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The map label for this gene is mraY [H]

Identifier: 54295454

GI number: 54295454

Start: 2898035

End: 2899120

Strand: Reverse

Name: mraY [H]

Synonym: lpl2540

Alternate gene names: 54295454

Gene position: 2899120-2898035 (Counterclockwise)

Preceding gene: 54295455

Following gene: 54295453

Centisome position: 86.65

GC content: 41.53

Gene sequence:

>1086_bases
ATGCTCTATTGGTTAACGCAGTTATTGCAGGGACAATATCATGCGTTTAGAGTTTTTCAATATTTGACATTCAGGTCTAT
TTTAGCCTCATTAACTGCCCTTATAGTGGGTTTGTTATGCGGCCCATTAATGATCCGCTGGTTAAGAGGGCTGCAAATAG
GCCAAATGGTTAGGAGTGATGGTCCCCAAACCCATTTATCAAAGGCGGGAACTCCCACTATGGGGGGCGTTTTGATTTTA
TTGGCCATCACTGTGAGTTGCTTGCTCTGGTGCGATTTAAGACAAACAAGCCTGTGGCTGGTGCTCTTGGTTACCTTGGC
TAATGGTTTGGTTGGTTGGGTTGATGATTATCGCAAGTTGGTATTAAAAAATAGCAAAGGATTACCTGGTCGTTGGAAAT
ATTTTTGGCAGTCAGTCATTGCTTTAGTTGCTGTCTCTTATTTGTATTGGAATGCCAGTTTGCCAGTACATACTCAGCTC
ACAGCTCCTTTTTTTAAAACGGTCACTTGGGATCTGGGCATTTTTTTTCCTGTACTTGCCTATTTCGTCATTGTTGGAAG
CAGTAATGCAGTGAATTTAACTGATGGGCTGGATGGCTTGGCTATTATGCCAATAGTAATGGTGGCTGGTGCCTTGGGTG
TGTTTGCCTATGCATCGAGTAACGCCGTATACTCTAATTATTTAGGAATCCCTTATGTGCCCAATACTGGTGAGCTAACG
ATTTTTTGTTCTTCTATTGTTGGTGCTGGCCTGGGTTTTCTTTGGTATAACAGTTATCCTGCTCAAGTTTTCATGGGCGA
TGTGGGCTCTTTGGCGTTAGGGGCAGCTTTAGGGATAGTTGCGGTTGTAGTTAGACAAGAACTTGTTTTGCTCATTATGG
GTGGATTATTTGTAATTGAGACGCTTTCTGTCATATTACAAGTAGGTTATTTTAAATATTCAGGCGGAAAAAGATTATTC
AGGATGGCCCCATTACATCACCATTTTGAATTAAAGGGGTGGTCAGAGCCCAAAGTGATAGTAAGATTTTGGATTATTAC
GGTTGTATTTGTGTTATGCGGATTGGCTACTTTAAAACTTCGATAG

Upstream 100 bases:

>100_bases
CGACAGGAATGTGGTATGCTTGGCCACTTTTTTGCCCCATTAAAGGAATTATGCTCAATAAAAATCATTGAGCATAATTT
TAAGAACAAGAGGAATAATT

Downstream 100 bases:

>100_bases
ACAAGGTGCATTCATGAATCATTCCTTATATTTGGTAGCAGGGCTGGGTAAGACGGGACTCTCTATAGCAAGATACCTGA
AGAGAAATAATAAATCGTTT

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase [H]

Number of amino acids: Translated: 361; Mature: 361

Protein sequence:

>361_residues
MLYWLTQLLQGQYHAFRVFQYLTFRSILASLTALIVGLLCGPLMIRWLRGLQIGQMVRSDGPQTHLSKAGTPTMGGVLIL
LAITVSCLLWCDLRQTSLWLVLLVTLANGLVGWVDDYRKLVLKNSKGLPGRWKYFWQSVIALVAVSYLYWNASLPVHTQL
TAPFFKTVTWDLGIFFPVLAYFVIVGSSNAVNLTDGLDGLAIMPIVMVAGALGVFAYASSNAVYSNYLGIPYVPNTGELT
IFCSSIVGAGLGFLWYNSYPAQVFMGDVGSLALGAALGIVAVVVRQELVLLIMGGLFVIETLSVILQVGYFKYSGGKRLF
RMAPLHHHFELKGWSEPKVIVRFWIITVVFVLCGLATLKLR

Sequences:

>Translated_361_residues
MLYWLTQLLQGQYHAFRVFQYLTFRSILASLTALIVGLLCGPLMIRWLRGLQIGQMVRSDGPQTHLSKAGTPTMGGVLIL
LAITVSCLLWCDLRQTSLWLVLLVTLANGLVGWVDDYRKLVLKNSKGLPGRWKYFWQSVIALVAVSYLYWNASLPVHTQL
TAPFFKTVTWDLGIFFPVLAYFVIVGSSNAVNLTDGLDGLAIMPIVMVAGALGVFAYASSNAVYSNYLGIPYVPNTGELT
IFCSSIVGAGLGFLWYNSYPAQVFMGDVGSLALGAALGIVAVVVRQELVLLIMGGLFVIETLSVILQVGYFKYSGGKRLF
RMAPLHHHFELKGWSEPKVIVRFWIITVVFVLCGLATLKLR
>Mature_361_residues
MLYWLTQLLQGQYHAFRVFQYLTFRSILASLTALIVGLLCGPLMIRWLRGLQIGQMVRSDGPQTHLSKAGTPTMGGVLIL
LAITVSCLLWCDLRQTSLWLVLLVTLANGLVGWVDDYRKLVLKNSKGLPGRWKYFWQSVIALVAVSYLYWNASLPVHTQL
TAPFFKTVTWDLGIFFPVLAYFVIVGSSNAVNLTDGLDGLAIMPIVMVAGALGVFAYASSNAVYSNYLGIPYVPNTGELT
IFCSSIVGAGLGFLWYNSYPAQVFMGDVGSLALGAALGIVAVVVRQELVLLIMGGLFVIETLSVILQVGYFKYSGGKRLF
RMAPLHHHFELKGWSEPKVIVRFWIITVVFVLCGLATLKLR

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan [H]

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786275, Length=361, Percent_Identity=61.4958448753463, Blast_Score=429, Evalue=1e-121,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4; PF10555 MraY_sig1 [H]

EC number: =2.7.8.13 [H]

Molecular weight: Translated: 39841; Mature: 39841

Theoretical pI: Translated: 9.70; Mature: 9.70

Prosite motif: PS01347 MRAY_1 ; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYWLTQLLQGQYHAFRVFQYLTFRSILASLTALIVGLLCGPLMIRWLRGLQIGQMVRSD
CHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCC
GPQTHLSKAGTPTMGGVLILLAITVSCLLWCDLRQTSLWLVLLVTLANGLVGWVDDYRKL
CCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHH
VLKNSKGLPGRWKYFWQSVIALVAVSYLYWNASLPVHTQLTAPFFKTVTWDLGIFFPVLA
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHHHHHHHHH
YFVIVGSSNAVNLTDGLDGLAIMPIVMVAGALGVFAYASSNAVYSNYLGIPYVPNTGELT
HHHHCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCCCCCCCEE
IFCSSIVGAGLGFLWYNSYPAQVFMGDVGSLALGAALGIVAVVVRQELVLLIMGGLFVIE
EEHHHHHHCCHHHHHCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLSVILQVGYFKYSGGKRLFRMAPLHHHFELKGWSEPKVIVRFWIITVVFVLCGLATLKL
HHHHHHHHHCEEECCCCCEEHCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHCHHHHCC
R
C
>Mature Secondary Structure
MLYWLTQLLQGQYHAFRVFQYLTFRSILASLTALIVGLLCGPLMIRWLRGLQIGQMVRSD
CHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCC
GPQTHLSKAGTPTMGGVLILLAITVSCLLWCDLRQTSLWLVLLVTLANGLVGWVDDYRKL
CCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHH
VLKNSKGLPGRWKYFWQSVIALVAVSYLYWNASLPVHTQLTAPFFKTVTWDLGIFFPVLA
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHHHHHHHHH
YFVIVGSSNAVNLTDGLDGLAIMPIVMVAGALGVFAYASSNAVYSNYLGIPYVPNTGELT
HHHHCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCCCCCCCEE
IFCSSIVGAGLGFLWYNSYPAQVFMGDVGSLALGAALGIVAVVVRQELVLLIMGGLFVIE
EEHHHHHHCCHHHHHCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLSVILQVGYFKYSGGKRLFRMAPLHHHFELKGWSEPKVIVRFWIITVVFVLCGLATLKL
HHHHHHHHHCEEECCCCCEEHCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHCHHHHCC
R
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA