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The map label for this gene is alsT [H]

Identifier: 57650360

GI number: 57650360

Start: 1400622

End: 1402097

Strand: Direct

Name: alsT [H]

Synonym: SACOL1392

Alternate gene names: 57650360

Gene position: 1400622-1402097 (Clockwise)

Preceding gene: 57650359

Following gene: 57650361

Centisome position: 49.85

GC content: 35.37

Gene sequence:

>1476_bases
TTGAAAGATTTCGATAGTTTAATACCTGGATGGTTTAAAGAATTTGTCCATGTTGGTACCGATTTAATATGGTCTCAATA
TTTAATTGGTCTATTATTGACAGCTGGATTCTTCTTTACGATTAGTTCTAAATTCGTTCAATTACGAATGTTACCTGAAA
TGTTTAGAGCTTTAGTAGAACGTCCAGAAACTTTAGAAGATGGTAAGAAGGGTATTTCGCCATTCCAAGCATTTGCGATT
AGTGCTGGTTCGAGAGTTGGTACTGGTAATATTGCTGGTGTTGCGACTGCGATTGTTTTAGGCGGTCCAGGTGCAGTATT
TTGGATGTGGGTTATTGCATTTATAGGTGCAGCGAGTGCATTTATAGAAGCGACTTTGGCTCAGGTTTATAAAGTACATG
ATAAAGATGGTGGATTCCGTGGTGGTCCAGCTTACTATATTACTAAAGGTTTAAATCAAAAATGGCTAGGTATCGTATTT
GCGATTTTAATTACAATTACATTTGCATTTGTATTTAACACAGTGCAATCTAATACAATTGCGGAGTCGTTAAATACGCA
ATATAATATTAGTCCAGTAATCACAGGTATTATTTTAGCAATCGTAACAGCTATTATTATATTTGGTGGTGTACGTAGTA
TTGCTACGTTATCTTCGTTAATTGTACCGATTATGGCTATCATTTACATTGGTATGGTTTTAGTAATATTGCTATTTAAT
TTAGATCAAATTGTTCCTATGATAGGTACGATTATTAAAAGTGCATTTGGTATCGAACAAGTAACTGGTGGCGCTGTAGG
TGCTGCGGTTCTTCAAGGTATCAAACGTGGTTTATTCTCTAACGAAGCTGGTATGGGTTCTGCGCCGAATGCAGCGGCAA
CTGCTGCCGTACCACACCCTGTTAAGCAAGGTTTAATCCAATCATTAGGTGTGTTCTTTGATACAATGTTGGTTTGTACA
GCAACTGCAATCATGATTTTACTATATTCAGGACTGAAATTTGGTGATAACGCACCTCAAGGTGTTGCAGTTACTCAATC
AGCACTTAATGAGCATTTAGGTTCTGCTGGAGGTATTTTCTTAACAATAGCAGTTACACTGTTTGCATTTTCATCTGTTG
TAGGTAATTACTATTACGGTCAATCTAATATTGAATTTTTATCAACAAACCGTGTAATATTATTTATCTTTAGATGTCTT
GTTGTAGTACTTGTCTTTGTCGGTGCAGTTGTAAAAACAGAAACAGTATGGAATACGGCAGACTTATTTATGGGCTTAAT
GGCAATTGTAAACATTATTTCCATTATAGGACTGTCCAATGTAGCTTTTGCATTGATGAAAGATTATCAAAAGCAGAAAA
AAGAAGGCAAGAACCCTGTCTTTAAACCTGAAAACTTAGAAATTAACTTATTTGGAATTAGTGCTTGGGGCGCTAACAAA
TATAAGAACTCTGATAAACAAATATTTTTAATGTAA

Upstream 100 bases:

>100_bases
TATAAGAAATGATGATGTATCTCTATATTTACTGAAGGTTCAATTCGGTCTAATTTTATAGAAGGTACATGATTCATGTA
GAGGATGCGAGGGGTTTATT

Downstream 100 bases:

>100_bases
CGATTCATTATATAAAAATCAAATAAACCCTGAGGTTTTCAAATTAAAGCGAAAATCTCAGGGTTTTAAATTTGTACTCA
ATTATCATCTGTATCATTAC

Product: sodium:alanine symporter family protein

Products: Na (I) [Cytoplasm]; L-alanine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 491; Mature: 491

Protein sequence:

>491_residues
MKDFDSLIPGWFKEFVHVGTDLIWSQYLIGLLLTAGFFFTISSKFVQLRMLPEMFRALVERPETLEDGKKGISPFQAFAI
SAGSRVGTGNIAGVATAIVLGGPGAVFWMWVIAFIGAASAFIEATLAQVYKVHDKDGGFRGGPAYYITKGLNQKWLGIVF
AILITITFAFVFNTVQSNTIAESLNTQYNISPVITGIILAIVTAIIIFGGVRSIATLSSLIVPIMAIIYIGMVLVILLFN
LDQIVPMIGTIIKSAFGIEQVTGGAVGAAVLQGIKRGLFSNEAGMGSAPNAAATAAVPHPVKQGLIQSLGVFFDTMLVCT
ATAIMILLYSGLKFGDNAPQGVAVTQSALNEHLGSAGGIFLTIAVTLFAFSSVVGNYYYGQSNIEFLSTNRVILFIFRCL
VVVLVFVGAVVKTETVWNTADLFMGLMAIVNIISIIGLSNVAFALMKDYQKQKKEGKNPVFKPENLEINLFGISAWGANK
YKNSDKQIFLM

Sequences:

