408638, Length=291, Percent_Identity=25.7731958762887, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI21361693, Length=128, Percent_Identity=30.46875, Blast_Score=76, Evalue=7e-14,
Organism=Homo sapiens, GI226437581, Length=252, Percent_Identity=25, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI197276625, Length=131, Percent_Identity=32.824427480916, Blast_Score=67, Evalue=5e-11,
Organism=Homo sapiens, GI55749589, Length=279, Percent_Identity=23.2974910394265, Blast_Score=66, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17554804, Length=352, Percent_Identity=25.2840909090909, Blast_Score=93, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI25146584, Length=419, Percent_Identity=24.8210023866348, Blast_Score=92, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17555248, Length=429, Percent_Identity=24.4755244755245, Blast_Score=89, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI133952791, Length=65, Percent_Identity=44.6153846153846, Blast_Score=65, Evalue=7e-11,
Organism=Drosophila melanogaster, GI17136952, Length=379, Percent_Identity=27.1767810026385, Blast_Score=119, Evalue=5e-27,
Organism=Drosophila melanogaster, GI281364394, Length=379, Percent_Identity=27.1767810026385, Blast_Score=116, Evalue=2e-26,
Organism=Drosophila melanogaster, GI28574704, Length=379, Percent_Identity=27.1767810026385, Blast_Score=116, Evalue=2e-26,
Organism=Drosophila melanogaster, GI17136950, Length=379, Percent_Identity=27.1767810026385, Blast_Score=116, Evalue=2e-26,
Organism=Drosophila melanogaster, GI28574702, Length=379, Percent_Identity=27.1767810026385, Blast_Score=116, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24762620, Length=410, Percent_Identity=25.3658536585366, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24582567, Length=315, Percent_Identity=26.984126984127, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI24639516, Length=296, Percent_Identity=26.3513513513513, Blast_Score=99, Evalue=6e-21,
Organism=Drosophila melanogaster, GI24639514, Length=296, Percent_Identity=26.3513513513513, Blast_Score=99, Evalue=8e-21,
Organism=Drosophila melanogaster, GI221329674, Length=295, Percent_Identity=26.4406779661017, Blast_Score=99, Evalue=8e-21,
Organism=Drosophila melanogaster, GI45551183, Length=390, Percent_Identity=25.3846153846154, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI45550877, Length=390, Percent_Identity=25.3846153846154, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI19921936, Length=367, Percent_Identity=25.3405994550409, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24661428, Length=364, Percent_Identity=24.7252747252747, Blast_Score=92, Evalue=6e-19,
Organism=Drosophila melanogaster, GI45551088, Length=406, Percent_Identity=23.8916256157635, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24652942, Length=406, Percent_Identity=23.8916256157635, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI281364136, Length=422, Percent_Identity=22.7488151658768, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24655079, Length=298, Percent_Identity=23.8255033557047, Blast_Score=80, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000175 [H]

Pfam domain/function: PF00209 SNF [H]

EC number: NA

Molecular weight: Translated: 49225; Mature: 49225

Theoretical pI: Translated: 10.16; Mature: 10.16

Prosite motif: PS00610 NA_NEUROTRAN_SYMP_1 ; PS50267 NA_NEUROTRAN_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRQQSQWKSSTGFILASAGSAIGLGAMWKFPYMAGIYGGGAFLAMFLIFTIFVGLPLLI
CCCCHHHHCCCCCEEEEECCCCCCCCHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHHH
MEFTVGKMGRTYTTQIYSKLTGKKWLNIIGWNGNLAVFILFGFYSVIGGWIVIYIGQVLW
HHHHHHHCCCHHHHHHHHHHCCHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
QLVIFQRINHLQEMNFEAVISNPWLTVLGQGIFIFATMIIVMLGVEKGLEKASKVMMPLL
HHHHHHHHHHHHHCCCHHEECCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FVFLIVIVIKSLTLDGALEGVKFILQPRVSEITADGILFALGQSFFTLSLGTTGMITYAS
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHEEEECCCCCHHHHHH
YASKDMTIKSSAISIVVMNIFVSVLAGLAIFPALHSFGYEPQEGPGLLFKVLPMVFSQMH
HCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
LGTLFYLGFLVLFLFAALTSSISLLELNVSNFTKNDNTKRKKVAVIGSILVFIISIPATL
HHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
SFGILKDVRFGAGTIFDNMDFIVSNVLMPLGALGTTLVVGQLLDKKLLQQYFGKDRFRLF
HHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
SGWYYLIKYAMPVVIILVFIVQLFS
HHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MKRQQSQWKSSTGFILASAGSAIGLGAMWKFPYMAGIYGGGAFLAMFLIFTIFVGLPLLI
CCCCHHHHCCCCCEEEEECCCCCCCCHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHHH
MEFTVGKMGRTYTTQIYSKLTGKKWLNIIGWNGNLAVFILFGFYSVIGGWIVIYIGQVLW
HHHHHHHCCCHHHHHHHHHHCCHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
QLVIFQRINHLQEMNFEAVISNPWLTVLGQGIFIFATMIIVMLGVEKGLEKASKVMMPLL
HHHHHHHHHHHHHCCCHHEECCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FVFLIVIVIKSLTLDGALEGVKFILQPRVSEITADGILFALGQSFFTLSLGTTGMITYAS
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHEEEECCCCCHHHHHH
YASKDMTIKSSAISIVVMNIFVSVLAGLAIFPALHSFGYEPQEGPGLLFKVLPMVFSQMH
HCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
LGTLFYLGFLVLFLFAALTSSISLLELNVSNFTKNDNTKRKKVAVIGSILVFIISIPATL
HHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
SFGILKDVRFGAGTIFDNMDFIVSNVLMPLGALGTTLVVGQLLDKKLLQQYFGKDRFRLF
HHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
SGWYYLIKYAMPVVIILVFIVQLFS
HHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]