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The map label for this gene is agrB

Identifier: 57650708

GI number: 57650708

Start: 2083138

End: 2083707

Strand: Direct

Name: agrB

Synonym: SACOL2023

Alternate gene names: 57650708

Gene position: 2083138-2083707 (Clockwise)

Preceding gene: 57650706

Following gene: 57650709

Centisome position: 74.15

GC content: 27.19

Gene sequence:

>570_bases
TTGAATTATTTTGATAATAAAATTGACCAGTTTGCCACGTATCTTCAAAAGAGAAATAACTTAGATCATATTCAATTTTT
GCAAGTACGATTAGGGATGCAGGTCTTAGCTAAAAATATAGGTAAATTAATTGTTATGTATACTATTGCCTATATTTTAA
ACATTTTTCTGTTTACGTTAATTACGAATTTAACATTTTATTTAATAAGAAGACATGCACATGGTGCACATGCACCTTCT
TCTTTTTGGTGTTATGTAGAAAGTATTATACTATTTATACTTTTACCTTTAGTAATAGTAAATTTTCATATTAACTTTTT
AATTATGATTATTTTAACAGTTATTTCTTTAGGTGTAATCTCAGTATATGCTCCTGCAGCAACTAAAAAGAAGCCCATTC
CTGTGCGACTTATTAAACGAAAAAAATATTATGCGATTATTGTTAGTTTAACCCTTTTCATTATCACACTTATCATCAAA
GAGCCATTTGCCCAATTCATTCAATTAGGCATCATAATAGAAGCTATTACATTATTACCTATTTTCTTTATTAAGGAGGA
CTTAAAATGA

Upstream 100 bases:

>100_bases
TTACATTTAACAGTTAAGTATTTATTTCCTACAGTTAGGCAATATAATGATAAAAGATTGTACTAAATCGTATAATGACA
GTGAGGAGAGTGGTGTAAAA

Downstream 100 bases:

>100_bases
ATACATTATTTAACTTATTTTTTGATTTTATTACTGGGATTTTAAAAAACATTGGTAACATCGCAGCTTATAGTACTTGT
GACTTCATAATGGATGAAGT

Product: accessory gene regulator protein B

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 189; Mature: 189

Protein sequence:

>189_residues
MNYFDNKIDQFATYLQKRNNLDHIQFLQVRLGMQVLAKNIGKLIVMYTIAYILNIFLFTLITNLTFYLIRRHAHGAHAPS
SFWCYVESIILFILLPLVIVNFHINFLIMIILTVISLGVISVYAPAATKKKPIPVRLIKRKKYYAIIVSLTLFIITLIIK
EPFAQFIQLGIIIEAITLLPIFFIKEDLK

Sequences:

>Translated_189_residues
MNYFDNKIDQFATYLQKRNNLDHIQFLQVRLGMQVLAKNIGKLIVMYTIAYILNIFLFTLITNLTFYLIRRHAHGAHAPS
SFWCYVESIILFILLPLVIVNFHINFLIMIILTVISLGVISVYAPAATKKKPIPVRLIKRKKYYAIIVSLTLFIITLIIK
EPFAQFIQLGIIIEAITLLPIFFIKEDLK
>Mature_189_residues
MNYFDNKIDQFATYLQKRNNLDHIQFLQVRLGMQVLAKNIGKLIVMYTIAYILNIFLFTLITNLTFYLIRRHAHGAHAPS
SFWCYVESIILFILLPLVIVNFHINFLIMIILTVISLGVISVYAPAATKKKPIPVRLIKRKKYYAIIVSLTLFIITLIIK
EPFAQFIQLGIIIEAITLLPIFFIKEDLK

Specific function: Essential for the production of a quorum sensing system signal molecule, the autoinducing peptide (AIP). This quorum sensing system is responsible for the regulation of the expression of virulence factor genes. Involved in the proteolytic processing of Ag

COG id: COG4512

COG function: function code OTK; Membrane protein putatively involved in post-translational modification of the autoinducing quorum-sensing peptide

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AgrB family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AGRB_STAA3 (Q2FF88)

Other databases:

- EMBL:   CP000255
- RefSeq:   YP_494640.1
- STRING:   Q2FF88
- EnsemblBacteria:   EBSTAT00000037251
- GeneID:   3914498
- GenomeReviews:   CP000255_GR
- KEGG:   saa:SAUSA300_1989
- eggNOG:   COG4512
- GeneTree:   EBGT00050000024407
- HOGENOM:   HBG692974
- OMA:   CENITNV
- ProtClustDB:   CLSK885730
- GO:   GO:0009405
- HAMAP:   MF_00784
- InterPro:   IPR006741
- SMART:   SM00793

Pfam domain/function: PF04647 AgrB

EC number: NA

Molecular weight: Translated: 21930; Mature: 21930

Theoretical pI: Translated: 10.33; Mature: 10.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xed89874)-; HASH(0xf49c6b0)-; HASH(0xe25d904)-; HASH(0xb404d24)-; HASH(0xfbb94fc)-;

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYFDNKIDQFATYLQKRNNLDHIQFLQVRLGMQVLAKNIGKLIVMYTIAYILNIFLFTL
CCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ITNLTFYLIRRHAHGAHAPSSFWCYVESIILFILLPLVIVNFHINFLIMIILTVISLGVI
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVYAPAATKKKPIPVRLIKRKKYYAIIVSLTLFIITLIIKEPFAQFIQLGIIIEAITLLP
HHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IFFIKEDLK
HHHHHHCCH
>Mature Secondary Structure
MNYFDNKIDQFATYLQKRNNLDHIQFLQVRLGMQVLAKNIGKLIVMYTIAYILNIFLFTL
CCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ITNLTFYLIRRHAHGAHAPSSFWCYVESIILFILLPLVIVNFHINFLIMIILTVISLGVI
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVYAPAATKKKPIPVRLIKRKKYYAIIVSLTLFIITLIIKEPFAQFIQLGIIIEAITLLP
HHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IFFIKEDLK
HHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA