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The map label for this gene is trpS

Identifier: 57650189

GI number: 57650189

Start: 1009158

End: 1010147

Strand: Reverse

Name: trpS

Synonym: SACOL1001

Alternate gene names: 57650189

Gene position: 1010147-1009158 (Counterclockwise)

Preceding gene: 57650194

Following gene: 57650177

Centisome position: 35.96

GC content: 34.65

Gene sequence:

>990_bases
ATGGAGACATTATTTTCAGGCATCCAACCTAGTGGAATTCCTACTATTGGAAATTATATTGGCGCACTAAAACAATTTGT
TGATGTGCAAAATGACTATGATTGTTATTTCTGTATCGTAGATCAACATGCAATTACAATGCCACAAGATCGTTTAAAAT
TACGTAAACAGACCAGACAATTAGCAGCGATTTATTTAGCTTCTGGTATAGATCCAGACAAAGCAACATTGTTCATACAA
TCTGAAGTCCCTGCACACGTACAAGCAGGATGGATGTTAACTACGATTGCTTCTGTTGGAGAATTAGAGCGTATGACGCA
ATACAAAGATAAAGCTCAGAAAGCAGTTGAAGGTATACCTGCTGGTCTATTAACATATCCACCTTTAATGGCAGCTGATA
TTGTTCTTTACAATACTAATATCGTTCCAGTTGGAGATGACCAAAAGCAGCATATCGAATTGACTCGTAACCTTGTAGAT
AGATTTAATAGTCGCTATAATGATGTGCTTGTGAAACCTGAAATTCGTATGCCTAAAGTTGGTGGACGTGTCATGAGTTT
ACAAGACCCAACAAGAAAAATGAGTAAGAGTGATGATAATGCTAAAAACTTCATTTCATTATTAGACGAGCCGAATGTTG
CAGCTAAAAAAATTAAAAGCGCAGTAACTGATTCAGATGGTATTATTAAATTTGATCGTGACAACAAGCCAGGTATAACA
AATTTAATTTCAATATACGCTGGATTAACAGACATGCCAATTAAAGATATTGAGGCAAAATATGAGGGCGAAGGTTATGG
TAAATTTAAAGGTGACCTTGCTGAAATAGTTAAAGCATTTTTAGTAGAATTCCAAGAAAAATACGAAAGTTTCTATAACT
CAGATAAACTTGATGATATTTTAGATCAAGGTAGAGATAAAGCACACAAAGTTTCATTTAAAACTGTCAAAAAAATGGAA
AAAGCGATGGGTTTAGGACGTAAGAGATAA

Upstream 100 bases:

>100_bases
TAGTAGTAAGTTATACGTATATTCTAACACATCTTACATTTTTAAGAAATACTGTTATAATGATAATTATTAAAATATTA
CTAAGAAAGTAGGCATTTAA

Downstream 100 bases:

>100_bases
AATAAAGAGGTACTAGAATTAACTAGTGCCTCTTTTATTATTTAACGTCTACCTCTAGGATTAAAAGCATCTTTAATCCC
TTCCCCTACAAAGTTTATAC

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
METLFSGIQPSGIPTIGNYIGALKQFVDVQNDYDCYFCIVDQHAITMPQDRLKLRKQTRQLAAIYLASGIDPDKATLFIQ
SEVPAHVQAGWMLTTIASVGELERMTQYKDKAQKAVEGIPAGLLTYPPLMAADIVLYNTNIVPVGDDQKQHIELTRNLVD
RFNSRYNDVLVKPEIRMPKVGGRVMSLQDPTRKMSKSDDNAKNFISLLDEPNVAAKKIKSAVTDSDGIIKFDRDNKPGIT
NLISIYAGLTDMPIKDIEAKYEGEGYGKFKGDLAEIVKAFLVEFQEKYESFYNSDKLDDILDQGRDKAHKVSFKTVKKME
KAMGLGRKR

Sequences:

>Translated_329_residues
METLFSGIQPSGIPTIGNYIGALKQFVDVQNDYDCYFCIVDQHAITMPQDRLKLRKQTRQLAAIYLASGIDPDKATLFIQ
SEVPAHVQAGWMLTTIASVGELERMTQYKDKAQKAVEGIPAGLLTYPPLMAADIVLYNTNIVPVGDDQKQHIELTRNLVD
RFNSRYNDVLVKPEIRMPKVGGRVMSLQDPTRKMSKSDDNAKNFISLLDEPNVAAKKIKSAVTDSDGIIKFDRDNKPGIT
NLISIYAGLTDMPIKDIEAKYEGEGYGKFKGDLAEIVKAFLVEFQEKYESFYNSDKLDDILDQGRDKAHKVSFKTVKKME
KAMGLGRKR
>Mature_329_residues
METLFSGIQPSGIPTIGNYIGALKQFVDVQNDYDCYFCIVDQHAITMPQDRLKLRKQTRQLAAIYLASGIDPDKATLFIQ
SEVPAHVQAGWMLTTIASVGELERMTQYKDKAQKAVEGIPAGLLTYPPLMAADIVLYNTNIVPVGDDQKQHIELTRNLVD
RFNSRYNDVLVKPEIRMPKVGGRVMSLQDPTRKMSKSDDNAKNFISLLDEPNVAAKKIKSAVTDSDGIIKFDRDNKPGIT
NLISIYAGLTDMPIKDIEAKYEGEGYGKFKGDLAEIVKAFLVEFQEKYESFYNSDKLDDILDQGRDKAHKVSFKTVKKME
KAMGLGRKR

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI7710154, Length=324, Percent_Identity=35.1851851851852, Blast_Score=224, Evalue=9e-59,
Organism=Homo sapiens, GI41352700, Length=172, Percent_Identity=45.3488372093023, Blast_Score=163, Evalue=2e-40,
Organism=Escherichia coli, GI1789786, Length=325, Percent_Identity=51.6923076923077, Blast_Score=351, Evalue=3e-98,
Organism=Caenorhabditis elegans, GI71982800, Length=328, Percent_Identity=33.2317073170732, Blast_Score=213, Evalue=8e-56,
Organism=Caenorhabditis elegans, GI71982793, Length=328, Percent_Identity=33.2317073170732, Blast_Score=213, Evalue=2e-55,
Organism=Saccharomyces cerevisiae, GI6320474, Length=344, Percent_Identity=37.2093023255814, Blast_Score=213, Evalue=4e-56,
Organism=Drosophila melanogaster, GI24666151, Length=326, Percent_Identity=38.0368098159509, Blast_Score=229, Evalue=3e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SYW_STAAC (Q5HH88)

Other databases:

- EMBL:   CP000046
- RefSeq:   YP_185869.1
- ProteinModelPortal:   Q5HH88
- SMR:   Q5HH88
- STRING:   Q5HH88
- EnsemblBacteria:   EBSTAT00000009948
- GeneID:   3236281
- GenomeReviews:   CP000046_GR
- KEGG:   sac:SACOL1001
- TIGR:   SACOL1001
- eggNOG:   COG0180
- GeneTree:   EBGT00050000024151
- HOGENOM:   HBG293263
- OMA:   NKPGVSN
- ProtClustDB:   PRK00927
- BioCyc:   SAUR93062:SACOL1001-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00140_B
- InterPro:   IPR001412
- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR10055
- PRINTS:   PR01039
- TIGRFAMs:   TIGR00233

Pfam domain/function: PF00579 tRNA-synt_1b

EC number: =6.1.1.2

Molecular weight: Translated: 36910; Mature: 36910

Theoretical pI: Translated: 8.15; Mature: 8.15

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: BINDING 196-196

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METLFSGIQPSGIPTIGNYIGALKQFVDVQNDYDCYFCIVDQHAITMPQDRLKLRKQTRQ
CCCHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHH
LAAIYLASGIDPDKATLFIQSEVPAHVQAGWMLTTIASVGELERMTQYKDKAQKAVEGIP
HHHHHHHCCCCCCCEEEEEECCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
AGLLTYPPLMAADIVLYNTNIVPVGDDQKQHIELTRNLVDRFNSRYNDVLVKPEIRMPKV
CCHHHCCCHHHHCEEEEECEEEECCCCHHHHHHHHHHHHHHHCCHHCCEEECCCCCCCCC
GGRVMSLQDPTRKMSKSDDNAKNFISLLDEPNVAAKKIKSAVTDSDGIIKFDRDNKPGIT
CCEEEECCCHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEECCCCCCCHH
NLISIYAGLTDMPIKDIEAKYEGEGYGKFKGDLAEIVKAFLVEFQEKYESFYNSDKLDDI
HHHHHHHCCCCCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
LDQGRDKAHKVSFKTVKKMEKAMGLGRKR
HHCCCCHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
METLFSGIQPSGIPTIGNYIGALKQFVDVQNDYDCYFCIVDQHAITMPQDRLKLRKQTRQ
CCCHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHH
LAAIYLASGIDPDKATLFIQSEVPAHVQAGWMLTTIASVGELERMTQYKDKAQKAVEGIP
HHHHHHHCCCCCCCEEEEEECCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
AGLLTYPPLMAADIVLYNTNIVPVGDDQKQHIELTRNLVDRFNSRYNDVLVKPEIRMPKV
CCHHHCCCHHHHCEEEEECEEEECCCCHHHHHHHHHHHHHHHCCHHCCEEECCCCCCCCC
GGRVMSLQDPTRKMSKSDDNAKNFISLLDEPNVAAKKIKSAVTDSDGIIKFDRDNKPGIT
CCEEEECCCHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEECCCCCCCHH
NLISIYAGLTDMPIKDIEAKYEGEGYGKFKGDLAEIVKAFLVEFQEKYESFYNSDKLDDI
HHHHHHHCCCCCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
LDQGRDKAHKVSFKTVKKMEKAMGLGRKR
HHCCCCHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA