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The map label for this gene is aspS

Identifier: 57650511

GI number: 57650511

Start: 1713268

End: 1715034

Strand: Reverse

Name: aspS

Synonym: SACOL1685

Alternate gene names: 57650511

Gene position: 1715034-1713268 (Counterclockwise)

Preceding gene: 57650512

Following gene: 57650510

Centisome position: 61.05

GC content: 35.6

Gene sequence:

>1767_bases
ATGAGTAAGAGAACAACTTATTGTGGATTAGTTACTGAGGCATTTTTAGGACAAGAAATTACATTAAAAGGATGGGTTAA
CAATCGTCGTGACCTTGGTGGATTGATTTTCGTTGATTTAAGAGATAGAGAAGGAATTGTACAAGTCGTGTTTAATCCTG
CATTTTCAGAAGAGGCATTGAAAATTGCTGAAACAGTACGTTCTGAATATGTTGTAGAAGTTCAAGGTACAGTTACGAAG
CGTGACCCTGAAACAGTTAATCCTAAAATTAAAACTGGCCAAGTTGAAGTACAAGTTACAAATATTAAAGTGATTAATAA
ATCTGAGACACCACCATTTTCTATAAATGAAGAAAATGTTAACGTTGATGAAAATATTCGATTAAAATACCGTTATTTAG
ATTTACGTCGTCAAGAGTTAGCGCAAACATTTAAAATGAGACATCAAATTACACGTTCTATTCGTCAATATTTGGATGAT
GAAGGGTTCTTTGACATCGAAACACCAGTACTAACGAAGTCAACACCTGAGGGTGCACGTGACTATTTAGTACCATCTCG
TGTTCATGATGGTGAATTTTATGCATTACCACAATCACCACAATTATTTAAGCAATTATTGATGATTAGTGGATTTGACA
AATACTACCAAATCGTAAAATGCTTCCGTGACGAAGATTTACGTGCAGATCGTCAACCTGAATTTACACAAGTCGATATT
GAAATGAGTTTTGTAGACCAAGAAGATGTGATGCAAATGGGTGAAGAAATGCTTAAAAAAGTTGTTAAAGAAGTTAAAGG
CGTTGAAATTAATGGCGCTTTCCCACGCATGACATATAAAGAAGCGATGCGTCGCTATGGTTCTGATAAACCAGATACAC
GTTTTGAAATGGAATTAATTGACGTTTCTCAATTAGGACGTGATATGGACTTTAAAGTATTTAAAGATACTGTTGAAAAT
GATGGTGAAATTAAAGCAATTGTCGCTAAAGGTGCAGCTGAACAATATACTCGTAAAGATATGGATGCTTTAACAGAATT
TGTAAACATCTATGGTGCTAAAGGATTAGCGTGGGTTAAAGTTGTGGAAGATGGTTTGACAGGTCCAATTGGACGTTTCT
TTGAAACAGAAAATGTTGAAACATTACTTACATTAACTGGTGCTGAAGCTGGTGACTTAGTAATGTTTGTTGCAGACAAA
CCAAATGTCGTTGCACAAAGTTTAGGTGCATTACGTGTCAAATTAGCTAAAGAATTAGGTTTAATCGATGAAACAAAATT
AAACTTCTTATGGGTGACAGATTGGCCATTATTAGAATATGATGAAGATGCGAAACGTTACGTTGCAGCACATCATCCAT
TTACATCTCCAAAAGAAGCTGATATTGCTAAGCTTGGCACTGCGCCAGAAGAAGCTGAGGCAAATGCTTATGACATAGTA
TTAAATGGTTATGAATTAGGTGGCGGTTCAATCAGAATTCATGATGGTGAGTTACAAGAAAAAATGTTCGAAGTTCTTGG
ATTTACTAAAGAACAAGCACAAGAACAGTTCGGCTTCTTACTAGATGCATTTAAATATGGTGCACCACCACATGGCGGTA
TTGCATTAGGATTAGACCGATTAGTCATGTTATTGACTAATAGAACAAACTTGAGAGATACAATCGCATTCCCTAAAACA
GCATCTGCTACATGTTTATTAACGAATGCGCCTGGTGAAGTTTCTGATAAACAATTAGAAGAACTTTCTTTGCGAATTCG
TCACTAA

Upstream 100 bases:

>100_bases
TAATAAAATCGATGTTAAAAATATGACAACTGGTGAATCTGAAACAATTGAATTAGACGCATTAGTCGAATATTTTAAGA
AGTAGAGAGGGCGTTAAAAT

Downstream 100 bases:

>100_bases
ATTTTAAAAAATCAATAAACTTTGGTTTGTTATAATTTCATTAATTTTAATTATGTGGTAATATAACATCATAAGATAGT
CATCTGAGTTGTTCGTAAGT

Product: aspartyl-tRNA synthetase

Products: NA

Alternate protein names: Aspartate--tRNA ligase; AspRS

Number of amino acids: Translated: 588; Mature: 587

Protein sequence:

>588_residues
MSKRTTYCGLVTEAFLGQEITLKGWVNNRRDLGGLIFVDLRDREGIVQVVFNPAFSEEALKIAETVRSEYVVEVQGTVTK
RDPETVNPKIKTGQVEVQVTNIKVINKSETPPFSINEENVNVDENIRLKYRYLDLRRQELAQTFKMRHQITRSIRQYLDD
EGFFDIETPVLTKSTPEGARDYLVPSRVHDGEFYALPQSPQLFKQLLMISGFDKYYQIVKCFRDEDLRADRQPEFTQVDI
EMSFVDQEDVMQMGEEMLKKVVKEVKGVEINGAFPRMTYKEAMRRYGSDKPDTRFEMELIDVSQLGRDMDFKVFKDTVEN
DGEIKAIVAKGAAEQYTRKDMDALTEFVNIYGAKGLAWVKVVEDGLTGPIGRFFETENVETLLTLTGAEAGDLVMFVADK
PNVVAQSLGALRVKLAKELGLIDETKLNFLWVTDWPLLEYDEDAKRYVAAHHPFTSPKEADIAKLGTAPEEAEANAYDIV
LNGYELGGGSIRIHDGELQEKMFEVLGFTKEQAQEQFGFLLDAFKYGAPPHGGIALGLDRLVMLLTNRTNLRDTIAFPKT
ASATCLLTNAPGEVSDKQLEELSLRIRH

Sequences:

>Translated_588_residues
MSKRTTYCGLVTEAFLGQEITLKGWVNNRRDLGGLIFVDLRDREGIVQVVFNPAFSEEALKIAETVRSEYVVEVQGTVTK
RDPETVNPKIKTGQVEVQVTNIKVINKSETPPFSINEENVNVDENIRLKYRYLDLRRQELAQTFKMRHQITRSIRQYLDD
EGFFDIETPVLTKSTPEGARDYLVPSRVHDGEFYALPQSPQLFKQLLMISGFDKYYQIVKCFRDEDLRADRQPEFTQVDI
EMSFVDQEDVMQMGEEMLKKVVKEVKGVEINGAFPRMTYKEAMRRYGSDKPDTRFEMELIDVSQLGRDMDFKVFKDTVEN
DGEIKAIVAKGAAEQYTRKDMDALTEFVNIYGAKGLAWVKVVEDGLTGPIGRFFETENVETLLTLTGAEAGDLVMFVADK
PNVVAQSLGALRVKLAKELGLIDETKLNFLWVTDWPLLEYDEDAKRYVAAHHPFTSPKEADIAKLGTAPEEAEANAYDIV
LNGYELGGGSIRIHDGELQEKMFEVLGFTKEQAQEQFGFLLDAFKYGAPPHGGIALGLDRLVMLLTNRTNLRDTIAFPKT
ASATCLLTNAPGEVSDKQLEELSLRIRH
>Mature_587_residues
SKRTTYCGLVTEAFLGQEITLKGWVNNRRDLGGLIFVDLRDREGIVQVVFNPAFSEEALKIAETVRSEYVVEVQGTVTKR
DPETVNPKIKTGQVEVQVTNIKVINKSETPPFSINEENVNVDENIRLKYRYLDLRRQELAQTFKMRHQITRSIRQYLDDE
GFFDIETPVLTKSTPEGARDYLVPSRVHDGEFYALPQSPQLFKQLLMISGFDKYYQIVKCFRDEDLRADRQPEFTQVDIE
MSFVDQEDVMQMGEEMLKKVVKEVKGVEINGAFPRMTYKEAMRRYGSDKPDTRFEMELIDVSQLGRDMDFKVFKDTVEND
GEIKAIVAKGAAEQYTRKDMDALTEFVNIYGAKGLAWVKVVEDGLTGPIGRFFETENVETLLTLTGAEAGDLVMFVADKP
NVVAQSLGALRVKLAKELGLIDETKLNFLWVTDWPLLEYDEDAKRYVAAHHPFTSPKEADIAKLGTAPEEAEANAYDIVL
NGYELGGGSIRIHDGELQEKMFEVLGFTKEQAQEQFGFLLDAFKYGAPPHGGIALGLDRLVMLLTNRTNLRDTIAFPKTA
SATCLLTNAPGEVSDKQLEELSLRIRH

Specific function: Unknown

COG id: COG0173

COG function: function code J; Aspartyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI40789249, Length=594, Percent_Identity=41.7508417508418, Blast_Score=438, Evalue=1e-123,
Organism=Homo sapiens, GI194272210, Length=261, Percent_Identity=30.6513409961686, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI5031815, Length=261, Percent_Identity=30.6513409961686, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI45439306, Length=289, Percent_Identity=28.719723183391, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI226491502, Length=255, Percent_Identity=27.843137254902, Blast_Score=89, Evalue=1e-17,
Organism=Escherichia coli, GI1788173, Length=589, Percent_Identity=54.3293718166384, Blast_Score=656, Evalue=0.0,
Organism=Escherichia coli, GI1789256, Length=302, Percent_Identity=26.158940397351, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1790571, Length=302, Percent_Identity=26.158940397351, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1787161, Length=278, Percent_Identity=26.2589928057554, Blast_Score=75, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI32566633, Length=601, Percent_Identity=35.2745424292845, Blast_Score=337, Evalue=1e-92,
Organism=Caenorhabditis elegans, GI71994340, Length=272, Percent_Identity=24.6323529411765, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17535925, Length=272, Percent_Identity=24.6323529411765, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17535927, Length=272, Percent_Identity=24.6323529411765, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17551876, Length=270, Percent_Identity=28.1481481481481, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71984122, Length=303, Percent_Identity=26.0726072607261, Blast_Score=71, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6325153, Length=631, Percent_Identity=34.0729001584786, Blast_Score=301, Evalue=2e-82,
Organism=Saccharomyces cerevisiae, GI6321807, Length=287, Percent_Identity=27.5261324041812, Blast_Score=85, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6323011, Length=264, Percent_Identity=29.1666666666667, Blast_Score=85, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6320242, Length=209, Percent_Identity=29.6650717703349, Blast_Score=82, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6324256, Length=127, Percent_Identity=29.1338582677165, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24584738, Length=602, Percent_Identity=37.2093023255814, Blast_Score=356, Evalue=2e-98,
Organism=Drosophila melanogaster, GI17136276, Length=244, Percent_Identity=28.6885245901639, Blast_Score=99, Evalue=7e-21,
Organism=Drosophila melanogaster, GI24640849, Length=260, Percent_Identity=27.6923076923077, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24640851, Length=260, Percent_Identity=27.6923076923077, Blast_Score=90, Evalue=4e-18,

Paralogues:

None

Copy number: 1320 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYD_STAA1 (A7X344)

Other databases:

- EMBL:   AP009324
- RefSeq:   YP_001442207.1
- ProteinModelPortal:   A7X344
- SMR:   A7X344
- STRING:   A7X344
- EnsemblBacteria:   EBSTAT00000003158
- GeneID:   5559608
- GenomeReviews:   AP009324_GR
- KEGG:   saw:SAHV_1617
- eggNOG:   COG0173
- GeneTree:   EBGT00050000023877
- HOGENOM:   HBG396032
- OMA:   AFPKTQQ
- ProtClustDB:   PRK00476
- BioCyc:   SAUR418127:SAHV_1617-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00044_B
- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR020564
- InterPro:   IPR004524
- InterPro:   IPR018153
- InterPro:   IPR002312
- InterPro:   IPR004115
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365
- Gene3D:   G3DSA:3.30.1360.30
- Gene3D:   G3DSA:2.40.50.140
- PANTHER:   PTHR22594
- PANTHER:   PTHR22594:SF5
- PRINTS:   PR01042
- TIGRFAMs:   TIGR00459

Pfam domain/function: PF02938 GAD; PF00152 tRNA-synt_2; PF01336 tRNA_anti; SSF50249 Nucleic_acid_OB

EC number: =6.1.1.12

Molecular weight: Translated: 66600; Mature: 66468

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKRTTYCGLVTEAFLGQEITLKGWVNNRRDLGGLIFVDLRDREGIVQVVFNPAFSEEAL
CCCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCCEEEEEECCCCCEEEEEECCCCCHHHH
KIAETVRSEYVVEVQGTVTKRDPETVNPKIKTGQVEVQVTNIKVINKSETPPFSINEENV
HHHHHHHHCEEEEEECEEECCCCCCCCCCEECCEEEEEEEEEEEEECCCCCCCCCCCCCC
NVDENIRLKYRYLDLRRQELAQTFKMRHQITRSIRQYLDDEGFFDIETPVLTKSTPEGAR
CCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCEEECCCCCCCH
DYLVPSRVHDGEFYALPQSPQLFKQLLMISGFDKYYQIVKCFRDEDLRADRQPEFTQVDI
HCCCCCEECCCEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEE
EMSFVDQEDVMQMGEEMLKKVVKEVKGVEINGAFPRMTYKEAMRRYGSDKPDTRFEMELI
EEEECCHHHHHHHHHHHHHHHHHHHCCEEECCCCCCHHHHHHHHHHCCCCCCCEEEEEEE
DVSQLGRDMDFKVFKDTVENDGEIKAIVAKGAAEQYTRKDMDALTEFVNIYGAKGLAWVK
EHHHCCCCCCHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCEEEEE
VVEDGLTGPIGRFFETENVETLLTLTGAEAGDLVMFVADKPNVVAQSLGALRVKLAKELG
EECCCCCCCHHHHCCCCCCEEEEEEECCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCC
LIDETKLNFLWVTDWPLLEYDEDAKRYVAAHHPFTSPKEADIAKLGTAPEEAEANAYDIV
CCCCCCCCEEEEECCCCCCCCCHHHHHEEECCCCCCCCCCCHHHCCCCCCCCCCCEEEEE
LNGYELGGGSIRIHDGELQEKMFEVLGFTKEQAQEQFGFLLDAFKYGAPPHGGIALGLDR
EEEEEECCCEEEEECCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
LVMLLTNRTNLRDTIAFPKTASATCLLTNAPGEVSDKQLEELSLRIRH
HHHHHHCCCCCCHHCCCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCC
>Mature Secondary Structure 
SKRTTYCGLVTEAFLGQEITLKGWVNNRRDLGGLIFVDLRDREGIVQVVFNPAFSEEAL
CCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCCEEEEEECCCCCEEEEEECCCCCHHHH
KIAETVRSEYVVEVQGTVTKRDPETVNPKIKTGQVEVQVTNIKVINKSETPPFSINEENV
HHHHHHHHCEEEEEECEEECCCCCCCCCCEECCEEEEEEEEEEEEECCCCCCCCCCCCCC
NVDENIRLKYRYLDLRRQELAQTFKMRHQITRSIRQYLDDEGFFDIETPVLTKSTPEGAR
CCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCEEECCCCCCCH
DYLVPSRVHDGEFYALPQSPQLFKQLLMISGFDKYYQIVKCFRDEDLRADRQPEFTQVDI
HCCCCCEECCCEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEE
EMSFVDQEDVMQMGEEMLKKVVKEVKGVEINGAFPRMTYKEAMRRYGSDKPDTRFEMELI
EEEECCHHHHHHHHHHHHHHHHHHHCCEEECCCCCCHHHHHHHHHHCCCCCCCEEEEEEE
DVSQLGRDMDFKVFKDTVENDGEIKAIVAKGAAEQYTRKDMDALTEFVNIYGAKGLAWVK
EHHHCCCCCCHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCEEEEE
VVEDGLTGPIGRFFETENVETLLTLTGAEAGDLVMFVADKPNVVAQSLGALRVKLAKELG
EECCCCCCCHHHHCCCCCCEEEEEEECCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCC
LIDETKLNFLWVTDWPLLEYDEDAKRYVAAHHPFTSPKEADIAKLGTAPEEAEANAYDIV
CCCCCCCCEEEEECCCCCCCCCHHHHHEEECCCCCCCCCCCHHHCCCCCCCCCCCEEEEE
LNGYELGGGSIRIHDGELQEKMFEVLGFTKEQAQEQFGFLLDAFKYGAPPHGGIALGLDR
EEEEEECCCEEEEECCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
LVMLLTNRTNLRDTIAFPKTASATCLLTNAPGEVSDKQLEELSLRIRH
HHHHHHCCCCCCHHCCCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA