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The map label for this gene is argJ

Identifier: 57651184

GI number: 57651184

Start: 192647

End: 193888

Strand: Reverse

Name: argJ

Synonym: SACOL0168

Alternate gene names: 57651184

Gene position: 193888-192647 (Counterclockwise)

Preceding gene: 57651185

Following gene: 57651183

Centisome position: 6.9

GC content: 38.08

Gene sequence:

>1242_bases
ATGAAACATCAAGAAACGACATCACAACAATATAACTTTTCAATTATTAAACATGGCGATATCAGTACACCTCAAGGCTT
CACGGCTGGTGGTATGCACATCGGTTTACGCGCTAACAAAAAAGACTTTGGGTGGATTTACTCATCGTCTTTGGCAAGTG
CAGCTGCCGTATATACTTTAAATCAGTTTAAAGCTGCACCACTTATTGTCACTGAAGACACTTTACAAAAGTCTAAAGGA
AAATTACAAGCACTTGTTGTTAATTCAGCTAATGCAAATTCTTGTACCGGTCAACAAGGCATAGATGATGCACGACAAAC
ACAAACATGGGTTGCTCAACAACTTCAAATACCATCTGAGCATGTTGCTGTTGCTTCAACTGGGGTCATTGGTGAATATT
TGCCTATGGATAAAATTAAGACTGGGACCGAACATATTAAGGATGCTAATTTTGCAACGCCAGGTGCGTTTAACGAGGCA
ATTTTAACAACTGATACCTGTACAAAACATATCGCTGTATCACTAAAAATCGATGGTAAAACCGTTACAATTGGTGGTAG
CACCAAAGGTTCAGGTATGATTCACCCAAATATGGCTACCATGCTTGCTTTTATAACAACCGATGCATCGATTGAATCGA
ATACACTTCATCAATTATTAAAATCTTCGACTGACCATACATTTAATATGATTACTGTTGATGGCGATACAAGTACAAAT
GACATGGTATTAGTCATGGCAAATCACCAAGTTGAACACCAAATACTTAGTCAAGACCATCCACAATGGGAAACATTTGT
TGATGCATTCAATTTTGTCTGTACATTTTTAGCTAAAGCTATAGCCAGAGATGGCGAAGGCGCAACAAAGTTAATCAGCG
TCAATGTGTCAGGCGCTAAATCAATATCAGATGCAAGAAAAATCGGTAAAACTATCGTAAGTTCAAATCTAGTAAAATCA
GCTATTTTTGGCGAAGATGCCAATTTTGGTCGAATCATTACAGCTATTGGCTACAGCGGATGTGAAATTGATCCTAACTG
CACATATGTTCAACTGAACCAAATACCTGTCGTTGATAAAGGTATGGCTGTACTATTTGATGAGCAAGCTATGTCGAATA
CATTAACTCATGAAAATGTCACAATTGACGTTCAGCTTGGTTTAGGTAACGCTGCAGCGACTGCATACGGTTGTGATTTA
TCCTATGATTATGTGCGTATCAACGCATCATATCGAACATAA

Upstream 100 bases:

>100_bases
GCGCAAGTGGGCAAGCCATTCAAAATTTAAATATATTATATGATTTTGAAGTGACGACTGGCCTAAATCAATCACCAGTT
TATCCATAAGGGGTGTTAGA

Downstream 100 bases:

>100_bases
GGTGGTGTTGGTTAGATGAAATTTATTGTCATTAAAATTGGTGGCAGTACACTTAGTGACATGCATCCATCAATTATTAA
CAACATTAAGCATTTACGAT

Product: bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein

Products: NA

Alternate protein names: Glutamate N-acetyltransferase; Ornithine acetyltransferase; OATase; Ornithine transacetylase; Amino-acid acetyltransferase; N-acetylglutamate synthase; AGS

Number of amino acids: Translated: 413; Mature: 413

Protein sequence:

>413_residues
MKHQETTSQQYNFSIIKHGDISTPQGFTAGGMHIGLRANKKDFGWIYSSSLASAAAVYTLNQFKAAPLIVTEDTLQKSKG
KLQALVVNSANANSCTGQQGIDDARQTQTWVAQQLQIPSEHVAVASTGVIGEYLPMDKIKTGTEHIKDANFATPGAFNEA
ILTTDTCTKHIAVSLKIDGKTVTIGGSTKGSGMIHPNMATMLAFITTDASIESNTLHQLLKSSTDHTFNMITVDGDTSTN
DMVLVMANHQVEHQILSQDHPQWETFVDAFNFVCTFLAKAIARDGEGATKLISVNVSGAKSISDARKIGKTIVSSNLVKS
AIFGEDANFGRIITAIGYSGCEIDPNCTYVQLNQIPVVDKGMAVLFDEQAMSNTLTHENVTIDVQLGLGNAAATAYGCDL
SYDYVRINASYRT

Sequences:

>Translated_413_residues
MKHQETTSQQYNFSIIKHGDISTPQGFTAGGMHIGLRANKKDFGWIYSSSLASAAAVYTLNQFKAAPLIVTEDTLQKSKG
KLQALVVNSANANSCTGQQGIDDARQTQTWVAQQLQIPSEHVAVASTGVIGEYLPMDKIKTGTEHIKDANFATPGAFNEA
ILTTDTCTKHIAVSLKIDGKTVTIGGSTKGSGMIHPNMATMLAFITTDASIESNTLHQLLKSSTDHTFNMITVDGDTSTN
DMVLVMANHQVEHQILSQDHPQWETFVDAFNFVCTFLAKAIARDGEGATKLISVNVSGAKSISDARKIGKTIVSSNLVKS
AIFGEDANFGRIITAIGYSGCEIDPNCTYVQLNQIPVVDKGMAVLFDEQAMSNTLTHENVTIDVQLGLGNAAATAYGCDL
SYDYVRINASYRT
>Mature_413_residues
MKHQETTSQQYNFSIIKHGDISTPQGFTAGGMHIGLRANKKDFGWIYSSSLASAAAVYTLNQFKAAPLIVTEDTLQKSKG
KLQALVVNSANANSCTGQQGIDDARQTQTWVAQQLQIPSEHVAVASTGVIGEYLPMDKIKTGTEHIKDANFATPGAFNEA
ILTTDTCTKHIAVSLKIDGKTVTIGGSTKGSGMIHPNMATMLAFITTDASIESNTLHQLLKSSTDHTFNMITVDGDTSTN
DMVLVMANHQVEHQILSQDHPQWETFVDAFNFVCTFLAKAIARDGEGATKLISVNVSGAKSISDARKIGKTIVSSNLVKS
AIFGEDANFGRIITAIGYSGCEIDPNCTYVQLNQIPVVDKGMAVLFDEQAMSNTLTHENVTIDVQLGLGNAAATAYGCDL
SYDYVRINASYRT

Specific function: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis:the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate

COG id: COG1364

COG function: function code E; N-acetylglutamate synthase (N-acetylornithine aminotransferase)

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArgJ family

Homologues:

Organism=Saccharomyces cerevisiae, GI6323707, Length=430, Percent_Identity=38.3720930232558, Blast_Score=251, Evalue=1e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGJ_STAAC (Q5HJJ0)

Other databases:

- EMBL:   CP000046
- RefSeq:   YP_185067.1
- ProteinModelPortal:   Q5HJJ0
- SMR:   Q5HJJ0
- STRING:   Q5HJJ0
- EnsemblBacteria:   EBSTAT00000009974
- GeneID:   3236042
- GenomeReviews:   CP000046_GR
- KEGG:   sac:SACOL0168
- TIGR:   SACOL0168
- eggNOG:   COG1364
- GeneTree:   EBGT00050000024669
- HOGENOM:   HBG284202
- OMA:   QNRFCAA
- ProtClustDB:   PRK05388
- BioCyc:   SAUR93062:SACOL0168-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01106
- InterPro:   IPR002813
- InterPro:   IPR016117
- PANTHER:   PTHR23100
- TIGRFAMs:   TIGR00120

Pfam domain/function: PF01960 ArgJ; SSF56266 Pept_S58_DmpA/Arg_biosyn_ArgJ

EC number: =2.3.1.35; =2.3.1.1

Molecular weight: Translated: 44401; Mature: 44401

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHQETTSQQYNFSIIKHGDISTPQGFTAGGMHIGLRANKKDFGWIYSSSLASAAAVYTL
CCCCCCCCCCEEEEEEECCCCCCCCCCCCCCEEEEEEECCCCCCEEEHHHHHHHHHEEEH
NQFKAAPLIVTEDTLQKSKGKLQALVVNSANANSCTGQQGIDDARQTQTWVAQQLQIPSE
HHCCCCCEEEEHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCH
HVAVASTGVIGEYLPMDKIKTGTEHIKDANFATPGAFNEAILTTDTCTKHIAVSLKIDGK
HEEEEECCCCCCCCCHHHHCCCHHHHCCCCCCCCCCCCCEEEEECCCCEEEEEEEEECCE
TVTIGGSTKGSGMIHPNMATMLAFITTDASIESNTLHQLLKSSTDHTFNMITVDGDTSTN
EEEECCCCCCCCEECCCHHHEEEEEECCCCCCHHHHHHHHHCCCCCEEEEEEECCCCCCC
DMVLVMANHQVEHQILSQDHPQWETFVDAFNFVCTFLAKAIARDGEGATKLISVNVSGAK
CEEEEEECCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCH
SISDARKIGKTIVSSNLVKSAIFGEDANFGRIITAIGYSGCEIDPNCTYVQLNQIPVVDK
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCEECCCCCEEEECCCCEECC
GMAVLFDEQAMSNTLTHENVTIDVQLGLGNAAATAYGCDLSYDYVRINASYRT
CEEEEEECHHHHCCCCCCCEEEEEEECCCCCHHEEECCCCEEEEEEEEEECCC
>Mature Secondary Structure
MKHQETTSQQYNFSIIKHGDISTPQGFTAGGMHIGLRANKKDFGWIYSSSLASAAAVYTL
CCCCCCCCCCEEEEEEECCCCCCCCCCCCCCEEEEEEECCCCCCEEEHHHHHHHHHEEEH
NQFKAAPLIVTEDTLQKSKGKLQALVVNSANANSCTGQQGIDDARQTQTWVAQQLQIPSE
HHCCCCCEEEEHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCH
HVAVASTGVIGEYLPMDKIKTGTEHIKDANFATPGAFNEAILTTDTCTKHIAVSLKIDGK
HEEEEECCCCCCCCCHHHHCCCHHHHCCCCCCCCCCCCCEEEEECCCCEEEEEEEEECCE
TVTIGGSTKGSGMIHPNMATMLAFITTDASIESNTLHQLLKSSTDHTFNMITVDGDTSTN
EEEECCCCCCCCEECCCHHHEEEEEECCCCCCHHHHHHHHHCCCCCEEEEEEECCCCCCC
DMVLVMANHQVEHQILSQDHPQWETFVDAFNFVCTFLAKAIARDGEGATKLISVNVSGAK
CEEEEEECCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCH
SISDARKIGKTIVSSNLVKSAIFGEDANFGRIITAIGYSGCEIDPNCTYVQLNQIPVVDK
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCEECCCCCEEEECCCCEECC
GMAVLFDEQAMSNTLTHENVTIDVQLGLGNAAATAYGCDLSYDYVRINASYRT
CEEEEEECHHHHCCCCCCCEEEEEEECCCCCHHEEECCCCEEEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA