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The map label for this gene is atoS [H]

Identifier: 57237638

GI number: 57237638

Start: 821817

End: 822836

Strand: Direct

Name: atoS [H]

Synonym: CJE0884

Alternate gene names: 57237638

Gene position: 821817-822836 (Clockwise)

Preceding gene: 57237637

Following gene: 57237639

Centisome position: 46.23

GC content: 30.88

Gene sequence:

>1020_bases
ATGAATGAAAGTATTTTAAAAAGTTTAGACTCAAATGAAAAAGAAACCCTACAAAAAGGCTTAGAAAGTCTTATAGAACA
AACTTATGTAATAGAAAATGAATACAAAACTTTAAATGAAAACTATAACTCCTTACGCGCAATGGTTGATGAGATTATAG
AGGTGTTGCCTAGTGCGCTTTGGATTTTAGATAAAGAAAAAAATATTATTTTACAAAATCAAGAAGCCTTGAAAAATCCA
AAATTACTTAGTATCATTAGTCTTGATAAAATTCGTGATGAGCTTGAATTTGAAGGTAGGTTTTATGCGGTAAAAATCAT
AGCGCATAATGAAAAAACTATAGTTTCAGCTACAGATATTAGCGATGAAAAACGCAATGAAAGGCTTGCAAGCATGGGTA
GTGTAGCGGCTCATTTGGCACATGAGATAAGAAATCCTATTGGATCTATATCTTTACTTGCTTCAACCCTTTTTGCTCGT
AGTGAGCTTAAAAATAAGCATATAGTTCTTGAAATCCAAAAGGCTATTGCTAGAGTGGAGCGTATCGTAAATTCAACTCT
ACTTTTTACTAAGGGTGTACACATCAATGCTTTAAATTTTAATCTTTTAGAGTTAAAAGAAGAGTGTGAAAGTGCCATTA
ACTCTTATAATTTCACTTCTCAAATAGACTTTGAAATATCTTTTTTGGATAAGCAGATTTGTGCTGATAAAGCTCTTCTT
GGTTTGGTTTTGCAAAATTTGATTTATAATGCTATTGATGCGATAGAAGAAAGCGAATGTGAAAAGCCTATGATTAAAAT
TTTAGCAAGTTATGATAATGAAAAAATATGCATCAGAGTGTATGATAATGGTTGTGAAATAAAAGATGAGAAATTGGTTT
TTGAAGCTTTTAAAACAACAAAACTTAAAGGCAATGGACTTGGCTTATCTCTTTCTAAAGAAATCATAAACGCTCATAAG
GGAGAGTTAAGTTTTCAAAGTGATCCTAAGAATTTTTATTTTACCTTACCTTTGGTGTGA

Upstream 100 bases:

>100_bases
CTCAAAAAATGGTTTTAGCAAGGAATTTGATAAAATATGCGAACAGAATTTGCTTTTACTTGATTTGAATGATTTTAAGA
TTTTATTAGAGGAATGATAA

Downstream 100 bases:

>100_bases
TAAATATTTTCTTTTCACCCCAAAACGGAACAGATTTTGCTTATATTATTTTAATATATTTAGATTGAAGGCAGAAAAAT
CTAAATCAAGGAATTAATAT

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MNESILKSLDSNEKETLQKGLESLIEQTYVIENEYKTLNENYNSLRAMVDEIIEVLPSALWILDKEKNIILQNQEALKNP
KLLSIISLDKIRDELEFEGRFYAVKIIAHNEKTIVSATDISDEKRNERLASMGSVAAHLAHEIRNPIGSISLLASTLFAR
SELKNKHIVLEIQKAIARVERIVNSTLLFTKGVHINALNFNLLELKEECESAINSYNFTSQIDFEISFLDKQICADKALL
GLVLQNLIYNAIDAIEESECEKPMIKILASYDNEKICIRVYDNGCEIKDEKLVFEAFKTTKLKGNGLGLSLSKEIINAHK
GELSFQSDPKNFYFTLPLV

Sequences:

>Translated_339_residues
MNESILKSLDSNEKETLQKGLESLIEQTYVIENEYKTLNENYNSLRAMVDEIIEVLPSALWILDKEKNIILQNQEALKNP
KLLSIISLDKIRDELEFEGRFYAVKIIAHNEKTIVSATDISDEKRNERLASMGSVAAHLAHEIRNPIGSISLLASTLFAR
SELKNKHIVLEIQKAIARVERIVNSTLLFTKGVHINALNFNLLELKEECESAINSYNFTSQIDFEISFLDKQICADKALL
GLVLQNLIYNAIDAIEESECEKPMIKILASYDNEKICIRVYDNGCEIKDEKLVFEAFKTTKLKGNGLGLSLSKEIINAHK
GELSFQSDPKNFYFTLPLV
>Mature_339_residues
MNESILKSLDSNEKETLQKGLESLIEQTYVIENEYKTLNENYNSLRAMVDEIIEVLPSALWILDKEKNIILQNQEALKNP
KLLSIISLDKIRDELEFEGRFYAVKIIAHNEKTIVSATDISDEKRNERLASMGSVAAHLAHEIRNPIGSISLLASTLFAR
SELKNKHIVLEIQKAIARVERIVNSTLLFTKGVHINALNFNLLELKEECESAINSYNFTSQIDFEISFLDKQICADKALL
GLVLQNLIYNAIDAIEESECEKPMIKILASYDNEKICIRVYDNGCEIKDEKLVFEAFKTTKLKGNGLGLSLSKEIINAHK
GELSFQSDPKNFYFTLPLV

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=222, Percent_Identity=33.3333333333333, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI1790436, Length=230, Percent_Identity=33.9130434782609, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1788279, Length=229, Percent_Identity=31.4410480349345, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 38444; Mature: 38444

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNESILKSLDSNEKETLQKGLESLIEQTYVIENEYKTLNENYNSLRAMVDEIIEVLPSAL
CCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
WILDKEKNIILQNQEALKNPKLLSIISLDKIRDELEFEGRFYAVKIIAHNEKTIVSATDI
EEEECCCCEEEECHHHHCCCCEEEEHHHHHHHHHHCCCCEEEEEEEEEECCCEEEEECCC
SDEKRNERLASMGSVAAHLAHEIRNPIGSISLLASTLFARSELKNKHIVLEIQKAIARVE
CHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHH
RIVNSTLLFTKGVHINALNFNLLELKEECESAINSYNFTSQIDFEISFLDKQICADKALL
HHHHHHHEEECCEEEEEECCHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHH
GLVLQNLIYNAIDAIEESECEKPMIKILASYDNEKICIRVYDNGCEIKDEKLVFEAFKTT
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHH
KLKGNGLGLSLSKEIINAHKGELSFQSDPKNFYFTLPLV
EECCCCCCCHHHHHHHHCCCCCCCCCCCCCCEEEEECCC
>Mature Secondary Structure
MNESILKSLDSNEKETLQKGLESLIEQTYVIENEYKTLNENYNSLRAMVDEIIEVLPSAL
CCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
WILDKEKNIILQNQEALKNPKLLSIISLDKIRDELEFEGRFYAVKIIAHNEKTIVSATDI
EEEECCCCEEEECHHHHCCCCEEEEHHHHHHHHHHCCCCEEEEEEEEEECCCEEEEECCC
SDEKRNERLASMGSVAAHLAHEIRNPIGSISLLASTLFARSELKNKHIVLEIQKAIARVE
CHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHH
RIVNSTLLFTKGVHINALNFNLLELKEECESAINSYNFTSQIDFEISFLDKQICADKALL
HHHHHHHEEECCEEEEEECCHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHH
GLVLQNLIYNAIDAIEESECEKPMIKILASYDNEKICIRVYDNGCEIKDEKLVFEAFKTT
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHH
KLKGNGLGLSLSKEIINAHKGELSFQSDPKNFYFTLPLV
EECCCCCCCHHHHHHHHCCCCCCCCCCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]