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The map label for this gene is prc [C]

Identifier: 57650378

GI number: 57650378

Start: 1469477

End: 1470967

Strand: Reverse

Name: prc [C]

Synonym: SACOL1455

Alternate gene names: 57650378

Gene position: 1470967-1469477 (Counterclockwise)

Preceding gene: 57650379

Following gene: 57651918

Centisome position: 52.36

GC content: 30.65

Gene sequence:

>1491_bases
ATGGATGATAAGCAACACACATCTTCATCCGATGATGAACGCGCTGAAATTGCAACAAGCAATCAAGACCAAGAAACTAA
TTCATCGAAACGCGTTCACTTAAAACGTTGGCAATTCATATCAATATTAATTGGTACAATCCTAATAACAGCTGTCATCA
CAGTTGTTGCATATATTTTTATAAATCAAAAAATAAGTGGTTTAAACAAAACTGATCAATCAAACTTAAATAAAATTGAA
AATGTGTATAAAATCTTAAATAGTGATTATTACAAAAAACAGGACTCTGACAAGTTAAGTAAAGCTGCAATTGATGGCAT
GGTCAAAGAATTAAAAGATCCTTATTCTGAATATTTAACAAAAGAACAAACGAAATCCTTTAATGAAGGTGTTTCAGGTG
ATTTTGTAGGTATTGGTGCAGAAATGCAAAAGAAAAATGATCAAATTATGGTTACTAGTCCTATGAAGGGATCTCCAGCA
GAACGTGCTGGCATTCGTCCTAAAGATGTCATTACTAAAGTAAATGGAAAATCAATTAAAGGTAAAGCATTAGATGAAGT
TGTCAAAGATGTTCGTGGTAAAGAAAACACTGAAGTCACTTTAACTGTTCAACGAGGTAGTGAAGAAAAAGACGTTAAGA
TTAAACGTGAAAAAATTCATGTTAAAAGTGTTGAGTATAAGAAAAAAGGTAAAGTTGGAGTTATTACTATTAATAAATTC
CAGAATGATACATCAGGTGAATTGAAAGATGCAGTTCTAAAAGCTCACAAAGATGGTTTGAAAAAGATTGTTTTAGATTT
AAGAAATAATCCAGGTGGACTACTAGATGAAGCTGTTAAAATGGCAAATATTTTTATCGATAAAGGAAAAACTGTTGTTA
AACTAGAAAAAGGTAAAGATACTGAAGCAATTCAAACTTCTAATGATGCGTTAAAAGAAGCGAAAGACATGGATATATCC
ATCTTAGTGAATGAAGGTTCAGCTAGCGCTTCTGAAGTGTTTACTGGTGCGCTAAAAGACTATAATAAAGCTAAAGTTTA
TGGGTCAAAAACATTCGGCAAAGGTGTCGTACAAACTACAAGAGAGTTTAAGGATGGTTCATTGTTAAAATATACTGAAA
TGAAATGGTTAACGCCAGATGGTCATTATATTCACGGTAAAGGCATTAAACCAGACGTTACTATTGACACACCTAAATAT
CAATCTTTAAATGTCATTCCTAATACGAAAACATTTAAAGTTGGAGACGATGATAAAAATATTAAAACTATTAAAATTGG
TTTATCAGCTTTAGGTTATAAAGTTGATAATGAATCAACGCAATTTGATAAAGCTTTAGAAAATCAAGTTAAAGCTTTCC
AACAAGCGAATAAACTTGAGGTAACTGGTGAATTTAATAAAGAAACGAATAATAAATTTACTGAGTTATTAGTTGAAAAA
GCTAATAAACATGATGATGTTCTCGATAAGTTGATTAATATTTTAAAATAA

Upstream 100 bases:

>100_bases
AATCAATTATAGTGAAATATGGTGCGCTATCTTGCATAAATTGATATGATTAACTACACAGAATTTAAAAGTACATAATA
CATAATAAGGAAGTGATACA

Downstream 100 bases:

>100_bases
GCGATACACACTACTAAAATTGTATTATTATTATGTTAATGACACGCCTCCTAAATTTGCAAAGATAGCAATTTAGGAGG
CGTGTTTATTTTTATTGACG

Product: carboxyl-terminal protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 496; Mature: 496

Protein sequence:

>496_residues
MDDKQHTSSSDDERAEIATSNQDQETNSSKRVHLKRWQFISILIGTILITAVITVVAYIFINQKISGLNKTDQSNLNKIE
NVYKILNSDYYKKQDSDKLSKAAIDGMVKELKDPYSEYLTKEQTKSFNEGVSGDFVGIGAEMQKKNDQIMVTSPMKGSPA
ERAGIRPKDVITKVNGKSIKGKALDEVVKDVRGKENTEVTLTVQRGSEEKDVKIKREKIHVKSVEYKKKGKVGVITINKF
QNDTSGELKDAVLKAHKDGLKKIVLDLRNNPGGLLDEAVKMANIFIDKGKTVVKLEKGKDTEAIQTSNDALKEAKDMDIS
ILVNEGSASASEVFTGALKDYNKAKVYGSKTFGKGVVQTTREFKDGSLLKYTEMKWLTPDGHYIHGKGIKPDVTIDTPKY
QSLNVIPNTKTFKVGDDDKNIKTIKIGLSALGYKVDNESTQFDKALENQVKAFQQANKLEVTGEFNKETNNKFTELLVEK
ANKHDDVLDKLINILK

Sequences:

>Translated_496_residues
MDDKQHTSSSDDERAEIATSNQDQETNSSKRVHLKRWQFISILIGTILITAVITVVAYIFINQKISGLNKTDQSNLNKIE
NVYKILNSDYYKKQDSDKLSKAAIDGMVKELKDPYSEYLTKEQTKSFNEGVSGDFVGIGAEMQKKNDQIMVTSPMKGSPA
ERAGIRPKDVITKVNGKSIKGKALDEVVKDVRGKENTEVTLTVQRGSEEKDVKIKREKIHVKSVEYKKKGKVGVITINKF
QNDTSGELKDAVLKAHKDGLKKIVLDLRNNPGGLLDEAVKMANIFIDKGKTVVKLEKGKDTEAIQTSNDALKEAKDMDIS
ILVNEGSASASEVFTGALKDYNKAKVYGSKTFGKGVVQTTREFKDGSLLKYTEMKWLTPDGHYIHGKGIKPDVTIDTPKY
QSLNVIPNTKTFKVGDDDKNIKTIKIGLSALGYKVDNESTQFDKALENQVKAFQQANKLEVTGEFNKETNNKFTELLVEK
ANKHDDVLDKLINILK
>Mature_496_residues
MDDKQHTSSSDDERAEIATSNQDQETNSSKRVHLKRWQFISILIGTILITAVITVVAYIFINQKISGLNKTDQSNLNKIE
NVYKILNSDYYKKQDSDKLSKAAIDGMVKELKDPYSEYLTKEQTKSFNEGVSGDFVGIGAEMQKKNDQIMVTSPMKGSPA
ERAGIRPKDVITKVNGKSIKGKALDEVVKDVRGKENTEVTLTVQRGSEEKDVKIKREKIHVKSVEYKKKGKVGVITINKF
QNDTSGELKDAVLKAHKDGLKKIVLDLRNNPGGLLDEAVKMANIFIDKGKTVVKLEKGKDTEAIQTSNDALKEAKDMDIS
ILVNEGSASASEVFTGALKDYNKAKVYGSKTFGKGVVQTTREFKDGSLLKYTEMKWLTPDGHYIHGKGIKPDVTIDTPKY
QSLNVIPNTKTFKVGDDDKNIKTIKIGLSALGYKVDNESTQFDKALENQVKAFQQANKLEVTGEFNKETNNKFTELLVEK
ANKHDDVLDKLINILK

Specific function: Involved In The Cleavage Of A C-Terminal Peptide Of 11 Residues From The Precursor Form Of Penicillin-Binding Protein 3 (Pbp3). May Be Involved In Protection Of The Bacterium From Thermal And Osmotic Stresses. [C]

COG id: COG0793

COG function: function code M; Periplasmic protease

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1788134, Length=331, Percent_Identity=31.4199395770393, Blast_Score=136, Evalue=4e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR005151
- InterPro:   IPR004447
- InterPro:   IPR002477 [H]

