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The map label for this gene is argF [H]

Identifier: 57237819

GI number: 57237819

Start: 1002740

End: 1003660

Strand: Reverse

Name: argF [H]

Synonym: CJE1074

Alternate gene names: 57237819

Gene position: 1003660-1002740 (Counterclockwise)

Preceding gene: 57237820

Following gene: 57237818

Centisome position: 56.45

GC content: 34.96

Gene sequence:

>921_bases
ATGAAACATTTTTTAACTTTAAGAGATTTTTCTAAGGAGGAAATTTTAAGCCTTGTAAATCATGCTAGCGAGCTTAAAAA
AGAGCCTAAAAAACTTTTACAAGATAAAACTTTAGCAATGATTTTTGAGAAAAACTCTACAAGAACAAGAATGGCCTTTG
AATTAGCCATAACAGAGCTTGGCGGAAAGGCTTTATTTTTAAGCAGCAATGATTTACAACTTAGTCGTGGCGAGCCTGTA
AAGGATACAGCTAGGGTGATAGGGGCGATGGTTGATTTTGTGATGATGAGAGTCAATAAACATGAAACTTTACTCGAATT
TGCAAGATATTCTAAAGCCCCTGTGATCAATGCTTTAAGCGAGCTTTATCACCCTACTCAGGTTTTAGGAGATTTGCTTA
CTATCAAAGAATGGAATAAGATGCAAAATGGTATAGCAAAAGTTGCTTTTATCGGAGATAGTAACAATATGTGCAATTCT
TGGCTTATTGCGGCTGCGATTTTGGGTTTTGAATTTAGTATAGCTATACCAAAAAACTATAAAATTAGCCCTGAAATTTG
GGAATTTGCTATGAAACAGGCTTTGATTTCAGGAGCTAAAATTTCCTTAAGTCATGATAGATTTGAAGCCTTAAAGGATA
AAGATGTAGTCATTACCGATACTTGGGTTTCTATGGGTGAAGAGAATGAAAAAGAACGCAAGATTAAAGAATTTGAAGGA
TTTATGATTGATGAAAAGGCTATGAGCGTTGCCAATAAAGACGCGATATTGCTTCATTGTTTGCCTGCTTATAGGGGTTA
TGAAGTGAGTGAAGAAATTTTTGAAAAACATGCAGATGTGATTTTTGAAGAAGCAAGAAATCGCCTTTATGTGGTAAAAG
CCTTGCTTTGCTTTTTGGATAATCAGAGAGGAAGAGAATGA

Upstream 100 bases:

>100_bases
AAGTTTTGTATGAAACTATGATAGCTTTTAAAAGAGCAGGGGCAAAGCTTATCATCACTTATCATGCCAAAGAATTAGCT
AAAATGTTAAAAGGAGAAAA

Downstream 100 bases:

>100_bases
AAGAGCTAGAAAAGTATAACACTTGCTTAAAACGCATTGATGAATTTAGTCAAAATCTAGGAATAAAGAAAAAAGATAGA
ACGATTTTTAAAATGAAGCA

Product: ornithine carbamoyltransferase

Products: NA

Alternate protein names: OTCase [H]

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MKHFLTLRDFSKEEILSLVNHASELKKEPKKLLQDKTLAMIFEKNSTRTRMAFELAITELGGKALFLSSNDLQLSRGEPV
KDTARVIGAMVDFVMMRVNKHETLLEFARYSKAPVINALSELYHPTQVLGDLLTIKEWNKMQNGIAKVAFIGDSNNMCNS
WLIAAAILGFEFSIAIPKNYKISPEIWEFAMKQALISGAKISLSHDRFEALKDKDVVITDTWVSMGEENEKERKIKEFEG
FMIDEKAMSVANKDAILLHCLPAYRGYEVSEEIFEKHADVIFEEARNRLYVVKALLCFLDNQRGRE

Sequences:

>Translated_306_residues
MKHFLTLRDFSKEEILSLVNHASELKKEPKKLLQDKTLAMIFEKNSTRTRMAFELAITELGGKALFLSSNDLQLSRGEPV
KDTARVIGAMVDFVMMRVNKHETLLEFARYSKAPVINALSELYHPTQVLGDLLTIKEWNKMQNGIAKVAFIGDSNNMCNS
WLIAAAILGFEFSIAIPKNYKISPEIWEFAMKQALISGAKISLSHDRFEALKDKDVVITDTWVSMGEENEKERKIKEFEG
FMIDEKAMSVANKDAILLHCLPAYRGYEVSEEIFEKHADVIFEEARNRLYVVKALLCFLDNQRGRE
>Mature_306_residues
MKHFLTLRDFSKEEILSLVNHASELKKEPKKLLQDKTLAMIFEKNSTRTRMAFELAITELGGKALFLSSNDLQLSRGEPV
KDTARVIGAMVDFVMMRVNKHETLLEFARYSKAPVINALSELYHPTQVLGDLLTIKEWNKMQNGIAKVAFIGDSNNMCNS
WLIAAAILGFEFSIAIPKNYKISPEIWEFAMKQALISGAKISLSHDRFEALKDKDVVITDTWVSMGEENEKERKIKEFEG
FMIDEKAMSVANKDAILLHCLPAYRGYEVSEEIFEKHADVIFEEARNRLYVVKALLCFLDNQRGRE

Specific function: Arginine biosynthesis; sixth step. [C]

COG id: COG0078

COG function: function code E; Ornithine carbamoyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATCase/OTCase family [H]

Homologues:

Organism=Homo sapiens, GI38788445, Length=304, Percent_Identity=38.8157894736842, Blast_Score=222, Evalue=3e-58,
Organism=Homo sapiens, GI18105007, Length=309, Percent_Identity=26.8608414239482, Blast_Score=101, Evalue=1e-21,
Organism=Escherichia coli, GI1786469, Length=329, Percent_Identity=36.1702127659575, Blast_Score=197, Evalue=8e-52,
Organism=Escherichia coli, GI1790703, Length=329, Percent_Identity=35.5623100303951, Blast_Score=191, Evalue=7e-50,
Organism=Escherichia coli, GI48994908, Length=307, Percent_Identity=24.4299674267101, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI2367364, Length=316, Percent_Identity=27.8481012658228, Blast_Score=81, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI193204318, Length=325, Percent_Identity=22.4615384615385, Blast_Score=75, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6322373, Length=324, Percent_Identity=38.2716049382716, Blast_Score=223, Evalue=4e-59,
Organism=Saccharomyces cerevisiae, GI6322331, Length=306, Percent_Identity=25.8169934640523, Blast_Score=92, Evalue=9e-20,
Organism=Drosophila melanogaster, GI24642586, Length=315, Percent_Identity=26.6666666666667, Blast_Score=98, Evalue=9e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006132
- InterPro:   IPR006130
- InterPro:   IPR006131
- InterPro:   IPR002292 [H]

Pfam domain/function: PF00185 OTCace; PF02729 OTCace_N [H]

EC number: =2.1.3.3 [H]

Molecular weight: Translated: 34960; Mature: 34960

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: PS00097 CARBAMOYLTRANSFERASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHFLTLRDFSKEEILSLVNHASELKKEPKKLLQDKTLAMIFEKNSTRTRMAFELAITEL
CCCEEEHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHC
GGKALFLSSNDLQLSRGEPVKDTARVIGAMVDFVMMRVNKHETLLEFARYSKAPVINALS
CCCEEEEECCCCEECCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHH
ELYHPTQVLGDLLTIKEWNKMQNGIAKVAFIGDSNNMCNSWLIAAAILGFEFSIAIPKNY
HHCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHCEEEEECCCCC
KISPEIWEFAMKQALISGAKISLSHDRFEALKDKDVVITDTWVSMGEENEKERKIKEFEG
CCCHHHHHHHHHHHHHCCCEEEECHHHHHHHCCCCEEEEEHHHHCCCCCHHHHHHHHHCC
FMIDEKAMSVANKDAILLHCLPAYRGYEVSEEIFEKHADVIFEEARNRLYVVKALLCFLD
CEECHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NQRGRE
CCCCCC
>Mature Secondary Structure
MKHFLTLRDFSKEEILSLVNHASELKKEPKKLLQDKTLAMIFEKNSTRTRMAFELAITEL
CCCEEEHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHC
GGKALFLSSNDLQLSRGEPVKDTARVIGAMVDFVMMRVNKHETLLEFARYSKAPVINALS
CCCEEEEECCCCEECCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHH
ELYHPTQVLGDLLTIKEWNKMQNGIAKVAFIGDSNNMCNSWLIAAAILGFEFSIAIPKNY
HHCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHCEEEEECCCCC
KISPEIWEFAMKQALISGAKISLSHDRFEALKDKDVVITDTWVSMGEENEKERKIKEFEG
CCCHHHHHHHHHHHHHCCCEEEECHHHHHHHCCCCEEEEEHHHHCCCCCHHHHHHHHHCC
FMIDEKAMSVANKDAILLHCLPAYRGYEVSEEIFEKHADVIFEEARNRLYVVKALLCFLD
CEECHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NQRGRE
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA