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The map label for this gene is uup [H]

Identifier: 54294903

GI number: 54294903

Start: 2222502

End: 2224355

Strand: Reverse

Name: uup [H]

Synonym: lpl1982

Alternate gene names: 54294903

Gene position: 2224355-2222502 (Counterclockwise)

Preceding gene: 54294904

Following gene: 54294902

Centisome position: 66.48

GC content: 39.86

Gene sequence:

>1854_bases
ATGAGTATAGTTTCTCTTAACGGTGCCTCTTTAATCTTGGCTGGCAATTGTATTCTGGACCGTGCAGATTTACAGATTCA
GCCACAGGATAGAATTGCTCTTGTTGGACGCAATGGCGCTGGAAAATCAACATTGCTGAAAATACTACAAGGGGAGTTGG
TGCTTGATAGTGGACAAATTCAACGCTCATCCGGTTTGCGTATTTCTGGTTTAGTGCAGGAAGTCCCAGGTGCTGAGGGA
GAGTCAGTGTACCATTTTCTTGTTAAAAGCTTAGGTGAAACAGGGGAAGTATTGTCCCAGTTTCATGAGTTTACGAAACA
AGGAGATATGGACAAATTGGCCAGGTGTCAGCAACGAATGGACAACTTGAATGCATGGCATTTATTACCTGAAATTGAAA
CGATGGCAAGCCGATTGGGAATAGATATTCATGAGCAGATGTCTAATCTCTCTGGTGGTATGAAACGACGCGTATTATTA
GGTGCGGCACTGCTTGCCAAACCTGATTTATTGTTACTGGATGAACCTACCAACCACTTGGATGTCGAAGCAATTGAATG
GTTAGAGAATTATTTAAAATCCTTTTCTGGTGCTGTAATGGTAGTAACTCACGACAGGGAATTCTTAAGCCAGATAGCAA
CAAGCATCCTTGAAATCGATCGTGGAAAATTGTATCTACACCATTGCAATTATGAAGCTTACCTTGACAGGCGTGAATCG
ATAAGGCTTAGCGAACAAAAACAAAATGATTTGTTTGACAAACGGCTTGCAGAAGAAGAGGCCTGGATACGTACAGGTAT
CAAGGCAAGACGCACACGTAATGAGGGCAGAGTCAGGGCCTTAAAGGCAATGAGAGAGCAGTACAAAGCACGTCGTAATC
AGTTAGGAACAGTGAAATCCTTAAATTTGGATGTAAGCCGTTCTGGTGCTCTTGTAGTAGAAGCAAACAAAGTGAGTTAT
GCAATTAATGACAAGCCCATTATAAAAGATTTTTCTTTATTAATGACAAGAGGAGACAAGCTTGGGATTATCGGCCCCAA
TGGTTGTGGCAAAACCACTTTAGTTCGATTACTTCTGGGAGAAATTAAGCCTGATGCTGGAACTATAAAATTAGGGACAG
GGCTTCAGGTAGCCTATTTTGATCAGTTACGCCGACATTTGCTTGAAGATCAAACAGTCATGTTTAATGTGGGGGAAGGG
GCTGATTATGTAACAATTAATGGTAAGCAAAAACATGTTGCCAGTTATTTGAAAGAGTTTTTATTTTCCTCTGATCGATT
TAATCAGCCAGTATCTTCCTTGTCTGGAGGGGAGAGAAACAGATTATTACTGGCAAAACTTTTTGCCAAACCGGTTAATT
TACTCGTAATGGATGAACCAACTAATGATTTGGATATAGAAACTCTGGAACTTCTTGAAGCTGTATTAGCTGATTATCCT
GGTACTTTAATATTAATCAGTCATGATAGAGCGTTTATTAATCAAGTGGTAACCAGTGTGTTGGTTTATGAAGAAAATGG
TAAGTTTAATGAATTTGTTGGTGGTTATGACGATTATAAAAAACATCAATTAACACGAAATGAGCAGCAAACGAAATCTC
CAGTTTCAAAACGGAGCAGCCCAGAGAAAGCCAAAAATTTATCTTTTAATGAACAACGTGAGTTATCGAAGTTGCCGCAA
CAGATTGAAGCCGTAGAGAAAAAAATTGAAGCACTGCATTCGCAAATGGCCTCACCTGAATTTTATCAGCAAGATGCCAA
GCTTATTTCAGAGGTAACTCAGCTGTTAGCCAAGGAAGAGGCATTGTTAAATCAATATTTTGCTCGATGGGAAGAGCTGG
AAGAGAAAAAATAA

Upstream 100 bases:

>100_bases
GATTCAGCAGGGCAAACAATTGATATTAAAAAGACAATGAACTGACTGTGTGTTTTCAATAAAATGAGATCAAACAGATT
TATTTAAATAGAGAGTTTTG

Downstream 100 bases:

>100_bases
TAAAGTATTTGGTTAATTGATAAGTTTAAATGAAAAACAATAGAAAGATATCTTTAAATAAAATTAAAAATAGGATTTAA
AATGCTTTTAACCTTGGCTT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 617; Mature: 616

Protein sequence:

>617_residues
MSIVSLNGASLILAGNCILDRADLQIQPQDRIALVGRNGAGKSTLLKILQGELVLDSGQIQRSSGLRISGLVQEVPGAEG
ESVYHFLVKSLGETGEVLSQFHEFTKQGDMDKLARCQQRMDNLNAWHLLPEIETMASRLGIDIHEQMSNLSGGMKRRVLL
GAALLAKPDLLLLDEPTNHLDVEAIEWLENYLKSFSGAVMVVTHDREFLSQIATSILEIDRGKLYLHHCNYEAYLDRRES
IRLSEQKQNDLFDKRLAEEEAWIRTGIKARRTRNEGRVRALKAMREQYKARRNQLGTVKSLNLDVSRSGALVVEANKVSY
AINDKPIIKDFSLLMTRGDKLGIIGPNGCGKTTLVRLLLGEIKPDAGTIKLGTGLQVAYFDQLRRHLLEDQTVMFNVGEG
ADYVTINGKQKHVASYLKEFLFSSDRFNQPVSSLSGGERNRLLLAKLFAKPVNLLVMDEPTNDLDIETLELLEAVLADYP
GTLILISHDRAFINQVVTSVLVYEENGKFNEFVGGYDDYKKHQLTRNEQQTKSPVSKRSSPEKAKNLSFNEQRELSKLPQ
QIEAVEKKIEALHSQMASPEFYQQDAKLISEVTQLLAKEEALLNQYFARWEELEEKK

Sequences:

>Translated_617_residues
MSIVSLNGASLILAGNCILDRADLQIQPQDRIALVGRNGAGKSTLLKILQGELVLDSGQIQRSSGLRISGLVQEVPGAEG
ESVYHFLVKSLGETGEVLSQFHEFTKQGDMDKLARCQQRMDNLNAWHLLPEIETMASRLGIDIHEQMSNLSGGMKRRVLL
GAALLAKPDLLLLDEPTNHLDVEAIEWLENYLKSFSGAVMVVTHDREFLSQIATSILEIDRGKLYLHHCNYEAYLDRRES
IRLSEQKQNDLFDKRLAEEEAWIRTGIKARRTRNEGRVRALKAMREQYKARRNQLGTVKSLNLDVSRSGALVVEANKVSY
AINDKPIIKDFSLLMTRGDKLGIIGPNGCGKTTLVRLLLGEIKPDAGTIKLGTGLQVAYFDQLRRHLLEDQTVMFNVGEG
ADYVTINGKQKHVASYLKEFLFSSDRFNQPVSSLSGGERNRLLLAKLFAKPVNLLVMDEPTNDLDIETLELLEAVLADYP
GTLILISHDRAFINQVVTSVLVYEENGKFNEFVGGYDDYKKHQLTRNEQQTKSPVSKRSSPEKAKNLSFNEQRELSKLPQ
QIEAVEKKIEALHSQMASPEFYQQDAKLISEVTQLLAKEEALLNQYFARWEELEEKK
>Mature_616_residues
SIVSLNGASLILAGNCILDRADLQIQPQDRIALVGRNGAGKSTLLKILQGELVLDSGQIQRSSGLRISGLVQEVPGAEGE
SVYHFLVKSLGETGEVLSQFHEFTKQGDMDKLARCQQRMDNLNAWHLLPEIETMASRLGIDIHEQMSNLSGGMKRRVLLG
AALLAKPDLLLLDEPTNHLDVEAIEWLENYLKSFSGAVMVVTHDREFLSQIATSILEIDRGKLYLHHCNYEAYLDRRESI
RLSEQKQNDLFDKRLAEEEAWIRTGIKARRTRNEGRVRALKAMREQYKARRNQLGTVKSLNLDVSRSGALVVEANKVSYA
INDKPIIKDFSLLMTRGDKLGIIGPNGCGKTTLVRLLLGEIKPDAGTIKLGTGLQVAYFDQLRRHLLEDQTVMFNVGEGA
DYVTINGKQKHVASYLKEFLFSSDRFNQPVSSLSGGERNRLLLAKLFAKPVNLLVMDEPTNDLDIETLELLEAVLADYPG
TLILISHDRAFINQVVTSVLVYEENGKFNEFVGGYDDYKKHQLTRNEQQTKSPVSKRSSPEKAKNLSFNEQRELSKLPQQ
IEAVEKKIEALHSQMASPEFYQQDAKLISEVTQLLAKEEALLNQYFARWEELEEKK

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=529, Percent_Identity=29.1115311909263, Blast_Score=201, Evalue=3e-51,
Organism=Homo sapiens, GI10947135, Length=553, Percent_Identity=27.4864376130199, Blast_Score=170, Evalue=4e-42,
Organism=Homo sapiens, GI69354671, Length=553, Percent_Identity=27.4864376130199, Blast_Score=170, Evalue=4e-42,
Organism=Homo sapiens, GI27881506, Length=535, Percent_Identity=26.5420560747664, Blast_Score=166, Evalue=8e-41,
Organism=Homo sapiens, GI10947137, Length=535, Percent_Identity=26.5420560747664, Blast_Score=165, Evalue=1e-40,
Organism=Homo sapiens, GI42741659, Length=210, Percent_Identity=25.7142857142857, Blast_Score=67, Evalue=6e-11,
Organism=Escherichia coli, GI1787182, Length=640, Percent_Identity=46.875, Blast_Score=547, Evalue=1e-157,
Organism=Escherichia coli, GI2367384, Length=534, Percent_Identity=36.7041198501873, Blast_Score=315, Evalue=4e-87,
Organism=Escherichia coli, GI1789751, Length=587, Percent_Identity=29.3015332197615, Blast_Score=260, Evalue=1e-70,
Organism=Escherichia coli, GI1787041, Length=506, Percent_Identity=32.0158102766798, Blast_Score=250, Evalue=2e-67,
Organism=Escherichia coli, GI1788506, Length=532, Percent_Identity=25, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1788165, Length=199, Percent_Identity=30.1507537688442, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1787758, Length=186, Percent_Identity=27.4193548387097, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI1788225, Length=224, Percent_Identity=27.6785714285714, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1787029, Length=240, Percent_Identity=27.0833333333333, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI87081791, Length=242, Percent_Identity=26.8595041322314, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI87081782, Length=184, Percent_Identity=29.8913043478261, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1787164, Length=201, Percent_Identity=27.363184079602, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1786563, Length=176, Percent_Identity=30.1136363636364, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1789963, Length=223, Percent_Identity=29.5964125560538, Blast_Score=66, Evalue=7e-12,
Organism=Escherichia coli, GI1786319, Length=231, Percent_Identity=28.1385281385281, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1786872, Length=213, Percent_Identity=26.2910798122066, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1787105, Length=192, Percent_Identity=31.7708333333333, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI145693107, Length=219, Percent_Identity=27.3972602739726, Blast_Score=64, Evalue=4e-11,
Organism=Escherichia coli, GI1787370, Length=283, Percent_Identity=24.0282685512367, Blast_Score=62, Evalue=1e-10,
Organism=Caenorhabditis elegans, GI17559834, Length=545, Percent_Identity=26.0550458715596, Blast_Score=187, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI17555318, Length=543, Percent_Identity=26.7034990791897, Blast_Score=178, Evalue=7e-45,
Organism=Caenorhabditis elegans, GI17553372, Length=554, Percent_Identity=29.2418772563177, Blast_Score=169, Evalue=4e-42,
Organism=Saccharomyces cerevisiae, GI6320874, Length=553, Percent_Identity=25.6781193490054, Blast_Score=171, Evalue=4e-43,
Organism=Saccharomyces cerevisiae, GI6321121, Length=550, Percent_Identity=26.7272727272727, Blast_Score=166, Evalue=7e-42,
Organism=Saccharomyces cerevisiae, GI6325030, Length=378, Percent_Identity=27.7777777777778, Blast_Score=118, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6323278, Length=376, Percent_Identity=24.7340425531915, Blast_Score=110, Evalue=5e-25,
Organism=Saccharomyces cerevisiae, GI6324314, Length=378, Percent_Identity=25.3968253968254, Blast_Score=106, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6324985, Length=176, Percent_Identity=28.4090909090909, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24666836, Length=534, Percent_Identity=29.7752808988764, Blast_Score=214, Evalue=1e-55,
Organism=Drosophila melanogaster, GI24642252, Length=554, Percent_Identity=27.9783393501805, Blast_Score=202, Evalue=6e-52,
Organism=Drosophila melanogaster, GI18859989, Length=554, Percent_Identity=27.9783393501805, Blast_Score=202, Evalue=6e-52,
Organism=Drosophila melanogaster, GI24641342, Length=552, Percent_Identity=29.3478260869565, Blast_Score=196, Evalue=4e-50,
Organism=Drosophila melanogaster, GI281363262, Length=183, Percent_Identity=26.2295081967213, Blast_Score=67, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24653245, Length=183, Percent_Identity=26.2295081967213, Blast_Score=67, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 69461; Mature: 69330

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIVSLNGASLILAGNCILDRADLQIQPQDRIALVGRNGAGKSTLLKILQGELVLDSGQI
CEEEEECCCEEEEECCEEEECCCCEECCCCCEEEEECCCCCHHHHHHHHHCCEEECCCCC
QRSSGLRISGLVQEVPGAEGESVYHFLVKSLGETGEVLSQFHEFTKQGDMDKLARCQQRM
CCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHH
DNLNAWHLLPEIETMASRLGIDIHEQMSNLSGGMKRRVLLGAALLAKPDLLLLDEPTNHL
CCCCCEEECHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEECCCCCC
DVEAIEWLENYLKSFSGAVMVVTHDREFLSQIATSILEIDRGKLYLHHCNYEAYLDRRES
CHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHCCCEEEEEECCHHHHHCHHHH
IRLSEQKQNDLFDKRLAEEEAWIRTGIKARRTRNEGRVRALKAMREQYKARRNQLGTVKS
CCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEE
LNLDVSRSGALVVEANKVSYAINDKPIIKDFSLLMTRGDKLGIIGPNGCGKTTLVRLLLG
ECEEECCCCEEEEEECCEEEEECCCCHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHH
EIKPDAGTIKLGTGLQVAYFDQLRRHLLEDQTVMFNVGEGADYVTINGKQKHVASYLKEF
HCCCCCCEEEECCCCCHHHHHHHHHHHHCCCEEEEEECCCCCEEEECCCHHHHHHHHHHH
LFSSDRFNQPVSSLSGGERNRLLLAKLFAKPVNLLVMDEPTNDLDIETLELLEAVLADYP
HHCCCCCCCCHHHCCCCCCCHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHCCC
GTLILISHDRAFINQVVTSVLVYEENGKFNEFVGGYDDYKKHQLTRNEQQTKSPVSKRSS
CEEEEEECCHHHHHHHHHHHEEECCCCCHHHHCCCCHHHHHHHHCCCHHHHHCCHHHCCC
PEKAKNLSFNEQRELSKLPQQIEAVEKKIEALHSQMASPEFYQQDAKLISEVTQLLAKEE
CHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
ALLNQYFARWEELEEKK
HHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SIVSLNGASLILAGNCILDRADLQIQPQDRIALVGRNGAGKSTLLKILQGELVLDSGQI
EEEEECCCEEEEECCEEEECCCCEECCCCCEEEEECCCCCHHHHHHHHHCCEEECCCCC
QRSSGLRISGLVQEVPGAEGESVYHFLVKSLGETGEVLSQFHEFTKQGDMDKLARCQQRM
CCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHH
DNLNAWHLLPEIETMASRLGIDIHEQMSNLSGGMKRRVLLGAALLAKPDLLLLDEPTNHL
CCCCCEEECHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEECCCCCC
DVEAIEWLENYLKSFSGAVMVVTHDREFLSQIATSILEIDRGKLYLHHCNYEAYLDRRES
CHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHCCCEEEEEECCHHHHHCHHHH
IRLSEQKQNDLFDKRLAEEEAWIRTGIKARRTRNEGRVRALKAMREQYKARRNQLGTVKS
CCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEE
LNLDVSRSGALVVEANKVSYAINDKPIIKDFSLLMTRGDKLGIIGPNGCGKTTLVRLLLG
ECEEECCCCEEEEEECCEEEEECCCCHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHH
EIKPDAGTIKLGTGLQVAYFDQLRRHLLEDQTVMFNVGEGADYVTINGKQKHVASYLKEF
HCCCCCCEEEECCCCCHHHHHHHHHHHHCCCEEEEEECCCCCEEEECCCHHHHHHHHHHH
LFSSDRFNQPVSSLSGGERNRLLLAKLFAKPVNLLVMDEPTNDLDIETLELLEAVLADYP
HHCCCCCCCCHHHCCCCCCCHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHCCC
GTLILISHDRAFINQVVTSVLVYEENGKFNEFVGGYDDYKKHQLTRNEQQTKSPVSKRSS
CEEEEEECCHHHHHHHHHHHEEECCCCCHHHHCCCCHHHHHHHHCCCHHHHHCCHHHCCC
PEKAKNLSFNEQRELSKLPQQIEAVEKKIEALHSQMASPEFYQQDAKLISEVTQLLAKEE
CHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
ALLNQYFARWEELEEKK
HHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Endonuclease; Excision [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 9139905; 7751275 [H]