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The map label for this gene is rpiA

Identifier: 57650878

GI number: 57650878

Start: 2392091

End: 2392777

Strand: Reverse

Name: rpiA

Synonym: SACOL2329

Alternate gene names: 57650878

Gene position: 2392777-2392091 (Counterclockwise)

Preceding gene: 57650880

Following gene: 57650876

Centisome position: 85.17

GC content: 33.48

Gene sequence:

>687_bases
ATGAAAGATGTCAAAGCACTCAAGTTAATGACATTAAATGATGTTTTAAGTCAAATCAATGGTGACATGACGCTGGGAAT
TGGTACAGGAAGTACAATGGAATTACTCTTACCTCAAATGGCGCAACTAATTAAAGAACGTGGTTACAATATTACAGGTG
TATGCACTTCTAATAAAATTGCATTTTTAGCAAAAGAATTAGGTATTAAAATATGTGAAATCAATGATGTTGATCATATC
GACTTAGCAATTGATGGTGCTGATGAAGTAGATCCATCTTTAAATATAATTAAAGGTGGCGGTGGTGCGCTGTTCAGAGA
GAAAGTTATAGATGAAATGGCATCGCGTTTTGTTGTGGTTGTCGATGAAACGAAAATAGTTCAATACTTAGGTGAGACGT
TTAAGTTACCAGTAGAGGTGGATAAATTTAACTGGTATCAGATATTACGTAAAATTGAATCATACGCTGATATAAAAGTA
GAACGTCGTGTAAACGAAGATGTCGCATTTATAACTGATAATGGCAATTATATTTTAGATTGTAAGTTACCAAAAGGAAT
TGACCCATATAAGTTCCATGAGTATTTAATTCATCTGACAGGTGTGTTTGAGACAGGATACTTCTTAGATATGGCAGATC
AAGTTATTGTAGGCACTCAAGAGGGTGTTAAAATTTTAGAAAAATAA

Upstream 100 bases:

>100_bases
GATATGTTTAAAAAAATGTTAGAAATAAGGGTATGTTAATTTATACGAGTCATGTAAAATATGAATTGAATAGATTACAT
AAATATGGGAGGCTACCTTC

Downstream 100 bases:

>100_bases
TATATAGTATAGAAAAGCGCTTGCTAGCATCATCTTTTTAAGAGGTACTAGCAAGCGCTTTGTTATTATTTGTTTTTATC
TGAAGATTGTTCTTCAGTTT

Product: ribose-5-phosphate isomerase A

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI

Number of amino acids: Translated: 228; Mature: 228

Protein sequence:

>228_residues
MKDVKALKLMTLNDVLSQINGDMTLGIGTGSTMELLLPQMAQLIKERGYNITGVCTSNKIAFLAKELGIKICEINDVDHI
DLAIDGADEVDPSLNIIKGGGGALFREKVIDEMASRFVVVVDETKIVQYLGETFKLPVEVDKFNWYQILRKIESYADIKV
ERRVNEDVAFITDNGNYILDCKLPKGIDPYKFHEYLIHLTGVFETGYFLDMADQVIVGTQEGVKILEK

Sequences:

>Translated_228_residues
MKDVKALKLMTLNDVLSQINGDMTLGIGTGSTMELLLPQMAQLIKERGYNITGVCTSNKIAFLAKELGIKICEINDVDHI
DLAIDGADEVDPSLNIIKGGGGALFREKVIDEMASRFVVVVDETKIVQYLGETFKLPVEVDKFNWYQILRKIESYADIKV
ERRVNEDVAFITDNGNYILDCKLPKGIDPYKFHEYLIHLTGVFETGYFLDMADQVIVGTQEGVKILEK
>Mature_228_residues
MKDVKALKLMTLNDVLSQINGDMTLGIGTGSTMELLLPQMAQLIKERGYNITGVCTSNKIAFLAKELGIKICEINDVDHI
DLAIDGADEVDPSLNIIKGGGGALFREKVIDEMASRFVVVVDETKIVQYLGETFKLPVEVDKFNWYQILRKIESYADIKV
ERRVNEDVAFITDNGNYILDCKLPKGIDPYKFHEYLIHLTGVFETGYFLDMADQVIVGTQEGVKILEK

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family

Homologues:

Organism=Homo sapiens, GI94536842, Length=232, Percent_Identity=35.7758620689655, Blast_Score=129, Evalue=2e-30,
Organism=Escherichia coli, GI1789280, Length=205, Percent_Identity=34.1463414634146, Blast_Score=111, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17551758, Length=215, Percent_Identity=31.6279069767442, Blast_Score=100, Evalue=5e-22,
Organism=Saccharomyces cerevisiae, GI6324669, Length=217, Percent_Identity=31.7972350230415, Blast_Score=100, Evalue=2e-22,
Organism=Drosophila melanogaster, GI281364072, Length=213, Percent_Identity=34.2723004694836, Blast_Score=102, Evalue=3e-22,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): RPIA_STAAC (Q5HDM1)

Other databases:

- EMBL:   CP000046
- RefSeq:   YP_187136.1
- ProteinModelPortal:   Q5HDM1
- SMR:   Q5HDM1
- STRING:   Q5HDM1
- EnsemblBacteria:   EBSTAT00000008670
- GeneID:   3238444
- GenomeReviews:   CP000046_GR
- KEGG:   sac:SACOL2329
- TIGR:   SACOL2329
- eggNOG:   COG0120
- GeneTree:   EBGT00050000025309
- HOGENOM:   HBG515603
- OMA:   MVVIADA
- ProtClustDB:   PRK13978
- BioCyc:   SAUR93062:SACOL2329-MONOMER
- HAMAP:   MF_00170
- InterPro:   IPR004788
- InterPro:   IPR020672
- PANTHER:   PTHR11934
- TIGRFAMs:   TIGR00021

Pfam domain/function: PF06026 Rib_5-P_isom_A

EC number: =5.3.1.6

Molecular weight: Translated: 25541; Mature: 25541

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDVKALKLMTLNDVLSQINGDMTLGIGTGSTMELLLPQMAQLIKERGYNITGVCTSNKI
CCCCHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCH
AFLAKELGIKICEINDVDHIDLAIDGADEVDPSLNIIKGGGGALFREKVIDEMASRFVVV
HHHHHHHCEEEEEECCCCEEEEEECCCCCCCCCCEEEECCCCHHHHHHHHHHHHCCEEEE
VDETKIVQYLGETFKLPVEVDKFNWYQILRKIESYADIKVERRVNEDVAFITDNGNYILD
EECHHHHHHHHHHEECCEEECCCCHHHHHHHHHHHHCEEEEECCCCCEEEEECCCCEEEE
CKLPKGIDPYKFHEYLIHLTGVFETGYFLDMADQVIVGTQEGVKILEK
EECCCCCCHHHHHHHHHHHHHHHCCCEEEECCCEEEEECHHHHHHHCC
>Mature Secondary Structure
MKDVKALKLMTLNDVLSQINGDMTLGIGTGSTMELLLPQMAQLIKERGYNITGVCTSNKI
CCCCHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCH
AFLAKELGIKICEINDVDHIDLAIDGADEVDPSLNIIKGGGGALFREKVIDEMASRFVVV
HHHHHHHCEEEEEECCCCEEEEEECCCCCCCCCCEEEECCCCHHHHHHHHHHHHCCEEEE
VDETKIVQYLGETFKLPVEVDKFNWYQILRKIESYADIKVERRVNEDVAFITDNGNYILD
EECHHHHHHHHHHEECCEEECCCCHHHHHHHHHHHHCEEEEECCCCCEEEEECCCCEEEE
CKLPKGIDPYKFHEYLIHLTGVFETGYFLDMADQVIVGTQEGVKILEK
EECCCCCCHHHHHHHHHHHHHHHCCCEEEECCCEEEEECHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA