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The map label for this gene is gntK [H]

Identifier: 57651013

GI number: 57651013

Start: 2574439

End: 2575992

Strand: Reverse

Name: gntK [H]

Synonym: SACOL2515

Alternate gene names: 57651013

Gene position: 2575992-2574439 (Counterclockwise)

Preceding gene: 57651014

Following gene: 57651012

Centisome position: 91.69

GC content: 37.71

Gene sequence:

>1554_bases
ATGAAATATATGATTGGTGTCGACATTGGAACGACGAGTACCAAGTCAGTCTTATATGATGAAAATGGAACTTTTATCAT
GAAACATCAAATAGGCTATGATTTACACACACCAAACGTTGATGTCTCAGAAGAAAACCCAGATGAATTATTTGATGCAG
TACTAATGACTATTAAATATGTTATGAGAGAATCCAAAGTTAATAAAGACGACATTAAGTTTGTGTCATTTAGTGCGCAA
ATGCATAGCTTGATTGCGATGGATCAGCAACATCAAAGATTAACAAATAATATTACTTGGGCAGATAACCGCGCTGCAAA
ATATGCAACAGTAATAAATGAAGTGCATGATGGCAATGCGATTTACCAGCGAACAGGCACACCGATTCATCCTATGTCGC
CATTAGCGAAGATTTTTTGGATGAAACATGAATGGCAAGATGTATTTCAACGTACTGCTAAGTTTGCAGATATTAAAACA
TACATTTTCTATCATTTATTTGATACATATATCATTGATTATTCAATGGCTTCCGCAACAGGGATGTTTAATTTAGAAAC
ATTAGATTGGGATGTTGAGGCATTAGAACTGCTGGGTATTTCCAAGGAAATGTTGCCGGAATTAGTTCCAACAACGTATG
TGATGAAAGGTATGAAAGAACGTTATGCAACATTAATGGGGCTTAATAAAGATACACCGTTTGTTATTGGTGCGAGTGAT
GGGGTCCTTTCTAATTTAGGTGTCAATAGTGTTGGTAAAGGAGAAGTTGCTGTCACAATCGGTACATCTGGGGCGATTCG
TACTGTGATAGATAAACCGCGTACTGATTACAAAGGTAGAATATTTTGTTATGTCTTAACAGAGGACCACTACGTCATCG
GAGGTCCTGTAAATAATGGTGGTGTCGTATTGAGATGGTTGCGCGACGAGTTGCTAGCGAGTGAAGTCGAAACTGCGAAA
CGTCTCGGTGTTGATCCTTATGATGTCTTAACTCAAATTGCAAAGCGTGTTAAACCAGGTGCAGATGGTTTAATATTCCA
TCCCTATTTAGCAGGAGAACGTGCGCCGCTTTGGAACGCAAATGCAAGAGGTTCATTCTTCGGTTTAACTTTATCTCATA
AAAAAGAACATATGATTCGCGCTGCATTAGAAGGTGTTCTTTACAATTTGTATACCGTCTATCTTGCGCTTATTGAAGTA
ATGAATGAAACACCTAAGATGATAAAAGCAACAGGTGGTTTTGCGAAAAGTGAAGTATGGCGTCAAATGATGTCAGATAT
ATTTGACACAGAGTTAGTGGTTCCTGAAAGTTATGAAAGTTCATGCTTAGGTGCCTGCGTGCTCGGACTTAAAGCTGTAG
GTGACATTGAAGATTTTTCAATCGTTTCATCGATGGTCGGTGCCACAAACAATCATACGCCGATTGAAGAAAATGTCACT
GTTTACCAAGAGATCGTATCCATTTTTATCAATTTAAGTCGTTCTTTAACAGAGAATTATGAACAAATTGCAGATTTTCA
ACGCCAACATATCGCTGAAAATAAAACACAATAA

Upstream 100 bases:

>100_bases
GTCAAATTTTGAAAGAAGCGTTTCATTTAAATTTCGACGATGTTGGTAAAGATATTGAAGGATTTTGGTTGAATTAAAAT
GAAAGAAAGAAGGATTTATC

Downstream 100 bases:

>100_bases
ATACGTCACTCAAGCATCTTAGATAAAGTTGTTGTGCCATGACTACTATATATTATGTGGAATACGTGCGCGACGACGGT
GTTACATTCTATTGAAAAGA

Product: gluconokinase

Products: NA

Alternate protein names: Gluconate kinase [H]

Number of amino acids: Translated: 517; Mature: 517

Protein sequence:

>517_residues
MKYMIGVDIGTTSTKSVLYDENGTFIMKHQIGYDLHTPNVDVSEENPDELFDAVLMTIKYVMRESKVNKDDIKFVSFSAQ
MHSLIAMDQQHQRLTNNITWADNRAAKYATVINEVHDGNAIYQRTGTPIHPMSPLAKIFWMKHEWQDVFQRTAKFADIKT
YIFYHLFDTYIIDYSMASATGMFNLETLDWDVEALELLGISKEMLPELVPTTYVMKGMKERYATLMGLNKDTPFVIGASD
GVLSNLGVNSVGKGEVAVTIGTSGAIRTVIDKPRTDYKGRIFCYVLTEDHYVIGGPVNNGGVVLRWLRDELLASEVETAK
RLGVDPYDVLTQIAKRVKPGADGLIFHPYLAGERAPLWNANARGSFFGLTLSHKKEHMIRAALEGVLYNLYTVYLALIEV
MNETPKMIKATGGFAKSEVWRQMMSDIFDTELVVPESYESSCLGACVLGLKAVGDIEDFSIVSSMVGATNNHTPIEENVT
VYQEIVSIFINLSRSLTENYEQIADFQRQHIAENKTQ

Sequences:

>Translated_517_residues
MKYMIGVDIGTTSTKSVLYDENGTFIMKHQIGYDLHTPNVDVSEENPDELFDAVLMTIKYVMRESKVNKDDIKFVSFSAQ
MHSLIAMDQQHQRLTNNITWADNRAAKYATVINEVHDGNAIYQRTGTPIHPMSPLAKIFWMKHEWQDVFQRTAKFADIKT
YIFYHLFDTYIIDYSMASATGMFNLETLDWDVEALELLGISKEMLPELVPTTYVMKGMKERYATLMGLNKDTPFVIGASD
GVLSNLGVNSVGKGEVAVTIGTSGAIRTVIDKPRTDYKGRIFCYVLTEDHYVIGGPVNNGGVVLRWLRDELLASEVETAK
RLGVDPYDVLTQIAKRVKPGADGLIFHPYLAGERAPLWNANARGSFFGLTLSHKKEHMIRAALEGVLYNLYTVYLALIEV
MNETPKMIKATGGFAKSEVWRQMMSDIFDTELVVPESYESSCLGACVLGLKAVGDIEDFSIVSSMVGATNNHTPIEENVT
VYQEIVSIFINLSRSLTENYEQIADFQRQHIAENKTQ
>Mature_517_residues
MKYMIGVDIGTTSTKSVLYDENGTFIMKHQIGYDLHTPNVDVSEENPDELFDAVLMTIKYVMRESKVNKDDIKFVSFSAQ
MHSLIAMDQQHQRLTNNITWADNRAAKYATVINEVHDGNAIYQRTGTPIHPMSPLAKIFWMKHEWQDVFQRTAKFADIKT
YIFYHLFDTYIIDYSMASATGMFNLETLDWDVEALELLGISKEMLPELVPTTYVMKGMKERYATLMGLNKDTPFVIGASD
GVLSNLGVNSVGKGEVAVTIGTSGAIRTVIDKPRTDYKGRIFCYVLTEDHYVIGGPVNNGGVVLRWLRDELLASEVETAK
RLGVDPYDVLTQIAKRVKPGADGLIFHPYLAGERAPLWNANARGSFFGLTLSHKKEHMIRAALEGVLYNLYTVYLALIEV
MNETPKMIKATGGFAKSEVWRQMMSDIFDTELVVPESYESSCLGACVLGLKAVGDIEDFSIVSSMVGATNNHTPIEENVT
VYQEIVSIFINLSRSLTENYEQIADFQRQHIAENKTQ

Specific function: Unknown

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Homo sapiens, GI42794763, Length=459, Percent_Identity=24.400871459695, Blast_Score=119, Evalue=5e-27,
Organism=Homo sapiens, GI189409120, Length=459, Percent_Identity=24.400871459695, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI4504007, Length=459, Percent_Identity=24.400871459695, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI41393575, Length=448, Percent_Identity=23.2142857142857, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI88196792, Length=489, Percent_Identity=23.3128834355828, Blast_Score=103, Evalue=5e-22,
Organism=Escherichia coli, GI1789987, Length=498, Percent_Identity=25.5020080321285, Blast_Score=152, Evalue=4e-38,
Organism=Escherichia coli, GI1790361, Length=465, Percent_Identity=26.6666666666667, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI1787789, Length=503, Percent_Identity=25.0497017892644, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI1790005, Length=517, Percent_Identity=22.8239845261122, Blast_Score=125, Evalue=5e-30,
Organism=Escherichia coli, GI1789168, Length=461, Percent_Identity=20.824295010846, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1789138, Length=516, Percent_Identity=23.2558139534884, Blast_Score=98, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17535599, Length=465, Percent_Identity=24.5161290322581, Blast_Score=119, Evalue=4e-27,
Organism=Saccharomyces cerevisiae, GI6321755, Length=360, Percent_Identity=25.2777777777778, Blast_Score=89, Evalue=1e-18,
Organism=Drosophila melanogaster, GI17864214, Length=487, Percent_Identity=24.8459958932238, Blast_Score=119, Evalue=6e-27,
Organism=Drosophila melanogaster, GI24654573, Length=413, Percent_Identity=24.9394673123487, Blast_Score=113, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24655555, Length=447, Percent_Identity=25.2796420581655, Blast_Score=112, Evalue=6e-25,
Organism=Drosophila melanogaster, GI24655560, Length=447, Percent_Identity=25.2796420581655, Blast_Score=112, Evalue=6e-25,
Organism=Drosophila melanogaster, GI24655570, Length=447, Percent_Identity=25.2796420581655, Blast_Score=112, Evalue=6e-25,
Organism=Drosophila melanogaster, GI24655574, Length=447, Percent_Identity=25.2796420581655, Blast_Score=112, Evalue=6e-25,
Organism=Drosophila melanogaster, GI24655565, Length=447, Percent_Identity=25.2796420581655, Blast_Score=112, Evalue=6e-25,
Organism=Drosophila melanogaster, GI24656367, Length=507, Percent_Identity=22.879684418146, Blast_Score=112, Evalue=8e-25,
Organism=Drosophila melanogaster, GI21357867, Length=518, Percent_Identity=23.1660231660232, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24656372, Length=355, Percent_Identity=24.5070422535211, Blast_Score=91, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR006002 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.12 [H]

Molecular weight: Translated: 58095; Mature: 58095

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: PS00445 FGGY_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYMIGVDIGTTSTKSVLYDENGTFIMKHQIGYDLHTPNVDVSEENPDELFDAVLMTIKY
CCEEEEEECCCCCCCEEEEECCCCEEEEEECCCEECCCCCCCCCCCHHHHHHHHHHHHHH
VMRESKVNKDDIKFVSFSAQMHSLIAMDQQHQRLTNNITWADNRAAKYATVINEVHDGNA
HHHHCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCE
IYQRTGTPIHPMSPLAKIFWMKHEWQDVFQRTAKFADIKTYIFYHLFDTYIIDYSMASAT
EEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GMFNLETLDWDVEALELLGISKEMLPELVPTTYVMKGMKERYATLMGLNKDTPFVIGASD
CCEEEEECCCCHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCC
GVLSNLGVNSVGKGEVAVTIGTSGAIRTVIDKPRTDYKGRIFCYVLTEDHYVIGGPVNNG
CHHHHCCCCCCCCCCEEEEECCCCCHHHHHCCCCCCCCCEEEEEEEECCCEEEECCCCCC
GVVLRWLRDELLASEVETAKRLGVDPYDVLTQIAKRVKPGADGLIFHPYLAGERAPLWNA
CEEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCC
NARGSFFGLTLSHKKEHMIRAALEGVLYNLYTVYLALIEVMNETPKMIKATGGFAKSEVW
CCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEECCCCHHHHHH
RQMMSDIFDTELVVPESYESSCLGACVLGLKAVGDIEDFSIVSSMVGATNNHTPIEENVT
HHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCHH
VYQEIVSIFINLSRSLTENYEQIADFQRQHIAENKTQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKYMIGVDIGTTSTKSVLYDENGTFIMKHQIGYDLHTPNVDVSEENPDELFDAVLMTIKY
CCEEEEEECCCCCCCEEEEECCCCEEEEEECCCEECCCCCCCCCCCHHHHHHHHHHHHHH
VMRESKVNKDDIKFVSFSAQMHSLIAMDQQHQRLTNNITWADNRAAKYATVINEVHDGNA
HHHHCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCE
IYQRTGTPIHPMSPLAKIFWMKHEWQDVFQRTAKFADIKTYIFYHLFDTYIIDYSMASAT
EEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GMFNLETLDWDVEALELLGISKEMLPELVPTTYVMKGMKERYATLMGLNKDTPFVIGASD
CCEEEEECCCCHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCC
GVLSNLGVNSVGKGEVAVTIGTSGAIRTVIDKPRTDYKGRIFCYVLTEDHYVIGGPVNNG
CHHHHCCCCCCCCCCEEEEECCCCCHHHHHCCCCCCCCCEEEEEEEECCCEEEECCCCCC
GVVLRWLRDELLASEVETAKRLGVDPYDVLTQIAKRVKPGADGLIFHPYLAGERAPLWNA
CEEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCC
NARGSFFGLTLSHKKEHMIRAALEGVLYNLYTVYLALIEVMNETPKMIKATGGFAKSEVW
CCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEECCCCHHHHHH
RQMMSDIFDTELVVPESYESSCLGACVLGLKAVGDIEDFSIVSSMVGATNNHTPIEENVT
HHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCHH
VYQEIVSIFINLSRSLTENYEQIADFQRQHIAENKTQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3020045; 7584049; 9384377 [H]