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The map label for this gene is yqkF [H]

Identifier: 57650456

GI number: 57650456

Start: 1579729

End: 1580637

Strand: Direct

Name: yqkF [H]

Synonym: SACOL1543

Alternate gene names: 57650456

Gene position: 1579729-1580637 (Clockwise)

Preceding gene: 57650452

Following gene: 57650459

Centisome position: 56.23

GC content: 31.68

Gene sequence:

>909_bases
ATGCAAAAAAATATATTAAAAAGTGGTATTTCATTATCTGAATTAGGTCTAGGTTGCATGAGTTTAGGTACAGATTTAAA
AAAAGCCGAACAAATTATAGATTGTGCTGTTGAAAATGGTATCACTTATTTTGATACAGCAGATATGTACGATAAAGGTA
TAAATGAATCAGTTGTTGGTAAGGCACTTCTTAAATATCAACAACGCGATGATATTTTTATTGGTACAAAAGTAGGCAAT
CGTTTAACAAAAGATGGCAGTACAACATGGGATCCGAGTAAATCCTATATTAAAGAGGCAGTTAAAGGTTCACTAAAGCG
TTTAGGTATCGATCATATCGATTTATATCAACTTCATGGCGGAACCATTGATGACCCATTAGACGAAACAATAAGCGCAT
TTGATGAATTGAAACAAGAAGGAATTATACGTGCTTACGGTATTTCTTCTATTCGCCCAAATGTAATTGATTATTATTTA
AAACATAGTCAAATCGAAACGATAATGTCTCAATTCAATTTGATTGATAATCGTCCAGAATCATTATTAGATGCAATTCA
CAACAATGATGTTAAAGTATTGGCAAGAGGACCTGTGTCTAAAGGATTATTAACTTCAAACAGTGTTAATGTGCTCGACA
ATAAATTTAAAGATGGTATTTTTGATTATTCTCATGATGAATTGGGTGAAACAATAGCCTCTATTAAAGAAATTGAAAGT
AATTTATCTGCATTGACATTTAGTTATTTAACATCACATGACGTGCTTGGTTCCATCATTGTAGGTGCAAGTAGCGTCGA
CCAATTAAAAGAAAATATTGAAAACTATCATACTAAAGTTAGTTTAGATCAGATTAAAACAGCAAGAGCTCGTGTAAAGG
ATTTGGAATATACCAATCATTTAGTGTAG

Upstream 100 bases:

>100_bases
TTTTTTCATTTAAATCCATTATAATCACGTTCCTTTAAATTCATATTATATATTGATACACTATGCTTGTTAGCTAAAGT
GTATCGAAAGGAGAACAGAC

Downstream 100 bases:

>100_bases
AAGTCATTTTCAGTAATAAAAACAGCAGCATGAGGCGTTTCATTATAAAAATGCCTTACTGCTGTTGTTTATGTACAATT
CGCTATAATTTATGATTATG

Product: aldo/keto reductase family oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>302_residues
MQKNILKSGISLSELGLGCMSLGTDLKKAEQIIDCAVENGITYFDTADMYDKGINESVVGKALLKYQQRDDIFIGTKVGN
RLTKDGSTTWDPSKSYIKEAVKGSLKRLGIDHIDLYQLHGGTIDDPLDETISAFDELKQEGIIRAYGISSIRPNVIDYYL
KHSQIETIMSQFNLIDNRPESLLDAIHNNDVKVLARGPVSKGLLTSNSVNVLDNKFKDGIFDYSHDELGETIASIKEIES
NLSALTFSYLTSHDVLGSIIVGASSVDQLKENIENYHTKVSLDQIKTARARVKDLEYTNHLV

Sequences:

>Translated_302_residues
MQKNILKSGISLSELGLGCMSLGTDLKKAEQIIDCAVENGITYFDTADMYDKGINESVVGKALLKYQQRDDIFIGTKVGN
RLTKDGSTTWDPSKSYIKEAVKGSLKRLGIDHIDLYQLHGGTIDDPLDETISAFDELKQEGIIRAYGISSIRPNVIDYYL
KHSQIETIMSQFNLIDNRPESLLDAIHNNDVKVLARGPVSKGLLTSNSVNVLDNKFKDGIFDYSHDELGETIASIKEIES
NLSALTFSYLTSHDVLGSIIVGASSVDQLKENIENYHTKVSLDQIKTARARVKDLEYTNHLV
>Mature_302_residues
MQKNILKSGISLSELGLGCMSLGTDLKKAEQIIDCAVENGITYFDTADMYDKGINESVVGKALLKYQQRDDIFIGTKVGN
RLTKDGSTTWDPSKSYIKEAVKGSLKRLGIDHIDLYQLHGGTIDDPLDETISAFDELKQEGIIRAYGISSIRPNVIDYYL
KHSQIETIMSQFNLIDNRPESLLDAIHNNDVKVLARGPVSKGLLTSNSVNVLDNKFKDGIFDYSHDELGETIASIKEIES
NLSALTFSYLTSHDVLGSIIVGASSVDQLKENIENYHTKVSLDQIKTARARVKDLEYTNHLV

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI4504825, Length=315, Percent_Identity=26.031746031746, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI27436969, Length=315, Percent_Identity=26.031746031746, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI27436962, Length=308, Percent_Identity=24.025974025974, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI27436964, Length=308, Percent_Identity=24.025974025974, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI27436966, Length=308, Percent_Identity=24.025974025974, Blast_Score=78, Evalue=8e-15,
Organism=Homo sapiens, GI27436971, Length=307, Percent_Identity=23.4527687296417, Blast_Score=75, Evalue=6e-14,
Organism=Escherichia coli, GI87081735, Length=313, Percent_Identity=27.4760383386581, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1788070, Length=302, Percent_Identity=27.8145695364238, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1789199, Length=329, Percent_Identity=28.2674772036474, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1789375, Length=297, Percent_Identity=27.9461279461279, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1787674, Length=290, Percent_Identity=23.7931034482759, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1788081, Length=155, Percent_Identity=34.8387096774194, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI87082198, Length=237, Percent_Identity=27.0042194092827, Blast_Score=61, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI212645785, Length=295, Percent_Identity=27.4576271186441, Blast_Score=75, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6325169, Length=321, Percent_Identity=23.98753894081, Blast_Score=70, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24646155, Length=216, Percent_Identity=30.5555555555556, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24646159, Length=213, Percent_Identity=29.1079812206573, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24640980, Length=315, Percent_Identity=24.1269841269841, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI45549126, Length=317, Percent_Identity=24.2902208201893, Blast_Score=71, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 33506; Mature: 33506

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKNILKSGISLSELGLGCMSLGTDLKKAEQIIDCAVENGITYFDTADMYDKGINESVVG
CCCCHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEECHHHHHCCCCHHHHH
KALLKYQQRDDIFIGTKVGNRLTKDGSTTWDPSKSYIKEAVKGSLKRLGIDHIDLYQLHG
HHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECC
GTIDDPLDETISAFDELKQEGIIRAYGISSIRPNVIDYYLKHSQIETIMSQFNLIDNRPE
CCCCCHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHH
SLLDAIHNNDVKVLARGPVSKGLLTSNSVNVLDNKFKDGIFDYSHDELGETIASIKEIES
HHHHHHCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
NLSALTFSYLTSHDVLGSIIVGASSVDQLKENIENYHTKVSLDQIKTARARVKDLEYTNH
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
LV
CC
>Mature Secondary Structure
MQKNILKSGISLSELGLGCMSLGTDLKKAEQIIDCAVENGITYFDTADMYDKGINESVVG
CCCCHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEECHHHHHCCCCHHHHH
KALLKYQQRDDIFIGTKVGNRLTKDGSTTWDPSKSYIKEAVKGSLKRLGIDHIDLYQLHG
HHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECC
GTIDDPLDETISAFDELKQEGIIRAYGISSIRPNVIDYYLKHSQIETIMSQFNLIDNRPE
CCCCCHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHH
SLLDAIHNNDVKVLARGPVSKGLLTSNSVNVLDNKFKDGIFDYSHDELGETIASIKEIES
HHHHHHCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
NLSALTFSYLTSHDVLGSIIVGASSVDQLKENIENYHTKVSLDQIKTARARVKDLEYTNH
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
LV
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]