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The map label for this gene is cymR [H]

Identifier: 57650508

GI number: 57650508

Start: 1710092

End: 1710514

Strand: Reverse

Name: cymR [H]

Synonym: SACOL1681

Alternate gene names: 57650508

Gene position: 1710514-1710092 (Counterclockwise)

Preceding gene: 57650510

Following gene: 57650507

Centisome position: 60.88

GC content: 34.75

Gene sequence:

>423_bases
ATGAAAATTTCTACTAAAGGGAGATATGGACTTACATTGATGATTTCTCTTGCTAAAAAAGAGGGGCAAGGATGTATATC
ATTAAAGTCAATTGCTGAAGAAAATAATTTGAGTGATTTATATTTAGAACAGCTTGTAGGTCCTTTAAGAAATGCGGGGT
TAATTCGAAGTGTACGCGGTGCTAAAGGTGGATACCAATTAAGAGTGCCAGCGGAAGAAATCTCAGCAGGGGATATTATA
AGACTGTTAGAAGGTCCAATTACATTTGTTGAAAGTATTGAATCAGAACCACCTGCGCAAAAACAACTATGGATTCGCAT
GAGAGATGCAGTGAGAGATGTTTTAGATAATACAACATTGAAATATTTAGCGGAATATGTAGATACAAGTGAAGATTTAG
ACGGATACATGTTTTATATTTAA

Upstream 100 bases:

>100_bases
ATGGTTCTGTACTCACATTTGTCACACCTTTCTTATACTATCTTAACTCAAAAAATGCTAAAATGGGAATATCAATATTC
GAATTAAGTGAGGTTATACA

Downstream 100 bases:

>100_bases
TCGTATAAATACTATACTATAACATAAAAACTTCATATTATAATGTTTAGCGAACCTCCTTAGTGGTATATAAATATATA
CATCCAAGGAGGTTTCACTA

Product: Rrf2 family protein

Products: NA

Alternate protein names: Cysteine metabolism repressor [H]

Number of amino acids: Translated: 140; Mature: 140

Protein sequence:

>140_residues
MKISTKGRYGLTLMISLAKKEGQGCISLKSIAEENNLSDLYLEQLVGPLRNAGLIRSVRGAKGGYQLRVPAEEISAGDII
RLLEGPITFVESIESEPPAQKQLWIRMRDAVRDVLDNTTLKYLAEYVDTSEDLDGYMFYI

Sequences:

>Translated_140_residues
MKISTKGRYGLTLMISLAKKEGQGCISLKSIAEENNLSDLYLEQLVGPLRNAGLIRSVRGAKGGYQLRVPAEEISAGDII
RLLEGPITFVESIESEPPAQKQLWIRMRDAVRDVLDNTTLKYLAEYVDTSEDLDGYMFYI
>Mature_140_residues
MKISTKGRYGLTLMISLAKKEGQGCISLKSIAEENNLSDLYLEQLVGPLRNAGLIRSVRGAKGGYQLRVPAEEISAGDII
RLLEGPITFVESIESEPPAQKQLWIRMRDAVRDVLDNTTLKYLAEYVDTSEDLDGYMFYI

Specific function: Master repressor of cysteine metabolism in B.subtilis. Controls the expression of genes involved either in cysteine synthesis from sulfide (cysK), sulfonates (ssu), or methionine (mccAB) or in cystine uptake (tcyP). Activity of CymR is positively regulate

COG id: COG1959

COG function: function code K; Predicted transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH rrf2-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788880, Length=140, Percent_Identity=32.8571428571429, Blast_Score=69, Evalue=1e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000944 [H]

Pfam domain/function: PF02082 Rrf2 [H]

EC number: NA

Molecular weight: Translated: 15643; Mature: 15643

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: PS01332 UPF0074

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKISTKGRYGLTLMISLAKKEGQGCISLKSIAEENNLSDLYLEQLVGPLRNAGLIRSVRG
CCCCCCCCCCEEEEEEEHHHCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHCC
AKGGYQLRVPAEEISAGDIIRLLEGPITFVESIESEPPAQKQLWIRMRDAVRDVLDNTTL
CCCCEEEECCHHHHCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHH
KYLAEYVDTSEDLDGYMFYI
HHHHHHHCCCCCCCCEEEEC
>Mature Secondary Structure
MKISTKGRYGLTLMISLAKKEGQGCISLKSIAEENNLSDLYLEQLVGPLRNAGLIRSVRG
CCCCCCCCCCEEEEEEEHHHCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHCC
AKGGYQLRVPAEEISAGDIIRLLEGPITFVESIESEPPAQKQLWIRMRDAVRDVLDNTTL
CCCCEEEECCHHHHCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHH
KYLAEYVDTSEDLDGYMFYI
HHHHHHHCCCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]