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The map label for this gene is fadH [H]

Identifier: 54295189

GI number: 54295189

Start: 2586862

End: 2588886

Strand: Reverse

Name: fadH [H]

Synonym: lpl2269

Alternate gene names: 54295189

Gene position: 2588886-2586862 (Counterclockwise)

Preceding gene: 54295191

Following gene: 54295188

Centisome position: 77.38

GC content: 42.22

Gene sequence:

>2025_bases
ATGGAATTGAGAATTGATAATACCCCTTTTAAAGCCATTTTTCAGCCTTTGGATCTGGGCTTTACCCAAATTAAGAATCG
TTTATTGATGGGTTCAATGCACACTGGACTTGAGGAAGATAAAGAAAATTTAAATCGCCTGGCAAGCTTTTATAGAGAAA
GAGCTCAGGGTGGAGTTGGATTAATCGTAACGGGTGGTTTTGCTCCTAACCGAGCTGGCCGTCTGGCCCCCTTCGCGGCC
AAACTGACTAATAGTAAAGAGCAACATCGGCATGAAGTCATTACTCAAACGGTCCATGAAGCAGGTGGAAAAATTGCCTT
GCAAATATTGCATGCAGGGCGTTATGGTTATCACCCTTTTATTGTAGCGCCGAGCGGCATTAAATCTCCCATTAGCCCGT
TTAAACCGTGGGAAATGAGTAAAAGACGAATTATCAAAACCATCAAACATTTTGCCCGATGTGCCAGACTGGCTCAATTG
GCTGGCTATGATGGGGTTGAGATCATGGGAAGCGAAGGATATTTGATAAACCAGTTTATAGTCACTCATACCAATCATCG
AAGGGATGAATGGGGAGGCAGTTTCTCCAATCGCATTCGATTTCCTATTGAAATAGTTCGCAGTGTTCGTGAGGCGGTAG
GCGAGCACTTTATTATCATTTATCGCTTGTCCATGCTTGATTTAGTGGCTGAGGGGAGTAATTGGCAGGAAGTGGTTACC
CTCGCTAAAGCTATTGAGCAAGCTGGTGCCAGTTTAATCAATACGGGTATAGGTTGGCATGAAGCAAGAATTCCAACGAT
AGGAACGATGGTTCCATCTGCTGCCTTCACTCAAGTGACCCAGCATTTAAAGCCGGAAATTAAAATACCTGTAATTACAT
CTAACCGAATTAATACACCAGAATTGGCTAATCAACTATTAGAAGATGGGGTCGCAGATATGATCTCCATGGCCAGACCA
TTTCTAGCGGATCCCTGCTTTGCAGAAAAAGCAAAATTAGGCGAAAGCAAAGCGATTAATGTATGCATAGCTTGTAATCA
AGCATGTCTTGATCAAGTTTTTGTGAACAAAACGGCATCTTGCCTGGTTAATCCCCGCGCATGCAACGAGACAACCTTGG
TTTATGAAACGACAAATCAACCGAAAGCTATTGCTGTAGTTGGTTCTGGGCCAGCTGGCCTTGCTTTTGCTGTGACAGCC
GCCGAGCGAGGGCATAAAATTACCCTGTTTGAAAAAGCGAATCAGATTGGCGGGCAGTTTAATTTAGCGAAAAAAATTCC
TGGAAAAGAAGAGTTTCAGCATACCTTGAATTATTTTGCCTACCAGCTCCAAAAGTATAAAGTGGATGTACGTTTGAATA
CTGAAGCTACTGTGGAATTACTTAAAGACTATGATGAAGTGGTCTTGGCCAGTGGAATTATACCCAGAGTTCCCGAAATT
AAAGGCATAGATCATAAAAAGGTAGTGAGTTATATTGATGTGATTACTCAAAACAAACCCGTTGGTTCACGAGTTGCCGT
CATTGGGGCAGGAGGAATTGGTTTTGATGTCGCTGAGTTTTTAACTCATGATCATCAATTGACTTCCGAGCAATTTTATA
ATGAATGGGGAATTGATATTAGCGGGCAGCATAGAGGTGGATTAAAACCAGCTGAAATTGCACCGAGCCCTCGTGAAGTG
TATTTATTACAACGCAAAAAAGAAAAAATGGGTAAACGGTTGGGAAAAACTACCGGATGGATTCATCGCTCCAGTTTAAA
ACATAAACAAGTCAAAATGCTTTCGGGTGTAAATTACGAGCGTATTGATGATCAGGGATTGCACTTGACTATTGATGACA
AGCCTCAAGTTTTGGAGGTTGATTCTATAGTGATTTGCGCAGGCCAAATAGAATTAAAGAATTTGTATGAGCCTCTGAAA
ATGGCAGGCAAGTTGGTTCATTTAATAGGAGGCGCTTATAAAGCCTTAGAGCTTGACGCACGTCATGCTATTGATCAGGC
TTGTCGGTTGGCTGCATTAGTATGA

Upstream 100 bases:

>100_bases
GAGACGATTACAAATTAATTGAATCGGTAAAAAATGATTGCTGTATAATAAGCAAGGTTTATACTTTATCTTTTAAGCTT
TAATTAAACAGAGAGTCCTC

Downstream 100 bases:

>100_bases
GTAAAATTGCTGTAGTGATAAATCCTATAGCAGGCGGCGGTCGCGGTAAAAAAGTTTGGAAAGTCCTAAAACCCGGGTTA
CATGCCCTATTCGAACAAAC

Product: hypothetical protein

Products: NA

Alternate protein names: 2,4-dienoyl coenzyme A reductase [H]

Number of amino acids: Translated: 674; Mature: 674

Protein sequence:

>674_residues
MELRIDNTPFKAIFQPLDLGFTQIKNRLLMGSMHTGLEEDKENLNRLASFYRERAQGGVGLIVTGGFAPNRAGRLAPFAA
KLTNSKEQHRHEVITQTVHEAGGKIALQILHAGRYGYHPFIVAPSGIKSPISPFKPWEMSKRRIIKTIKHFARCARLAQL
AGYDGVEIMGSEGYLINQFIVTHTNHRRDEWGGSFSNRIRFPIEIVRSVREAVGEHFIIIYRLSMLDLVAEGSNWQEVVT
LAKAIEQAGASLINTGIGWHEARIPTIGTMVPSAAFTQVTQHLKPEIKIPVITSNRINTPELANQLLEDGVADMISMARP
FLADPCFAEKAKLGESKAINVCIACNQACLDQVFVNKTASCLVNPRACNETTLVYETTNQPKAIAVVGSGPAGLAFAVTA
AERGHKITLFEKANQIGGQFNLAKKIPGKEEFQHTLNYFAYQLQKYKVDVRLNTEATVELLKDYDEVVLASGIIPRVPEI
KGIDHKKVVSYIDVITQNKPVGSRVAVIGAGGIGFDVAEFLTHDHQLTSEQFYNEWGIDISGQHRGGLKPAEIAPSPREV
YLLQRKKEKMGKRLGKTTGWIHRSSLKHKQVKMLSGVNYERIDDQGLHLTIDDKPQVLEVDSIVICAGQIELKNLYEPLK
MAGKLVHLIGGAYKALELDARHAIDQACRLAALV

Sequences:

>Translated_674_residues
MELRIDNTPFKAIFQPLDLGFTQIKNRLLMGSMHTGLEEDKENLNRLASFYRERAQGGVGLIVTGGFAPNRAGRLAPFAA
KLTNSKEQHRHEVITQTVHEAGGKIALQILHAGRYGYHPFIVAPSGIKSPISPFKPWEMSKRRIIKTIKHFARCARLAQL
AGYDGVEIMGSEGYLINQFIVTHTNHRRDEWGGSFSNRIRFPIEIVRSVREAVGEHFIIIYRLSMLDLVAEGSNWQEVVT
LAKAIEQAGASLINTGIGWHEARIPTIGTMVPSAAFTQVTQHLKPEIKIPVITSNRINTPELANQLLEDGVADMISMARP
FLADPCFAEKAKLGESKAINVCIACNQACLDQVFVNKTASCLVNPRACNETTLVYETTNQPKAIAVVGSGPAGLAFAVTA
AERGHKITLFEKANQIGGQFNLAKKIPGKEEFQHTLNYFAYQLQKYKVDVRLNTEATVELLKDYDEVVLASGIIPRVPEI
KGIDHKKVVSYIDVITQNKPVGSRVAVIGAGGIGFDVAEFLTHDHQLTSEQFYNEWGIDISGQHRGGLKPAEIAPSPREV
YLLQRKKEKMGKRLGKTTGWIHRSSLKHKQVKMLSGVNYERIDDQGLHLTIDDKPQVLEVDSIVICAGQIELKNLYEPLK
MAGKLVHLIGGAYKALELDARHAIDQACRLAALV
>Mature_674_residues
MELRIDNTPFKAIFQPLDLGFTQIKNRLLMGSMHTGLEEDKENLNRLASFYRERAQGGVGLIVTGGFAPNRAGRLAPFAA
KLTNSKEQHRHEVITQTVHEAGGKIALQILHAGRYGYHPFIVAPSGIKSPISPFKPWEMSKRRIIKTIKHFARCARLAQL
AGYDGVEIMGSEGYLINQFIVTHTNHRRDEWGGSFSNRIRFPIEIVRSVREAVGEHFIIIYRLSMLDLVAEGSNWQEVVT
LAKAIEQAGASLINTGIGWHEARIPTIGTMVPSAAFTQVTQHLKPEIKIPVITSNRINTPELANQLLEDGVADMISMARP
FLADPCFAEKAKLGESKAINVCIACNQACLDQVFVNKTASCLVNPRACNETTLVYETTNQPKAIAVVGSGPAGLAFAVTA
AERGHKITLFEKANQIGGQFNLAKKIPGKEEFQHTLNYFAYQLQKYKVDVRLNTEATVELLKDYDEVVLASGIIPRVPEI
KGIDHKKVVSYIDVITQNKPVGSRVAVIGAGGIGFDVAEFLTHDHQLTSEQFYNEWGIDISGQHRGGLKPAEIAPSPREV
YLLQRKKEKMGKRLGKTTGWIHRSSLKHKQVKMLSGVNYERIDDQGLHLTIDDKPQVLEVDSIVICAGQIELKNLYEPLK
MAGKLVHLIGGAYKALELDARHAIDQACRLAALV

Specific function: Catalyzes the NADP-dependent reduction of 2,4-dienoyl- CoA to yield trans-2- enoyl-CoA [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789463, Length=667, Percent_Identity=56.9715142428786, Blast_Score=787, Evalue=0.0,
Organism=Escherichia coli, GI1787939, Length=354, Percent_Identity=25.1412429378531, Blast_Score=79, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17559802, Length=310, Percent_Identity=24.5161290322581, Blast_Score=85, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17565138, Length=299, Percent_Identity=23.7458193979933, Blast_Score=82, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17540738, Length=305, Percent_Identity=24.2622950819672, Blast_Score=82, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17564188, Length=307, Percent_Identity=22.8013029315961, Blast_Score=79, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17566914, Length=315, Percent_Identity=23.4920634920635, Blast_Score=77, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI72001454, Length=339, Percent_Identity=22.1238938053097, Blast_Score=76, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17559804, Length=317, Percent_Identity=23.0283911671924, Blast_Score=76, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6325086, Length=226, Percent_Identity=27.8761061946903, Blast_Score=82, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6321973, Length=225, Percent_Identity=26.6666666666667, Blast_Score=81, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR013027
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN; PF07992 Pyr_redox_2 [H]

EC number: =1.3.1.34 [H]

Molecular weight: Translated: 74589; Mature: 74589

Theoretical pI: Translated: 9.17; Mature: 9.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELRIDNTPFKAIFQPLDLGFTQIKNRLLMGSMHTGLEEDKENLNRLASFYRERAQGGVG
CEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCEE
LIVTGGFAPNRAGRLAPFAAKLTNSKEQHRHEVITQTVHEAGGKIALQILHAGRYGYHPF
EEEECCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCE
IVAPSGIKSPISPFKPWEMSKRRIIKTIKHFARCARLAQLAGYDGVEIMGSEGYLINQFI
EECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEEEEEE
VTHTNHRRDEWGGSFSNRIRFPIEIVRSVREAVGEHFIIIYRLSMLDLVAEGSNWQEVVT
EECCCCCCHHCCCCHHCCCCCHHHHHHHHHHHHCCCEEEEEHHHHHHHHHCCCCHHHHHH
LAKAIEQAGASLINTGIGWHEARIPTIGTMVPSAAFTQVTQHLKPEIKIPVITSNRINTP
HHHHHHHHCHHHHHCCCCCCCCCCCCHHHHCCHHHHHHHHHHCCCCEEEEEEECCCCCCH
ELANQLLEDGVADMISMARPFLADPCFAEKAKLGESKAINVCIACNQACLDQVFVNKTAS
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCEEEEEEECCHHHHHHHHHCCCHH
CLVNPRACNETTLVYETTNQPKAIAVVGSGPAGLAFAVTAAERGHKITLFEKANQIGGQF
HEECCCCCCCCEEEEEECCCCCEEEEEECCCCCEEEEEEECCCCCEEEEEECHHHCCCCE
NLAKKIPGKEEFQHTLNYFAYQLQKYKVDVRLNTEATVELLKDYDEVVLASGIIPRVPEI
EEHHCCCCHHHHHHHHHHHHHHHHHEEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCC
KGIDHKKVVSYIDVITQNKPVGSRVAVIGAGGIGFDVAEFLTHDHQLTSEQFYNEWGIDI
CCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHCCHHHHHHHHHHHCCCEE
SGQHRGGLKPAEIAPSPREVYLLQRKKEKMGKRLGKTTGWIHRSSLKHKQVKMLSGVNYE
CCCCCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHCCHHCCEEHHHCHHHHHHHHHCCCHH
RIDDQGLHLTIDDKPQVLEVDSIVICAGQIELKNLYEPLKMAGKLVHLIGGAYKALELDA
CCCCCCCEEEECCCCCEEEECEEEEEECCEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
RHAIDQACRLAALV
HHHHHHHHHHHHCC
>Mature Secondary Structure
MELRIDNTPFKAIFQPLDLGFTQIKNRLLMGSMHTGLEEDKENLNRLASFYRERAQGGVG
CEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCEE
LIVTGGFAPNRAGRLAPFAAKLTNSKEQHRHEVITQTVHEAGGKIALQILHAGRYGYHPF
EEEECCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCE
IVAPSGIKSPISPFKPWEMSKRRIIKTIKHFARCARLAQLAGYDGVEIMGSEGYLINQFI
EECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEEEEEE
VTHTNHRRDEWGGSFSNRIRFPIEIVRSVREAVGEHFIIIYRLSMLDLVAEGSNWQEVVT
EECCCCCCHHCCCCHHCCCCCHHHHHHHHHHHHCCCEEEEEHHHHHHHHHCCCCHHHHHH
LAKAIEQAGASLINTGIGWHEARIPTIGTMVPSAAFTQVTQHLKPEIKIPVITSNRINTP
HHHHHHHHCHHHHHCCCCCCCCCCCCHHHHCCHHHHHHHHHHCCCCEEEEEEECCCCCCH
ELANQLLEDGVADMISMARPFLADPCFAEKAKLGESKAINVCIACNQACLDQVFVNKTAS
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCEEEEEEECCHHHHHHHHHCCCHH
CLVNPRACNETTLVYETTNQPKAIAVVGSGPAGLAFAVTAAERGHKITLFEKANQIGGQF
HEECCCCCCCCEEEEEECCCCCEEEEEECCCCCEEEEEEECCCCCEEEEEECHHHCCCCE
NLAKKIPGKEEFQHTLNYFAYQLQKYKVDVRLNTEATVELLKDYDEVVLASGIIPRVPEI
EEHHCCCCHHHHHHHHHHHHHHHHHEEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCC
KGIDHKKVVSYIDVITQNKPVGSRVAVIGAGGIGFDVAEFLTHDHQLTSEQFYNEWGIDI
CCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHCCHHHHHHHHHHHCCCEE
SGQHRGGLKPAEIAPSPREVYLLQRKKEKMGKRLGKTTGWIHRSSLKHKQVKMLSGVNYE
CCCCCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHCCHHCCEEHHHCHHHHHHHHHCCCHH
RIDDQGLHLTIDDKPQVLEVDSIVICAGQIELKNLYEPLKMAGKLVHLIGGAYKALELDA
CCCCCCCEEEECCCCCEEEECEEEEEECCEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
RHAIDQACRLAALV
HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9346310; 9278503 [H]