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The map label for this gene is yfcG [H]

Identifier: 54294869

GI number: 54294869

Start: 2186659

End: 2187282

Strand: Reverse

Name: yfcG [H]

Synonym: lpl1948

Alternate gene names: 54294869

Gene position: 2187282-2186659 (Counterclockwise)

Preceding gene: 54294870

Following gene: 54294862

Centisome position: 65.38

GC content: 39.1

Gene sequence:

>624_bases
ATGTATACACTTTATTCATTCGGGACGCCCAACGGATTTAAACCCACTATTATGTTGGAAGAGTTGGCACTGCCTTACAC
CATAAAACTGATTGATATTACTCAGGGTGAACAATTTGATCCTGATTTTTTAAAAATTTCACCAAACAATAAGATACCGG
TTTTGCATGATCAAACCAATGATTTTTACCTAATGGAAAGTGTTGCTATTTTGCAATATTTGGCTGAAAAACATAGACAG
TTTTTGCCTGAAACGACAAAGGAGAAATATGCCATTATCCAATGGTGTTATTTCCAGGCAGCACACATAGGCCCTATGTT
AGGGCAATTTGGTCATTTTCATCGTTATGCTCAAGAGCAAGTACCCTATGCCATGAAGCGATATGCTGATGAATCCATGC
GACTTCTAGGGGTTATGGAAAAGCAACTGGCCAAAACGTCATTCATTGGCGGATCAAATTATACTATTGCCGATATGGCT
ATCTGGCCCTGGATTTGGTGTTTTCAATTCGTATATGAACAGACTATTGATGAGAAACTGTTTCCCTGTTTAATGTCCTG
GTATCAACGAGTTAGTGAAAGACCTGCCGTTAAAGAGACTTTAGCCTCTTATGGGCGGCTATAA

Upstream 100 bases:

>100_bases
TTTGTCCTTATTCCAATGCAATACGTGGTAATGTTGAAGTGAAATTGAGTGTTAGTGTCAAGTGATAGATAACTTCCATC
AATTAAATAAGGATATCTTA

Downstream 100 bases:

>100_bases
TCATGAATATCCATTAGATAGTTAGTGATGTAGTTGCACTTATCTGATAATTAAAAGCTCCCAATTGCCGTAATGGTGCC
CATTGGGATGCTTTACTTGG

Product: hypothetical protein

Products: NA

Alternate protein names: GST-like protein yfcG [H]

Number of amino acids: Translated: 207; Mature: 207

Protein sequence:

>207_residues
MYTLYSFGTPNGFKPTIMLEELALPYTIKLIDITQGEQFDPDFLKISPNNKIPVLHDQTNDFYLMESVAILQYLAEKHRQ
FLPETTKEKYAIIQWCYFQAAHIGPMLGQFGHFHRYAQEQVPYAMKRYADESMRLLGVMEKQLAKTSFIGGSNYTIADMA
IWPWIWCFQFVYEQTIDEKLFPCLMSWYQRVSERPAVKETLASYGRL

Sequences:

>Translated_207_residues
MYTLYSFGTPNGFKPTIMLEELALPYTIKLIDITQGEQFDPDFLKISPNNKIPVLHDQTNDFYLMESVAILQYLAEKHRQ
FLPETTKEKYAIIQWCYFQAAHIGPMLGQFGHFHRYAQEQVPYAMKRYADESMRLLGVMEKQLAKTSFIGGSNYTIADMA
IWPWIWCFQFVYEQTIDEKLFPCLMSWYQRVSERPAVKETLASYGRL
>Mature_207_residues
MYTLYSFGTPNGFKPTIMLEELALPYTIKLIDITQGEQFDPDFLKISPNNKIPVLHDQTNDFYLMESVAILQYLAEKHRQ
FLPETTKEKYAIIQWCYFQAAHIGPMLGQFGHFHRYAQEQVPYAMKRYADESMRLLGVMEKQLAKTSFIGGSNYTIADMA
IWPWIWCFQFVYEQTIDEKLFPCLMSWYQRVSERPAVKETLASYGRL

Specific function: Has disulfide bond reductase activity (in vitro). Has low hydroperoxidase activity with cumene hydroperoxide. Has very low glutathione-S-transferase activity (in vitro) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GST N-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1788640, Length=206, Percent_Identity=43.6893203883495, Blast_Score=180, Evalue=6e-47,
Organism=Escherichia coli, GI87082195, Length=207, Percent_Identity=42.512077294686, Blast_Score=157, Evalue=5e-40,
Organism=Escherichia coli, GI87081789, Length=209, Percent_Identity=28.7081339712919, Blast_Score=75, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6324100, Length=241, Percent_Identity=29.8755186721992, Blast_Score=100, Evalue=1e-22,
Organism=Drosophila melanogaster, GI28571670, Length=185, Percent_Identity=31.8918918918919, Blast_Score=79, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010987
- InterPro:   IPR004045
- InterPro:   IPR017933
- InterPro:   IPR004046
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00043 GST_C; PF02798 GST_N [H]

EC number: NA

Molecular weight: Translated: 24316; Mature: 24316

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYTLYSFGTPNGFKPTIMLEELALPYTIKLIDITQGEQFDPDFLKISPNNKIPVLHDQTN
CEEEEECCCCCCCCCHHHHHHHCCCEEEEEEEECCCCCCCCCEEEECCCCCCCEEECCCC
DFYLMESVAILQYLAEKHRQFLPETTKEKYAIIQWCYFQAAHIGPMLGQFGHFHRYAQEQ
CCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VPYAMKRYADESMRLLGVMEKQLAKTSFIGGSNYTIADMAIWPWIWCFQFVYEQTIDEKL
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHH
FPCLMSWYQRVSERPAVKETLASYGRL
HHHHHHHHHHHHCCCHHHHHHHHHCCC
>Mature Secondary Structure
MYTLYSFGTPNGFKPTIMLEELALPYTIKLIDITQGEQFDPDFLKISPNNKIPVLHDQTN
CEEEEECCCCCCCCCHHHHHHHCCCEEEEEEEECCCCCCCCCEEEECCCCCCCEEECCCC
DFYLMESVAILQYLAEKHRQFLPETTKEKYAIIQWCYFQAAHIGPMLGQFGHFHRYAQEQ
CCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VPYAMKRYADESMRLLGVMEKQLAKTSFIGGSNYTIADMAIWPWIWCFQFVYEQTIDEKL
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHH
FPCLMSWYQRVSERPAVKETLASYGRL
HHHHHHHHHHHHCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]