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The map label for this gene is ccmE

Identifier: 54296881

GI number: 54296881

Start: 1027565

End: 1027996

Strand: Direct

Name: ccmE

Synonym: lpp0922

Alternate gene names: 54296881

Gene position: 1027565-1027996 (Clockwise)

Preceding gene: 54296880

Following gene: 54296882

Centisome position: 29.33

GC content: 41.44

Gene sequence:

>432_bases
ATGACCCCTGTACGGCGACGCAAATTATTTATCTTACTGTTTGCCCTGTCTGTTTTATCTGCAGCGGCTGCCTTGGTTCT
ATATGCCTTAAGACAAAATATCAGTTTATTTTACACCCCCACGCAGATTGTTGCGGGAGAAGCACCAGCAAAACACCACA
TCCGAGTTGGAGGTATGGTGGAAGCAAACAGCATAGTGCGTGCCAAAAAAGGTTTGGATGTCCAGTTTAAAATTACAGAT
TTTGAAAACACGATTGTTGTTACCTATTCAGGGATACTTCCCGATTTATTTCGAGAAGGGCAAGGAATAGTTGCGGAAGG
AGAAGTAACTGATAATCATCATTTTCATGCTACACAAGTTTTGGCAAAACACGATGCCAATTATATGCCACCTCAAGTAA
AGTCTGCTTTAGCTGATAAGGTGAAACAATGA

Upstream 100 bases:

>100_bases
GTTTGGTTTGCGTGGTTTTGGGCATGAATATTTTAGGAATAAAGTGGCAAAGAACTCGTACCCGCAAAAAATTACAACGT
TGGTTTAAGAGATAGGTTAA

Downstream 100 bases:

>100_bases
TAGCGGAATTAGGGCTGTTTTTTTTGGTTTTGGCTTTAGTGGCTTCTTTGATGTTAGCTTTGATCCCATTGGCGGGTTTG
CAATTCAATCGGAAAGACTG

Product: cytochrome c-type biogenesis protein CcmE

Products: NA

Alternate protein names: Cytochrome c maturation protein E; Heme chaperone CcmE

Number of amino acids: Translated: 143; Mature: 142

Protein sequence:

>143_residues
MTPVRRRKLFILLFALSVLSAAAALVLYALRQNISLFYTPTQIVAGEAPAKHHIRVGGMVEANSIVRAKKGLDVQFKITD
FENTIVVTYSGILPDLFREGQGIVAEGEVTDNHHFHATQVLAKHDANYMPPQVKSALADKVKQ

Sequences:

>Translated_143_residues
MTPVRRRKLFILLFALSVLSAAAALVLYALRQNISLFYTPTQIVAGEAPAKHHIRVGGMVEANSIVRAKKGLDVQFKITD
FENTIVVTYSGILPDLFREGQGIVAEGEVTDNHHFHATQVLAKHDANYMPPQVKSALADKVKQ
>Mature_142_residues
TPVRRRKLFILLFALSVLSAAAALVLYALRQNISLFYTPTQIVAGEAPAKHHIRVGGMVEANSIVRAKKGLDVQFKITDF
ENTIVVTYSGILPDLFREGQGIVAEGEVTDNHHFHATQVLAKHDANYMPPQVKSALADKVKQ

Specific function: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH

COG id: COG2332

COG function: function code O; Cytochrome c-type biogenesis protein CcmE

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmE/CycJ family

Homologues:

Organism=Escherichia coli, GI1788525, Length=139, Percent_Identity=47.4820143884892, Blast_Score=133, Evalue=4e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CCME_LEGPA (Q5X6P3)

Other databases:

- EMBL:   CR628336
- RefSeq:   YP_123250.1
- ProteinModelPortal:   Q5X6P3
- SMR:   Q5X6P3
- STRING:   Q5X6P3
- GeneID:   3117313
- GenomeReviews:   CR628336_GR
- KEGG:   lpp:lpp0922
- LegioList:   lpp0922
- eggNOG:   COG2332
- HOGENOM:   HBG296631
- OMA:   HVEFAVH
- ProtClustDB:   PRK13254
- BioCyc:   LPNE297246:LPP0922-MONOMER
- HAMAP:   MF_01959
- InterPro:   IPR004329
- InterPro:   IPR012340
- Gene3D:   G3DSA:2.40.50.140

Pfam domain/function: PF03100 CcmE; SSF82093 Pyrv/PenolPyrv_Kinase_cat

EC number: NA

Molecular weight: Translated: 15766; Mature: 15634

Theoretical pI: Translated: 10.00; Mature: 10.00

Prosite motif: NA

Important sites: BINDING 124-124

Signals:

None

Transmembrane regions:

HASH(0x167545f8)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPVRRRKLFILLFALSVLSAAAALVLYALRQNISLFYTPTQIVAGEAPAKHHIRVGGMV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHEEECCCCCCCEEEECCEE
EANSIVRAKKGLDVQFKITDFENTIVVTYSGILPDLFREGQGIVAEGEVTDNHHFHATQV
ECCHHHHHHCCCCEEEEEECCCCEEEEEECCCCHHHHHCCCCEEEECCCCCCCCHHHHHH
LAKHDANYMPPQVKSALADKVKQ
HHHCCCCCCCHHHHHHHHHHHCH
>Mature Secondary Structure 
TPVRRRKLFILLFALSVLSAAAALVLYALRQNISLFYTPTQIVAGEAPAKHHIRVGGMV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHEEECCCCCCCEEEECCEE
EANSIVRAKKGLDVQFKITDFENTIVVTYSGILPDLFREGQGIVAEGEVTDNHHFHATQV
ECCHHHHHHCCCCEEEEEECCCCEEEEEECCCCHHHHHCCCCEEEECCCCCCCCHHHHHH
LAKHDANYMPPQVKSALADKVKQ
HHHCCCCCCCHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA