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The map label for this gene is xerD

Identifier: 57650453

GI number: 57650453

Start: 1577615

End: 1578502

Strand: Reverse

Name: xerD

Synonym: SACOL1540

Alternate gene names: 57650453

Gene position: 1578502-1577615 (Counterclockwise)

Preceding gene: 57650454

Following gene: 57650451

Centisome position: 56.19

GC content: 33.33

Gene sequence:

>888_bases
ATGGAAACAATTATTGAAGAATATTTGCGTTTTATACAAATTGAAAAAGGACTAAGTTCTAACACAATTGGTGCTTATAG
ACGTGATTTGAAAAAGTATCAAGATTATATGACTGAACATCATATCTCGCATATTGATTTTATAGATCGACAATTAATTC
AAGAGTGTTTGGGGCATTTAATAGACCAAGGGCAATCTGCTAAATCTATTGCGCGATTTATTTCAACAATCCGTAGTTTT
CATCAATTTGCTATAAGAGAAAAATATGCGGCGAAAGATCCAACGGTATTATTAGATTCACCAAAATATGACAAAAAATT
GCCTGACGTTTTAAATGTTGACGAAGTGTTGGCTTTATTAGAAACGCCAGATTTAAATAAAATTAATGGATATCGTGATC
GTACGATGTTAGAACTTCTGTACGCAACGGGAATGCGTGTATCTGAATTGATACATTTAGAGTTAGAAAACGTGAACTTA
ATAATGGGATTTGTACGCGTATTTGGTAAAGGCGATAAAGAAAGAATTGTACCATTAGGCGACGCAGTCATTGAGTACTT
AACTACTTATATTGAAACGATTAGACCGCAACTTTTAAAAAAGACTGTTACTGAAGTCTTATTTTTAAATATGCATGGTA
AACCTTTATCACGACAAGCAATATGGAAAATGATTAAACAAAATGGTGTAAAGGCAAACATTAAAAAGACGTTAACGCCA
CATACGTTACGCCACTCTTTTGCGACACATTTATTGGAAAATGGCGCAGATTTAAGAGCAGTGCAAGAGATGTTAGGTCA
CTCTGACATATCTACTACCCAACTCTATACACATGTTTCGAAATCTCAAATTAGAAAAATGTATAACCAATTTCATCCTA
GAGCATAA

Upstream 100 bases:

>100_bases
TTTAACTTTCCATGGTGTGTGTGAAACGTGCCAAGCTAAAGGTAAAGGATAGTAAATTGCGTAGGTTAAATTAACCTTCG
CTTTTTTTAGAGGTGTGGTT

Downstream 100 bases:

>100_bases
AGTGAACAATAACTCAAAAGTCACAATACACATGACTAAAAATGTCTGTGCTATTGTGGCTTTTTTAAATTGGTTGATTA
ATTACGTCTATGTTTTCTTA

Product: tyrosine recombinase XerD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
METIIEEYLRFIQIEKGLSSNTIGAYRRDLKKYQDYMTEHHISHIDFIDRQLIQECLGHLIDQGQSAKSIARFISTIRSF
HQFAIREKYAAKDPTVLLDSPKYDKKLPDVLNVDEVLALLETPDLNKINGYRDRTMLELLYATGMRVSELIHLELENVNL
IMGFVRVFGKGDKERIVPLGDAVIEYLTTYIETIRPQLLKKTVTEVLFLNMHGKPLSRQAIWKMIKQNGVKANIKKTLTP
HTLRHSFATHLLENGADLRAVQEMLGHSDISTTQLYTHVSKSQIRKMYNQFHPRA

Sequences:

>Translated_295_residues
METIIEEYLRFIQIEKGLSSNTIGAYRRDLKKYQDYMTEHHISHIDFIDRQLIQECLGHLIDQGQSAKSIARFISTIRSF
HQFAIREKYAAKDPTVLLDSPKYDKKLPDVLNVDEVLALLETPDLNKINGYRDRTMLELLYATGMRVSELIHLELENVNL
IMGFVRVFGKGDKERIVPLGDAVIEYLTTYIETIRPQLLKKTVTEVLFLNMHGKPLSRQAIWKMIKQNGVKANIKKTLTP
HTLRHSFATHLLENGADLRAVQEMLGHSDISTTQLYTHVSKSQIRKMYNQFHPRA
>Mature_295_residues
METIIEEYLRFIQIEKGLSSNTIGAYRRDLKKYQDYMTEHHISHIDFIDRQLIQECLGHLIDQGQSAKSIARFISTIRSF
HQFAIREKYAAKDPTVLLDSPKYDKKLPDVLNVDEVLALLETPDLNKINGYRDRTMLELLYATGMRVSELIHLELENVNL
IMGFVRVFGKGDKERIVPLGDAVIEYLTTYIETIRPQLLKKTVTEVLFLNMHGKPLSRQAIWKMIKQNGVKANIKKTLTP
HTLRHSFATHLLENGADLRAVQEMLGHSDISTTQLYTHVSKSQIRKMYNQFHPRA

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily

Homologues:

Organism=Escherichia coli, GI1789261, Length=292, Percent_Identity=43.8356164383562, Blast_Score=251, Evalue=3e-68,
Organism=Escherichia coli, GI1790244, Length=295, Percent_Identity=34.2372881355932, Blast_Score=191, Evalue=6e-50,
Organism=Escherichia coli, GI1790768, Length=181, Percent_Identity=28.7292817679558, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1790767, Length=196, Percent_Identity=27.0408163265306, Blast_Score=72, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): XERD_STAAC (Q5HFS5)

Other databases:

- EMBL:   CP000046
- RefSeq:   YP_186382.1
- ProteinModelPortal:   Q5HFS5
- SMR:   Q5HFS5
- STRING:   Q5HFS5
- EnsemblBacteria:   EBSTAT00000009215
- GeneID:   3237654
- GenomeReviews:   CP000046_GR
- KEGG:   sac:SACOL1540
- TIGR:   SACOL1540
- eggNOG:   COG4974
- GeneTree:   EBGT00050000024184
- HOGENOM:   HBG727654
- OMA:   AINIKMG
- ProtClustDB:   CLSK885391
- BioCyc:   SAUR93062:SACOL1540-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01807
- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932
- Gene3D:   G3DSA:1.10.150.130
- Gene3D:   G3DSA:1.10.443.10
- TIGRFAMs:   TIGR02225

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase; SSF56349 DNA_brk_join_enz; SSF47823 L_intgrse_like_N

EC number: NA

Molecular weight: Translated: 34133; Mature: 34133

Theoretical pI: Translated: 9.46; Mature: 9.46

Prosite motif: NA

Important sites: ACT_SITE 146-146 ACT_SITE 170-170 ACT_SITE 241-241 ACT_SITE 244-244 ACT_SITE 267-267 ACT_SITE 276-276

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METIIEEYLRFIQIEKGLSSNTIGAYRRDLKKYQDYMTEHHISHIDFIDRQLIQECLGHL
CHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IDQGQSAKSIARFISTIRSFHQFAIREKYAAKDPTVLLDSPKYDKKLPDVLNVDEVLALL
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCHHHHHHHH
ETPDLNKINGYRDRTMLELLYATGMRVSELIHLELENVNLIMGFVRVFGKGDKERIVPLG
CCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHH
DAVIEYLTTYIETIRPQLLKKTVTEVLFLNMHGKPLSRQAIWKMIKQNGVKANIKKTLTP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCHHHHCCH
HTLRHSFATHLLENGADLRAVQEMLGHSDISTTQLYTHVSKSQIRKMYNQFHPRA
HHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
METIIEEYLRFIQIEKGLSSNTIGAYRRDLKKYQDYMTEHHISHIDFIDRQLIQECLGHL
CHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IDQGQSAKSIARFISTIRSFHQFAIREKYAAKDPTVLLDSPKYDKKLPDVLNVDEVLALL
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCHHHHHHHH
ETPDLNKINGYRDRTMLELLYATGMRVSELIHLELENVNLIMGFVRVFGKGDKERIVPLG
CCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHH
DAVIEYLTTYIETIRPQLLKKTVTEVLFLNMHGKPLSRQAIWKMIKQNGVKANIKKTLTP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCHHHHCCH
HTLRHSFATHLLENGADLRAVQEMLGHSDISTTQLYTHVSKSQIRKMYNQFHPRA
HHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA