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The map label for this gene is ftsA [H]

Identifier: 54295447

GI number: 54295447

Start: 2890092

End: 2891330

Strand: Reverse

Name: ftsA [H]

Synonym: lpl2533

Alternate gene names: 54295447

Gene position: 2891330-2890092 (Counterclockwise)

Preceding gene: 54295448

Following gene: 54295446

Centisome position: 86.42

GC content: 42.7

Gene sequence:

>1239_bases
ATGGCTAAAAAAATAGAAAAAAATATTATCACAGGGTTGGATATTGGAACTTCAAAAATTATTGCATTAATTGGTGAAGT
AACATCAGATGGAACGATAGAAATTATAGGTATTGGCCGTCATCCCTCTCGCGGATTAAAGCGAGGAGTTGTAGTTGATA
TAGAAACCACAGTCAATTCAATCCAACGTGCTGTACAAGAAGCTGAATTAATGGCTGGCTGTGAGGTGAGGACTGTTTAC
GCAGGCATTGCTGGCAGCCATATACGTAGCCTCAATTCCCATGGTATTGTGGCCATCCGTGATCAGGAAGTATCTCAAGC
CGATGTGGAAAGAGTTATCGATGCAGCAAAGGCCGTGGCAATCCCTGCTGATCAAAAAATACTTCATATATTACCGCAAG
AATTTATCATTGATCATCAAGGCAGTATTCGTGAACCGATAGGCATGGCTGGTGTAAGGCTGGAATCTCGGGTTCATATT
GTTACTGGTTCTGTCAGTGCTGCCCAAAATATTGTGAAGTGTGTCAGGCGCTGTGGTTTGGATGTGATTGATATTATTCT
GGAGCAATTAGCTTCAAGCCATGCTGTTCTTACTGAGGATGAAAAAGAGCTTGGGGTTTGTTTAATTGACATAGGTGGCG
GCACTACTGACATTGCGATATTTTGTGAGGGAGCTATCCAGCATACCTCAGTCATACCGATTGCAGGCGATCAAGTGACA
AATGATATTGCAATGGCCTTGCGTACGCCAACCAAGGCGGCAGAAGCAATTAAGGTCAATCATGCTTGTGCATTACCAGA
ATTAGCCAATCCAAACCAAATGTTAGAAGTTACCAGTGTCAATGATAGGCCTGGGCGAAAAATCTCGGCCAAAGCTTTGG
CAGATGTCGTTTCAGCTCGATACGAGGAACTATTTTCATTGGTACGTAATGAATTACGCCGAAGCGGGTTTGAAGACCGT
TTGGCTGCTGGTATTGTTCTAACAGGTGGGGCTTCCAATGTAAGAGGAGCAATTGAGTTGGCCGAACTTTGTTTTGAAAT
GCCAGTCAGAAAAGGATGTGCGCATTATGTCTCTGGTTTGACAGAAGCGACAGAAAATCCTTCGTTTGCAACAGGGGTTG
GTTTACTGCTTCATGGCTTTCAACAGCAATATGAAAGTGGCTATAATGTGCCAGCAATGAATGATAATGGTAAAAGTATT
TGGTCACGCATGAAAGAATGGTTTCAAGGAAATTTTTAA

Upstream 100 bases:

>100_bases
ACCCTGCTGTTTTTGCTGAAAAAGCAGATCAGTTGGCTGGCGTGGACCTGCGTTATCCACGTGGCATGGCAGTGCAGTGG
AAACAACAAATGGGACGATA

Downstream 100 bases:

>100_bases
CTTTTCATGTAAAAACACTGATATGATGCTTAAAAATGTTCCTGGTATGGATAGAAATTGAGATATGGGGTTGCATGATA
TTTTGCATGACAACAAATGC

Product: ATP-binding cell division protein FtsA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 412; Mature: 411

Protein sequence:

>412_residues
MAKKIEKNIITGLDIGTSKIIALIGEVTSDGTIEIIGIGRHPSRGLKRGVVVDIETTVNSIQRAVQEAELMAGCEVRTVY
AGIAGSHIRSLNSHGIVAIRDQEVSQADVERVIDAAKAVAIPADQKILHILPQEFIIDHQGSIREPIGMAGVRLESRVHI
VTGSVSAAQNIVKCVRRCGLDVIDIILEQLASSHAVLTEDEKELGVCLIDIGGGTTDIAIFCEGAIQHTSVIPIAGDQVT
NDIAMALRTPTKAAEAIKVNHACALPELANPNQMLEVTSVNDRPGRKISAKALADVVSARYEELFSLVRNELRRSGFEDR
LAAGIVLTGGASNVRGAIELAELCFEMPVRKGCAHYVSGLTEATENPSFATGVGLLLHGFQQQYESGYNVPAMNDNGKSI
WSRMKEWFQGNF

Sequences:

>Translated_412_residues
MAKKIEKNIITGLDIGTSKIIALIGEVTSDGTIEIIGIGRHPSRGLKRGVVVDIETTVNSIQRAVQEAELMAGCEVRTVY
AGIAGSHIRSLNSHGIVAIRDQEVSQADVERVIDAAKAVAIPADQKILHILPQEFIIDHQGSIREPIGMAGVRLESRVHI
VTGSVSAAQNIVKCVRRCGLDVIDIILEQLASSHAVLTEDEKELGVCLIDIGGGTTDIAIFCEGAIQHTSVIPIAGDQVT
NDIAMALRTPTKAAEAIKVNHACALPELANPNQMLEVTSVNDRPGRKISAKALADVVSARYEELFSLVRNELRRSGFEDR
LAAGIVLTGGASNVRGAIELAELCFEMPVRKGCAHYVSGLTEATENPSFATGVGLLLHGFQQQYESGYNVPAMNDNGKSI
WSRMKEWFQGNF
>Mature_411_residues
AKKIEKNIITGLDIGTSKIIALIGEVTSDGTIEIIGIGRHPSRGLKRGVVVDIETTVNSIQRAVQEAELMAGCEVRTVYA
GIAGSHIRSLNSHGIVAIRDQEVSQADVERVIDAAKAVAIPADQKILHILPQEFIIDHQGSIREPIGMAGVRLESRVHIV
TGSVSAAQNIVKCVRRCGLDVIDIILEQLASSHAVLTEDEKELGVCLIDIGGGTTDIAIFCEGAIQHTSVIPIAGDQVTN
DIAMALRTPTKAAEAIKVNHACALPELANPNQMLEVTSVNDRPGRKISAKALADVVSARYEELFSLVRNELRRSGFEDRL
AAGIVLTGGASNVRGAIELAELCFEMPVRKGCAHYVSGLTEATENPSFATGVGLLLHGFQQQYESGYNVPAMNDNGKSIW
SRMKEWFQGNF

Specific function: This protein may be involved in anomalous filament growth. May be a component of the septum [H]

COG id: COG0849

COG function: function code D; Actin-like ATPase involved in cell division

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Escherichia coli, GI1786282, Length=420, Percent_Identity=44.7619047619048, Blast_Score=376, Evalue=1e-105,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020823
- InterPro:   IPR003494 [H]

Pfam domain/function: PF02491 FtsA [H]

EC number: NA

Molecular weight: Translated: 44227; Mature: 44096

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKKIEKNIITGLDIGTSKIIALIGEVTSDGTIEIIGIGRHPSRGLKRGVVVDIETTVNS
CCCHHHHHHHCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCEEEEEHHHHHH
IQRAVQEAELMAGCEVRTVYAGIAGSHIRSLNSHGIVAIRDQEVSQADVERVIDAAKAVA
HHHHHHHHHHHCCCCEEEHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHEE
IPADQKILHILPQEFIIDHQGSIREPIGMAGVRLESRVHIVTGSVSAAQNIVKCVRRCGL
CCCCCHHHHHCCHHHHCCCCCCCCCCCCCCCEEECCEEEEEECCHHHHHHHHHHHHHCCC
DVIDIILEQLASSHAVLTEDEKELGVCLIDIGGGTTDIAIFCEGAIQHTSVIPIAGDQVT
HHHHHHHHHHHCCCCEEECCCCCCCEEEEEECCCCEEEEEEECCCCCCCEEEEECCCHHH
NDIAMALRTPTKAAEAIKVNHACALPELANPNQMLEVTSVNDRPGRKISAKALADVVSAR
HHHHHHHCCCCHHHHHHEECCCCCCCCCCCCCCEEEEEECCCCCCCEEHHHHHHHHHHHH
YEELFSLVRNELRRSGFEDRLAAGIVLTGGASNVRGAIELAELCFEMPVRKGCAHYVSGL
HHHHHHHHHHHHHHCCCHHHHHCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TEATENPSFATGVGLLLHGFQQQYESGYNVPAMNDNGKSIWSRMKEWFQGNF
HHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AKKIEKNIITGLDIGTSKIIALIGEVTSDGTIEIIGIGRHPSRGLKRGVVVDIETTVNS
CCHHHHHHHCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCEEEEEHHHHHH
IQRAVQEAELMAGCEVRTVYAGIAGSHIRSLNSHGIVAIRDQEVSQADVERVIDAAKAVA
HHHHHHHHHHHCCCCEEEHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHEE
IPADQKILHILPQEFIIDHQGSIREPIGMAGVRLESRVHIVTGSVSAAQNIVKCVRRCGL
CCCCCHHHHHCCHHHHCCCCCCCCCCCCCCCEEECCEEEEEECCHHHHHHHHHHHHHCCC
DVIDIILEQLASSHAVLTEDEKELGVCLIDIGGGTTDIAIFCEGAIQHTSVIPIAGDQVT
HHHHHHHHHHHCCCCEEECCCCCCCEEEEEECCCCEEEEEEECCCCCCCEEEEECCCHHH
NDIAMALRTPTKAAEAIKVNHACALPELANPNQMLEVTSVNDRPGRKISAKALADVVSAR
HHHHHHHCCCCHHHHHHEECCCCCCCCCCCCCCEEEEEECCCCCCCEEHHHHHHHHHHHH
YEELFSLVRNELRRSGFEDRLAAGIVLTGGASNVRGAIELAELCFEMPVRKGCAHYVSGL
HHHHHHHHHHHHHHCCCHHHHHCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TEATENPSFATGVGLLLHGFQQQYESGYNVPAMNDNGKSIWSRMKEWFQGNF
HHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043; 8581173 [H]