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The map label for this gene is argS [H]

Identifier: 57238047

GI number: 57238047

Start: 1222934

End: 1224526

Strand: Reverse

Name: argS [H]

Synonym: CJE1309

Alternate gene names: 57238047

Gene position: 1224526-1222934 (Counterclockwise)

Preceding gene: 57238048

Following gene: 57238044

Centisome position: 68.88

GC content: 31.51

Gene sequence:

>1593_bases
TTGAAAAGTATTATTTTTAATGAAATTAAAAAGATTTTAGAGTGTGATTTTGCGCTTGAAAATCCAAAGGATAAAAATTT
AGCACATTTTGCTACCCCTTTGGCTTTTTCACTGGCTAAGGAATTAAAAAAATCCCCTATGTTGATCGCTAGCGACTTAG
CGAGCAAATTTCAAAATCATGATTGTTTTGAATCAGTTGAAGCTGTAAATGGGTATTTAAATTTTAGAATTTCCAAAACT
TTTTTAAATGAACTTGCAAATCAGGCTTTAACAAATCCAAATGATTTTACTAAAGGAGAAAAAAAACAAGAAAGTTTTTT
GCTTGAATATGTGAGTGCAAATCCTACTGGGCCTTTACACATAGGACATGCAAGAGGCGCTGTTTTTGGAGACACCTTAA
CAAGACTTGCAAGACATTTGGGCTATAAATTTAATACAGAATACTATGTCAATGATGCGGGTAATCAAATTTATTTACTA
GGGCTTTCTATTTTACTAAGTGTGAAAGAAAGTATACTTCATGAAAATGTTGAATATCCAGAGCAATATTACAAAGGCGA
GTATATAGCGGATTTAGCAAAAGAAGCTTTTGAAAAATTTGGTAAAGAATTTTTTAGCCAAGAAAATATCCCTAGTTTGG
CTGATTGGGCAAAAGATAAAATGCTTGTTTTGATTAAACAAAATTTAGAACAAGCAAAGATTAAAATTGACAGCTATGTA
AGCGAAAGATCGTATTATGATGCTTTAAATGCAACTTTAGAATCTTTAAAAGAGCATAAAGGAATTTACGAGCAAGAAGG
TAAAATTTGGCTTGCTTCTTCGCAAAAAGGCGATGAAAAAGATAGGGTAATTATCCGTGAAGATGGACGCGGGACTTATT
TGGCAGCAGATATTGTTTATCATAAAGATAAAATGAGTCGTGGTTATGGAAAGTGTATTAATATTTGGGGAGCAGATCAT
CATGGTTATATCCCTAGAATGAAAGCTGCGATGGAATTTTTGGGATTTGACTCTAATAATCTTGAGATTATTTTAGCACA
AATGGTTTCCCTACTTAAAGATGGAGAACCTTATAAAATGAGTAAAAGAGCAGGAAATTTTATCTTGATGAGCGATGTGG
TTAATGAGATAGGAAGTGATGCTTTGCGTTATATCTTTTTGAGCAAAAAATGCGATACGCATTTGGAATTTGATATTAGT
GATTTGCAAAAAGAAGATAGTTCTAATCCTGTGTATTATATCAACTATGCACACGCTAGAATTCATCAAGTATTTGCTAA
AGCTGGTAAAAAAATCGATGATGTAATGAAAGCTGATTTACAAAGTTTAAATCAAGATGGCGTAAATTTGCTTTTTGAAG
CTTTGAATTTAAAGGCTGTTTTAAACGATGCTTTTGAGGCTAGAGCTTTGCAAAAAATTCCTGATTATCTTAAAAATTTA
GCTGCAAATTTTCATAAATTCTACAATGAAAATAAAGTTGTAGGCTCTGCAAATGAAAATGATTTGCTTAAATTATTTTC
TTTGGTTGCTCTTAGTATTAAAACCGCATTTTCTTTAATGGGTATTGAAGCAAAAAACAAAATGGAACATTAA

Upstream 100 bases:

>100_bases
CAAAAAATACTCAAAAAATAGAAGAAAACAAAAACACAACTAATAATACAAATGCTGATGCAAGTATAGACGAAACAAAA
AAAGCTTAAGGTTTAGTCTT

Downstream 100 bases:

>100_bases
AACCGCATTTTGCTGTTTTAATAATTTAGCAAAAATACTGCTATTATTACGATAATGATACCTAAAATTCCTATTTTGTT
TAATTTTTCTTTATATAAAA

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS [H]

Number of amino acids: Translated: 530; Mature: 530

Protein sequence:

>530_residues
MKSIIFNEIKKILECDFALENPKDKNLAHFATPLAFSLAKELKKSPMLIASDLASKFQNHDCFESVEAVNGYLNFRISKT
FLNELANQALTNPNDFTKGEKKQESFLLEYVSANPTGPLHIGHARGAVFGDTLTRLARHLGYKFNTEYYVNDAGNQIYLL
GLSILLSVKESILHENVEYPEQYYKGEYIADLAKEAFEKFGKEFFSQENIPSLADWAKDKMLVLIKQNLEQAKIKIDSYV
SERSYYDALNATLESLKEHKGIYEQEGKIWLASSQKGDEKDRVIIREDGRGTYLAADIVYHKDKMSRGYGKCINIWGADH
HGYIPRMKAAMEFLGFDSNNLEIILAQMVSLLKDGEPYKMSKRAGNFILMSDVVNEIGSDALRYIFLSKKCDTHLEFDIS
DLQKEDSSNPVYYINYAHARIHQVFAKAGKKIDDVMKADLQSLNQDGVNLLFEALNLKAVLNDAFEARALQKIPDYLKNL
AANFHKFYNENKVVGSANENDLLKLFSLVALSIKTAFSLMGIEAKNKMEH

Sequences:

>Translated_530_residues
MKSIIFNEIKKILECDFALENPKDKNLAHFATPLAFSLAKELKKSPMLIASDLASKFQNHDCFESVEAVNGYLNFRISKT
FLNELANQALTNPNDFTKGEKKQESFLLEYVSANPTGPLHIGHARGAVFGDTLTRLARHLGYKFNTEYYVNDAGNQIYLL
GLSILLSVKESILHENVEYPEQYYKGEYIADLAKEAFEKFGKEFFSQENIPSLADWAKDKMLVLIKQNLEQAKIKIDSYV
SERSYYDALNATLESLKEHKGIYEQEGKIWLASSQKGDEKDRVIIREDGRGTYLAADIVYHKDKMSRGYGKCINIWGADH
HGYIPRMKAAMEFLGFDSNNLEIILAQMVSLLKDGEPYKMSKRAGNFILMSDVVNEIGSDALRYIFLSKKCDTHLEFDIS
DLQKEDSSNPVYYINYAHARIHQVFAKAGKKIDDVMKADLQSLNQDGVNLLFEALNLKAVLNDAFEARALQKIPDYLKNL
AANFHKFYNENKVVGSANENDLLKLFSLVALSIKTAFSLMGIEAKNKMEH
>Mature_530_residues
MKSIIFNEIKKILECDFALENPKDKNLAHFATPLAFSLAKELKKSPMLIASDLASKFQNHDCFESVEAVNGYLNFRISKT
FLNELANQALTNPNDFTKGEKKQESFLLEYVSANPTGPLHIGHARGAVFGDTLTRLARHLGYKFNTEYYVNDAGNQIYLL
GLSILLSVKESILHENVEYPEQYYKGEYIADLAKEAFEKFGKEFFSQENIPSLADWAKDKMLVLIKQNLEQAKIKIDSYV
SERSYYDALNATLESLKEHKGIYEQEGKIWLASSQKGDEKDRVIIREDGRGTYLAADIVYHKDKMSRGYGKCINIWGADH
HGYIPRMKAAMEFLGFDSNNLEIILAQMVSLLKDGEPYKMSKRAGNFILMSDVVNEIGSDALRYIFLSKKCDTHLEFDIS
DLQKEDSSNPVYYINYAHARIHQVFAKAGKKIDDVMKADLQSLNQDGVNLLFEALNLKAVLNDAFEARALQKIPDYLKNL
AANFHKFYNENKVVGSANENDLLKLFSLVALSIKTAFSLMGIEAKNKMEH

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI15149476, Length=557, Percent_Identity=22.262118491921, Blast_Score=70, Evalue=6e-12,
Organism=Homo sapiens, GI197100773, Length=535, Percent_Identity=22.9906542056075, Blast_Score=67, Evalue=5e-11,
Organism=Escherichia coli, GI1788184, Length=557, Percent_Identity=23.3393177737882, Blast_Score=97, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6321883, Length=555, Percent_Identity=22.1621621621622, Blast_Score=79, Evalue=2e-15,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d [H]

EC number: =6.1.1.19 [H]

Molecular weight: Translated: 60160; Mature: 60160

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSIIFNEIKKILECDFALENPKDKNLAHFATPLAFSLAKELKKSPMLIASDLASKFQNH
CCCHHHHHHHHHHHCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCC
DCFESVEAVNGYLNFRISKTFLNELANQALTNPNDFTKGEKKQESFLLEYVSANPTGPLH
HHHHHHHHHHHHHEEEEHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEE
IGHARGAVFGDTLTRLARHLGYKFNTEYYVNDAGNQIYLLGLSILLSVKESILHENVEYP
ECCCCCCHHHHHHHHHHHHCCCEECCEEEEECCCCEEEEHHHHHHHHHHHHHHHCCCCCC
EQYYKGEYIADLAKEAFEKFGKEFFSQENIPSLADWAKDKMLVLIKQNLEQAKIKIDSYV
HHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCEEHHHHHCHHHHHHHHHHHH
SERSYYDALNATLESLKEHKGIYEQEGKIWLASSQKGDEKDRVIIREDGRGTYLAADIVY
HHHHHHHHHHHHHHHHHHHCCCEECCCCEEEECCCCCCCCCEEEEEECCCCCEEEEHHHH
HKDKMSRGYGKCINIWGADHHGYIPRMKAAMEFLGFDSNNLEIILAQMVSLLKDGEPYKM
HHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCH
SKRAGNFILMSDVVNEIGSDALRYIFLSKKCDTHLEFDISDLQKEDSSNPVYYINYAHAR
HHCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCCEECHHHHHCCCCCCCEEEEEHHHHH
IHQVFAKAGKKIDDVMKADLQSLNQDGVNLLFEALNLKAVLNDAFEARALQKIPDYLKNL
HHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AANFHKFYNENKVVGSANENDLLKLFSLVALSIKTAFSLMGIEAKNKMEH
HHHHHHHHCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCC
>Mature Secondary Structure
MKSIIFNEIKKILECDFALENPKDKNLAHFATPLAFSLAKELKKSPMLIASDLASKFQNH
CCCHHHHHHHHHHHCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCC
DCFESVEAVNGYLNFRISKTFLNELANQALTNPNDFTKGEKKQESFLLEYVSANPTGPLH
HHHHHHHHHHHHHEEEEHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEE
IGHARGAVFGDTLTRLARHLGYKFNTEYYVNDAGNQIYLLGLSILLSVKESILHENVEYP
ECCCCCCHHHHHHHHHHHHCCCEECCEEEEECCCCEEEEHHHHHHHHHHHHHHHCCCCCC
EQYYKGEYIADLAKEAFEKFGKEFFSQENIPSLADWAKDKMLVLIKQNLEQAKIKIDSYV
HHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCEEHHHHHCHHHHHHHHHHHH
SERSYYDALNATLESLKEHKGIYEQEGKIWLASSQKGDEKDRVIIREDGRGTYLAADIVY
HHHHHHHHHHHHHHHHHHHCCCEECCCCEEEECCCCCCCCCEEEEEECCCCCEEEEHHHH
HKDKMSRGYGKCINIWGADHHGYIPRMKAAMEFLGFDSNNLEIILAQMVSLLKDGEPYKM
HHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCH
SKRAGNFILMSDVVNEIGSDALRYIFLSKKCDTHLEFDISDLQKEDSSNPVYYINYAHAR
HHCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCCEECHHHHHCCCCCCCEEEEEHHHHH
IHQVFAKAGKKIDDVMKADLQSLNQDGVNLLFEALNLKAVLNDAFEARALQKIPDYLKNL
HHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AANFHKFYNENKVVGSANENDLLKLFSLVALSIKTAFSLMGIEAKNKMEH
HHHHHHHHCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA