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The map label for this gene is adhR [H]

Identifier: 57650789

GI number: 57650789

Start: 2273402

End: 2273818

Strand: Reverse

Name: adhR [H]

Synonym: SACOL2193

Alternate gene names: 57650789

Gene position: 2273818-2273402 (Counterclockwise)

Preceding gene: 57650791

Following gene: 57650788

Centisome position: 80.94

GC content: 29.98

Gene sequence:

>417_bases
ATGAAAACTAAAGAAGTCGTAGCGCTCATGAATATATCTCAAGACACTTTAAGATATTATGAAAAGGTTGGTGTGATTCC
ACCAGTTAATCGAGATGAAAATGGATATAGAATATATAATGATAGTGATTTAAATTGGATTTATTTAGTGAAAAATTTGC
GAAATGCAGGCGTCAGTATTGAATCGCTTATCGAATTTTGCAGGTTAGCGCAGCTTCCTAAAAATGAAAATATTCAAGCA
CAGCAAAAGCAAATTTTAAATAAGCAACTCGAAGAATTAAATGAAAACTTAAAGACAATTCATGATGCGAGAGATTTACT
ACAATATAAAATTGATAATTATGATAATCATATTGCTAAAATCAATGCTAGTGATAATTATGATGACAATGTTGAACGTC
TTTGGGAGAGAAAGTAA

Upstream 100 bases:

>100_bases
TTAAATTTGAGTAATAAAATAAGAAGTATTCAAACGAAGATGACAATATATAAAGCAACATTACTTTAGACGACCAAACA
TAACTGAAAGGATAGTCGCA

Downstream 100 bases:

>100_bases
ACCTATGGCTTGCTATAGAGTTCGCTCCATGGTTTATAGTGGACATACAAGATAAAGGAGGTTCATTTTATGAATCATAT
TGAAATAAGTAAAGATGTAA

Product: MerR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 138; Mature: 138

Protein sequence:

>138_residues
MKTKEVVALMNISQDTLRYYEKVGVIPPVNRDENGYRIYNDSDLNWIYLVKNLRNAGVSIESLIEFCRLAQLPKNENIQA
QQKQILNKQLEELNENLKTIHDARDLLQYKIDNYDNHIAKINASDNYDDNVERLWERK

Sequences:

>Translated_138_residues
MKTKEVVALMNISQDTLRYYEKVGVIPPVNRDENGYRIYNDSDLNWIYLVKNLRNAGVSIESLIEFCRLAQLPKNENIQA
QQKQILNKQLEELNENLKTIHDARDLLQYKIDNYDNHIAKINASDNYDDNVERLWERK
>Mature_138_residues
MKTKEVVALMNISQDTLRYYEKVGVIPPVNRDENGYRIYNDSDLNWIYLVKNLRNAGVSIESLIEFCRLAQLPKNENIQA
QQKQILNKQLEELNENLKTIHDARDLLQYKIDNYDNHIAKINASDNYDDNVERLWERK

Specific function: Transcriptional regulator involved in the response to aldehyde stress. Binds to the promoter region of the adhA-yraA operon, the yraC and its own promoter region; binding is unchanged in the presence of aldehydes [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR015358 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind [H]

EC number: NA

Molecular weight: Translated: 16341; Mature: 16341

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTKEVVALMNISQDTLRYYEKVGVIPPVNRDENGYRIYNDSDLNWIYLVKNLRNAGVSI
CCCHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHCCCCH
ESLIEFCRLAQLPKNENIQAQQKQILNKQLEELNENLKTIHDARDLLQYKIDNYDNHIAK
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
INASDNYDDNVERLWERK
ECCCCCCCHHHHHHHCCC
>Mature Secondary Structure
MKTKEVVALMNISQDTLRYYEKVGVIPPVNRDENGYRIYNDSDLNWIYLVKNLRNAGVSI
CCCHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHCCCCH
ESLIEFCRLAQLPKNENIQAQQKQILNKQLEELNENLKTIHDARDLLQYKIDNYDNHIAK
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
INASDNYDDNVERLWERK
ECCCCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9141695; 9384377 [H]