Click here to switch to the map view.

The map label for this gene is pyrC [H]

Identifier: 57238067

GI number: 57238067

Start: 1244602

End: 1245780

Strand: Reverse

Name: pyrC [H]

Synonym: CJE1329

Alternate gene names: 57238067

Gene position: 1245780-1244602 (Counterclockwise)

Preceding gene: 57238068

Following gene: 57238065

Centisome position: 70.07

GC content: 29.18

Gene sequence:

>1179_bases
ATGATAATTAAAAATGCAAAAATTTATGGAGATTCTTTACAAGATATAGAGATTAAAGAAGGAAAAATTACCAATATTGG
TTCTAATTTACAAGGCGAAGAAATTTTAGATGCTAAAGGTATGACTTTACTTCCATCTTTTGTGGATTTGTGTGTGAGTT
TAAAAAACGATAAATTTTCTTTAGCTAATTTAGAGCTTTTAGAAAATGAGTGTCTAAAAGGAGGAATTTCTAGTATAGTT
TTGCGTGATTGCATGGATTTTGATGAAGAAAGTTTTGCTTTATTTTTACAAAATTTAGCTCAAAGAAAGATGCAAATTTT
TTCAAGTGTGCGGGTTAAGGATACAAACGGCAAGCTTAAAAATTTAGCCACTCTTTTAAATAAAGGTGCTTGTGCTCTAG
AACTTGACAGCTCTTTAGATGCAAATACTTTAAAAGTAAGTTCACAATATGCTTTTATGAAAGACTCTCCAATTTTTGTG
CGTTGTTATGATAAGGATTTTGATGATAATGGAGTGATGAATGATTGTGAAATGAGTTTTGAGCTAGGGCTTATAGGCAT
GAGTAAAATCGCTGAAACTAGCCAGATAGCTAAAATGAAAGAATTGGCTAAATTTTATAAAAATAAAGTTATTTTTGATC
TTTTAAGTTTGAAAGATTCTTTAGTATTATTAGATGAAAAGGATTTAAAACTTGTAAGCATTCATCATCTTATCAAAGAT
GATAGTGCTTGTGAAGATTTTAATACGGCTGCGAAACTTATGCCACCTTTAAGAAGCAAAGAAGATGTTTTGGCTTTAAG
AGAGGCTTTAAAAGAAGGAAAGATTAGCTTTTTAACTTCCCTGCATAGTGCAAAATCAATTTCTTTAAAAGATTTAGCTT
TTGATGAAGCGGCTTTTGGAATTCATAGCGTATGCGAATTTATAAGTCTTTGTTATACTTTTTTAATCAAAGAAGGATTT
TTAAATTGGCAAGAGCTTTGTCGATTTACAAGTAAAAATCCTAGTGAATTTTTAGGTTTAAATAGTGGAGTTATAGAAGT
TGGCAAAGAAGCTAATCTAGTTCTTTTTGATGAGAATGAAGAAATTTTTGCTCCAAAAAGTTCTCTTTATTCTGAGGATA
AACTTTTTGGAAAGATTAAGATGCATATAATTAAAGGAAAAAATATTTTAGAAAAATAA

Upstream 100 bases:

>100_bases
TTATACACCTATTGTAAATGAAGTAGTGGCAATTTTTAAGGGTAAAAGCGTGCAAGAAGCAACGCAGAATTTATTAAAGC
AAAATGATTAAGGAAAAATC

Downstream 100 bases:

>100_bases
GCTTTACTTAAATTCCTAAAGATAGTTTAAATCCTAAAAATACAAGTGCTGCCATAATACCAGCGGCTGGTAAAGTGATA
ATCCAAGCCAATCCTATAGG

Product: dihydroorotase

Products: NA

Alternate protein names: DHOase [H]

Number of amino acids: Translated: 392; Mature: 392

Protein sequence:

>392_residues
MIIKNAKIYGDSLQDIEIKEGKITNIGSNLQGEEILDAKGMTLLPSFVDLCVSLKNDKFSLANLELLENECLKGGISSIV
LRDCMDFDEESFALFLQNLAQRKMQIFSSVRVKDTNGKLKNLATLLNKGACALELDSSLDANTLKVSSQYAFMKDSPIFV
RCYDKDFDDNGVMNDCEMSFELGLIGMSKIAETSQIAKMKELAKFYKNKVIFDLLSLKDSLVLLDEKDLKLVSIHHLIKD
DSACEDFNTAAKLMPPLRSKEDVLALREALKEGKISFLTSLHSAKSISLKDLAFDEAAFGIHSVCEFISLCYTFLIKEGF
LNWQELCRFTSKNPSEFLGLNSGVIEVGKEANLVLFDENEEIFAPKSSLYSEDKLFGKIKMHIIKGKNILEK

Sequences:

>Translated_392_residues
MIIKNAKIYGDSLQDIEIKEGKITNIGSNLQGEEILDAKGMTLLPSFVDLCVSLKNDKFSLANLELLENECLKGGISSIV
LRDCMDFDEESFALFLQNLAQRKMQIFSSVRVKDTNGKLKNLATLLNKGACALELDSSLDANTLKVSSQYAFMKDSPIFV
RCYDKDFDDNGVMNDCEMSFELGLIGMSKIAETSQIAKMKELAKFYKNKVIFDLLSLKDSLVLLDEKDLKLVSIHHLIKD
DSACEDFNTAAKLMPPLRSKEDVLALREALKEGKISFLTSLHSAKSISLKDLAFDEAAFGIHSVCEFISLCYTFLIKEGF
LNWQELCRFTSKNPSEFLGLNSGVIEVGKEANLVLFDENEEIFAPKSSLYSEDKLFGKIKMHIIKGKNILEK
>Mature_392_residues
MIIKNAKIYGDSLQDIEIKEGKITNIGSNLQGEEILDAKGMTLLPSFVDLCVSLKNDKFSLANLELLENECLKGGISSIV
LRDCMDFDEESFALFLQNLAQRKMQIFSSVRVKDTNGKLKNLATLLNKGACALELDSSLDANTLKVSSQYAFMKDSPIFV
RCYDKDFDDNGVMNDCEMSFELGLIGMSKIAETSQIAKMKELAKFYKNKVIFDLLSLKDSLVLLDEKDLKLVSIHHLIKD
DSACEDFNTAAKLMPPLRSKEDVLALREALKEGKISFLTSLHSAKSISLKDLAFDEAAFGIHSVCEFISLCYTFLIKEGF
LNWQELCRFTSKNPSEFLGLNSGVIEVGKEANLVLFDENEEIFAPKSSLYSEDKLFGKIKMHIIKGKNILEK

Specific function: Involved In The Anaerobic Utilization Of Allantoin. [C]

COG id: COG0044

COG function: function code F; Dihydroorotase and related cyclic amidohydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHOase family. Type 2 subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR004722
- InterPro:   IPR002195
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.2.3 [H]

Molecular weight: Translated: 43894; Mature: 43894

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS00018 EF_HAND_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIKNAKIYGDSLQDIEIKEGKITNIGSNLQGEEILDAKGMTLLPSFVDLCVSLKNDKFS
CEECCCEEECCCCCCEEECCCEEECCCCCCCCCHHHCCCCCCHHHHHHHHHHHCCCCCEE
LANLELLENECLKGGISSIVLRDCMDFDEESFALFLQNLAQRKMQIFSSVRVKDTNGKLK
HHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCEEECCCCHHH
NLATLLNKGACALELDSSLDANTLKVSSQYAFMKDSPIFVRCYDKDFDDNGVMNDCEMSF
HHHHHHCCCCEEEEECCCCCCCEEEECCCEEEECCCCEEEEEECCCCCCCCCCCCCCCEE
ELGLIGMSKIAETSQIAKMKELAKFYKNKVIFDLLSLKDSLVLLDEKDLKLVSIHHLIKD
EECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHCC
DSACEDFNTAAKLMPPLRSKEDVLALREALKEGKISFLTSLHSAKSISLKDLAFDEAAFG
CCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHH
IHSVCEFISLCYTFLIKEGFLNWQELCRFTSKNPSEFLGLNSGVIEVGKEANLVLFDENE
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHCCCCCCEEECCCCCEEEECCCC
EIFAPKSSLYSEDKLFGKIKMHIIKGKNILEK
CEECCCHHHCCHHHHHEEEEEEEEECCHHHCC
>Mature Secondary Structure
MIIKNAKIYGDSLQDIEIKEGKITNIGSNLQGEEILDAKGMTLLPSFVDLCVSLKNDKFS
CEECCCEEECCCCCCEEECCCEEECCCCCCCCCHHHCCCCCCHHHHHHHHHHHCCCCCEE
LANLELLENECLKGGISSIVLRDCMDFDEESFALFLQNLAQRKMQIFSSVRVKDTNGKLK
HHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCEEECCCCHHH
NLATLLNKGACALELDSSLDANTLKVSSQYAFMKDSPIFVRCYDKDFDDNGVMNDCEMSF
HHHHHHCCCCEEEEECCCCCCCEEEECCCEEEECCCCEEEEEECCCCCCCCCCCCCCCEE
ELGLIGMSKIAETSQIAKMKELAKFYKNKVIFDLLSLKDSLVLLDEKDLKLVSIHHLIKD
EECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHCC
DSACEDFNTAAKLMPPLRSKEDVLALREALKEGKISFLTSLHSAKSISLKDLAFDEAAFG
CCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHH
IHSVCEFISLCYTFLIKEGFLNWQELCRFTSKNPSEFLGLNSGVIEVGKEANLVLFDENE
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHCCCCCCEEECCCCCEEEECCCC
EIFAPKSSLYSEDKLFGKIKMHIIKGKNILEK
CEECCCHHHCCHHHHHEEEEEEEEECCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA