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The map label for this gene is yfeW [C]

Identifier: 54294797

GI number: 54294797

Start: 2097055

End: 2098317

Strand: Reverse

Name: yfeW [C]

Synonym: lpl1874

Alternate gene names: 54294797

Gene position: 2098317-2097055 (Counterclockwise)

Preceding gene: 54294798

Following gene: 54294796

Centisome position: 62.72

GC content: 38.16

Gene sequence:

>1263_bases
ATGAAAATAAATAACTTAGTTGGTTTTCTGCTTGCCTTCTGCCTGGCTTCTTTATCTTATAACATCAGCGCAGCTGAATC
TCCTGTTGTATCTCATCATAAAATTCAAAAGGAAATGAGCAAGTACTTCAAGGTTTATCATAACAAAGAAAAATTTACTG
CCATTGCTGTCTCAGTGTTTATTCCTCAAGAGAAAAATAAGGATGCATTGGATGTTGCCACTTTTGTCAAAGGAACTATG
GGATATCCTCCACTGTCTCAGGAAATTACCCCATTGAATTTGTTTGATATTGGAAGTATTACCAAATCATTTACTTCATT
GATTTTGCTTCAATTGCAGACAGAGGGCAAATTGTCACTGGATGACCCTTTGGGTAAATGGCTGCCTCAATACAAAGAGT
GGAAAGATGTAAAATTAAGACAATTATTGAATATGACCAGTGGCATCCCCAATTATTCCGAAGATCCTGAATTTGCAAAA
AAGATGGAGGATAATTTTGCGGCAATCTGGGGCGATGAGGAGTTGTTAGGTTATGCTCATCCAGAAAAGCCAATAGAAAC
CGACAGAGCAAACAGGTATGAGTATTCCAATTCTAATTATATTCTTGCTGGAATGGTTATTGAAAAAGTGACTCAAGATA
CTTTCGAAAATCAGTTAAAACAAAGGATTATTAATACAAACAATGGATTAAACAATTCATTTTATCCTGCAGGACCACAT
GGTCCAGAAGTCGAAAAATCAATCCGGGATAGACGAGTCCATGGTTATTTTTACGATGAGGATAACAAAAAACTAATTGA
TACTATAAGCAATGATTTATCCTGGGCTGGCGCAGCAGGTGCTGTTATCGCAAATACTGAAGACGTCGGTCGTTGGGTGC
AGCTGCTATACCATGGGTTACTGATAGAACCTGCTTTTAGAGACGAGGTTCTATCCGAATTGGAGTCAGTGGTTTCAATA
AAAACAGGGTTACCTATCCCTTCAGTCACAGAAGATGAGCCCTACGGTTTTGGATTGGGAGTTGGTTTTTATTATGATAA
AAATTCCAGGCAGCGTTTTTGGACTTACCAGGGCAGTACTTTAGGTTACAGGGTGATGTATCTGTGGAATCCTTGTAATA
ATGTAACGGTTGTTGTGGCTTTGAATGGGAAAGGTGGCTCAGGCAATGAGAAATCAAAAATGGGCAACCATATCCATGAG
CTTTGTTTGAATATACATAAAGTTATCGTTAAAAACCATCCACACATACAATGTGCAAGCTAA

Upstream 100 bases:

>100_bases
ATTCAACAGAACATCTCCTGTTTTTTTTATTTTATGGATCTATTTGAGTCTATCAGGTTAAAATGGCCAATTTTCTACTT
AACTTGATGTATTTTTCGCC

Downstream 100 bases:

>100_bases
TTTATTATTTATCATTATTGGTTGTTAAGGACTGAATCACATGGCAATCTGTATTAATAAAGAAACAGATCACTTTTTTA
TTTCGATAGGTAAAATCAAT

Product: hypothetical protein

Products: NA

Alternate protein names: DD-carboxypeptidase; DD-peptidase [H]

Number of amino acids: Translated: 420; Mature: 420

Protein sequence:

>420_residues
MKINNLVGFLLAFCLASLSYNISAAESPVVSHHKIQKEMSKYFKVYHNKEKFTAIAVSVFIPQEKNKDALDVATFVKGTM
GYPPLSQEITPLNLFDIGSITKSFTSLILLQLQTEGKLSLDDPLGKWLPQYKEWKDVKLRQLLNMTSGIPNYSEDPEFAK
KMEDNFAAIWGDEELLGYAHPEKPIETDRANRYEYSNSNYILAGMVIEKVTQDTFENQLKQRIINTNNGLNNSFYPAGPH
GPEVEKSIRDRRVHGYFYDEDNKKLIDTISNDLSWAGAAGAVIANTEDVGRWVQLLYHGLLIEPAFRDEVLSELESVVSI
KTGLPIPSVTEDEPYGFGLGVGFYYDKNSRQRFWTYQGSTLGYRVMYLWNPCNNVTVVVALNGKGGSGNEKSKMGNHIHE
LCLNIHKVIVKNHPHIQCAS

Sequences:

>Translated_420_residues
MKINNLVGFLLAFCLASLSYNISAAESPVVSHHKIQKEMSKYFKVYHNKEKFTAIAVSVFIPQEKNKDALDVATFVKGTM
GYPPLSQEITPLNLFDIGSITKSFTSLILLQLQTEGKLSLDDPLGKWLPQYKEWKDVKLRQLLNMTSGIPNYSEDPEFAK
KMEDNFAAIWGDEELLGYAHPEKPIETDRANRYEYSNSNYILAGMVIEKVTQDTFENQLKQRIINTNNGLNNSFYPAGPH
GPEVEKSIRDRRVHGYFYDEDNKKLIDTISNDLSWAGAAGAVIANTEDVGRWVQLLYHGLLIEPAFRDEVLSELESVVSI
KTGLPIPSVTEDEPYGFGLGVGFYYDKNSRQRFWTYQGSTLGYRVMYLWNPCNNVTVVVALNGKGGSGNEKSKMGNHIHE
LCLNIHKVIVKNHPHIQCAS
>Mature_420_residues
MKINNLVGFLLAFCLASLSYNISAAESPVVSHHKIQKEMSKYFKVYHNKEKFTAIAVSVFIPQEKNKDALDVATFVKGTM
GYPPLSQEITPLNLFDIGSITKSFTSLILLQLQTEGKLSLDDPLGKWLPQYKEWKDVKLRQLLNMTSGIPNYSEDPEFAK
KMEDNFAAIWGDEELLGYAHPEKPIETDRANRYEYSNSNYILAGMVIEKVTQDTFENQLKQRIINTNNGLNNSFYPAGPH
GPEVEKSIRDRRVHGYFYDEDNKKLIDTISNDLSWAGAAGAVIANTEDVGRWVQLLYHGLLIEPAFRDEVLSELESVVSI
KTGLPIPSVTEDEPYGFGLGVGFYYDKNSRQRFWTYQGSTLGYRVMYLWNPCNNVTVVVALNGKGGSGNEKSKMGNHIHE
LCLNIHKVIVKNHPHIQCAS

Specific function: Catalyzes distinct carboxypeptidation and transpeptidation reactions during the last stages of wall peptidoglycan synthesis. Mistaking a beta-lactam antibiotic molecule for a normal substrate (i.e., a D-alanyl-D-alanine- terminated peptide), it becomes im

COG id: COG1680

COG function: function code V; Beta-lactamase class C and other penicillin binding proteins

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S12 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001466 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: =3.4.16.4 [H]

Molecular weight: Translated: 47398; Mature: 47398

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKINNLVGFLLAFCLASLSYNISAAESPVVSHHKIQKEMSKYFKVYHNKEKFTAIAVSVF
CCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEE
IPQEKNKDALDVATFVKGTMGYPPLSQEITPLNLFDIGSITKSFTSLILLQLQTEGKLSL
ECCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHEEEEEECCCCCCC
DDPLGKWLPQYKEWKDVKLRQLLNMTSGIPNYSEDPEFAKKMEDNFAAIWGDEELLGYAH
CCHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCEEEEECCHHHHCCCC
PEKPIETDRANRYEYSNSNYILAGMVIEKVTQDTFENQLKQRIINTNNGLNNSFYPAGPH
CCCCCCCCCCCCEEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
GPEVEKSIRDRRVHGYFYDEDNKKLIDTISNDLSWAGAAGAVIANTEDVGRWVQLLYHGL
CCHHHHHHHHCEEEEEEEECCCCHHHHHHHCCCCCCCCCCEEEECCHHHHHHHHHHHHHH
LIEPAFRDEVLSELESVVSIKTGLPIPSVTEDEPYGFGLGVGFYYDKNSRQRFWTYQGST
HCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEEECCCCCCEEEEECCCC
LGYRVMYLWNPCNNVTVVVALNGKGGSGNEKSKMGNHIHELCLNIHKVIVKNHPHIQCAS
CCEEEEEEECCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEECC
>Mature Secondary Structure
MKINNLVGFLLAFCLASLSYNISAAESPVVSHHKIQKEMSKYFKVYHNKEKFTAIAVSVF
CCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEE
IPQEKNKDALDVATFVKGTMGYPPLSQEITPLNLFDIGSITKSFTSLILLQLQTEGKLSL
ECCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHEEEEEECCCCCCC
DDPLGKWLPQYKEWKDVKLRQLLNMTSGIPNYSEDPEFAKKMEDNFAAIWGDEELLGYAH
CCHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCEEEEECCHHHHCCCC
PEKPIETDRANRYEYSNSNYILAGMVIEKVTQDTFENQLKQRIINTNNGLNNSFYPAGPH
CCCCCCCCCCCCEEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
GPEVEKSIRDRRVHGYFYDEDNKKLIDTISNDLSWAGAAGAVIANTEDVGRWVQLLYHGL
CCHHHHHHHHCEEEEEEEECCCCHHHHHHHCCCCCCCCCCEEEECCHHHHHHHHHHHHHH
LIEPAFRDEVLSELESVVSIKTGLPIPSVTEDEPYGFGLGVGFYYDKNSRQRFWTYQGST
HCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEEECCCCCCEEEEECCCC
LGYRVMYLWNPCNNVTVVVALNGKGGSGNEKSKMGNHIHELCLNIHKVIVKNHPHIQCAS
CCEEEEEEECCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3830154; 7925404; 3030739; 2175384; 2386365; 3997832; 7490745 [H]