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The map label for this gene is galE [H]

Identifier: 57238012

GI number: 57238012

Start: 1190638

End: 1191624

Strand: Reverse

Name: galE [H]

Synonym: CJE1273

Alternate gene names: 57238012

Gene position: 1191624-1190638 (Counterclockwise)

Preceding gene: 57238013

Following gene: 57238011

Centisome position: 67.03

GC content: 33.94

Gene sequence:

>987_bases
ATGAAAATTCTTATTAGCGGTGGTGCAGGTTATATAGGTTCTCATACTTTAAGACAATTTTTAAAAACAGATCATGAAAT
TTGTGTTTTAGATAATCTTTCTAAGGGTTCTAAAATCGCAATAGAAGATTTGCAAAAAATAAGAGCTTTTAAATTTTTCG
AACAAGATTTAAGTGATTTTCAAGGCGTAAAAGCATTGTTTGAGAGAGAAAAATTTGACGCTATTGTGCATTTTGCAGCA
AGCATTGAAGTTTTTGAAAGTATGCAAAATCCTTTAAAATATTATATGAACAACACTGTTAATACGACAAATCTCATCGA
AACTTGTTTGCAAACTGGAGTAAATAAATTTATATTTTCTTCAACGGCAGCCACTTATGGCGAACCACAAACTCCTGTTG
TGAGCGAAACAAGCCCTTTGGCACCTATTAATCCTTATGGGCGTAGTAAGCTTATGAGTGAAGAGGTTTTGCGTGATGCA
AGTATGGCAAATCCTGAATTTAAGCATTGTATTTTAAGATATTTTAATGTTGCAGGTGCTTGTATGGATTATACTTTAGG
ACAACGCTATCCAAAAGCAACATTACTCATAAAAGTTGCAGCTGAATGTGCCGCAGGAAAACGTGATAAACTTTTCATAT
TTGGCGATGATTATGATACAAAAGATGGTACTTGCATAAGAGATTTTATCCATGTAGATGATATTTCAAGTGCGCATTTA
GCGACTTTGGATTATTTACAAGAGAATGAAAGTAATGTTTTTAATGTAGGTTATGGGCATGGTTTTAGTGTCAAAGAAGT
GATTGAAGCGATGAAAAAAGTTAGTGGAGTGGATTTTAAAGTAGAACTTGCCCCACGCCGTGCAGGTGATCCTAGTGTGT
TGATTTCTGATGCAAGTAAAATCAGAAATCTTACTTCTTGGCAGCCTAAATATGATGATTTAGAGCTTATTTGCAAATCT
GCTTTTGATTGGGAAAAACAGTGTTAA

Upstream 100 bases:

>100_bases
GCAAAAGCTTGTGAGAGTGAAATTTCAAAAGTTCAATCTTAAGTATTTAAGAAAATATATTAAAATTTATTTTTGACATT
TTTTAAAAAAAGGAATGATG

Downstream 100 bases:

>100_bases
AAAAACTTTTTTTTATTTTAAGTAAGGAAGATAAAAATTTTTTATTTTTTTTGCTTGTTTTTTCAGTATTTGTTTCTTTT
ATAGAAACTTTTGCGATTTC

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 328; Mature: 328

Protein sequence:

>328_residues
MKILISGGAGYIGSHTLRQFLKTDHEICVLDNLSKGSKIAIEDLQKIRAFKFFEQDLSDFQGVKALFEREKFDAIVHFAA
SIEVFESMQNPLKYYMNNTVNTTNLIETCLQTGVNKFIFSSTAATYGEPQTPVVSETSPLAPINPYGRSKLMSEEVLRDA
SMANPEFKHCILRYFNVAGACMDYTLGQRYPKATLLIKVAAECAAGKRDKLFIFGDDYDTKDGTCIRDFIHVDDISSAHL
ATLDYLQENESNVFNVGYGHGFSVKEVIEAMKKVSGVDFKVELAPRRAGDPSVLISDASKIRNLTSWQPKYDDLELICKS
AFDWEKQC

Sequences:

>Translated_328_residues
MKILISGGAGYIGSHTLRQFLKTDHEICVLDNLSKGSKIAIEDLQKIRAFKFFEQDLSDFQGVKALFEREKFDAIVHFAA
SIEVFESMQNPLKYYMNNTVNTTNLIETCLQTGVNKFIFSSTAATYGEPQTPVVSETSPLAPINPYGRSKLMSEEVLRDA
SMANPEFKHCILRYFNVAGACMDYTLGQRYPKATLLIKVAAECAAGKRDKLFIFGDDYDTKDGTCIRDFIHVDDISSAHL
ATLDYLQENESNVFNVGYGHGFSVKEVIEAMKKVSGVDFKVELAPRRAGDPSVLISDASKIRNLTSWQPKYDDLELICKS
AFDWEKQC
>Mature_328_residues
MKILISGGAGYIGSHTLRQFLKTDHEICVLDNLSKGSKIAIEDLQKIRAFKFFEQDLSDFQGVKALFEREKFDAIVHFAA
SIEVFESMQNPLKYYMNNTVNTTNLIETCLQTGVNKFIFSSTAATYGEPQTPVVSETSPLAPINPYGRSKLMSEEVLRDA
SMANPEFKHCILRYFNVAGACMDYTLGQRYPKATLLIKVAAECAAGKRDKLFIFGDDYDTKDGTCIRDFIHVDDISSAHL
ATLDYLQENESNVFNVGYGHGFSVKEVIEAMKKVSGVDFKVELAPRRAGDPSVLISDASKIRNLTSWQPKYDDLELICKS
AFDWEKQC

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=338, Percent_Identity=36.094674556213, Blast_Score=222, Evalue=5e-58,
Organism=Homo sapiens, GI56118217, Length=338, Percent_Identity=36.094674556213, Blast_Score=222, Evalue=5e-58,
Organism=Homo sapiens, GI189083684, Length=338, Percent_Identity=36.094674556213, Blast_Score=222, Evalue=5e-58,
Organism=Homo sapiens, GI7657641, Length=341, Percent_Identity=27.2727272727273, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI42516563, Length=313, Percent_Identity=24.9201277955272, Blast_Score=94, Evalue=2e-19,
Organism=Escherichia coli, GI1786974, Length=333, Percent_Identity=35.7357357357357, Blast_Score=220, Evalue=9e-59,
Organism=Escherichia coli, GI1790049, Length=275, Percent_Identity=28.7272727272727, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1788353, Length=358, Percent_Identity=24.8603351955307, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI48994969, Length=339, Percent_Identity=26.2536873156342, Blast_Score=77, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71982035, Length=342, Percent_Identity=35.3801169590643, Blast_Score=224, Evalue=7e-59,
Organism=Caenorhabditis elegans, GI71982038, Length=344, Percent_Identity=35.1744186046512, Blast_Score=223, Evalue=1e-58,
Organism=Caenorhabditis elegans, GI17568069, Length=326, Percent_Identity=27.9141104294479, Blast_Score=82, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17539532, Length=315, Percent_Identity=24.1269841269841, Blast_Score=72, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6319493, Length=338, Percent_Identity=38.7573964497041, Blast_Score=232, Evalue=5e-62,
Organism=Saccharomyces cerevisiae, GI6321437, Length=182, Percent_Identity=25.2747252747253, Blast_Score=66, Evalue=9e-12,
Organism=Drosophila melanogaster, GI19923002, Length=338, Percent_Identity=34.6153846153846, Blast_Score=211, Evalue=7e-55,
Organism=Drosophila melanogaster, GI21356223, Length=314, Percent_Identity=26.1146496815287, Blast_Score=95, Evalue=8e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 36776; Mature: 36776

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILISGGAGYIGSHTLRQFLKTDHEICVLDNLSKGSKIAIEDLQKIRAFKFFEQDLSDF
CEEEEECCCCCCHHHHHHHHHHCCCCEEEEECCCCCCEEHHHHHHHHHHHHHHHHHHHHH
QGVKALFEREKFDAIVHFAASIEVFESMQNPLKYYMNNTVNTTNLIETCLQTGVNKFIFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCHHHHHHH
STAATYGEPQTPVVSETSPLAPINPYGRSKLMSEEVLRDASMANPEFKHCILRYFNVAGA
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
CMDYTLGQRYPKATLLIKVAAECAAGKRDKLFIFGDDYDTKDGTCIRDFIHVDDISSAHL
HHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHHHHCCCCCHHH
ATLDYLQENESNVFNVGYGHGFSVKEVIEAMKKVSGVDFKVELAPRRAGDPSVLISDASK
HHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCEEECCHHH
IRNLTSWQPKYDDLELICKSAFDWEKQC
HHHCCCCCCCCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKILISGGAGYIGSHTLRQFLKTDHEICVLDNLSKGSKIAIEDLQKIRAFKFFEQDLSDF
CEEEEECCCCCCHHHHHHHHHHCCCCEEEEECCCCCCEEHHHHHHHHHHHHHHHHHHHHH
QGVKALFEREKFDAIVHFAASIEVFESMQNPLKYYMNNTVNTTNLIETCLQTGVNKFIFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCHHHHHHH
STAATYGEPQTPVVSETSPLAPINPYGRSKLMSEEVLRDASMANPEFKHCILRYFNVAGA
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
CMDYTLGQRYPKATLLIKVAAECAAGKRDKLFIFGDDYDTKDGTCIRDFIHVDDISSAHL
HHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHHHHCCCCCHHH
ATLDYLQENESNVFNVGYGHGFSVKEVIEAMKKVSGVDFKVELAPRRAGDPSVLISDASK
HHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCEEECCHHH
IRNLTSWQPKYDDLELICKSAFDWEKQC
HHHCCCCCCCCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9603808 [H]