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The map label for this gene is ftsW [H]

Identifier: 54295452

GI number: 54295452

Start: 2895497

End: 2896672

Strand: Reverse

Name: ftsW [H]

Synonym: lpl2538

Alternate gene names: 54295452

Gene position: 2896672-2895497 (Counterclockwise)

Preceding gene: 54295453

Following gene: 54295451

Centisome position: 86.58

GC content: 39.97

Gene sequence:

>1176_bases
ATGCGACCGAGACATTTAAATCAAAGAGGCAAACCCGTTAGCAGACCGATATCACTTTATGATAAATGGCTGATAGGGGC
AGTTTTTGGTTTGCTGATAATTGGTTTGATGATGGTGGCATCAAGCTCGGTTATGATTTCAACAAAGTACTTTCATCAAC
CTTTTCATTTTCTTATTCGCCAGGCTTGTTATTTATTTGTGGGACTCTTGCTGGCCTTAATTGTAGTGCGTACAGACAGC
AGTTTCTGGGAAAAAATAAGCATGCCCATGATGATTGGTTGCGTGTTTTTATTGCTCATTGTTTTAATCCCGGGTATTGG
TAAATCAGTGAATGGCAGTCGGCGTTGGTTAGCTTTAGGTCCGATTGGTGTGCAAGTCTCAGAATTAACCAAACTTGCAA
TGATATTCTATCTTTCCGGGTATTTGGTTCGCCAGCAAGAGGCGGTTTGTGAAAGCATTTTTGGATTCATTAAACCCATG
GCAATACTGGCTGTTGTTTCAGTTTTATTACTGCTCGAACCAGATTTTGGAGCGACAGTTGTCATTTCTGGCACAGTAAT
GGCTATGTTATTTTTAGCTGGAGTTAAATTAAGATACTATTTTGGTTTAATGCTGGTTGTAGTGACAGCACTTGCTCTGT
TAGCGGTATCTTCCCCCTATAGGGTTGCTCGCTTAACAGCCTTTTTGGATCCGTGGGCAGATCAATACAATAGTGGTTAT
CAATTGACTCAGTCATTGATTGCTTTTGGACGAGGTGGATGGTTTGGTACCGGATTAGGTGAAAGCATACAGAAATTACT
CTATCTACCTGAGGCACATACTGATTTTTTATTTGCTGTGATTGCTGAAGAATTAGGGTTATTTGGAATTTTAGTTGTCA
TCACATTGTATAGTATACTGGTTATTAGAGGATTAAACATAGGATATACCGCCTATACTCAAGAAAGGCATTTTGCATCC
TATACAGCCTATGGTTTGACTATTTGGTTAGCTTTACAGGCTTCTATTAATATGGGTGTTAATGCCGGACTTTTACCAAC
CAAAGGGCTAACTCTGCCTTTACTCAGTTATGGTGGGGCCAGTATGGTAATTAATTGTATCGTTATTGCACTATTATTGC
GCATAGATCATGAAAATCGTTGGCAGTCTCTTGGGTTGAGACCGCTAACGGCTTAA

Upstream 100 bases:

>100_bases
TCGTTTTATTATCTCCAGCTTGCGCCAGTTTGGATATGTTCCGTGATTTTAATCATAGGGGCGATGTGTTTACATCTTCA
GTGCGCGGATTGTGAACACG

Downstream 100 bases:

>100_bases
GGGGGAATATTGAATAACTCAGAGCAATTTTTATCTCCGCGCATGGGGCGTGTAGAGCAAATTCATTTTGTTGGTATTGG
TGGTGCCGGTATGTGTGGTA

Product: cell division protein ftsW

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MRPRHLNQRGKPVSRPISLYDKWLIGAVFGLLIIGLMMVASSSVMISTKYFHQPFHFLIRQACYLFVGLLLALIVVRTDS
SFWEKISMPMMIGCVFLLLIVLIPGIGKSVNGSRRWLALGPIGVQVSELTKLAMIFYLSGYLVRQQEAVCESIFGFIKPM
AILAVVSVLLLLEPDFGATVVISGTVMAMLFLAGVKLRYYFGLMLVVVTALALLAVSSPYRVARLTAFLDPWADQYNSGY
QLTQSLIAFGRGGWFGTGLGESIQKLLYLPEAHTDFLFAVIAEELGLFGILVVITLYSILVIRGLNIGYTAYTQERHFAS
YTAYGLTIWLALQASINMGVNAGLLPTKGLTLPLLSYGGASMVINCIVIALLLRIDHENRWQSLGLRPLTA

Sequences:

>Translated_391_residues
MRPRHLNQRGKPVSRPISLYDKWLIGAVFGLLIIGLMMVASSSVMISTKYFHQPFHFLIRQACYLFVGLLLALIVVRTDS
SFWEKISMPMMIGCVFLLLIVLIPGIGKSVNGSRRWLALGPIGVQVSELTKLAMIFYLSGYLVRQQEAVCESIFGFIKPM
AILAVVSVLLLLEPDFGATVVISGTVMAMLFLAGVKLRYYFGLMLVVVTALALLAVSSPYRVARLTAFLDPWADQYNSGY
QLTQSLIAFGRGGWFGTGLGESIQKLLYLPEAHTDFLFAVIAEELGLFGILVVITLYSILVIRGLNIGYTAYTQERHFAS
YTAYGLTIWLALQASINMGVNAGLLPTKGLTLPLLSYGGASMVINCIVIALLLRIDHENRWQSLGLRPLTA
>Mature_391_residues
MRPRHLNQRGKPVSRPISLYDKWLIGAVFGLLIIGLMMVASSSVMISTKYFHQPFHFLIRQACYLFVGLLLALIVVRTDS
SFWEKISMPMMIGCVFLLLIVLIPGIGKSVNGSRRWLALGPIGVQVSELTKLAMIFYLSGYLVRQQEAVCESIFGFIKPM
AILAVVSVLLLLEPDFGATVVISGTVMAMLFLAGVKLRYYFGLMLVVVTALALLAVSSPYRVARLTAFLDPWADQYNSGY
QLTQSLIAFGRGGWFGTGLGESIQKLLYLPEAHTDFLFAVIAEELGLFGILVVITLYSILVIRGLNIGYTAYTQERHFAS
YTAYGLTIWLALQASINMGVNAGLLPTKGLTLPLLSYGGASMVINCIVIALLLRIDHENRWQSLGLRPLTA

Specific function: This is a septum-peptidoglycan biosynthetic protein, involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=362, Percent_Identity=46.4088397790055, Blast_Score=329, Evalue=2e-91,
Organism=Escherichia coli, GI1786853, Length=333, Percent_Identity=32.1321321321321, Blast_Score=127, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR013437 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 43085; Mature: 43085

Theoretical pI: Translated: 9.67; Mature: 9.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPRHLNQRGKPVSRPISLYDKWLIGAVFGLLIIGLMMVASSSVMISTKYFHQPFHFLIR
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHH
QACYLFVGLLLALIVVRTDSSFWEKISMPMMIGCVFLLLIVLIPGIGKSVNGSRRWLALG
HHHHHHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEC
PIGVQVSELTKLAMIFYLSGYLVRQQEAVCESIFGFIKPMAILAVVSVLLLLEPDFGATV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEE
VISGTVMAMLFLAGVKLRYYFGLMLVVVTALALLAVSSPYRVARLTAFLDPWADQYNSGY
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCH
QLTQSLIAFGRGGWFGTGLGESIQKLLYLPEAHTDFLFAVIAEELGLFGILVVITLYSIL
HHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VIRGLNIGYTAYTQERHFASYTAYGLTIWLALQASINMGVNAGLLPTKGLTLPLLSYGGA
HHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCH
SMVINCIVIALLLRIDHENRWQSLGLRPLTA
HHHHHHHHHHHHHHCCCCCHHHHCCCCCCCC
>Mature Secondary Structure
MRPRHLNQRGKPVSRPISLYDKWLIGAVFGLLIIGLMMVASSSVMISTKYFHQPFHFLIR
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHH
QACYLFVGLLLALIVVRTDSSFWEKISMPMMIGCVFLLLIVLIPGIGKSVNGSRRWLALG
HHHHHHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEC
PIGVQVSELTKLAMIFYLSGYLVRQQEAVCESIFGFIKPMAILAVVSVLLLLEPDFGATV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEE
VISGTVMAMLFLAGVKLRYYFGLMLVVVTALALLAVSSPYRVARLTAFLDPWADQYNSGY
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCH
QLTQSLIAFGRGGWFGTGLGESIQKLLYLPEAHTDFLFAVIAEELGLFGILVVITLYSIL
HHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VIRGLNIGYTAYTQERHFASYTAYGLTIWLALQASINMGVNAGLLPTKGLTLPLLSYGGA
HHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCH
SMVINCIVIALLLRIDHENRWQSLGLRPLTA
HHHHHHHHHHHHHHCCCCCHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]