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The map label for this gene is asnC [H]

Identifier: 57650409

GI number: 57650409

Start: 1532975

End: 1534267

Strand: Reverse

Name: asnC [H]

Synonym: SACOL1494

Alternate gene names: 57650409

Gene position: 1534267-1532975 (Counterclockwise)

Preceding gene: 57650410

Following gene: 57650408

Centisome position: 54.61

GC content: 35.27

Gene sequence:

>1293_bases
ATGAAAACAACGATTAAACAAGCGAAAGATCATTTAAACCAAGACGTTACAATTGGTGCTTGGTTAACAAATAAACGTTC
AAGTGGTAAAATCGCCTTTTTACAATTACGTGATGGAACAGGCTTTATGCAAGGCGTAGTAGTTAAATCAGAAGTTGATG
AAGAGGTATTCAAACTTGCGAAAGAAATTACTCAAGAATCATCTCTATACGTTACAGGCACAATTACAGAAGATAATCGT
TCTGACTTAGGATACGAAATGCAAGTGAAATCAATTGAAGTTATTTCAGAAGCGCATGACTATCCGATTACACCTAAAAA
TCATGGTACAGAATTCTTAATGGATCACCGTCATTTATGGTTACGTTCTAAAAAACAACATGCTGTAATGAAAATTAGAA
ATGAAGTTATTCGTGCAACGTATGAATTTTTCAACAAAGATGGATTTACAAAGGTTGATCCACCAATTTTGACAGCAAGT
GCGCCAGAAGGTACAAGTGAATTATTCCATACTAAATACTTTGATCAAGATGCGTTTTTATCTCAAAGTGGTCAGTTATA
CTTAGAAGCTGCAGCAATGGCACACGGAAAAGTATTTTCATTTGGTCCAACTTTCAGAGCTGAAAAATCAAAAACACGTA
GACACTTGATCGAGTTCTGGATGATTGAAGGAGAAATGGCTTTCACAAATCATGCTGAAAGTTTAGAAATTCAAGAACAA
TATGTAACACATGTTGTAAAATCAGTTTTAGAAAATTGTAAACTAGAGTTGAAAATTTTAGAGCGTGATACATCAAAACT
TGAAAAAGTTGCGACACCATTCCCTAGAATTTCATATGATGATGCAATTGAATTCTTAAAAGCAGAAGGCTTTGATGATA
TTGAATGGGGCGAAGATTTTGGTGCGCCACATGAAACAGCCATTGCTAATCATTATGATTTACCGGTGTTTATTACTAAT
TATCCAACTAAAATTAAGCCTTTCTATATGCAACCAAATCCTGAAAATGAAGAAACTGTATTATGTGCAGACTTAATTGC
ACCTGAAGGATACGGTGAAATTATTGGTGGATCTGAACGTGTGGATGACTTAGAATTGTTAGAACAACGCGTTAAAGAAC
ATGGATTAGACGAAGAAGCATATAGTTACTACTTAGACTTACGTCGTTATGGTAGTGTGCCACACTGTGGATTTGGTTTA
GGTTTAGAGCGTACAGTAGCATGGATTTCTGGTGTTGAACACGTTCGTGAAACAGCGCCATTCCCAAGATTATTAAACCG
TTTATATCCATAA

Upstream 100 bases:

>100_bases
CATTTACACGTTATCTTTTAGTCTAGTTCTAGAACTTGAAAGCGGATTTTGTTAAAATGAATGAGTATTGTATAACGAAA
AAATAAATAGGAGAATGGTT

Downstream 100 bases:

>100_bases
GTTTTAGGGTCGTTACTTAAAATATATATTATGATAATAAAAAGAATCGTCCAGCCTATATTAATAGCTGGGCGATTTAT
TCTTGGAAAATGAAGATTGA

Product: asparaginyl-tRNA synthetase

Products: NA

Alternate protein names: Asparagine--tRNA ligase; AsnRS [H]

Number of amino acids: Translated: 430; Mature: 430

Protein sequence:

>430_residues
MKTTIKQAKDHLNQDVTIGAWLTNKRSSGKIAFLQLRDGTGFMQGVVVKSEVDEEVFKLAKEITQESSLYVTGTITEDNR
SDLGYEMQVKSIEVISEAHDYPITPKNHGTEFLMDHRHLWLRSKKQHAVMKIRNEVIRATYEFFNKDGFTKVDPPILTAS
APEGTSELFHTKYFDQDAFLSQSGQLYLEAAAMAHGKVFSFGPTFRAEKSKTRRHLIEFWMIEGEMAFTNHAESLEIQEQ
YVTHVVKSVLENCKLELKILERDTSKLEKVATPFPRISYDDAIEFLKAEGFDDIEWGEDFGAPHETAIANHYDLPVFITN
YPTKIKPFYMQPNPENEETVLCADLIAPEGYGEIIGGSERVDDLELLEQRVKEHGLDEEAYSYYLDLRRYGSVPHCGFGL
GLERTVAWISGVEHVRETAPFPRLLNRLYP

Sequences:

>Translated_430_residues
MKTTIKQAKDHLNQDVTIGAWLTNKRSSGKIAFLQLRDGTGFMQGVVVKSEVDEEVFKLAKEITQESSLYVTGTITEDNR
SDLGYEMQVKSIEVISEAHDYPITPKNHGTEFLMDHRHLWLRSKKQHAVMKIRNEVIRATYEFFNKDGFTKVDPPILTAS
APEGTSELFHTKYFDQDAFLSQSGQLYLEAAAMAHGKVFSFGPTFRAEKSKTRRHLIEFWMIEGEMAFTNHAESLEIQEQ
YVTHVVKSVLENCKLELKILERDTSKLEKVATPFPRISYDDAIEFLKAEGFDDIEWGEDFGAPHETAIANHYDLPVFITN
YPTKIKPFYMQPNPENEETVLCADLIAPEGYGEIIGGSERVDDLELLEQRVKEHGLDEEAYSYYLDLRRYGSVPHCGFGL
GLERTVAWISGVEHVRETAPFPRLLNRLYP
>Mature_430_residues
MKTTIKQAKDHLNQDVTIGAWLTNKRSSGKIAFLQLRDGTGFMQGVVVKSEVDEEVFKLAKEITQESSLYVTGTITEDNR
SDLGYEMQVKSIEVISEAHDYPITPKNHGTEFLMDHRHLWLRSKKQHAVMKIRNEVIRATYEFFNKDGFTKVDPPILTAS
APEGTSELFHTKYFDQDAFLSQSGQLYLEAAAMAHGKVFSFGPTFRAEKSKTRRHLIEFWMIEGEMAFTNHAESLEIQEQ
YVTHVVKSVLENCKLELKILERDTSKLEKVATPFPRISYDDAIEFLKAEGFDDIEWGEDFGAPHETAIANHYDLPVFITN
YPTKIKPFYMQPNPENEETVLCADLIAPEGYGEIIGGSERVDDLELLEQRVKEHGLDEEAYSYYLDLRRYGSVPHCGFGL
GLERTVAWISGVEHVRETAPFPRLLNRLYP

Specific function: Unknown

COG id: COG0017

COG function: function code J; Aspartyl/asparaginyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI226491502, Length=444, Percent_Identity=35.3603603603604, Blast_Score=263, Evalue=3e-70,
Organism=Homo sapiens, GI4758762, Length=432, Percent_Identity=33.3333333333333, Blast_Score=230, Evalue=2e-60,
Organism=Homo sapiens, GI45439306, Length=451, Percent_Identity=31.2638580931264, Blast_Score=191, Evalue=1e-48,
Organism=Homo sapiens, GI40789249, Length=236, Percent_Identity=28.8135593220339, Blast_Score=76, Evalue=8e-14,
Organism=Escherichia coli, GI1787161, Length=457, Percent_Identity=37.855579868709, Blast_Score=292, Evalue=2e-80,
Organism=Escherichia coli, GI1788173, Length=246, Percent_Identity=26.8292682926829, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1790571, Length=458, Percent_Identity=23.7991266375546, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1789256, Length=452, Percent_Identity=23.4513274336283, Blast_Score=89, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI71984122, Length=440, Percent_Identity=34.5454545454545, Blast_Score=251, Evalue=7e-67,
Organism=Caenorhabditis elegans, GI17556372, Length=411, Percent_Identity=30.9002433090024, Blast_Score=167, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI17551876, Length=460, Percent_Identity=28.2608695652174, Blast_Score=165, Evalue=5e-41,
Organism=Caenorhabditis elegans, GI32566633, Length=286, Percent_Identity=26.2237762237762, Blast_Score=79, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6321807, Length=443, Percent_Identity=33.6343115124154, Blast_Score=258, Evalue=1e-69,
Organism=Saccharomyces cerevisiae, GI6319872, Length=469, Percent_Identity=32.6226012793177, Blast_Score=229, Evalue=5e-61,
Organism=Saccharomyces cerevisiae, GI6323011, Length=464, Percent_Identity=28.8793103448276, Blast_Score=163, Evalue=5e-41,
Organism=Saccharomyces cerevisiae, GI6325153, Length=261, Percent_Identity=29.1187739463602, Blast_Score=70, Evalue=5e-13,
Organism=Drosophila melanogaster, GI19921528, Length=442, Percent_Identity=34.841628959276, Blast_Score=238, Evalue=6e-63,
Organism=Drosophila melanogaster, GI19922416, Length=444, Percent_Identity=31.981981981982, Blast_Score=213, Evalue=2e-55,
Organism=Drosophila melanogaster, GI17136276, Length=438, Percent_Identity=29.9086757990868, Blast_Score=174, Evalue=8e-44,

Paralogues:

None

Copy number: 80 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR004522
- InterPro:   IPR002312
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00152 tRNA-synt_2; PF01336 tRNA_anti [H]

EC number: =6.1.1.22 [H]

Molecular weight: Translated: 49158; Mature: 49158

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTTIKQAKDHLNQDVTIGAWLTNKRSSGKIAFLQLRDGTGFMQGVVVKSEVDEEVFKLA
CCCHHHHHHHHCCCCEEEEEEEECCCCCCCEEEEEEECCCCCHHHEEEHHHHHHHHHHHH
KEITQESSLYVTGTITEDNRSDLGYEMQVKSIEVISEAHDYPITPKNHGTEFLMDHRHLW
HHHHCCCCEEEEEEEECCCCCCCCEEEEHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
LRSKKQHAVMKIRNEVIRATYEFFNKDGFTKVDPPILTASAPEGTSELFHTKYFDQDAFL
HHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCHHHHHHHHHCCCHHHH
SQSGQLYLEAAAMAHGKVFSFGPTFRAEKSKTRRHLIEFWMIEGEMAFTNHAESLEIQEQ
CCCCCEEEEEEHHHCCCEEECCCCCCCHHHHHHHHHHHHHEECCCEEECCCCCHHHHHHH
YVTHVVKSVLENCKLELKILERDTSKLEKVATPFPRISYDDAIEFLKAEGFDDIEWGEDF
HHHHHHHHHHHCCCEEEEEEHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCHHC
GAPHETAIANHYDLPVFITNYPTKIKPFYMQPNPENEETVLCADLIAPEGYGEIIGGSER
CCCCHHHHCCCCCCCEEEECCCCCCEEEEECCCCCCCCEEEEEHHHCCCCCCCCCCCCCC
VDDLELLEQRVKEHGLDEEAYSYYLDLRRYGSVPHCGFGLGLERTVAWISGVEHVRETAP
CHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCC
FPRLLNRLYP
HHHHHHHHCC
>Mature Secondary Structure
MKTTIKQAKDHLNQDVTIGAWLTNKRSSGKIAFLQLRDGTGFMQGVVVKSEVDEEVFKLA
CCCHHHHHHHHCCCCEEEEEEEECCCCCCCEEEEEEECCCCCHHHEEEHHHHHHHHHHHH
KEITQESSLYVTGTITEDNRSDLGYEMQVKSIEVISEAHDYPITPKNHGTEFLMDHRHLW
HHHHCCCCEEEEEEEECCCCCCCCEEEEHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
LRSKKQHAVMKIRNEVIRATYEFFNKDGFTKVDPPILTASAPEGTSELFHTKYFDQDAFL
HHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCHHHHHHHHHCCCHHHH
SQSGQLYLEAAAMAHGKVFSFGPTFRAEKSKTRRHLIEFWMIEGEMAFTNHAESLEIQEQ
CCCCCEEEEEEHHHCCCEEECCCCCCCHHHHHHHHHHHHHEECCCEEECCCCCHHHHHHH
YVTHVVKSVLENCKLELKILERDTSKLEKVATPFPRISYDDAIEFLKAEGFDDIEWGEDF
HHHHHHHHHHHCCCEEEEEEHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCHHC
GAPHETAIANHYDLPVFITNYPTKIKPFYMQPNPENEETVLCADLIAPEGYGEIIGGSER
CCCCHHHHCCCCCCCEEEECCCCCCEEEEECCCCCCCCEEEEEHHHCCCCCCCCCCCCCC
VDDLELLEQRVKEHGLDEEAYSYYLDLRRYGSVPHCGFGLGLERTVAWISGVEHVRETAP
CHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCC
FPRLLNRLYP
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA