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The map label for this gene is ugpQ [H]

Identifier: 54295120

GI number: 54295120

Start: 2514882

End: 2515601

Strand: Reverse

Name: ugpQ [H]

Synonym: lpl2200

Alternate gene names: 54295120

Gene position: 2515601-2514882 (Counterclockwise)

Preceding gene: 54295121

Following gene: 54295119

Centisome position: 75.19

GC content: 40.56

Gene sequence:

>720_bases
TTGATCCTTGAAAAAATTATCGGTCACCGGGGAGCATCGGGTTATGCTCCAGAAAATACGATGGCGTCTTTTAATAAAGC
ATTGTCTTTAGGTTGTCGTTTCATTGAGTTTGATGTGATGTGCAGCCTTGATGGTGAACCTTTTATCATTCACGATGACA
ATTTGAAACGAACCACGAATGGAAAAGGAGAGGTGGGACTGGTGGAGGCAGATTATCTCCGTGGTCTTGATGCTGGCTCT
TGGTATTCGAAGCAGTATAAGGGAGAAAAAATTCCACACTTTACTGACGTATTAAAGTGGTTATCTTTTTCCGATGTCCA
GGCGAACATAGAAATAAAACCTTATCCTGGAACGGTTGAGCAAACTACTGTATCAGTGCTAAGTCATATCCATCGGCATT
GGCCCCAAAATAAAGAATTACCTCTCGTTTCCTGTTTTGAATGGGATGCTTTGGTATTATGCCGCAGTATTGCTCCAGAA
ATGCCTTTAGGGTTCTTGCTGCATGAGTGGGATAAAGATTGGTTACAGAAGGCGAAACAATTGGAATGTTATTCAATACA
TTTCAATAGAAAGATATTAACCGCTGATCGAGTGAAGGCAGTTAAGGATCAAGGCTATGTAGTATGCGCCTATACTGTAA
ACCGTAAACGTTTGGCCAAAAAGTTATTTGATTGGGGTGTTGATGCTCTCTTTAGTGATTATCCAGACTTGTTAAAATGA

Upstream 100 bases:

>100_bases
GCGATGGCTGCTGCTCCGGCACCATTGACAGTGAGTAATGAATTAATATTGACCGCTATGGTAGAAGCAGCATCCAATCG
CAAACAGGGAGATTAATTAG

Downstream 100 bases:

>100_bases
AAATACTCTTTTTGCTTTTGTTAATTTTTCTGAGTGTCATTCCTGCGCAGGCCAAACCAGTTGAGCTGGTTTTTTGGCAT
GCGATGGCAGGGCATTTGGG

Product: hypothetical protein

Products: NA

Alternate protein names: Glycerophosphodiester phosphodiesterase [H]

Number of amino acids: Translated: 239; Mature: 239

Protein sequence:

>239_residues
MILEKIIGHRGASGYAPENTMASFNKALSLGCRFIEFDVMCSLDGEPFIIHDDNLKRTTNGKGEVGLVEADYLRGLDAGS
WYSKQYKGEKIPHFTDVLKWLSFSDVQANIEIKPYPGTVEQTTVSVLSHIHRHWPQNKELPLVSCFEWDALVLCRSIAPE
MPLGFLLHEWDKDWLQKAKQLECYSIHFNRKILTADRVKAVKDQGYVVCAYTVNRKRLAKKLFDWGVDALFSDYPDLLK

Sequences:

>Translated_239_residues
MILEKIIGHRGASGYAPENTMASFNKALSLGCRFIEFDVMCSLDGEPFIIHDDNLKRTTNGKGEVGLVEADYLRGLDAGS
WYSKQYKGEKIPHFTDVLKWLSFSDVQANIEIKPYPGTVEQTTVSVLSHIHRHWPQNKELPLVSCFEWDALVLCRSIAPE
MPLGFLLHEWDKDWLQKAKQLECYSIHFNRKILTADRVKAVKDQGYVVCAYTVNRKRLAKKLFDWGVDALFSDYPDLLK
>Mature_239_residues
MILEKIIGHRGASGYAPENTMASFNKALSLGCRFIEFDVMCSLDGEPFIIHDDNLKRTTNGKGEVGLVEADYLRGLDAGS
WYSKQYKGEKIPHFTDVLKWLSFSDVQANIEIKPYPGTVEQTTVSVLSHIHRHWPQNKELPLVSCFEWDALVLCRSIAPE
MPLGFLLHEWDKDWLQKAKQLECYSIHFNRKILTADRVKAVKDQGYVVCAYTVNRKRLAKKLFDWGVDALFSDYPDLLK

Specific function: Glycerophosphoryl diester phosphodiesterase hydrolyzes deacylated phospholipids to G3P and the corresponding alcohols [H]

COG id: COG0584

COG function: function code C; Glycerophosphoryl diester phosphodiesterase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycerophosphoryl diester phosphodiesterase family [H]

Homologues:

Organism=Homo sapiens, GI33457301, Length=88, Percent_Identity=45.4545454545455, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI284055245, Length=85, Percent_Identity=42.3529411764706, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI284055240, Length=85, Percent_Identity=42.3529411764706, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI189571657, Length=258, Percent_Identity=25.1937984496124, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI21361649, Length=85, Percent_Identity=42.3529411764706, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI284055242, Length=85, Percent_Identity=42.3529411764706, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1789858, Length=234, Percent_Identity=43.5897435897436, Blast_Score=191, Evalue=3e-50,
Organism=Caenorhabditis elegans, GI17542344, Length=119, Percent_Identity=34.453781512605, Blast_Score=73, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004129
- InterPro:   IPR017946 [H]

Pfam domain/function: PF03009 GDPD [H]

EC number: =3.1.4.46 [H]

Molecular weight: Translated: 27371; Mature: 27371

Theoretical pI: Translated: 7.20; Mature: 7.20

Prosite motif: PS50007 PIPLC_X_DOMAIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILEKIIGHRGASGYAPENTMASFNKALSLGCRFIEFDVMCSLDGEPFIIHDDNLKRTTN
CCHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCEEEEEEEEEECCCCEEEEECCCCCCCCC
GKGEVGLVEADYLRGLDAGSWYSKQYKGEKIPHFTDVLKWLSFSDVQANIEIKPYPGTVE
CCCCEEEEEHHHHCCCCCCCCHHHHCCCCCCCCHHHHHHHHCCCCCEEEEEEECCCCCHH
QTTVSVLSHIHRHWPQNKELPLVSCFEWDALVLCRSIAPEMPLGFLLHEWDKDWLQKAKQ
HHHHHHHHHHHHHCCCCCCCCEEEECCHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHC
LECYSIHFNRKILTADRVKAVKDQGYVVCAYTVNRKRLAKKLFDWGVDALFSDYPDLLK
CEEEEEEECCEEECHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHCHHHHHHCCHHHCC
>Mature Secondary Structure
MILEKIIGHRGASGYAPENTMASFNKALSLGCRFIEFDVMCSLDGEPFIIHDDNLKRTTN
CCHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCEEEEEEEEEECCCCEEEEECCCCCCCCC
GKGEVGLVEADYLRGLDAGSWYSKQYKGEKIPHFTDVLKWLSFSDVQANIEIKPYPGTVE
CCCCEEEEEHHHHCCCCCCCCHHHHCCCCCCCCHHHHHHHHCCCCCEEEEEEECCCCCHH
QTTVSVLSHIHRHWPQNKELPLVSCFEWDALVLCRSIAPEMPLGFLLHEWDKDWLQKAKQ
HHHHHHHHHHHHHCCCCCCCCEEEECCHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHC
LECYSIHFNRKILTADRVKAVKDQGYVVCAYTVNRKRLAKKLFDWGVDALFSDYPDLLK
CEEEEEEECCEEECHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHCHHHHHHCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2541415; 1851953; 8041620; 9278503; 3062310 [H]