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The map label for this gene is ppiD [H]

Identifier: 54294744

GI number: 54294744

Start: 2035856

End: 2037730

Strand: Reverse

Name: ppiD [H]

Synonym: lpl1821

Alternate gene names: 54294744

Gene position: 2037730-2035856 (Counterclockwise)

Preceding gene: 54294745

Following gene: 54294740

Centisome position: 60.91

GC content: 35.47

Gene sequence:

>1875_bases
ATGTTGCAGAAGTTAAATGAACACATTCAGGGTGTAGTAGCGTGGTTAGTTATTATATTAATTGCTATTACCTTTACACT
TTTTGGTGTTGATTATTATTTTCAATCTCGACAAATATCCGATGCAAAGGTAATAGTTAATGATAAACCAATTACCATGC
AAGCGTTTGAAACGAACTATAGACGTACTCGTGCCCAGCAAGATTTACCACAGATGACTGCTGCTGATGAAAAAAATCTG
CAAAATCAAGTATTAAATCAAATGATAACGAATGAGGTGAGTATTCAGGCTGCCAGGAAATATGGATTTGAGGTTAGCCC
AGAACAAGCCAATGCGGCCATAGTGCAAATTCCTCAATTCCAGGAGGATGGGCATTTTTCGGCACAACGATATCAACAAG
CTTTGAGTGGAGCTTTGTTTACTCCAGAGACTTTCCAGAAAGAAGTAAGGCAAGGCATGTTGCTTAATCAACAACGTTTT
GCGTTTATGGGAACTTCATTTGCTTTATCAGATGAAATAAAGCGTTTTGTCAGATTGTATATGCAGACCAGGGATTATGA
TTATTTGACGGTACCTTCTGATCGCTTTGAACAACAGGCGAAGATTTCAGAAGATGATATCAAGAGTTATTATAACCAAC
ACCATAAAAAATTTATGACTTCAGAGCAAGTTACATTGGATTATGTGCTTTTGTCTATGCATGATATCAAGTCACAAATA
AAGATATCACCCGACGAAATTAAAAGCTATTATGAAGAAAACAAAAGCAACTACCTAACTCCTGCTCAATGGCGGGTTGC
CCATATTTTATTTGCAGTCCCAGAAAATGCCACCAAGGAAGAACAAGATTCAATTAAGCAAAAAGCCGATGAGGTTTATA
ACGATTTAAAAAAGCATCCAGAACAATTTGATAAATATGTTGCTTCCAAATCTGATGACAAATTATCTATAGCCAATAAG
GGTATTCTTCCCTGGATTACTGGCGGGCAAAATGAATATGACAGAGTGCTTTCCAATTTAACTAGACCAGGGCAAATTTC
TATACCAGTACAAACAAAATATGGTTATGAAATTTTTAAGCTGATTGCTTACAAGCCAGTTACAACTAAATCTTTGCAAG
AAGTTGAAAACATTATAAAAGATCAACTAACCAGTGATATGGCTCAAGCAAAATACGCTCAAGTTTTAGAGCAATTAACA
GACTTAAGTTATCAAACTCCTGATTCACTTGATCCGGTTTTGGATTCATTAAAGCTGAAAATTCAACATACAGAGCCTTT
TTCTCGTTATGGTGGTAAGCAACCTATTACCAAAAATAAGCAGGTTATCCATGCAGCATTCAGCACTGATGTTTTAGAAC
TAGGGAATAATAGCGAGCCTATACAGATTGATAATGACTCTGTAATAGTTTTACGAGTGAAGAAACATATACCTTCAAGA
GAACAAACCTTGGATGAAGTGAGAGATCAGATTAAAAAAGTACTTGCAAAACAGTATGGGGATGCTAAAGCAAAAGAAAT
TGGTAGTAGTTTGCTTCACCCCGTTGAAGATAAGCAACAGCAGGAATTAATCGCTAACAATCAATTCGAATGGCATTCTG
TAGAGAATGCTTCCAGGGATAGTGATAAAGCAAATTCTTTAATTAATGATTTAGCATTTAATTTATTACGTCCAGAAAGC
CGAGACGGAGTAATTTTAGACAACGGCGATTATGTTGTTGTTAAATTAAAACGAATTAATGATGGAAAATTAAGCTCTTT
GGATCAAGAGCAAAGAGATAGCTTGATACAGCAAATAGAAGCTAGCTATGGAATGATGGATTATGATTTATATGTTAATA
ACTTACTTCATCATGCGAAAATAGAAAGGAAATAG

Upstream 100 bases:

>100_bases
ACTCCGCCAGATAAACGCGCTGAAAGGCGCGTTTTTTTTATCAGCTTATGGTAGAATCGGTTTCATCAAGCATTGTTAAT
ATCAAAATGGATCTCGGGAC

Downstream 100 bases:

>100_bases
GACAAGAAAATGGCTGTTCCTCATGAAATTAAGGGATGGCCAGATATCAAGATTTCTTCAGTTTTACCTATAGCTCCCCT
CAGTGAGGCTATTTCAGAGT

Product: hypothetical protein

Products: NA

Alternate protein names: PPIase D; Rotamase D [H]

Number of amino acids: Translated: 624; Mature: 624

Protein sequence:

>624_residues
MLQKLNEHIQGVVAWLVIILIAITFTLFGVDYYFQSRQISDAKVIVNDKPITMQAFETNYRRTRAQQDLPQMTAADEKNL
QNQVLNQMITNEVSIQAARKYGFEVSPEQANAAIVQIPQFQEDGHFSAQRYQQALSGALFTPETFQKEVRQGMLLNQQRF
AFMGTSFALSDEIKRFVRLYMQTRDYDYLTVPSDRFEQQAKISEDDIKSYYNQHHKKFMTSEQVTLDYVLLSMHDIKSQI
KISPDEIKSYYEENKSNYLTPAQWRVAHILFAVPENATKEEQDSIKQKADEVYNDLKKHPEQFDKYVASKSDDKLSIANK
GILPWITGGQNEYDRVLSNLTRPGQISIPVQTKYGYEIFKLIAYKPVTTKSLQEVENIIKDQLTSDMAQAKYAQVLEQLT
DLSYQTPDSLDPVLDSLKLKIQHTEPFSRYGGKQPITKNKQVIHAAFSTDVLELGNNSEPIQIDNDSVIVLRVKKHIPSR
EQTLDEVRDQIKKVLAKQYGDAKAKEIGSSLLHPVEDKQQQELIANNQFEWHSVENASRDSDKANSLINDLAFNLLRPES
RDGVILDNGDYVVVKLKRINDGKLSSLDQEQRDSLIQQIEASYGMMDYDLYVNNLLHHAKIERK

Sequences:

>Translated_624_residues
MLQKLNEHIQGVVAWLVIILIAITFTLFGVDYYFQSRQISDAKVIVNDKPITMQAFETNYRRTRAQQDLPQMTAADEKNL
QNQVLNQMITNEVSIQAARKYGFEVSPEQANAAIVQIPQFQEDGHFSAQRYQQALSGALFTPETFQKEVRQGMLLNQQRF
AFMGTSFALSDEIKRFVRLYMQTRDYDYLTVPSDRFEQQAKISEDDIKSYYNQHHKKFMTSEQVTLDYVLLSMHDIKSQI
KISPDEIKSYYEENKSNYLTPAQWRVAHILFAVPENATKEEQDSIKQKADEVYNDLKKHPEQFDKYVASKSDDKLSIANK
GILPWITGGQNEYDRVLSNLTRPGQISIPVQTKYGYEIFKLIAYKPVTTKSLQEVENIIKDQLTSDMAQAKYAQVLEQLT
DLSYQTPDSLDPVLDSLKLKIQHTEPFSRYGGKQPITKNKQVIHAAFSTDVLELGNNSEPIQIDNDSVIVLRVKKHIPSR
EQTLDEVRDQIKKVLAKQYGDAKAKEIGSSLLHPVEDKQQQELIANNQFEWHSVENASRDSDKANSLINDLAFNLLRPES
RDGVILDNGDYVVVKLKRINDGKLSSLDQEQRDSLIQQIEASYGMMDYDLYVNNLLHHAKIERK
>Mature_624_residues
MLQKLNEHIQGVVAWLVIILIAITFTLFGVDYYFQSRQISDAKVIVNDKPITMQAFETNYRRTRAQQDLPQMTAADEKNL
QNQVLNQMITNEVSIQAARKYGFEVSPEQANAAIVQIPQFQEDGHFSAQRYQQALSGALFTPETFQKEVRQGMLLNQQRF
AFMGTSFALSDEIKRFVRLYMQTRDYDYLTVPSDRFEQQAKISEDDIKSYYNQHHKKFMTSEQVTLDYVLLSMHDIKSQI
KISPDEIKSYYEENKSNYLTPAQWRVAHILFAVPENATKEEQDSIKQKADEVYNDLKKHPEQFDKYVASKSDDKLSIANK
GILPWITGGQNEYDRVLSNLTRPGQISIPVQTKYGYEIFKLIAYKPVTTKSLQEVENIIKDQLTSDMAQAKYAQVLEQLT
DLSYQTPDSLDPVLDSLKLKIQHTEPFSRYGGKQPITKNKQVIHAAFSTDVLELGNNSEPIQIDNDSVIVLRVKKHIPSR
EQTLDEVRDQIKKVLAKQYGDAKAKEIGSSLLHPVEDKQQQELIANNQFEWHSVENASRDSDKANSLINDLAFNLLRPES
RDGVILDNGDYVVVKLKRINDGKLSSLDQEQRDSLIQQIEASYGMMDYDLYVNNLLHHAKIERK

Specific function: PPIases accelerate the folding of proteins. Seems to be involved in the folding of outer membrane proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein; Periplasmic side (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786645, Length=640, Percent_Identity=26.09375, Blast_Score=170, Evalue=3e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 71799; Mature: 71799

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQKLNEHIQGVVAWLVIILIAITFTLFGVDYYFQSRQISDAKVIVNDKPITMQAFETNY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCEEHHHHHHH
RRTRAQQDLPQMTAADEKNLQNQVLNQMITNEVSIQAARKYGFEVSPEQANAAIVQIPQF
HHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCC
QEDGHFSAQRYQQALSGALFTPETFQKEVRQGMLLNQQRFAFMGTSFALSDEIKRFVRLY
CCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHH
MQTRDYDYLTVPSDRFEQQAKISEDDIKSYYNQHHKKFMTSEQVTLDYVLLSMHDIKSQI
HHHCCCCEEECCCHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
KISPDEIKSYYEENKSNYLTPAQWRVAHILFAVPENATKEEQDSIKQKADEVYNDLKKHP
CCCHHHHHHHHHHCCCCCCCCHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHCH
EQFDKYVASKSDDKLSIANKGILPWITGGQNEYDRVLSNLTRPGQISIPVQTKYGYEIFK
HHHHHHHHCCCCCCEECCCCCCCCEECCCCCHHHHHHHHCCCCCEEEEEEECCCCHHHHH
LIAYKPVTTKSLQEVENIIKDQLTSDMAQAKYAQVLEQLTDLSYQTPDSLDPVLDSLKLK
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHEEE
IQHTEPFSRYGGKQPITKNKQVIHAAFSTDVLELGNNSEPIQIDNDSVIVLRVKKHIPSR
EECCCCHHHCCCCCCCCCCCHHEEHHHHHHHHHCCCCCCCEEECCCCEEEEEEHHHCCCH
EQTLDEVRDQIKKVLAKQYGDAKAKEIGSSLLHPVEDKQQQELIANNQFEWHSVENASRD
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCCC
SDKANSLINDLAFNLLRPESRDGVILDNGDYVVVKLKRINDGKLSSLDQEQRDSLIQQIE
CHHHHHHHHHHHHHHCCCCCCCCEEEECCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHH
ASYGMMDYDLYVNNLLHHAKIERK
HHCCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLQKLNEHIQGVVAWLVIILIAITFTLFGVDYYFQSRQISDAKVIVNDKPITMQAFETNY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCEEHHHHHHH
RRTRAQQDLPQMTAADEKNLQNQVLNQMITNEVSIQAARKYGFEVSPEQANAAIVQIPQF
HHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCC
QEDGHFSAQRYQQALSGALFTPETFQKEVRQGMLLNQQRFAFMGTSFALSDEIKRFVRLY
CCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHH
MQTRDYDYLTVPSDRFEQQAKISEDDIKSYYNQHHKKFMTSEQVTLDYVLLSMHDIKSQI
HHHCCCCEEECCCHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
KISPDEIKSYYEENKSNYLTPAQWRVAHILFAVPENATKEEQDSIKQKADEVYNDLKKHP
CCCHHHHHHHHHHCCCCCCCCHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHCH
EQFDKYVASKSDDKLSIANKGILPWITGGQNEYDRVLSNLTRPGQISIPVQTKYGYEIFK
HHHHHHHHCCCCCCEECCCCCCCCEECCCCCHHHHHHHHCCCCCEEEEEEECCCCHHHHH
LIAYKPVTTKSLQEVENIIKDQLTSDMAQAKYAQVLEQLTDLSYQTPDSLDPVLDSLKLK
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHEEE
IQHTEPFSRYGGKQPITKNKQVIHAAFSTDVLELGNNSEPIQIDNDSVIVLRVKKHIPSR
EECCCCHHHCCCCCCCCCCCHHEEHHHHHHHHHCCCCCCCEEECCCCEEEEEEHHHCCCH
EQTLDEVRDQIKKVLAKQYGDAKAKEIGSSLLHPVEDKQQQELIANNQFEWHSVENASRD
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCCC
SDKANSLINDLAFNLLRPESRDGVILDNGDYVVVKLKRINDGKLSSLDQEQRDSLIQQIE
CHHHHHHHHHHHHHHCCCCCCCCEEEECCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHH
ASYGMMDYDLYVNNLLHHAKIERK
HHCCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]