>Translated_491_residues
MKDFDSLIPGWFKEFVHVGTDLIWSQYLIGLLLTAGFFFTISSKFVQLRMLPEMFRALVERPETLEDGKKGISPFQAFAI
SAGSRVGTGNIAGVATAIVLGGPGAVFWMWVIAFIGAASAFIEATLAQVYKVHDKDGGFRGGPAYYITKGLNQKWLGIVF
AILITITFAFVFNTVQSNTIAESLNTQYNISPVITGIILAIVTAIIIFGGVRSIATLSSLIVPIMAIIYIGMVLVILLFN
LDQIVPMIGTIIKSAFGIEQVTGGAVGAAVLQGIKRGLFSNEAGMGSAPNAAATAAVPHPVKQGLIQSLGVFFDTMLVCT
ATAIMILLYSGLKFGDNAPQGVAVTQSALNEHLGSAGGIFLTIAVTLFAFSSVVGNYYYGQSNIEFLSTNRVILFIFRCL
VVVLVFVGAVVKTETVWNTADLFMGLMAIVNIISIIGLSNVAFALMKDYQKQKKEGKNPVFKPENLEINLFGISAWGANK
YKNSDKQIFLM
>Mature_491_residues
MKDFDSLIPGWFKEFVHVGTDLIWSQYLIGLLLTAGFFFTISSKFVQLRMLPEMFRALVERPETLEDGKKGISPFQAFAI
SAGSRVGTGNIAGVATAIVLGGPGAVFWMWVIAFIGAASAFIEATLAQVYKVHDKDGGFRGGPAYYITKGLNQKWLGIVF
AILITITFAFVFNTVQSNTIAESLNTQYNISPVITGIILAIVTAIIIFGGVRSIATLSSLIVPIMAIIYIGMVLVILLFN
LDQIVPMIGTIIKSAFGIEQVTGGAVGAAVLQGIKRGLFSNEAGMGSAPNAAATAAVPHPVKQGLIQSLGVFFDTMLVCT
ATAIMILLYSGLKFGDNAPQGVAVTQSALNEHLGSAGGIFLTIAVTLFAFSSVVGNYYYGQSNIEFLSTNRVILFIFRCL
VVVLVFVGAVVKTETVWNTADLFMGLMAIVNIISIIGLSNVAFALMKDYQKQKKEGKNPVFKPENLEINLFGISAWGANK
YKNSDKQIFLM

Specific function: Unknown

COG id: COG1115

COG function: function code E; Na+/alanine symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:alanine (SAF) symporter family [H]

Homologues:

Organism=Escherichia coli, GI1786188, Length=470, Percent_Identity=40.6382978723404, Blast_Score=335, Evalue=5e-93,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001463 [H]

Pfam domain/function: PF01235 Na_Ala_symp [H]

EC number: NA

Molecular weight: Translated: 52775; Mature: 52775

Theoretical pI: Translated: 9.32; Mature: 9.32

Prosite motif: PS00873 NA_ALANINE_SYMP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDFDSLIPGWFKEFVHVGTDLIWSQYLIGLLLTAGFFFTISSKFVQLRMLPEMFRALVE
CCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
RPETLEDGKKGISPFQAFAISAGSRVGTGNIAGVATAIVLGGPGAVFWMWVIAFIGAASA
CCCHHHHHHCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
FIEATLAQVYKVHDKDGGFRGGPAYYITKGLNQKWLGIVFAILITITFAFVFNTVQSNTI
HHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AESLNTQYNISPVITGIILAIVTAIIIFGGVRSIATLSSLIVPIMAIIYIGMVLVILLFN
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDQIVPMIGTIIKSAFGIEQVTGGAVGAAVLQGIKRGLFSNEAGMGSAPNAAATAAVPHP
HHHHHHHHHHHHHHHHCHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHH
VKQGLIQSLGVFFDTMLVCTATAIMILLYSGLKFGDNAPQGVAVTQSALNEHLGSAGGIF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCHH
LTIAVTLFAFSSVVGNYYYGQSNIEFLSTNRVILFIFRCLVVVLVFVGAVVKTETVWNTA
HHHHHHHHHHHHHHCCCEECCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLFMGLMAIVNIISIIGLSNVAFALMKDYQKQKKEGKNPVFKPENLEINLFGISAWGANK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEECCCCC
YKNSDKQIFLM
CCCCCCEEEEC
>Mature Secondary Structure
MKDFDSLIPGWFKEFVHVGTDLIWSQYLIGLLLTAGFFFTISSKFVQLRMLPEMFRALVE
CCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
RPETLEDGKKGISPFQAFAISAGSRVGTGNIAGVATAIVLGGPGAVFWMWVIAFIGAASA
CCCHHHHHHCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
FIEATLAQVYKVHDKDGGFRGGPAYYITKGLNQKWLGIVFAILITITFAFVFNTVQSNTI
HHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AESLNTQYNISPVITGIILAIVTAIIIFGGVRSIATLSSLIVPIMAIIYIGMVLVILLFN
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDQIVPMIGTIIKSAFGIEQVTGGAVGAAVLQGIKRGLFSNEAGMGSAPNAAATAAVPHP
HHHHHHHHHHHHHHHHCHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHH
VKQGLIQSLGVFFDTMLVCTATAIMILLYSGLKFGDNAPQGVAVTQSALNEHLGSAGGIF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCHH
LTIAVTLFAFSSVVGNYYYGQSNIEFLSTNRVILFIFRCLVVVLVFVGAVVKTETVWNTA
HHHHHHHHHHHHHHCCCEECCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLFMGLMAIVNIISIIGLSNVAFALMKDYQKQKKEGKNPVFKPENLEINLFGISAWGANK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEECCCCC
YKNSDKQIFLM
CCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; L-alanine [Periplasm] [C]

Specific reaction: Na (I) [Periplasm] + L-alanine [Periplasm] = Na (I) [Cytoplasm] + L-alanine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969507; 9384377; 7710280 [H]