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The map label for this gene is 54294939

Identifier: 54294939

GI number: 54294939

Start: 2262942

End: 2263889

Strand: Reverse

Name: 54294939

Synonym: lpl2018

Alternate gene names: NA

Gene position: 2263889-2262942 (Counterclockwise)

Preceding gene: 54294940

Following gene: 54294938

Centisome position: 67.67

GC content: 37.45

Gene sequence:

>948_bases
ATGCATTGGTTTGCTCAGGCACCAGCTAATATTGCTTTGATCAAATATATGGGTAAAAAGGATGAAAATTCCAATTTACC
TGATAATTCATCTCTATCTTACACCTTGAGTAATTTATTAAGTTCCGTGAAATTAGAGAGGTTACCGACTAAAAAAGACA
TTTGGGAACCACTTACTATTCCTGGAGCACCAGAATTTAACCTGTCAGTTGAAGCGCAAAAACGGTTTATTGATCATTTA
GTACGATTGAAAGAGTATTTTGGATATGTCGGTGGGTTTTTAATTCAATCCAGTAATAATTTCCCTCATAGCAGTGGTTT
AGCGAGTTCTGCCTCCAGCTTTGCTGCCTTGACAAAGTGTGCATCAATTGCATTAAGTGAACTCACTCAAAAACCTTTGC
CTTCTATTGATGAGCAAGCACAATGGAGTCGATTAGGTTCAGGCTCATCATGCCGTTCTTTTTATGCACCATGGGCGTTA
TGGACGGGCGATAAAGTCTCTGCAATCGATTTGCCTTATAAAGATCTATTACACCAAGTCATAGTAATTAGCAGTCAGGA
AAAAGAAATACCATCAAGGGTAGCGCATAAGCTGGTTAAAACAAGTCCTTTTTATGAAACGCGAAGCGAAAGGGCCGAGG
CAAATTTGAAGTTGTTACTGAACGCTTTTGAAAACAAAGATTGGACGAGTATATACCAAATTTGCTGGCATGAATTTCTC
GACATGCATCAATTATTTAAAACCTGTGAAAAACCATTTTCTTACATTACAGATAATACTTTGCATATATTGAGCGTTAT
TGAAAAATTTTGGAACGAGAAAGGTGATGGCCCCGTAGTTACTATGGATGCTGGTCCTAATGTTCATTTGCTTTATAGAT
CAGATCAAACAGATCTCGCACGACAATTTAAATCGGATCATTTGGTAGGAAACTATGATGTTTTATGA

Upstream 100 bases:

>100_bases
ATTGGATAATTCAGGATAAATTACCAGTTCGTTTTCAACTACAATTACATAAAATTTTATGGAATGATGCACCTGGTCAT
TGACCTCAAGGAGACTAACT

Downstream 100 bases:

>100_bases
TTTTGAAACCACCACTTTCGGCAAGTGGATTTTAGCAGGTGAACATGCGGTAGTAAGGGGGCATGAAGCTTTAGTATTTC
CTATTAAGGAAAGGCAATTA

Product: hypothetical protein

Products: NA

Alternate protein names: Mevalonate Diphosphate Decarboxylase; GHMP Kinase; Mevalonate Pyrophosphate Decarboxylase; Phosphomevalonate Kinase; Ghmp Kinase

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MHWFAQAPANIALIKYMGKKDENSNLPDNSSLSYTLSNLLSSVKLERLPTKKDIWEPLTIPGAPEFNLSVEAQKRFIDHL
VRLKEYFGYVGGFLIQSSNNFPHSSGLASSASSFAALTKCASIALSELTQKPLPSIDEQAQWSRLGSGSSCRSFYAPWAL
WTGDKVSAIDLPYKDLLHQVIVISSQEKEIPSRVAHKLVKTSPFYETRSERAEANLKLLLNAFENKDWTSIYQICWHEFL
DMHQLFKTCEKPFSYITDNTLHILSVIEKFWNEKGDGPVVTMDAGPNVHLLYRSDQTDLARQFKSDHLVGNYDVL

Sequences:

>Translated_315_residues
MHWFAQAPANIALIKYMGKKDENSNLPDNSSLSYTLSNLLSSVKLERLPTKKDIWEPLTIPGAPEFNLSVEAQKRFIDHL
VRLKEYFGYVGGFLIQSSNNFPHSSGLASSASSFAALTKCASIALSELTQKPLPSIDEQAQWSRLGSGSSCRSFYAPWAL
WTGDKVSAIDLPYKDLLHQVIVISSQEKEIPSRVAHKLVKTSPFYETRSERAEANLKLLLNAFENKDWTSIYQICWHEFL
DMHQLFKTCEKPFSYITDNTLHILSVIEKFWNEKGDGPVVTMDAGPNVHLLYRSDQTDLARQFKSDHLVGNYDVL
>Mature_315_residues
MHWFAQAPANIALIKYMGKKDENSNLPDNSSLSYTLSNLLSSVKLERLPTKKDIWEPLTIPGAPEFNLSVEAQKRFIDHL
VRLKEYFGYVGGFLIQSSNNFPHSSGLASSASSFAALTKCASIALSELTQKPLPSIDEQAQWSRLGSGSSCRSFYAPWAL
WTGDKVSAIDLPYKDLLHQVIVISSQEKEIPSRVAHKLVKTSPFYETRSERAEANLKLLLNAFENKDWTSIYQICWHEFL
DMHQLFKTCEKPFSYITDNTLHILSVIEKFWNEKGDGPVVTMDAGPNVHLLYRSDQTDLARQFKSDHLVGNYDVL

Specific function: Unknown

COG id: COG3407

COG function: function code I; Mevalonate pyrophosphate decarboxylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI4505289, Length=320, Percent_Identity=29.375, Blast_Score=79, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6324371, Length=317, Percent_Identity=29.9684542586751, Blast_Score=85, Evalue=2e-17,
Organism=Drosophila melanogaster, GI28571205, Length=307, Percent_Identity=29.6416938110749, Blast_Score=71, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 35651; Mature: 35651

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHWFAQAPANIALIKYMGKKDENSNLPDNSSLSYTLSNLLSSVKLERLPTKKDIWEPLTI
CCCCCCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHCCCCCCC
PGAPEFNLSVEAQKRFIDHLVRLKEYFGYVGGFLIQSSNNFPHSSGLASSASSFAALTKC
CCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCHHHHHHHHHHHHH
ASIALSELTQKPLPSIDEQAQWSRLGSGSSCRSFYAPWALWTGDKVSAIDLPYKDLLHQV
HHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCHHHHCCEEEECCCCCEEECCCHHHHHHHH
IVISSQEKEIPSRVAHKLVKTSPFYETRSERAEANLKLLLNAFENKDWTSIYQICWHEFL
HHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
DMHQLFKTCEKPFSYITDNTLHILSVIEKFWNEKGDGPVVTMDAGPNVHLLYRSDQTDLA
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCEEEEEECCHHHHH
RQFKSDHLVGNYDVL
HHHHCCCCCCCCCCC
>Mature Secondary Structure
MHWFAQAPANIALIKYMGKKDENSNLPDNSSLSYTLSNLLSSVKLERLPTKKDIWEPLTI
CCCCCCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHCCCCCCC
PGAPEFNLSVEAQKRFIDHLVRLKEYFGYVGGFLIQSSNNFPHSSGLASSASSFAALTKC
CCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCHHHHHHHHHHHHH
ASIALSELTQKPLPSIDEQAQWSRLGSGSSCRSFYAPWALWTGDKVSAIDLPYKDLLHQV
HHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCHHHHCCEEEECCCCCEEECCCHHHHHHHH
IVISSQEKEIPSRVAHKLVKTSPFYETRSERAEANLKLLLNAFENKDWTSIYQICWHEFL
HHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
DMHQLFKTCEKPFSYITDNTLHILSVIEKFWNEKGDGPVVTMDAGPNVHLLYRSDQTDLA
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCEEEEEECCHHHHH
RQFKSDHLVGNYDVL
HHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA