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The map label for this gene is clpB [H]

Identifier: 57650799

GI number: 57650799

Start: 2284801

End: 2285937

Strand: Reverse

Name: clpB [H]

Synonym: SACOL2203

Alternate gene names: 57650799

Gene position: 2285937-2284801 (Counterclockwise)

Preceding gene: 57650800

Following gene: 57650798

Centisome position: 81.37

GC content: 25.95

Gene sequence:

>1137_bases
ATGGAAATTCATGTTTATACGGGACCGCTTTGTGGATTTAATGAATATATTAATTCTGAAGTTAAAGAATATCACCGCTT
CATGGAATTAATCAGAGAATACAATATCATAGTGCGAGCAAGTGATACATTTGGAACTCATGATGTTGATGGTATTTTTG
ATACTGAGATAGAAAATCTTGTGATATTTTCAAACGACTTTGCTTCTGTAACAACTCATGTTATTACTAATTTTATAAAT
ATCGTTACTTTAGGTAGAAATATTAAGAAAATCTATATTCAGAATCCTCCAAAAAGAGTATTTCAATCACTAAATAGTTT
TCACGATTCTGAAATAATAGAAATAAACTATGAATATACAACATTAAAAAAAGATGATGTAATAAATTTTTATAAAGAGC
AGATGGCTGGTTCTAAAATAATAGGTCAAACAGACGCTAAAAAACAAATGAGCATAGATTTATATAAACATACTTCCTTA
GAAAATAATAAACCGACCGTAATGCTTTACTATGGTCCATCAGGTGTTGGAAAAACAGAATTAGCCAAAGAAATAGCAAA
AAAATATAAAGGTAATATCACTAGAATACAATTTTCTATGATGCAGAATGATGAATCTTTTAATTATATCTTTGGAGATG
AACATGCCAAAGTATCATTGTCAAAAGATTTAGTAGATCGTGAAACTAATGTTGTTTTAATTGATGAATTTGATAAGGTA
TTACCAATCTATTACAATGTTTTCTATCAAATGTTTGATGAAGGTATTATTGAAGATGCCAATTATAAAGTAGACGTTTC
AAATTGTATTTTCATTCTAACATCTAATTTTAATAGTATTGAAGAAGCAATAGTTAATATTGGAGAACCGGTATTTTCTA
GAATAGATTCCTGTATTAAATTTTTATATTTAACACAGGAAGAAAAGCAGAAAGTAATAGAAAATAAATTAAATGAAATA
CTATCATCTCTAAATGAAAAAGAAAAAAGAATAGTTACCGCATATAACTTGTTAGAGAAATATAAAGAGACAGAAATAGA
TATCGATAACATTAGGTATTTAAAGAAAATAATAACAAATGATATTTATACAATAATTTTTGAAGATGAATTATTTAATA
CGGATATTATAGATTAA

Upstream 100 bases:

>100_bases
CAAACCTAGTGGAATTGGAAAGTTTAAGGGAATTAGATCAGAAGCAACTAAAGAAGATAAATATCAAGTGTATGATGTTA
TTCTTGCAGGAGTGAAATAA

Downstream 100 bases:

>100_bases
TTTATATGCTTTATATTTTTTTAGTATAAGTTATATATTAATAAAGTACTATCTATGTAAGGTTGTAAGTAGTATAAGTT
AAGAGTTTAATAATTTTAAA

Product: ClpA-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 378; Mature: 378

Protein sequence:

>378_residues
MEIHVYTGPLCGFNEYINSEVKEYHRFMELIREYNIIVRASDTFGTHDVDGIFDTEIENLVIFSNDFASVTTHVITNFIN
IVTLGRNIKKIYIQNPPKRVFQSLNSFHDSEIIEINYEYTTLKKDDVINFYKEQMAGSKIIGQTDAKKQMSIDLYKHTSL
ENNKPTVMLYYGPSGVGKTELAKEIAKKYKGNITRIQFSMMQNDESFNYIFGDEHAKVSLSKDLVDRETNVVLIDEFDKV
LPIYYNVFYQMFDEGIIEDANYKVDVSNCIFILTSNFNSIEEAIVNIGEPVFSRIDSCIKFLYLTQEEKQKVIENKLNEI
LSSLNEKEKRIVTAYNLLEKYKETEIDIDNIRYLKKIITNDIYTIIFEDELFNTDIID

Sequences:

>Translated_378_residues
MEIHVYTGPLCGFNEYINSEVKEYHRFMELIREYNIIVRASDTFGTHDVDGIFDTEIENLVIFSNDFASVTTHVITNFIN
IVTLGRNIKKIYIQNPPKRVFQSLNSFHDSEIIEINYEYTTLKKDDVINFYKEQMAGSKIIGQTDAKKQMSIDLYKHTSL
ENNKPTVMLYYGPSGVGKTELAKEIAKKYKGNITRIQFSMMQNDESFNYIFGDEHAKVSLSKDLVDRETNVVLIDEFDKV
LPIYYNVFYQMFDEGIIEDANYKVDVSNCIFILTSNFNSIEEAIVNIGEPVFSRIDSCIKFLYLTQEEKQKVIENKLNEI
LSSLNEKEKRIVTAYNLLEKYKETEIDIDNIRYLKKIITNDIYTIIFEDELFNTDIID
>Mature_378_residues
MEIHVYTGPLCGFNEYINSEVKEYHRFMELIREYNIIVRASDTFGTHDVDGIFDTEIENLVIFSNDFASVTTHVITNFIN
IVTLGRNIKKIYIQNPPKRVFQSLNSFHDSEIIEINYEYTTLKKDDVINFYKEQMAGSKIIGQTDAKKQMSIDLYKHTSL
ENNKPTVMLYYGPSGVGKTELAKEIAKKYKGNITRIQFSMMQNDESFNYIFGDEHAKVSLSKDLVDRETNVVLIDEFDKV
LPIYYNVFYQMFDEGIIEDANYKVDVSNCIFILTSNFNSIEEAIVNIGEPVFSRIDSCIKFLYLTQEEKQKVIENKLNEI
LSSLNEKEKRIVTAYNLLEKYKETEIDIDNIRYLKKIITNDIYTIIFEDELFNTDIID

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the clpA/clpB family [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=165, Percent_Identity=33.9393939393939, Blast_Score=73, Evalue=4e-13,
Organism=Escherichia coli, GI1788943, Length=316, Percent_Identity=24.6835443037975, Blast_Score=74, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6323002, Length=269, Percent_Identity=28.2527881040892, Blast_Score=75, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6320464, Length=248, Percent_Identity=25.8064516129032, Blast_Score=70, Evalue=4e-13,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR017730
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small [H]

EC number: NA

Molecular weight: Translated: 44101; Mature: 44101

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIHVYTGPLCGFNEYINSEVKEYHRFMELIREYNIIVRASDTFGTHDVDGIFDTEIENL
CEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCEE
VIFSNDFASVTTHVITNFINIVTLGRNIKKIYIQNPPKRVFQSLNSFHDSEIIEINYEYT
EEEECCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHCCCCCCEEEEEEEEE
TLKKDDVINFYKEQMAGSKIIGQTDAKKQMSIDLYKHTSLENNKPTVMLYYGPSGVGKTE
ECCCHHHHHHHHHHHCCCCEECCCCCCHHHEEEEEEECCCCCCCCEEEEEECCCCCCHHH
LAKEIAKKYKGNITRIQFSMMQNDESFNYIFGDEHAKVSLSKDLVDRETNVVLIDEFDKV
HHHHHHHHHCCCEEEEEEEEECCCCCCCEEECCCCCEEEHHHHHHCCCCCEEEEECCCHH
LPIYYNVFYQMFDEGIIEDANYKVDVSNCIFILTSNFNSIEEAIVNIGEPVFSRIDSCIK
HHHHHHHHHHHHHCCCCCCCCEEEECCCEEEEEECCCCHHHHHHHHCCCHHHHHHHHHHH
FLYLTQEEKQKVIENKLNEILSSLNEKEKRIVTAYNLLEKYKETEIDIDNIRYLKKIITN
HHHCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCC
DIYTIIFEDELFNTDIID
CEEEEEEECCCCCCCCCC
>Mature Secondary Structure
MEIHVYTGPLCGFNEYINSEVKEYHRFMELIREYNIIVRASDTFGTHDVDGIFDTEIENL
CEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCEE
VIFSNDFASVTTHVITNFINIVTLGRNIKKIYIQNPPKRVFQSLNSFHDSEIIEINYEYT
EEEECCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHCCCCCCEEEEEEEEE
TLKKDDVINFYKEQMAGSKIIGQTDAKKQMSIDLYKHTSLENNKPTVMLYYGPSGVGKTE
ECCCHHHHHHHHHHHCCCCEECCCCCCHHHEEEEEEECCCCCCCCEEEEEECCCCCCHHH
LAKEIAKKYKGNITRIQFSMMQNDESFNYIFGDEHAKVSLSKDLVDRETNVVLIDEFDKV
HHHHHHHHHCCCEEEEEEEEECCCCCCCEEECCCCCEEEHHHHHHCCCCCEEEEECCCHH
LPIYYNVFYQMFDEGIIEDANYKVDVSNCIFILTSNFNSIEEAIVNIGEPVFSRIDSCIK
HHHHHHHHHHHHHCCCCCCCCEEEECCCEEEEEECCCCHHHHHHHHCCCHHHHHHHHHHH
FLYLTQEEKQKVIENKLNEILSSLNEKEKRIVTAYNLLEKYKETEIDIDNIRYLKKIITN
HHHCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCC
DIYTIIFEDELFNTDIID
CEEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA