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The map label for this gene is cysS [H]

Identifier: 57237647

GI number: 57237647

Start: 831712

End: 833100

Strand: Direct

Name: cysS [H]

Synonym: CJE0893

Alternate gene names: 57237647

Gene position: 831712-833100 (Clockwise)

Preceding gene: 57237646

Following gene: 57237648

Centisome position: 46.78

GC content: 28.94

Gene sequence:

>1389_bases
ATGAGATTATTAGATAGTGTAACAAAAGAGAAAATAAAACTTGATAAAAAAGATATTAGTATTTACTTATGCGGGCCTAC
GGTTTATGATGATGCACATTTAGGACATGCAAGAAGTAGTGTTTGTTTTGATCTTTTGCGTAGAGTTTTACTTGCTCAGG
GCAATAGGGTAAAATTTGCTAGAAATTATACAGATATTGATGATAAGATTTTGAAAAAAATGACACAAAGTGGTCAAACT
TTAGAGGAAATTACGGAATTTTATATCAAAAGTTATGAAGAGGATATGAGGGCTTTAAATGTATTAGATCCTGATTTTAA
ACCTCGTGCAACGCATTATATAACAGCTATGCTTGATTTGATTAAAAAGCTTGCTAAGGATGGGTTTGTTTATACTCTAG
AAGATGGAATTTACTTTGATACAAGTAAAGATGAAAAATATTTAAGCCTATCAAATCGCAATTTAGAAGAAAATATTTCT
CGTCTAAGTAATGAAGTGCAAAAAAGAAATGAAAGCGATTTTGTGCTTTGGAAATTTGATGAAAATTTTTACGAAAATGA
ATTTGGCAAAGGGCGTCCAGGTTGGCATACTGAATGTGTTGCTATGATTGATTCTATTTTTGAAAATACTCTTGATATAC
ATGCTGGAGGGATAGATTTGCTTTTTCCTCATCATGAAAATGAAGCTGCGCAATGTCGTTGTGGATGTAAGAGAAAATTA
GCAAATATTTGGCTTCACAATGGTTTTGTAAAAATCGATGGCGAAAAAATGAGTAAAAGTTTAAATAATAGTTTTTTTAT
AAAAGATGCTTTAAAAGAATTTATGGGCGAAGCTTTAAGATTTTATCTTTTGAGTTCTCATTATAGATCTCATTTTAATT
ATTCTTTATCGGATTTAGAAAATGCTAAAAAACGTTTAGATAAATTTTATCGCCTTAAAAAAAGATTGGATTTAGGTGAA
ATTTCTGATTTTGATGTTTTAAATGATATTGAAATAAAAAGCGAAATTGCTAAGCAAATTTTAGAGATTTTAAATGATGA
TTTAAATGTTTCTAAAGCCTTGGCTCTTTTGGATGATTTTATCAGTAGTGCAAATTTAGAGTTGGATAAAGAAAGCAAAA
ATAAAATTTTAAAACAAAATATCAAAGAAGCTTTAAGTGAGCTAGCTAAAATTTTTGGCTTTGGTTTTATGGATACAACT
TTATATTTTCAATGGGGTGTAAGCAAAGAAGAACGAGAAGAGATTGAAAAGTTAATTTTAGAAAGAACTGAGGCTAAGAA
AAACAAAGATTTTAACACAGCTGATGCAATAAGAGAGCAATTAAATAGTAAAAAAATCACTCTTTTAGATACTCCAAATG
GAACAATTTGGGAGAAAATAAATGCATAA

Upstream 100 bases:

>100_bases
TAGTTGCTTTGATTGTTTTTACGATCTTACTTATTTTGATTAAACCTTATATTTTAAGTTTTTTTATAGGAATTTTTACA
AGTTTTAAAGGAGTTTTTTA

Downstream 100 bases:

>100_bases
TGAGATGAATTTAAAAGAGGTTTTAATACGCTTTAAGCCCTTTTATAAAAGATATTGGAAGCAATTTGCTATAGCTATTT
TTGGTATGATTTTAGCAAGC

Product: cysteinyl-tRNA synthetase

Products: NA

Alternate protein names: Cysteine--tRNA ligase; CysRS [H]

Number of amino acids: Translated: 462; Mature: 462

Protein sequence:

>462_residues
MRLLDSVTKEKIKLDKKDISIYLCGPTVYDDAHLGHARSSVCFDLLRRVLLAQGNRVKFARNYTDIDDKILKKMTQSGQT
LEEITEFYIKSYEEDMRALNVLDPDFKPRATHYITAMLDLIKKLAKDGFVYTLEDGIYFDTSKDEKYLSLSNRNLEENIS
RLSNEVQKRNESDFVLWKFDENFYENEFGKGRPGWHTECVAMIDSIFENTLDIHAGGIDLLFPHHENEAAQCRCGCKRKL
ANIWLHNGFVKIDGEKMSKSLNNSFFIKDALKEFMGEALRFYLLSSHYRSHFNYSLSDLENAKKRLDKFYRLKKRLDLGE
ISDFDVLNDIEIKSEIAKQILEILNDDLNVSKALALLDDFISSANLELDKESKNKILKQNIKEALSELAKIFGFGFMDTT
LYFQWGVSKEEREEIEKLILERTEAKKNKDFNTADAIREQLNSKKITLLDTPNGTIWEKINA

Sequences:

>Translated_462_residues
MRLLDSVTKEKIKLDKKDISIYLCGPTVYDDAHLGHARSSVCFDLLRRVLLAQGNRVKFARNYTDIDDKILKKMTQSGQT
LEEITEFYIKSYEEDMRALNVLDPDFKPRATHYITAMLDLIKKLAKDGFVYTLEDGIYFDTSKDEKYLSLSNRNLEENIS
RLSNEVQKRNESDFVLWKFDENFYENEFGKGRPGWHTECVAMIDSIFENTLDIHAGGIDLLFPHHENEAAQCRCGCKRKL
ANIWLHNGFVKIDGEKMSKSLNNSFFIKDALKEFMGEALRFYLLSSHYRSHFNYSLSDLENAKKRLDKFYRLKKRLDLGE
ISDFDVLNDIEIKSEIAKQILEILNDDLNVSKALALLDDFISSANLELDKESKNKILKQNIKEALSELAKIFGFGFMDTT
LYFQWGVSKEEREEIEKLILERTEAKKNKDFNTADAIREQLNSKKITLLDTPNGTIWEKINA
>Mature_462_residues
MRLLDSVTKEKIKLDKKDISIYLCGPTVYDDAHLGHARSSVCFDLLRRVLLAQGNRVKFARNYTDIDDKILKKMTQSGQT
LEEITEFYIKSYEEDMRALNVLDPDFKPRATHYITAMLDLIKKLAKDGFVYTLEDGIYFDTSKDEKYLSLSNRNLEENIS
RLSNEVQKRNESDFVLWKFDENFYENEFGKGRPGWHTECVAMIDSIFENTLDIHAGGIDLLFPHHENEAAQCRCGCKRKL
ANIWLHNGFVKIDGEKMSKSLNNSFFIKDALKEFMGEALRFYLLSSHYRSHFNYSLSDLENAKKRLDKFYRLKKRLDLGE
ISDFDVLNDIEIKSEIAKQILEILNDDLNVSKALALLDDFISSANLELDKESKNKILKQNIKEALSELAKIFGFGFMDTT
LYFQWGVSKEEREEIEKLILERTEAKKNKDFNTADAIREQLNSKKITLLDTPNGTIWEKINA

Specific function: Unknown

COG id: COG0215

COG function: function code J; Cysteinyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI13375695, Length=314, Percent_Identity=40.1273885350318, Blast_Score=214, Evalue=2e-55,
Organism=Homo sapiens, GI303304987, Length=367, Percent_Identity=31.3351498637602, Blast_Score=166, Evalue=3e-41,
Organism=Homo sapiens, GI21269877, Length=367, Percent_Identity=31.3351498637602, Blast_Score=166, Evalue=3e-41,
Organism=Homo sapiens, GI62240992, Length=367, Percent_Identity=31.3351498637602, Blast_Score=166, Evalue=4e-41,
Organism=Homo sapiens, GI10835051, Length=367, Percent_Identity=31.3351498637602, Blast_Score=166, Evalue=5e-41,
Organism=Escherichia coli, GI1786737, Length=470, Percent_Identity=35.7446808510638, Blast_Score=297, Evalue=9e-82,
Organism=Caenorhabditis elegans, GI17509795, Length=357, Percent_Identity=32.7731092436975, Blast_Score=157, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI17509797, Length=357, Percent_Identity=32.7731092436975, Blast_Score=157, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6324082, Length=330, Percent_Identity=30.9090909090909, Blast_Score=158, Evalue=2e-39,
Organism=Drosophila melanogaster, GI19922218, Length=380, Percent_Identity=36.0526315789474, Blast_Score=223, Evalue=3e-58,
Organism=Drosophila melanogaster, GI19922364, Length=348, Percent_Identity=31.8965517241379, Blast_Score=167, Evalue=1e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015803
- InterPro:   IPR015273
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF09190 DALR_2; PF01406 tRNA-synt_1e [H]

EC number: =6.1.1.16 [H]

Molecular weight: Translated: 53645; Mature: 53645

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLLDSVTKEKIKLDKKDISIYLCGPTVYDDAHLGHARSSVCFDLLRRVLLAQGNRVKFA
CCHHHHHHHHHHHCCCCCEEEEEECCCEECCCCCCHHHHHHHHHHHHHHHHHCCCEEEEE
RNYTDIDDKILKKMTQSGQTLEEITEFYIKSYEEDMRALNVLDPDFKPRATHYITAMLDL
CCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
IKKLAKDGFVYTLEDGIYFDTSKDEKYLSLSNRNLEENISRLSNEVQKRNESDFVLWKFD
HHHHHHCCCEEEEECCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEC
ENFYENEFGKGRPGWHTECVAMIDSIFENTLDIHAGGIDLLFPHHENEAAQCRCGCKRKL
CCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHEECCCEEEECCCCCCCHHHHHHHHHHHH
ANIWLHNGFVKIDGEKMSKSLNNSFFIKDALKEFMGEALRFYLLSSHYRSHFNYSLSDLE
HHHHHCCCEEEECHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
NAKKRLDKFYRLKKRLDLGEISDFDVLNDIEIKSEIAKQILEILNDDLNVSKALALLDDF
HHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
ISSANLELDKESKNKILKQNIKEALSELAKIFGFGFMDTTLYFQWGVSKEEREEIEKLIL
HHHCCCEECCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHEEEEEECCCHHHHHHHHHHHH
ERTEAKKNKDFNTADAIREQLNSKKITLLDTPNGTIWEKINA
HHHHHHCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCCCC
>Mature Secondary Structure
MRLLDSVTKEKIKLDKKDISIYLCGPTVYDDAHLGHARSSVCFDLLRRVLLAQGNRVKFA
CCHHHHHHHHHHHCCCCCEEEEEECCCEECCCCCCHHHHHHHHHHHHHHHHHCCCEEEEE
RNYTDIDDKILKKMTQSGQTLEEITEFYIKSYEEDMRALNVLDPDFKPRATHYITAMLDL
CCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
IKKLAKDGFVYTLEDGIYFDTSKDEKYLSLSNRNLEENISRLSNEVQKRNESDFVLWKFD
HHHHHHCCCEEEEECCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEC
ENFYENEFGKGRPGWHTECVAMIDSIFENTLDIHAGGIDLLFPHHENEAAQCRCGCKRKL
CCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHEECCCEEEECCCCCCCHHHHHHHHHHHH
ANIWLHNGFVKIDGEKMSKSLNNSFFIKDALKEFMGEALRFYLLSSHYRSHFNYSLSDLE
HHHHHCCCEEEECHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
NAKKRLDKFYRLKKRLDLGEISDFDVLNDIEIKSEIAKQILEILNDDLNVSKALALLDDF
HHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
ISSANLELDKESKNKILKQNIKEALSELAKIFGFGFMDTTLYFQWGVSKEEREEIEKLIL
HHHCCCEECCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHEEEEEECCCHHHHHHHHHHHH
ERTEAKKNKDFNTADAIREQLNSKKITLLDTPNGTIWEKINA
HHHHHHCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA