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The map label for this gene is carA [H]

Identifier: 54294921

GI number: 54294921

Start: 2241042

End: 2242154

Strand: Reverse

Name: carA [H]

Synonym: lpl2000

Alternate gene names: 54294921

Gene position: 2242154-2241042 (Counterclockwise)

Preceding gene: 54294922

Following gene: 54294920

Centisome position: 67.02

GC content: 40.88

Gene sequence:

>1113_bases
ATGATTAATAAATCAGCAATTTTAGCTTTAGCTGATGGCACTGTTTATGAGGGCCTGTCAGTAGGGGCCATTGGTGAGTC
TGTTGGTGAGTTGGTTTTTAACACGTCAATGACTGGCTATCAGGAAATGCTTACTGATCCTTCGTATGCCAGACAAATAA
TTACCTTAACTACTGCTCATGTGGGAAATACGGGTTGTAACATGGAGGACATGGAGTCCACAAAAGTCTGGGCAGCCGGC
TTGGTTATGAGAAACTGCACTGCTGTTCCAAGTAACTTCAGAGCTGAACAATCCTTCCCTGACTGGTTAAGTAAAAATGG
AGTAGTTGCCATTTCTGGCATTGATACGCGCGCGCTTACATTGAAATTGCGTGAGAAGGGCTCTATCGGAGCTTGTATTA
GCACCAATGTGGAGAAACCTGAAATTGCTGTGGCAAAGGCTAAATCCTTTGCAGGGCTTCAGGGTGCGGATTTGGCTTTA
GAGGTTACAAGGCAAACGATAGAGCGTTGGCATGAAGGTCGGGGAATGTGGAGTCTAGACAAACAGCCTCAACAGCTTCA
TGTTGTTGCCTATGATTTTGGTGTGAAACATAATATTTTACGTATCTTACATGACAAGGGATGCCATATTACTATAGTTC
CTGCTAAAACTTCAGCAGAAGAGGTTTTAGCCATGAATCCTAATGGTGTCTTTTTATCCAATGGACCGGGTGATCCCCAA
GCATGCGATTATGCCATCAAAGCAACACAGGTGTTTTTAGACAATAATATTCCTTTATTTGGTATATGCCTTGGGTTTCA
GATTTTGGCTTTGGCATGTGGTGGTATTACTAAAAAAATGAAATTTGGACATCATGGTTCCAATCATCCTGTAGTTGAAA
CAACTGGTAAAAAAGGTGTTTTTATAACAAGTCAAAATCATGGTTTTGCTGTAGATGAGGATTCATTGCCCGATTGCCTG
GAAGTTACACATCGTTCATTATTTGATAACAGTTTACAGGGAATAAGGCACAAAACAAAACCTGCATTTGGTTTTCAAGG
CCATCCAGAAGCAAGCCCTGGGCCACATGATATAGATATTTTATTTAATGAATTTGTAAATCTGATGAAATAA

Upstream 100 bases:

>100_bases
TTTTGACTTAATTAAGTTACAATTGGAAGATTTGTCGTTTTCAGCATGGATGCCTATTTTACGCTGGATAAGCATACTTT
GAACATAATTGAGTATATTC

Downstream 100 bases:

>100_bases
ATTTTTAGCTTCAGAATTATTATTTTGGCAAGAGTGGCTTGTTTTAAGCTTGCTTACAATGATTGTAATACCCCTAAATG
CTATCCATGGCTATTAAAGA

Product: carbamoyl phosphate synthase small subunit

Products: NA

Alternate protein names: Carbamoyl-phosphate synthetase glutamine chain [H]

Number of amino acids: Translated: 370; Mature: 370

Protein sequence:

>370_residues
MINKSAILALADGTVYEGLSVGAIGESVGELVFNTSMTGYQEMLTDPSYARQIITLTTAHVGNTGCNMEDMESTKVWAAG
LVMRNCTAVPSNFRAEQSFPDWLSKNGVVAISGIDTRALTLKLREKGSIGACISTNVEKPEIAVAKAKSFAGLQGADLAL
EVTRQTIERWHEGRGMWSLDKQPQQLHVVAYDFGVKHNILRILHDKGCHITIVPAKTSAEEVLAMNPNGVFLSNGPGDPQ
ACDYAIKATQVFLDNNIPLFGICLGFQILALACGGITKKMKFGHHGSNHPVVETTGKKGVFITSQNHGFAVDEDSLPDCL
EVTHRSLFDNSLQGIRHKTKPAFGFQGHPEASPGPHDIDILFNEFVNLMK

Sequences:

>Translated_370_residues
MINKSAILALADGTVYEGLSVGAIGESVGELVFNTSMTGYQEMLTDPSYARQIITLTTAHVGNTGCNMEDMESTKVWAAG
LVMRNCTAVPSNFRAEQSFPDWLSKNGVVAISGIDTRALTLKLREKGSIGACISTNVEKPEIAVAKAKSFAGLQGADLAL
EVTRQTIERWHEGRGMWSLDKQPQQLHVVAYDFGVKHNILRILHDKGCHITIVPAKTSAEEVLAMNPNGVFLSNGPGDPQ
ACDYAIKATQVFLDNNIPLFGICLGFQILALACGGITKKMKFGHHGSNHPVVETTGKKGVFITSQNHGFAVDEDSLPDCL
EVTHRSLFDNSLQGIRHKTKPAFGFQGHPEASPGPHDIDILFNEFVNLMK
>Mature_370_residues
MINKSAILALADGTVYEGLSVGAIGESVGELVFNTSMTGYQEMLTDPSYARQIITLTTAHVGNTGCNMEDMESTKVWAAG
LVMRNCTAVPSNFRAEQSFPDWLSKNGVVAISGIDTRALTLKLREKGSIGACISTNVEKPEIAVAKAKSFAGLQGADLAL
EVTRQTIERWHEGRGMWSLDKQPQQLHVVAYDFGVKHNILRILHDKGCHITIVPAKTSAEEVLAMNPNGVFLSNGPGDPQ
ACDYAIKATQVFLDNNIPLFGICLGFQILALACGGITKKMKFGHHGSNHPVVETTGKKGVFITSQNHGFAVDEDSLPDCL
EVTHRSLFDNSLQGIRHKTKPAFGFQGHPEASPGPHDIDILFNEFVNLMK

Specific function: Arginine biosynthesis. Pyrimidine biosynthesis; first step. [C]

COG id: COG0505

COG function: function code EF; Carbamoylphosphate synthase small subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Homo sapiens, GI18105007, Length=376, Percent_Identity=37.2340425531915, Blast_Score=232, Evalue=5e-61,
Organism=Homo sapiens, GI169790915, Length=379, Percent_Identity=32.9815303430079, Blast_Score=197, Evalue=1e-50,
Organism=Homo sapiens, GI21361331, Length=379, Percent_Identity=32.9815303430079, Blast_Score=197, Evalue=2e-50,
Organism=Escherichia coli, GI1786215, Length=377, Percent_Identity=58.3554376657825, Blast_Score=432, Evalue=1e-122,
Organism=Escherichia coli, GI1789760, Length=138, Percent_Identity=30.4347826086957, Blast_Score=66, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI193204318, Length=379, Percent_Identity=35.6200527704486, Blast_Score=218, Evalue=5e-57,
Organism=Saccharomyces cerevisiae, GI6322331, Length=394, Percent_Identity=34.010152284264, Blast_Score=214, Evalue=2e-56,
Organism=Saccharomyces cerevisiae, GI6324878, Length=378, Percent_Identity=37.3015873015873, Blast_Score=213, Evalue=3e-56,
Organism=Saccharomyces cerevisiae, GI6322638, Length=178, Percent_Identity=29.2134831460674, Blast_Score=70, Evalue=8e-13,
Organism=Drosophila melanogaster, GI45555749, Length=386, Percent_Identity=37.3056994818653, Blast_Score=213, Evalue=2e-55,
Organism=Drosophila melanogaster, GI24642586, Length=386, Percent_Identity=37.3056994818653, Blast_Score=213, Evalue=2e-55,

Paralogues:

None

Copy number: 620 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2599 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR006274
- InterPro:   IPR002474
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991 [H]

Pfam domain/function: PF00988 CPSase_sm_chain; PF00117 GATase [H]

EC number: =6.3.5.5 [H]

Molecular weight: Translated: 40061; Mature: 40061

Theoretical pI: Translated: 6.62; Mature: 6.62

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINKSAILALADGTVYEGLSVGAIGESVGELVFNTSMTGYQEMLTDPSYARQIITLTTAH
CCCCCEEEEEECCCCCCCEEECHHHHHHHHHHHCCCCCCHHHHHCCHHHHHEEEEEEEEE
VGNTGCNMEDMESTKVWAAGLVMRNCTAVPSNFRAEQSFPDWLSKNGVVAISGIDTRALT
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHCCCCEEEEECCCCEEEE
LKLREKGSIGACISTNVEKPEIAVAKAKSFAGLQGADLALEVTRQTIERWHEGRGMWSLD
EEEECCCCCCEEEECCCCCCCEEEEHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCC
KQPQQLHVVAYDFGVKHNILRILHDKGCHITIVPAKTSAEEVLAMNPNGVFLSNGPGDPQ
CCCCEEEEEEEECCCHHHHHHHHHCCCCEEEEEECCCCCCCEEEECCCEEEECCCCCCHH
ACDYAIKATQVFLDNNIPLFGICLGFQILALACGGITKKMKFGHHGSNHPVVETTGKKGV
HHHHHEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCEEEECCCCEE
FITSQNHGFAVDEDSLPDCLEVTHRSLFDNSLQGIRHKTKPAFGFQGHPEASPGPHDIDI
EEEECCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHH
LFNEFVNLMK
HHHHHHHHCC
>Mature Secondary Structure
MINKSAILALADGTVYEGLSVGAIGESVGELVFNTSMTGYQEMLTDPSYARQIITLTTAH
CCCCCEEEEEECCCCCCCEEECHHHHHHHHHHHCCCCCCHHHHHCCHHHHHEEEEEEEEE
VGNTGCNMEDMESTKVWAAGLVMRNCTAVPSNFRAEQSFPDWLSKNGVVAISGIDTRALT
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHCCCCEEEEECCCCEEEE
LKLREKGSIGACISTNVEKPEIAVAKAKSFAGLQGADLALEVTRQTIERWHEGRGMWSLD
EEEECCCCCCEEEECCCCCCCEEEEHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCC
KQPQQLHVVAYDFGVKHNILRILHDKGCHITIVPAKTSAEEVLAMNPNGVFLSNGPGDPQ
CCCCEEEEEEEECCCHHHHHHHHHCCCCEEEEEECCCCCCCEEEECCCEEEECCCCCCHH
ACDYAIKATQVFLDNNIPLFGICLGFQILALACGGITKKMKFGHHGSNHPVVETTGKKGV
HHHHHEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCEEEECCCCEE
FITSQNHGFAVDEDSLPDCLEVTHRSLFDNSLQGIRHKTKPAFGFQGHPEASPGPHDIDI
EEEECCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHH
LFNEFVNLMK
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA