Click here to switch to the map view.

The map label for this gene is yegE [H]

Identifier: 54294982

GI number: 54294982

Start: 2318845

End: 2320383

Strand: Reverse

Name: yegE [H]

Synonym: lpl2061

Alternate gene names: 54294982

Gene position: 2320383-2318845 (Counterclockwise)

Preceding gene: 54294984

Following gene: 54294979

Centisome position: 69.35

GC content: 32.88

Gene sequence:

>1539_bases
ATGCAAAATGCCAATGCAAAGATTCAAAATATAAATGAAATAATGTTTTCAGATCGCGTAATGTTACTAAATAAAAATTT
ATTAGTGAGCATTCCTGCAAATTTTTTATGTGCATTAATTATTTATATTGATTTCAATAAAACAACAACAGATCAAGAAA
TGCTCTCAGTATGGTTTATGGTTGGAGTAACAGTATTTGCTCTGCATGGAGGTTTATTTTTGTTTAATTATTATCGTCCC
TTGCCATCCAAATACCTTTTAAAATGGTTAATAAGCGTCACTGCGATTTATGGGGCTCTATGGGGAATAGCAGGCTCTGT
TCTTATTCCCCAGAATGATCTGTTAAATCAAATGATTGTCATAATTATAATTATTGGAATCGCATCAGGTGGATTACATA
TTCTTCAGCCCAGCTTTTTAGCAAGTCTATTATTTTTTACATTAACTCTTATTCCTCTATGCGTCTGGTTTTTCCAGCAA
AATACCCTTAACTATTGGTTCCTTGGAACTGCATTGCTGATTTACTTTTGTTTTTTATCAATTATATCCTGGATGGGATA
TGGACTTCTTAATAAGAATTTTAAATTACGTTATGAAAATTTGGATTTAATTAATAAATTGTATGCAATTAACGCTAATT
TGGAGGAAAGTGAGTTACGTTTCCGCTCCGCATTTAATTCTGCTGCTATTGGTATGGCTATAGTTTCTTTGGAGGGGATG
TGGTTAAAGGTTAACCAATCGCTTTGTCAGATTGTAGGATACTCAGAAGAAGAATTATTGGAAACTAATTTTCAATCGAT
CACATATCCAGAGGATTTAGAGCTCGATTTGGGCTATGTGAGGCAATTATTAGAGGGGGATATAAGATTCTATCATATGG
AAAAACGCTATATTCATAAAAATGGTAGTATCATTTGGATTTTACTTAGTGCTTCTTTAATCCGAGATGCCGAGAATAAA
CCACTCTATTTTATCTCGCAAATTCAAAACATTGATGCTCAAAAACGAGCAGAGCAAGAACTTCAACACATCGCATATCA
TGACACTTTAACTGGTTTGGGAAATAGAAAGCTATTAGAGTTATCATTTGACCAGGCATTAGCTCATGCGAAACGTCACC
AAACGCAAATTGCTATTATGTTTATGGATTTGGATTATTTTAAAAATGTGAATGACAAATTGGGTCATGATATTGGGGAT
CTTTTATTAGTTGAGATTGGAAAAAGATTACAGACTATTTTAAGGTCTACTGATCTAATTGTCAGGCATGGTGGTGATGA
ATTCATCATCGCGCTTACTGAATTATCCAATGTAAATCAAGTTATAGAAATAGCAAATAAAATTCTAATTGCTGTAAGCA
AGCCTATAACAATCAAACGTTATGGTATTTCAATTACAGGCAGTATGGGTATAAGTATCTATCCATATGACGGCGATGAT
TCAGATACATTAATTAGAAAAGCTGATGAAGCATTATATAGGGTGAAAATAGGGGGAAAAAATAATTTTCAATTGTTCAA
TACCGCACTACATAAGTAA

Upstream 100 bases:

>100_bases
TAACAATTAAGTATTTTTGTACTATATTAATACAATATATTAATACAATAGGGTTCAAATTGAGGTTTTGAATTTGTCAC
TTTATCTCAGTGAGCGCTGA

Downstream 100 bases:

>100_bases
AATAATTTTTTAATCAACAAGCTTCTTTCCAGCCCCTTTGTTCTTAGTTTGTCAGATTATTACCCGGTTTCCTCTCTAAA
TATCAACATTGCCATTTTCT

Product: hypothetical protein

Products: NA

Alternate protein names: DGC [H]

Number of amino acids: Translated: 512; Mature: 512

Protein sequence:

>512_residues
MQNANAKIQNINEIMFSDRVMLLNKNLLVSIPANFLCALIIYIDFNKTTTDQEMLSVWFMVGVTVFALHGGLFLFNYYRP
LPSKYLLKWLISVTAIYGALWGIAGSVLIPQNDLLNQMIVIIIIIGIASGGLHILQPSFLASLLFFTLTLIPLCVWFFQQ
NTLNYWFLGTALLIYFCFLSIISWMGYGLLNKNFKLRYENLDLINKLYAINANLEESELRFRSAFNSAAIGMAIVSLEGM
WLKVNQSLCQIVGYSEEELLETNFQSITYPEDLELDLGYVRQLLEGDIRFYHMEKRYIHKNGSIIWILLSASLIRDAENK
PLYFISQIQNIDAQKRAEQELQHIAYHDTLTGLGNRKLLELSFDQALAHAKRHQTQIAIMFMDLDYFKNVNDKLGHDIGD
LLLVEIGKRLQTILRSTDLIVRHGGDEFIIALTELSNVNQVIEIANKILIAVSKPITIKRYGISITGSMGISIYPYDGDD
SDTLIRKADEALYRVKIGGKNNFQLFNTALHK

Sequences:

>Translated_512_residues
MQNANAKIQNINEIMFSDRVMLLNKNLLVSIPANFLCALIIYIDFNKTTTDQEMLSVWFMVGVTVFALHGGLFLFNYYRP
LPSKYLLKWLISVTAIYGALWGIAGSVLIPQNDLLNQMIVIIIIIGIASGGLHILQPSFLASLLFFTLTLIPLCVWFFQQ
NTLNYWFLGTALLIYFCFLSIISWMGYGLLNKNFKLRYENLDLINKLYAINANLEESELRFRSAFNSAAIGMAIVSLEGM
WLKVNQSLCQIVGYSEEELLETNFQSITYPEDLELDLGYVRQLLEGDIRFYHMEKRYIHKNGSIIWILLSASLIRDAENK
PLYFISQIQNIDAQKRAEQELQHIAYHDTLTGLGNRKLLELSFDQALAHAKRHQTQIAIMFMDLDYFKNVNDKLGHDIGD
LLLVEIGKRLQTILRSTDLIVRHGGDEFIIALTELSNVNQVIEIANKILIAVSKPITIKRYGISITGSMGISIYPYDGDD
SDTLIRKADEALYRVKIGGKNNFQLFNTALHK
>Mature_512_residues
MQNANAKIQNINEIMFSDRVMLLNKNLLVSIPANFLCALIIYIDFNKTTTDQEMLSVWFMVGVTVFALHGGLFLFNYYRP
LPSKYLLKWLISVTAIYGALWGIAGSVLIPQNDLLNQMIVIIIIIGIASGGLHILQPSFLASLLFFTLTLIPLCVWFFQQ
NTLNYWFLGTALLIYFCFLSIISWMGYGLLNKNFKLRYENLDLINKLYAINANLEESELRFRSAFNSAAIGMAIVSLEGM
WLKVNQSLCQIVGYSEEELLETNFQSITYPEDLELDLGYVRQLLEGDIRFYHMEKRYIHKNGSIIWILLSASLIRDAENK
PLYFISQIQNIDAQKRAEQELQHIAYHDTLTGLGNRKLLELSFDQALAHAKRHQTQIAIMFMDLDYFKNVNDKLGHDIGD
LLLVEIGKRLQTILRSTDLIVRHGGDEFIIALTELSNVNQVIEIANKILIAVSKPITIKRYGISITGSMGISIYPYDGDD
SDTLIRKADEALYRVKIGGKNNFQLFNTALHK

Specific function: Cyclic-di-GMP is a second messenger which controls cell surface-associated traits in bacteria [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PAS (PER-ARNT-SIM) domains [H]

Homologues:

Organism=Escherichia coli, GI1788381, Length=148, Percent_Identity=47.972972972973, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1787541, Length=191, Percent_Identity=31.9371727748691, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI145693134, Length=205, Percent_Identity=35.609756097561, Blast_Score=110, Evalue=3e-25,
Organism=Escherichia coli, GI87081881, Length=305, Percent_Identity=28.1967213114754, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1786584, Length=195, Percent_Identity=28.7179487179487, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI87082007, Length=170, Percent_Identity=35.2941176470588, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI87081977, Length=169, Percent_Identity=32.5443786982249, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1787802, Length=144, Percent_Identity=34.0277777777778, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1787816, Length=155, Percent_Identity=34.8387096774194, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1787262, Length=165, Percent_Identity=31.5151515151515, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI87081921, Length=180, Percent_Identity=28.3333333333333, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788956, Length=158, Percent_Identity=29.746835443038, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI87081974, Length=149, Percent_Identity=30.8724832214765, Blast_Score=69, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR007895
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013656
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF05231 MASE1; PF08447 PAS_3; PF08448 PAS_4 [H]

EC number: =2.7.7.65 [H]

Molecular weight: Translated: 58397; Mature: 58397

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNANAKIQNINEIMFSDRVMLLNKNLLVSIPANFLCALIIYIDFNKTTTDQEMLSVWFM
CCCCCCHHHHHHHHHHCCEEEEEECCEEEECCHHHHEEEEEEEECCCCCCHHHHHHHHHH
VGVTVFALHGGLFLFNYYRPLPSKYLLKWLISVTAIYGALWGIAGSVLIPQNDLLNQMIV
HHHHHHHHHCCHHEEHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCEECCCHHHHHHHHH
IIIIIGIASGGLHILQPSFLASLLFFTLTLIPLCVWFFQQNTLNYWFLGTALLIYFCFLS
HHHHHHHCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHH
IISWMGYGLLNKNFKLRYENLDLINKLYAINANLEESELRFRSAFNSAAIGMAIVSLEGM
HHHHHCCHHCCCCCEEEECCHHHHHHHEEECCCCCHHHHHHHHHHCCHHHHHHEEEECCE
WLKVNQSLCQIVGYSEEELLETNFQSITYPEDLELDLGYVRQLLEGDIRFYHMEKRYIHK
EEEECHHHHHHHCCCHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCEEEEEEEHHHEEC
NGSIIWILLSASLIRDAENKPLYFISQIQNIDAQKRAEQELQHIAYHDTLTGLGNRKLLE
CCCEEEEEEEHHHHHCCCCCCEEEEHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEE
LSFDQALAHAKRHQTQIAIMFMDLDYFKNVNDKLGHDIGDLLLVEIGKRLQTILRSTDLI
EEHHHHHHHHHHCCCEEEEEEEECHHHHCCCHHHCCCHHHHHHHHHHHHHHHHHHCCCEE
VRHGGDEFIIALTELSNVNQVIEIANKILIAVSKPITIKRYGISITGSMGISIYPYDGDD
EEECCCEEEEEEECCCCHHHHHHHHHHEEEEECCCEEEEEECEEEEECCCEEEEECCCCC
SDTLIRKADEALYRVKIGGKNNFQLFNTALHK
CHHHHHHHHHCEEEEEECCCCCHHHHHHHHCC
>Mature Secondary Structure
MQNANAKIQNINEIMFSDRVMLLNKNLLVSIPANFLCALIIYIDFNKTTTDQEMLSVWFM
CCCCCCHHHHHHHHHHCCEEEEEECCEEEECCHHHHEEEEEEEECCCCCCHHHHHHHHHH
VGVTVFALHGGLFLFNYYRPLPSKYLLKWLISVTAIYGALWGIAGSVLIPQNDLLNQMIV
HHHHHHHHHCCHHEEHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCEECCCHHHHHHHHH
IIIIIGIASGGLHILQPSFLASLLFFTLTLIPLCVWFFQQNTLNYWFLGTALLIYFCFLS
HHHHHHHCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHH
IISWMGYGLLNKNFKLRYENLDLINKLYAINANLEESELRFRSAFNSAAIGMAIVSLEGM
HHHHHCCHHCCCCCEEEECCHHHHHHHEEECCCCCHHHHHHHHHHCCHHHHHHEEEECCE
WLKVNQSLCQIVGYSEEELLETNFQSITYPEDLELDLGYVRQLLEGDIRFYHMEKRYIHK
EEEECHHHHHHHCCCHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCEEEEEEEHHHEEC
NGSIIWILLSASLIRDAENKPLYFISQIQNIDAQKRAEQELQHIAYHDTLTGLGNRKLLE
CCCEEEEEEEHHHHHCCCCCCEEEEHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEE
LSFDQALAHAKRHQTQIAIMFMDLDYFKNVNDKLGHDIGDLLLVEIGKRLQTILRSTDLI
EEHHHHHHHHHHCCCEEEEEEEECHHHHCCCHHHCCCHHHHHHHHHHHHHHHHHHCCCEE
VRHGGDEFIIALTELSNVNQVIEIANKILIAVSKPITIKRYGISITGSMGISIYPYDGDD
EEECCCEEEEEEECCCCHHHHHHHHHHEEEEECCCEEEEEECEEEEECCCEEEEECCCCC
SDTLIRKADEALYRVKIGGKNNFQLFNTALHK
CHHHHHHHHHCEEEEEECCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 6094528; 7984428 [H]