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The map label for this gene is obgE [H]

Identifier: 54295487

GI number: 54295487

Start: 2943659

End: 2944684

Strand: Reverse

Name: obgE [H]

Synonym: lpl2574

Alternate gene names: 54295487

Gene position: 2944684-2943659 (Counterclockwise)

Preceding gene: 54295488

Following gene: 54295485

Centisome position: 88.01

GC content: 43.18

Gene sequence:

>1026_bases
ATGAAATTCGTTGATGAAGCACTTATTAAAGTTGAAGCCGGAAAAGGAGGGAATGGTTGCTTAAGCTTCAGGAGAGAAAA
ATTTATTCCTCGTGGTGGCCCTGACGGGGGTGATGGGGGTGATGGAGGCAGTATTTATTTTGAGGCGAGCAGCGATTTAA
ATACCTTGATTGATTTTCGTTATACTCGTCAATACAAAGCAGAGAACGGACAATCAGGGATGGGTGGAAATTGTACCGGG
AAGAAAGGAGAGGATTTAACCATCAAAGTGCCAGTCGGTACTATGGTTTATGATGCCGATACAGGTGAATTGTTAGCTGA
TATCAGTCAACCAGGTGTTCCCATGCTGATTGCTCAGGGTGGGTTTCACGGTTTGGGTAACACTCGCTATAAAAGCAGCG
TGAATCGATCACCTAGACAAACAACACCCGGAAGCCCGGGTGAATCCAGAAATTTGCGTTTGGAGCTCCGAGTTTTGGCA
GACGTAGGTCTGTTAGGGCTTCCCAATGCAGGAAAGTCTACTTTAATAAGAGCCGTCTCCAGTTCAAAAGCAAAAGTGGC
TGACTACCCATTTACAACCTTACATCCAGGTTTAGGGGTGGTTCGCGTTTCACCCTATAAGAGTTTTGTCATGGCGGATA
TCCCAGGTCTTATAGAAGGCGCGGCTCAAGGAGCAGGATTGGGGCATCGGTTTTTAAAACATCTTTCACGTACCTGTGTC
TTGCTGCATGTTATTGATATTGCGCCTTTGGATGGGAGTGATCCTGTTGCTGATGCGAAAGCAATTCTTAATGAGTTGAC
TCAATATAATCCCGATCTGCTCAACAAACCCAGATGGTTGGTTTTAAATAAAATCGATATGTTACCTGATGCAAAGGAAA
GAGAAGAAAAAATTCAATCCATAATAAAAGGCTTGGAGTGGAAAGACAAAGTATTTTCTATTTCCGCTATAGAGAGTAAA
GGAACACAAGAACTTTGCTACGCTTTAATGCAATTGATTGATGAGATGAAAAAGTCTGAAGCTTAG

Upstream 100 bases:

>100_bases
TTCAATTCAGTCAATTAGCTTATCTGAACGCATTCATTGAAAATATTTTTTCCTTAAGCTTTGAATTTTGCGTAAGTCCT
ATTTTAGTCTAAGGTTAGGC

Downstream 100 bases:

>100_bases
CCATTCAGCGGCATAATGCACAACCATAGCACTTCGATAAGGAATCTGATGTGTTTCACGACCCTCTTGCATTTGATTGC
TGTAGTGAATGATTAATTTG

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg [H]

Number of amino acids: Translated: 341; Mature: 341

Protein sequence:

>341_residues
MKFVDEALIKVEAGKGGNGCLSFRREKFIPRGGPDGGDGGDGGSIYFEASSDLNTLIDFRYTRQYKAENGQSGMGGNCTG
KKGEDLTIKVPVGTMVYDADTGELLADISQPGVPMLIAQGGFHGLGNTRYKSSVNRSPRQTTPGSPGESRNLRLELRVLA
DVGLLGLPNAGKSTLIRAVSSSKAKVADYPFTTLHPGLGVVRVSPYKSFVMADIPGLIEGAAQGAGLGHRFLKHLSRTCV
LLHVIDIAPLDGSDPVADAKAILNELTQYNPDLLNKPRWLVLNKIDMLPDAKEREEKIQSIIKGLEWKDKVFSISAIESK
GTQELCYALMQLIDEMKKSEA

Sequences:

>Translated_341_residues
MKFVDEALIKVEAGKGGNGCLSFRREKFIPRGGPDGGDGGDGGSIYFEASSDLNTLIDFRYTRQYKAENGQSGMGGNCTG
KKGEDLTIKVPVGTMVYDADTGELLADISQPGVPMLIAQGGFHGLGNTRYKSSVNRSPRQTTPGSPGESRNLRLELRVLA
DVGLLGLPNAGKSTLIRAVSSSKAKVADYPFTTLHPGLGVVRVSPYKSFVMADIPGLIEGAAQGAGLGHRFLKHLSRTCV
LLHVIDIAPLDGSDPVADAKAILNELTQYNPDLLNKPRWLVLNKIDMLPDAKEREEKIQSIIKGLEWKDKVFSISAIESK
GTQELCYALMQLIDEMKKSEA
>Mature_341_residues
MKFVDEALIKVEAGKGGNGCLSFRREKFIPRGGPDGGDGGDGGSIYFEASSDLNTLIDFRYTRQYKAENGQSGMGGNCTG
KKGEDLTIKVPVGTMVYDADTGELLADISQPGVPMLIAQGGFHGLGNTRYKSSVNRSPRQTTPGSPGESRNLRLELRVLA
DVGLLGLPNAGKSTLIRAVSSSKAKVADYPFTTLHPGLGVVRVSPYKSFVMADIPGLIEGAAQGAGLGHRFLKHLSRTCV
LLHVIDIAPLDGSDPVADAKAILNELTQYNPDLLNKPRWLVLNKIDMLPDAKEREEKIQSIIKGLEWKDKVFSISAIESK
GTQELCYALMQLIDEMKKSEA

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI24308117, Length=338, Percent_Identity=38.1656804733728, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI111955139, Length=305, Percent_Identity=35.4098360655738, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI111955063, Length=208, Percent_Identity=36.5384615384615, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI58761500, Length=136, Percent_Identity=32.3529411764706, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI4758796, Length=118, Percent_Identity=38.135593220339, Blast_Score=69, Evalue=5e-12,
Organism=Escherichia coli, GI1789574, Length=335, Percent_Identity=63.5820895522388, Blast_Score=400, Evalue=1e-113,
Organism=Escherichia coli, GI1787454, Length=137, Percent_Identity=32.1167883211679, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1790615, Length=142, Percent_Identity=33.8028169014084, Blast_Score=68, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17508313, Length=337, Percent_Identity=38.8724035608309, Blast_Score=164, Evalue=4e-41,
Organism=Caenorhabditis elegans, GI17552324, Length=330, Percent_Identity=33.9393939393939, Blast_Score=149, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI17509631, Length=162, Percent_Identity=33.3333333333333, Blast_Score=79, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6321962, Length=221, Percent_Identity=34.841628959276, Blast_Score=113, Evalue=4e-26,
Organism=Saccharomyces cerevisiae, GI6319281, Length=127, Percent_Identity=36.2204724409449, Blast_Score=69, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6321773, Length=164, Percent_Identity=31.0975609756098, Blast_Score=66, Evalue=7e-12,
Organism=Drosophila melanogaster, GI20129375, Length=310, Percent_Identity=38.7096774193548, Blast_Score=172, Evalue=3e-43,
Organism=Drosophila melanogaster, GI24585318, Length=292, Percent_Identity=37.3287671232877, Blast_Score=167, Evalue=1e-41,
Organism=Drosophila melanogaster, GI24640873, Length=129, Percent_Identity=33.3333333333333, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24640877, Length=129, Percent_Identity=33.3333333333333, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24640875, Length=129, Percent_Identity=33.3333333333333, Blast_Score=69, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014100
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01018 GTP1_OBG; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 36750; Mature: 36750

Theoretical pI: Translated: 7.95; Mature: 7.95

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFVDEALIKVEAGKGGNGCLSFRREKFIPRGGPDGGDGGDGGSIYFEASSDLNTLIDFR
CCCHHCCCEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHH
YTRQYKAENGQSGMGGNCTGKKGEDLTIKVPVGTMVYDADTGELLADISQPGVPMLIAQG
HHHHHCCCCCCCCCCCCCCCCCCCCEEEEEECCEEEEECCCHHHHHHHCCCCCCEEEECC
GFHGLGNTRYKSSVNRSPRQTTPGSPGESRNLRLELRVLADVGLLGLPNAGKSTLIRAVS
CCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCEEEEEEEEECCCEEECCCCCHHHHHHHHH
SSKAKVADYPFTTLHPGLGVVRVSPYKSFVMADIPGLIEGAAQGAGLGHRFLKHLSRTCV
CCCCEECCCCCCEECCCCCEEEECCHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHEE
LLHVIDIAPLDGSDPVADAKAILNELTQYNPDLLNKPRWLVLNKIDMLPDAKEREEKIQS
EHHHEEECCCCCCCCHHHHHHHHHHHHHCCHHHHCCCCEEEEEHHHCCCCHHHHHHHHHH
IIKGLEWKDKVFSISAIESKGTQELCYALMQLIDEMKKSEA
HHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKFVDEALIKVEAGKGGNGCLSFRREKFIPRGGPDGGDGGDGGSIYFEASSDLNTLIDFR
CCCHHCCCEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHH
YTRQYKAENGQSGMGGNCTGKKGEDLTIKVPVGTMVYDADTGELLADISQPGVPMLIAQG
HHHHHCCCCCCCCCCCCCCCCCCCCEEEEEECCEEEEECCCHHHHHHHCCCCCCEEEECC
GFHGLGNTRYKSSVNRSPRQTTPGSPGESRNLRLELRVLADVGLLGLPNAGKSTLIRAVS
CCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCEEEEEEEEECCCEEECCCCCHHHHHHHHH
SSKAKVADYPFTTLHPGLGVVRVSPYKSFVMADIPGLIEGAAQGAGLGHRFLKHLSRTCV
CCCCEECCCCCCEECCCCCEEEECCHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHEE
LLHVIDIAPLDGSDPVADAKAILNELTQYNPDLLNKPRWLVLNKIDMLPDAKEREEKIQS
EHHHEEECCCCCCCCHHHHHHHHHHHHHCCHHHHCCCCEEEEEHHHCCCCHHHHHHHHHH
IIKGLEWKDKVFSISAIESKGTQELCYALMQLIDEMKKSEA
HHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA