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The map label for this gene is shkA [H]

Identifier: 54295292

GI number: 54295292

Start: 2706836

End: 2708113

Strand: Reverse

Name: shkA [H]

Synonym: lpl2377

Alternate gene names: 54295292

Gene position: 2708113-2706836 (Counterclockwise)

Preceding gene: 54295293

Following gene: 54295291

Centisome position: 80.94

GC content: 37.09

Gene sequence:

>1278_bases
ATGAGTGATTATGAAGTATTGTTACGCCATCTTGATAGAGAGATACGTGCAAGGAAAGAAGCTGAAGAAATAAGTGAAAA
AAAAATATCCGAGTTATACCGTTTTGCCCAACGTCTGGAAGAGAGTTTAAGGGCTCAAAAAGAAATAAGTAAAAAATTAA
AAGAGAAGACCAAGGCATTAAAGCAGCAAATCGCTAAAACAGAAGAAGAACGACATGCCAAAAGTACTTTACAAACCATA
TTGGAAAGTGCAATTGAATATTCAATCATTGCAATCAATTTGAAAGGCGTCATCTTGGTTTGGAATGAAGGAGCAAGACG
AAATTACGGCTACGAGGCTCAAGAATTAGTGAACAAAGAGAGCATCGAGATTTTGCATACAGTGGAAGATATCCAATCAG
GTAAAGTAAGAAAATTTTTTCAAACGGTACGTCGGGAAGGAAAGGCAGAAGAAATATTTCAAAGGGTCAGAAAAGACGGG
TCCCAGTTCACTGCTTCCGTTACTATGACTATCCGCCATGATTCGCAAGGAAAAAAAGTAGGGTACGTCATTATTTCAAA
AGATATTACAGAAATTAAAGAATTTGAAGAAAAGCTGATTAAAAGTAACCAGGATCTTGAGGAGTTTTCATACATTATTT
CCCATGACCTAAAAGCGCCGCTAAGGGCAATTATCCAATTGGCAACATGGATTGAAGAGGATTGTGGAAATAAGTTGGAT
CCTCTTTCCAGAAAAAATCTTCAATTGCTTAGAGAACGTACCCGTCGCATGAGCGGGATGATAGATGGCTTATTACAATA
TGCGCGGGCAGGCAGGGTCAATATGGAGGTAGAATGGGTAGATACTAAGGAGTTAATTCAAGAAATAATAGATATTCTTA
ACCATGATGAACAATTTACTATCATTATCCATGGATCCATGCCCCAACTGCCAACAGCCAAATTACTTCTAAGCCAGGTT
TTTTCTAATCTGATAGCAAATAGCATGAAACATCATCATTGTAAAACAGGAACAATTGAGATTGGTGTTTTGGACAAAGG
CACATTTTATGAGTTTTTTGTGGCAGATGATGGTCCGGGTATTGAGCCAGTATATTTTGAGAAAATATTCAGAATATTTC
AAACCTTAAAACCCAAAGATGAGGCAGAAACTACCGGGATAGGGTTAACTATAGTAAAGAAAATTGTAGAATCTCAAAAT
GGGAAAATTCAGGTGGATTCTGAGTTAGGTAAAGGCGCAAGATTTTCATTTACATGGCCTAAAGTTCCTCATCAATAA

Upstream 100 bases:

>100_bases
TGTATTAAATATCATAAAGAAAACATGACTATTGTTCGTGAAAATCTGCCTGCAAAAACAGGTTTTAAGGTAAGATTTGT
ATTAACGAAAGGCGATCCTG

Downstream 100 bases:

>100_bases
AGGTTTAGGTCTATAATTAATTTAGAAATAAAAAATAAAATATTGTCTCACGGAGAATAATGATGGACCTCGCAGCTGAT
AAAGTAGATATCCTGTATTT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 425; Mature: 424

Protein sequence:

>425_residues
MSDYEVLLRHLDREIRARKEAEEISEKKISELYRFAQRLEESLRAQKEISKKLKEKTKALKQQIAKTEEERHAKSTLQTI
LESAIEYSIIAINLKGVILVWNEGARRNYGYEAQELVNKESIEILHTVEDIQSGKVRKFFQTVRREGKAEEIFQRVRKDG
SQFTASVTMTIRHDSQGKKVGYVIISKDITEIKEFEEKLIKSNQDLEEFSYIISHDLKAPLRAIIQLATWIEEDCGNKLD
PLSRKNLQLLRERTRRMSGMIDGLLQYARAGRVNMEVEWVDTKELIQEIIDILNHDEQFTIIIHGSMPQLPTAKLLLSQV
FSNLIANSMKHHHCKTGTIEIGVLDKGTFYEFFVADDGPGIEPVYFEKIFRIFQTLKPKDEAETTGIGLTIVKKIVESQN
GKIQVDSELGKGARFSFTWPKVPHQ

Sequences:

>Translated_425_residues
MSDYEVLLRHLDREIRARKEAEEISEKKISELYRFAQRLEESLRAQKEISKKLKEKTKALKQQIAKTEEERHAKSTLQTI
LESAIEYSIIAINLKGVILVWNEGARRNYGYEAQELVNKESIEILHTVEDIQSGKVRKFFQTVRREGKAEEIFQRVRKDG
SQFTASVTMTIRHDSQGKKVGYVIISKDITEIKEFEEKLIKSNQDLEEFSYIISHDLKAPLRAIIQLATWIEEDCGNKLD
PLSRKNLQLLRERTRRMSGMIDGLLQYARAGRVNMEVEWVDTKELIQEIIDILNHDEQFTIIIHGSMPQLPTAKLLLSQV
FSNLIANSMKHHHCKTGTIEIGVLDKGTFYEFFVADDGPGIEPVYFEKIFRIFQTLKPKDEAETTGIGLTIVKKIVESQN
GKIQVDSELGKGARFSFTWPKVPHQ
>Mature_424_residues
SDYEVLLRHLDREIRARKEAEEISEKKISELYRFAQRLEESLRAQKEISKKLKEKTKALKQQIAKTEEERHAKSTLQTIL
ESAIEYSIIAINLKGVILVWNEGARRNYGYEAQELVNKESIEILHTVEDIQSGKVRKFFQTVRREGKAEEIFQRVRKDGS
QFTASVTMTIRHDSQGKKVGYVIISKDITEIKEFEEKLIKSNQDLEEFSYIISHDLKAPLRAIIQLATWIEEDCGNKLDP
LSRKNLQLLRERTRRMSGMIDGLLQYARAGRVNMEVEWVDTKELIQEIIDILNHDEQFTIIIHGSMPQLPTAKLLLSQVF
SNLIANSMKHHHCKTGTIEIGVLDKGTFYEFFVADDGPGIEPVYFEKIFRIFQTLKPKDEAETTGIGLTIVKKIVESQNG
KIQVDSELGKGARFSFTWPKVPHQ

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1787894, Length=223, Percent_Identity=32.7354260089686, Blast_Score=85, Evalue=9e-18,
Organism=Escherichia coli, GI48994928, Length=272, Percent_Identity=26.1029411764706, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1790436, Length=232, Percent_Identity=26.7241379310345, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1788549, Length=368, Percent_Identity=23.3695652173913, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1786600, Length=249, Percent_Identity=27.3092369477912, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1786912, Length=217, Percent_Identity=26.2672811059908, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790346, Length=218, Percent_Identity=29.8165137614679, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR013654
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF00512 HisKA; PF08446 PAS_2; PF00360 Phytochrome [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 49047; Mature: 48916

Theoretical pI: Translated: 7.79; Mature: 7.79

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDYEVLLRHLDREIRARKEAEEISEKKISELYRFAQRLEESLRAQKEISKKLKEKTKAL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KQQIAKTEEERHAKSTLQTILESAIEYSIIAINLKGVILVWNEGARRNYGYEAQELVNKE
HHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEEECEEEEEECCCCCCCCCCCHHHHHCHH
SIEILHTVEDIQSGKVRKFFQTVRREGKAEEIFQRVRKDGSQFTASVTMTIRHDSQGKKV
HHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEEEEEEEECCCCCEE
GYVIISKDITEIKEFEEKLIKSNQDLEEFSYIISHDLKAPLRAIIQLATWIEEDCGNKLD
EEEEEECCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PLSRKNLQLLRERTRRMSGMIDGLLQYARAGRVNMEVEWVDTKELIQEIIDILNHDEQFT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHCCCCEEE
IIIHGSMPQLPTAKLLLSQVFSNLIANSMKHHHCKTGTIEIGVLDKGTFYEFFVADDGPG
EEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEEECCCCC
IEPVYFEKIFRIFQTLKPKDEAETTGIGLTIVKKIVESQNGKIQVDSELGKGARFSFTWP
CCHHHHHHHHHHHHHCCCCCCHHHCCCHHHHHHHHHHCCCCCEEEECCCCCCCEEEEECC
KVPHQ
CCCCC
>Mature Secondary Structure 
SDYEVLLRHLDREIRARKEAEEISEKKISELYRFAQRLEESLRAQKEISKKLKEKTKAL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KQQIAKTEEERHAKSTLQTILESAIEYSIIAINLKGVILVWNEGARRNYGYEAQELVNKE
HHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEEECEEEEEECCCCCCCCCCCHHHHHCHH
SIEILHTVEDIQSGKVRKFFQTVRREGKAEEIFQRVRKDGSQFTASVTMTIRHDSQGKKV
HHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEEEEEEEECCCCCEE
GYVIISKDITEIKEFEEKLIKSNQDLEEFSYIISHDLKAPLRAIIQLATWIEEDCGNKLD
EEEEEECCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PLSRKNLQLLRERTRRMSGMIDGLLQYARAGRVNMEVEWVDTKELIQEIIDILNHDEQFT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHCCCCEEE
IIIHGSMPQLPTAKLLLSQVFSNLIANSMKHHHCKTGTIEIGVLDKGTFYEFFVADDGPG
EEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEEECCCCC
IEPVYFEKIFRIFQTLKPKDEAETTGIGLTIVKKIVESQNGKIQVDSELGKGARFSFTWP
CCHHHHHHHHHHHHHCCCCCCHHHCCCHHHHHHHHHHCCCCCEEEECCCCCCCEEEEECC
KVPHQ
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]