Pfam domain/function: PF00595 PDZ; PF03572 Peptidase_S41; PF01471 PG_binding_1 [H]

EC number: 3.4.21.102 [C]

Molecular weight: Translated: 55278; Mature: 55278

Theoretical pI: Translated: 9.75; Mature: 9.75

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDDKQHTSSSDDERAEIATSNQDQETNSSKRVHLKRWQFISILIGTILITAVITVVAYIF
CCCCCCCCCCCCHHHHHHCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
INQKISGLNKTDQSNLNKIENVYKILNSDYYKKQDSDKLSKAAIDGMVKELKDPYSEYLT
HHHHHCCCCCCCHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KEQTKSFNEGVSGDFVGIGAEMQKKNDQIMVTSPMKGSPAERAGIRPKDVITKVNGKSIK
HHHHHHHHCCCCCCEEEECCHHHCCCCEEEEECCCCCCCHHHCCCCHHHHHEECCCCCCC
GKALDEVVKDVRGKENTEVTLTVQRGSEEKDVKIKREKIHVKSVEYKKKGKVGVITINKF
CHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCEEEHHEEEEEEECHHCCCCEEEEEEECC
QNDTSGELKDAVLKAHKDGLKKIVLDLRNNPGGLLDEAVKMANIFIDKGKTVVKLEKGKD
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHEECCCEEEEEECCCC
TEAIQTSNDALKEAKDMDISILVNEGSASASEVFTGALKDYNKAKVYGSKTFGKGVVQTT
CCHHCCCHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHCCCHHEEECCCCCCCHHHHHH
REFKDGSLLKYTEMKWLTPDGHYIHGKGIKPDVTIDTPKYQSLNVIPNTKTFKVGDDDKN
HHCCCCCEEEEECEEEECCCCCEEECCCCCCCEEECCCCCCEEEECCCCEEEEECCCCCC
IKTIKIGLSALGYKVDNESTQFDKALENQVKAFQQANKLEVTGEFNKETNNKFTELLVEK
EEEEEEEHHHHCEEECCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHH
ANKHDDVLDKLINILK
CCCHHHHHHHHHHHHC
>Mature Secondary Structure
MDDKQHTSSSDDERAEIATSNQDQETNSSKRVHLKRWQFISILIGTILITAVITVVAYIF
CCCCCCCCCCCCHHHHHHCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
INQKISGLNKTDQSNLNKIENVYKILNSDYYKKQDSDKLSKAAIDGMVKELKDPYSEYLT
HHHHHCCCCCCCHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KEQTKSFNEGVSGDFVGIGAEMQKKNDQIMVTSPMKGSPAERAGIRPKDVITKVNGKSIK
HHHHHHHHCCCCCCEEEECCHHHCCCCEEEEECCCCCCCHHHCCCCHHHHHEECCCCCCC
GKALDEVVKDVRGKENTEVTLTVQRGSEEKDVKIKREKIHVKSVEYKKKGKVGVITINKF
CHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCEEEHHEEEEEEECHHCCCCEEEEEEECC
QNDTSGELKDAVLKAHKDGLKKIVLDLRNNPGGLLDEAVKMANIFIDKGKTVVKLEKGKD
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHEECCCEEEEEECCCC
TEAIQTSNDALKEAKDMDISILVNEGSASASEVFTGALKDYNKAKVYGSKTFGKGVVQTT
CCHHCCCHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHCCCHHEEECCCCCCCHHHHHH
REFKDGSLLKYTEMKWLTPDGHYIHGKGIKPDVTIDTPKYQSLNVIPNTKTFKVGDDDKN
HHCCCCCEEEEECEEEECCCCCEEECCCCCCCEEECCCCCCEEEECCCCEEEEECCCCCC
IKTIKIGLSALGYKVDNESTQFDKALENQVKAFQQANKLEVTGEFNKETNNKFTELLVEK
EEEEEEEHHHHCEEECCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHH
ANKHDDVLDKLINILK
CCCHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Cleavage of the C-terminal peptide from the precursor form of penicillin-binding protein 3 [C]

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA