| Definition | Legionella pneumophila str. Lens, complete genome. |
|---|---|
| Accession | NC_006369 |
| Length | 3,345,687 |
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The map label for this gene is hypF [H]
Identifier: 54295309
GI number: 54295309
Start: 2724100
End: 2726325
Strand: Reverse
Name: hypF [H]
Synonym: lpl2394
Alternate gene names: 54295309
Gene position: 2726325-2724100 (Counterclockwise)
Preceding gene: 54295310
Following gene: 54295308
Centisome position: 81.49
GC content: 42.27
Gene sequence:
>2226_bases ATGGAATTGGAACGGGTACAAATTAGCATTCAAGGACTAGTGCAAGGGGTTGGTTTTAGACCGTGTGTTTATAAGCTTGC CAAACAAATGGAATTAACTGGCTTTGTACAAAATAATGCATCAGGTGTTTTGATAGAAATTCAAGGCAACTATTTATCAC AATTTATTCCGAAATTAAGAGAGCAATTACCGCCTCTCGCAGCAATTCATAACCTAGAGTTCACTTCACTGCCAATTGTT CCGAACGAAAGAGCTTTTGAAATTCTTGATAGCCAGCAGGGTAAAATAAATACTGTCATTACTCCGGATGTTTGCATTTG TTCTGAATGCCTCGGCGAATTATTTGACCCTCAAAGCAGATACTATCGTTATCCTTTCTTAAATTGTACTCACTGTGGTC CAAGGTTCACAATTACCAGAAATCTGCCATATGATCGTTGTCAAACATCAATGAGCCAGTTTCCTCTTTGTCAATCGTGT CAATCGGATTATTTAAATCCTGATAACCGTCGCTATCACGCGCAACCTACAGCCTGTAGTCAATGTGGCCCGCAACTCGC ACTATCAGTCGACAAGGTGGCTCAAAGAATTCAGGAGGGGGAAATTATTGCTTTAAAAGGTTTGGGAGGGTATCAATTAA TCTGTGATGCTCGAAATGAAGAGACTATTTCAAAATTGCGGCTAAGAAAAAATCGTGAGGCCAAACCATTCGCTTTGATG GTAGCCAATGTAAAAAGTGCCGAAGAAATTGCCGAGGTAAGCTGCCAGGCCAGATTGGTATTGGAAAGCAGAGAAAGGCC GATTGTCTTGTTAAGAAAAAAGAAAGCACCTTTACCGGATGGGATTGCTCCTGGCTTAAATCATTTCGGTATCATGCTGC CTTCTACTCCATTACATTATTTGCTTTTTAATTCGTTCCTTGGCAACCCGGATTATTGCCAATGGCTGGATGAGTATCAT TTCATGGTATTAGTGGTGACCAGTGCGAACATAGGCGGTGAACCGCTCATTATTGATGATAAAAAGGCTGAGCAAGGTTT AAATTCTATAGCCGATAAAATTATCTCTCATGATCGGGAAATCATTACTCGCACAGATGACTCTGTTGTTCGCATGATTA ATGACACTTCAGTATTGATTCGTCGAGCACGCGGCTATGTGCCTGCTCCTTTAAGATTGCCTTATGAAATTCCCCCTACC GTGGCCTTGGGAGGACATCTTAAAAATACCTTCTGTATTACTCGTGGCGAAGAAGCTTTCGTTTCACAACATATTGGCAG TTTAAACAATAAAGCGACGATTGAGTATTTTCATGAGTCATTGAATCATTTATTAAAATTTCTTGCGGTCAAACCAGAAC GAATCGCTCATGATTGGCATCCTGATTTTTATACCAGTAGATTAGCGCAAAAGTATGATATACCTGTTTACGGGGTGCAG CATCATCATGCCCACTTGGCTTCTGTTGCAGCAGAACATGGAATTCAGGAGCCTGTATTAGGATTGGTTCTGGATGGCTA TGGGTTTGGTTCTGATGGCGAAGCTTGGGGGGGCGAATTATTATTACTGGAGAAGGCGGAATTTAAGCGCGTTGGACATT TTTTCCCTATTCCTCAGCCCGGAGGCGAACTTGCTGCAAGAGAACCCTGGCGTATGGCTGCTGGCATTTTGCATACGTTG GGAAGGGGGGATGAGATTTCGCAACGGTTTAAAGAGCAGCCCCAATCGCCATTTTTACTGCAATTATTGGAAAAAAAGAT TCATTGTCCGCTGACTACCAGTTGTGGGCGACTGTTTGATGCGGTCAGCGCACTTTTAGGTGTTGAATCGCTCTCCTTGT TTGAAGGTCATGCGGCCATGAGATTGGAAAGCATGGTGACTCATCCACAAGTCTTAAACAAAGGTTGGACGATAAACGGC AATGTTTTTGACATGCGGCCTACTTTACAGTTTATAGCAAACACGACAGATCAACAATTAGGGGCCAACCTGTTCCATGG TACTTTAATAGCAGGTCTTAGCGAGTGGGTTACAGGAGTTTGTCGAGAAAAAGGGATTCACATGTTACTATTGAGTGGCG GCTGTTTTTTAAACCGGGTTCTTGCGGAAGGCTTAATTAATTCATTAATTAAATCAGGTATTAAACCCCTGTTGCCCAAA TTGCTTCCACCAAATGATGGTGGAATTGCGCTAGGTCAAGCATGGATTGTTGGAATAAAAGAATAA
Upstream 100 bases:
>100_bases GTCAGCGGTTAATGGTGTTGGATTGAAGGATTGGTACGATTGGTTGTTGCATTCTTTTAGGTTGAATGTCCAGGCTTCTT CATAGAAAAAGTGGTAGCCC
Downstream 100 bases:
>100_bases GGGTGGCTTATGTGCTTAGCGTTGCCAGCGCAAATTGATCAGGTTTTGGAAGATAACAAGGCAATCGTTAATTTGGGTGG GATCACCAAGGAAATTTCCA
Product: hydrogenase maturation protein HypF
Products: NA
Alternate protein names: Carbamoyl phosphate-converting enzyme hypF2; [NiFe]-hydrogenase maturation factor hypF2; Hydrogenase maturation protein hypF2 [H]
Number of amino acids: Translated: 741; Mature: 741
Protein sequence:
>741_residues MELERVQISIQGLVQGVGFRPCVYKLAKQMELTGFVQNNASGVLIEIQGNYLSQFIPKLREQLPPLAAIHNLEFTSLPIV PNERAFEILDSQQGKINTVITPDVCICSECLGELFDPQSRYYRYPFLNCTHCGPRFTITRNLPYDRCQTSMSQFPLCQSC QSDYLNPDNRRYHAQPTACSQCGPQLALSVDKVAQRIQEGEIIALKGLGGYQLICDARNEETISKLRLRKNREAKPFALM VANVKSAEEIAEVSCQARLVLESRERPIVLLRKKKAPLPDGIAPGLNHFGIMLPSTPLHYLLFNSFLGNPDYCQWLDEYH FMVLVVTSANIGGEPLIIDDKKAEQGLNSIADKIISHDREIITRTDDSVVRMINDTSVLIRRARGYVPAPLRLPYEIPPT VALGGHLKNTFCITRGEEAFVSQHIGSLNNKATIEYFHESLNHLLKFLAVKPERIAHDWHPDFYTSRLAQKYDIPVYGVQ HHHAHLASVAAEHGIQEPVLGLVLDGYGFGSDGEAWGGELLLLEKAEFKRVGHFFPIPQPGGELAAREPWRMAAGILHTL GRGDEISQRFKEQPQSPFLLQLLEKKIHCPLTTSCGRLFDAVSALLGVESLSLFEGHAAMRLESMVTHPQVLNKGWTING NVFDMRPTLQFIANTTDQQLGANLFHGTLIAGLSEWVTGVCREKGIHMLLLSGGCFLNRVLAEGLINSLIKSGIKPLLPK LLPPNDGGIALGQAWIVGIKE
Sequences:
>Translated_741_residues MELERVQISIQGLVQGVGFRPCVYKLAKQMELTGFVQNNASGVLIEIQGNYLSQFIPKLREQLPPLAAIHNLEFTSLPIV PNERAFEILDSQQGKINTVITPDVCICSECLGELFDPQSRYYRYPFLNCTHCGPRFTITRNLPYDRCQTSMSQFPLCQSC QSDYLNPDNRRYHAQPTACSQCGPQLALSVDKVAQRIQEGEIIALKGLGGYQLICDARNEETISKLRLRKNREAKPFALM VANVKSAEEIAEVSCQARLVLESRERPIVLLRKKKAPLPDGIAPGLNHFGIMLPSTPLHYLLFNSFLGNPDYCQWLDEYH FMVLVVTSANIGGEPLIIDDKKAEQGLNSIADKIISHDREIITRTDDSVVRMINDTSVLIRRARGYVPAPLRLPYEIPPT VALGGHLKNTFCITRGEEAFVSQHIGSLNNKATIEYFHESLNHLLKFLAVKPERIAHDWHPDFYTSRLAQKYDIPVYGVQ HHHAHLASVAAEHGIQEPVLGLVLDGYGFGSDGEAWGGELLLLEKAEFKRVGHFFPIPQPGGELAAREPWRMAAGILHTL GRGDEISQRFKEQPQSPFLLQLLEKKIHCPLTTSCGRLFDAVSALLGVESLSLFEGHAAMRLESMVTHPQVLNKGWTING NVFDMRPTLQFIANTTDQQLGANLFHGTLIAGLSEWVTGVCREKGIHMLLLSGGCFLNRVLAEGLINSLIKSGIKPLLPK LLPPNDGGIALGQAWIVGIKE >Mature_741_residues MELERVQISIQGLVQGVGFRPCVYKLAKQMELTGFVQNNASGVLIEIQGNYLSQFIPKLREQLPPLAAIHNLEFTSLPIV PNERAFEILDSQQGKINTVITPDVCICSECLGELFDPQSRYYRYPFLNCTHCGPRFTITRNLPYDRCQTSMSQFPLCQSC QSDYLNPDNRRYHAQPTACSQCGPQLALSVDKVAQRIQEGEIIALKGLGGYQLICDARNEETISKLRLRKNREAKPFALM VANVKSAEEIAEVSCQARLVLESRERPIVLLRKKKAPLPDGIAPGLNHFGIMLPSTPLHYLLFNSFLGNPDYCQWLDEYH FMVLVVTSANIGGEPLIIDDKKAEQGLNSIADKIISHDREIITRTDDSVVRMINDTSVLIRRARGYVPAPLRLPYEIPPT VALGGHLKNTFCITRGEEAFVSQHIGSLNNKATIEYFHESLNHLLKFLAVKPERIAHDWHPDFYTSRLAQKYDIPVYGVQ HHHAHLASVAAEHGIQEPVLGLVLDGYGFGSDGEAWGGELLLLEKAEFKRVGHFFPIPQPGGELAAREPWRMAAGILHTL GRGDEISQRFKEQPQSPFLLQLLEKKIHCPLTTSCGRLFDAVSALLGVESLSLFEGHAAMRLESMVTHPQVLNKGWTING NVFDMRPTLQFIANTTDQQLGANLFHGTLIAGLSEWVTGVCREKGIHMLLLSGGCFLNRVLAEGLINSLIKSGIKPLLPK LLPPNDGGIALGQAWIVGIKE
Specific function: Along with hypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carb
COG id: COG0068
COG function: function code O; Hydrogenase maturation factor
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 YrdC-like domain [H]
Homologues:
Organism=Escherichia coli, GI2367152, Length=772, Percent_Identity=38.7305699481865, Blast_Score=456, Evalue=1e-129,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR001792 - InterPro: IPR017968 - InterPro: IPR004421 - InterPro: IPR017945 - InterPro: IPR006070 - InterPro: IPR011125 [H]
Pfam domain/function: PF00708 Acylphosphatase; PF01300 Sua5_yciO_yrdC; PF07503 zf-HYPF [H]
EC number: NA
Molecular weight: Translated: 82473; Mature: 82473
Theoretical pI: Translated: 7.13; Mature: 7.13
Prosite motif: PS00150 ACYLPHOSPHATASE_1 ; PS51160 ACYLPHOSPHATASE_3 ; PS51163 YRDC
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
2.6 %Cys (Translated Protein) 1.6 %Met (Translated Protein) 4.2 %Cys+Met (Translated Protein) 2.6 %Cys (Mature Protein) 1.6 %Met (Mature Protein) 4.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MELERVQISIQGLVQGVGFRPCVYKLAKQMELTGFVQNNASGVLIEIQGNYLSQFIPKLR CCCHHEEEEHHHHHHCCCCCHHHHHHHHHHHHHEEEECCCCEEEEEECCCHHHHHHHHHH EQLPPLAAIHNLEFTSLPIVPNERAFEILDSQQGKINTVITPDVCICSECLGELFDPQSR HHCCCHHHHHCCCCCCCCCCCCCHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHCCCCHH YYRYPFLNCTHCGPRFTITRNLPYDRCQTSMSQFPLCQSCQSDYLNPDNRRYHAQPTACS EEECCCCEECCCCCCEEEEECCCHHHHHHHHHHCCHHHHHHHHCCCCCCCEEECCCCHHH QCGPQLALSVDKVAQRIQEGEIIALKGLGGYQLICDARNEETISKLRLRKNREAKPFALM HCCCHHEEEHHHHHHHHCCCCEEEEECCCCEEEEEECCCHHHHHHHHHHCCCCCCCEEEE VANVKSAEEIAEVSCQARLVLESRERPIVLLRKKKAPLPDGIAPGLNHFGIMLPSTPLHY EECCCCHHHHHHHHHHHHEEECCCCCCEEEEECCCCCCCCCCCCCCCCCEEECCCCHHHH LLFNSFLGNPDYCQWLDEYHFMVLVVTSANIGGEPLIIDDKKAEQGLNSIADKIISHDRE HHHHHHCCCCHHHHHHHCCCEEEEEEEECCCCCCEEEEECCHHHHHHHHHHHHHHHCCCH IITRTDDSVVRMINDTSVLIRRARGYVPAPLRLPYEIPPTVALGGHLKNTFCITRGEEAF HEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCCCCEEEEECCHHHH VSQHIGSLNNKATIEYFHESLNHLLKFLAVKPERIAHDWHPDFYTSRLAQKYDIPVYGVQ HHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHCCCCEECCC HHHAHLASVAAEHGIQEPVLGLVLDGYGFGSDGEAWGGELLLLEKAEFKRVGHFFPIPQP HHHHHHHHHHHHCCCCCCCHHEEEECCCCCCCCCCCCCCEEEEECHHHHHCCCCCCCCCC GGELAAREPWRMAAGILHTLGRGDEISQRFKEQPQSPFLLQLLEKKIHCPLTTSCGRLFD CCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHH AVSALLGVESLSLFEGHAAMRLESMVTHPQVLNKGWTINGNVFDMRPTLQFIANTTDQQL HHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHCCCEEECCCEEECCHHHHHHHCCCHHHH GANLFHGTLIAGLSEWVTGVCREKGIHMLLLSGGCFLNRVLAEGLINSLIKSGIKPLLPK CHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHCHHHHHHH LLPPNDGGIALGQAWIVGIKE HCCCCCCCEEECCEEEEEECC >Mature Secondary Structure MELERVQISIQGLVQGVGFRPCVYKLAKQMELTGFVQNNASGVLIEIQGNYLSQFIPKLR CCCHHEEEEHHHHHHCCCCCHHHHHHHHHHHHHEEEECCCCEEEEEECCCHHHHHHHHHH EQLPPLAAIHNLEFTSLPIVPNERAFEILDSQQGKINTVITPDVCICSECLGELFDPQSR HHCCCHHHHHCCCCCCCCCCCCCHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHCCCCHH YYRYPFLNCTHCGPRFTITRNLPYDRCQTSMSQFPLCQSCQSDYLNPDNRRYHAQPTACS EEECCCCEECCCCCCEEEEECCCHHHHHHHHHHCCHHHHHHHHCCCCCCCEEECCCCHHH QCGPQLALSVDKVAQRIQEGEIIALKGLGGYQLICDARNEETISKLRLRKNREAKPFALM HCCCHHEEEHHHHHHHHCCCCEEEEECCCCEEEEEECCCHHHHHHHHHHCCCCCCCEEEE VANVKSAEEIAEVSCQARLVLESRERPIVLLRKKKAPLPDGIAPGLNHFGIMLPSTPLHY EECCCCHHHHHHHHHHHHEEECCCCCCEEEEECCCCCCCCCCCCCCCCCEEECCCCHHHH LLFNSFLGNPDYCQWLDEYHFMVLVVTSANIGGEPLIIDDKKAEQGLNSIADKIISHDRE HHHHHHCCCCHHHHHHHCCCEEEEEEEECCCCCCEEEEECCHHHHHHHHHHHHHHHCCCH IITRTDDSVVRMINDTSVLIRRARGYVPAPLRLPYEIPPTVALGGHLKNTFCITRGEEAF HEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCCCCEEEEECCHHHH VSQHIGSLNNKATIEYFHESLNHLLKFLAVKPERIAHDWHPDFYTSRLAQKYDIPVYGVQ HHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHCCCCEECCC HHHAHLASVAAEHGIQEPVLGLVLDGYGFGSDGEAWGGELLLLEKAEFKRVGHFFPIPQP HHHHHHHHHHHHCCCCCCCHHEEEECCCCCCCCCCCCCCEEEEECHHHHHCCCCCCCCCC GGELAAREPWRMAAGILHTLGRGDEISQRFKEQPQSPFLLQLLEKKIHCPLTTSCGRLFD CCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHH AVSALLGVESLSLFEGHAAMRLESMVTHPQVLNKGWTINGNVFDMRPTLQFIANTTDQQL HHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHCCCEEECCCEEECCHHHHHHHCCCHHHH GANLFHGTLIAGLSEWVTGVCREKGIHMLLLSGGCFLNRVLAEGLINSLIKSGIKPLLPK CHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHCHHHHHHH LLPPNDGGIALGQAWIVGIKE HCCCCCCCEEECCEEEEEECC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 9799289; 12948488 [H]