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The map label for this gene is oxyR [H]

Identifier: 54294702

GI number: 54294702

Start: 1990571

End: 1991461

Strand: Reverse

Name: oxyR [H]

Synonym: lpl1779

Alternate gene names: 54294702

Gene position: 1991461-1990571 (Counterclockwise)

Preceding gene: 54294704

Following gene: 54294697

Centisome position: 59.52

GC content: 39.06

Gene sequence:

>891_bases
ATGAATTTAAGAGATTTACATTATTTTGTCATCCTGGCTGATGTAAAGCATTTTGGTGAAGCCGCTAAGAGGTGTTTTGT
AAGTCAGCCCACGTTGAGTATGCAAATAAAAAAGCTGGAAGAAGAATTAGGTGTTGTATTATTTGAGCGTACCAACAAAC
AGGTTTTACTAACTGATCAAGGCTCCAAATTATTAGATCGAACTAGAAAAATATTAATCCTGATTGATGAAATGAAAGAA
CTTGCTCGTCAGTCGGAAGATCCATTTACAGGTGAATTGCGTTTGGGGGTTATACCTACCGTATCGCCTTACATGTTGCC
CTTGGTAATGCCCGAACTTAAAAATGAGTACCCTCGCCTGAAAGTTTGGTTAATAGAGGATCAAACTCATAGATTAATTA
CTAAATTGGAGCAAGGAGAACTGGATGTTGCTATCATGGCACTTCCAATAGATAAGCGTTTTTCATGTCAAATTTTATAT
GAAGAAAAGTTCTATTTTGCTTGCGCAAATACTCATCCTTTGGCCCAAGCCAAATCAGTTAATATCAATGACTTAAAAAA
TCAGCCGATTATGTTGCTAGAAGAAGGGCATTGCCTGAGGGAGCAAGCCATGGCCGTATGTCAATCAGCGAAAGCTGACG
ACATCGCAGATTTTACTGCTACCAGTTTGGAAACCTTGAGATTAATGGTACAAGCTGGAATGGGCGTCACTTTACTGCCC
GCTTTGTCTACACTAACTGCCTCAACCAATCATTTAAAATGTATTCCTTTTTCTGAGCCAGCACCCTCTCGTATCGTGGG
GTTATTTTGGCGAGCAGGAACGCCGCGACAAATTTGTTTTAATGCAATTGCTGAATTAATAACAAAAAATGTTCAATCCA
AATTAGCATAG

Upstream 100 bases:

>100_bases
AATCAATAATTCTGTATGTATTTCGTAAAATTTGAAAAATGATTTTTGTACTGCCGATTTGTAATTTGTGTCACAATAGA
ATTTTTATTATTGAGAAATT

Downstream 100 bases:

>100_bases
AAATTATTATAAATTATACGTAAATTCCTGCTTACCTGGATGAGCTTTCATGAAGCTATTTTATGAATTTTAACTAGCAT
TCCTAACTGAGGATGATCAA

Product: hydrogen peroxide-inducible genes activator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MNLRDLHYFVILADVKHFGEAAKRCFVSQPTLSMQIKKLEEELGVVLFERTNKQVLLTDQGSKLLDRTRKILILIDEMKE
LARQSEDPFTGELRLGVIPTVSPYMLPLVMPELKNEYPRLKVWLIEDQTHRLITKLEQGELDVAIMALPIDKRFSCQILY
EEKFYFACANTHPLAQAKSVNINDLKNQPIMLLEEGHCLREQAMAVCQSAKADDIADFTATSLETLRLMVQAGMGVTLLP
ALSTLTASTNHLKCIPFSEPAPSRIVGLFWRAGTPRQICFNAIAELITKNVQSKLA

Sequences:

>Translated_296_residues
MNLRDLHYFVILADVKHFGEAAKRCFVSQPTLSMQIKKLEEELGVVLFERTNKQVLLTDQGSKLLDRTRKILILIDEMKE
LARQSEDPFTGELRLGVIPTVSPYMLPLVMPELKNEYPRLKVWLIEDQTHRLITKLEQGELDVAIMALPIDKRFSCQILY
EEKFYFACANTHPLAQAKSVNINDLKNQPIMLLEEGHCLREQAMAVCQSAKADDIADFTATSLETLRLMVQAGMGVTLLP
ALSTLTASTNHLKCIPFSEPAPSRIVGLFWRAGTPRQICFNAIAELITKNVQSKLA
>Mature_296_residues
MNLRDLHYFVILADVKHFGEAAKRCFVSQPTLSMQIKKLEEELGVVLFERTNKQVLLTDQGSKLLDRTRKILILIDEMKE
LARQSEDPFTGELRLGVIPTVSPYMLPLVMPELKNEYPRLKVWLIEDQTHRLITKLEQGELDVAIMALPIDKRFSCQILY
EEKFYFACANTHPLAQAKSVNINDLKNQPIMLLEEGHCLREQAMAVCQSAKADDIADFTATSLETLRLMVQAGMGVTLLP
ALSTLTASTNHLKCIPFSEPAPSRIVGLFWRAGTPRQICFNAIAELITKNVQSKLA

Specific function: Required for the induction of a regulon of hydrogen peroxide inducible genes such as catalase and glutathione- reductase [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=292, Percent_Identity=44.8630136986301, Blast_Score=249, Evalue=1e-67,
Organism=Escherichia coli, GI145693105, Length=273, Percent_Identity=32.2344322344322, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1787879, Length=277, Percent_Identity=29.2418772563177, Blast_Score=117, Evalue=7e-28,
Organism=Escherichia coli, GI157672245, Length=269, Percent_Identity=29.7397769516729, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI2367136, Length=240, Percent_Identity=29.5833333333333, Blast_Score=98, Evalue=8e-22,
Organism=Escherichia coli, GI1788887, Length=285, Percent_Identity=29.4736842105263, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1787601, Length=184, Percent_Identity=30.9782608695652, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1787530, Length=254, Percent_Identity=25.1968503937008, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1790208, Length=243, Percent_Identity=29.2181069958848, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1788748, Length=246, Percent_Identity=26.8292682926829, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1788297, Length=247, Percent_Identity=27.9352226720648, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI87081904, Length=212, Percent_Identity=26.8867924528302, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1787806, Length=280, Percent_Identity=25, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1788626, Length=240, Percent_Identity=26.6666666666667, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788296, Length=224, Percent_Identity=25.4464285714286, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI87082132, Length=271, Percent_Identity=23.9852398523985, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1786401, Length=237, Percent_Identity=25.3164556962025, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788481, Length=288, Percent_Identity=24.6527777777778, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1787128, Length=160, Percent_Identity=30.625, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1789204, Length=268, Percent_Identity=22.7611940298507, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33425; Mature: 33425

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLRDLHYFVILADVKHFGEAAKRCFVSQPTLSMQIKKLEEELGVVLFERTNKQVLLTDQ
CCCCCEEEEEEEHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCEEEEECCCCEEEEECC
GSKLLDRTRKILILIDEMKELARQSEDPFTGELRLGVIPTVSPYMLPLVMPELKNEYPRL
CHHHHHCCCEEEEEHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCE
KVWLIEDQTHRLITKLEQGELDVAIMALPIDKRFSCQILYEEKFYFACANTHPLAQAKSV
EEEEEECCHHHHHHHHCCCCCCEEEEEEECCCCCEEEEEEECEEEEEECCCCCCCCCCCC
NINDLKNQPIMLLEEGHCLREQAMAVCQSAKADDIADFTATSLETLRLMVQAGMGVTLLP
CHHHCCCCCEEEEECCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCEEHHH
ALSTLTASTNHLKCIPFSEPAPSRIVGLFWRAGTPRQICFNAIAELITKNVQSKLA
HHHHHHCCCCCEEEEECCCCCCCHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNLRDLHYFVILADVKHFGEAAKRCFVSQPTLSMQIKKLEEELGVVLFERTNKQVLLTDQ
CCCCCEEEEEEEHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCEEEEECCCCEEEEECC
GSKLLDRTRKILILIDEMKELARQSEDPFTGELRLGVIPTVSPYMLPLVMPELKNEYPRL
CHHHHHCCCEEEEEHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCE
KVWLIEDQTHRLITKLEQGELDVAIMALPIDKRFSCQILYEEKFYFACANTHPLAQAKSV
EEEEEECCHHHHHHHHCCCCCCEEEEEEECCCCCEEEEEEECEEEEEECCCCCCCCCCCC
NINDLKNQPIMLLEEGHCLREQAMAVCQSAKADDIADFTATSLETLRLMVQAGMGVTLLP
CHHHCCCCCEEEEECCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCEEHHH
ALSTLTASTNHLKCIPFSEPAPSRIVGLFWRAGTPRQICFNAIAELITKNVQSKLA
HHHHHHCCCCCEEEEECCCCCCCHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 8890216 [H]