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The map label for this gene is fliD [H]

Identifier: 54294226

GI number: 54294226

Start: 1442052

End: 1443677

Strand: Reverse

Name: fliD [H]

Synonym: lpl1291

Alternate gene names: 54294226

Gene position: 1443677-1442052 (Counterclockwise)

Preceding gene: 54294227

Following gene: 54294225

Centisome position: 43.15

GC content: 38.87

Gene sequence:

>1626_bases
ATGGAACTCTCTTCACCAGGCGTAGGGTCAGGACTTGATGTAAAAAACCTGGTCGATGCGATAGTCACGGCAGAAATAAC
CCCATCGCAAGTGCGTCATGATAAACAGTTAAATAGTGTCAATACAGAGTTGTCGGCGCTTGGTCAATTAAAAAGCTATT
TAACTAACTTGCAAACTTCGTTAGCCAAGCTCTCCAGTCTTAGCCAATTCTACACTATGAAATCAACTATTAGTGATCCG
AATTACTTTTCCGCTACTCTGGGGACTGGCGCGACTAAAAATACTTATCAAATTGAAATACAAAAACTGGCGCAACAACA
CAGTCTGGCAAGCTCTTACATGACTAATACTGGAAGCGGAACAATAACCGTAGATTTTGGAACCTATAACAGTGATAAAA
CCACTTTTACACCGAATCCTTCCGCTACATCAGTCAACATAACCATTGCGCCTGGCAACGATAGCCTTGTTGCAGTGCGA
GATGCTATTAATAATACTAATTCAGGAATAACAGCCGGCATAGTTCAAGATGGCCAGGGCTCCAGGCTAACTATCACTTC
GTTAAAAACCGGCGAAAATTATGCCATGAAAATTAGTGGTGGAGTTGCCTCATTGAATTATGATCCTACCATGGGAGTGA
ATTCATTAACTGAAACAGTAGCGGCACAAAACAGTACTGTTAAAATTAACGGATTAACTTTGGTTCAAAGTTCTAATCAA
TTGAATGAGGCAATAACTGGTGTCAGCATTGATCTAAAGAAAGCAGAGATTGGGAAAGTTGTTACCTTAACTGTTGATGA
TAATAAAGATCAGCTAACAGGCTTAATCAACGAGTTTATAAAACAATATAATGACACCATGACTTTTTTAACCAACTTAA
CTGGTTATAACAATGAAACCAAACAAGGAGGAGTATTTCAGGGCGACCCTCAATTTCGCAATTTAAAACTCAATTTAAAC
AAGTGGGCAACTACCCCTTTAGCTAACCAGGAAGGACCAATCCGCTCATTAGCTGATTTGGGGATCATCACCAATAAACA
AGGTTTACTGGAAATCAAACAAGACAAGTTTAAAACTGCACTCGATAATCACTATAAAGAAATAGGAGCATTGTTTGCAA
AAACAGCCAAGGCTAATGATAATGGCGTAAACATCAAATCCATTAATTCAACTGTCAAATCAGGTACCTATGATGTGGTG
TTGACTGAATTTACTCCTGGAGTCAGCATGTCTGGAACAATAGGAGGCTTATCTGCTACATCATCTGATGGCATTACATT
GACAGGAAGTGCTGATTTGAGTGGTCTGTCGATCAATGTATTTTCAGGGTCTGCCGGCTCCCGTGGACAAATAACTGTTA
CAGATGGTATTGCAGTCCAATTAAGTTCCTTGCTGGATGCTTACATTGAAATTAAAGGCGATTTGGAGCAGAGAAAAGAT
CAACTCAATAATCAAGTCAAGCAATTGAATAAAATACAAAACGAAATTGATATCAGGCGCAAATCAATTGAAACTCGCTA
TTTAAAACAATTCACTGCTCTGGACACTCTACTCAGCCAATTACAAAGCACTAGTGTTTTTCTATCCCAGCAATTGGCCA
ATTTACCCCAATTAAAATTGAAATAA

Upstream 100 bases:

>100_bases
ATGATATTATTAGTGGTTCTATAGACAAGCACGTTTAATAATTTGAAATATTTATTAAACATTTGACTAGAACAATAACA
ACATAGAAAAGGGATACTCT

Downstream 100 bases:

>100_bases
TAGGAGGTAATGAGAATGAAAAACCTATATTCACAAATTTCCAGCCAATACAAAGCCATAGAGCTACAAACTCGCATAGA
AGCAGCCTCCCCTCATGAAC

Product: hypothetical protein

Products: NA

Alternate protein names: HAP2; Filament cap protein [H]

Number of amino acids: Translated: 541; Mature: 541

Protein sequence:

>541_residues
MELSSPGVGSGLDVKNLVDAIVTAEITPSQVRHDKQLNSVNTELSALGQLKSYLTNLQTSLAKLSSLSQFYTMKSTISDP
NYFSATLGTGATKNTYQIEIQKLAQQHSLASSYMTNTGSGTITVDFGTYNSDKTTFTPNPSATSVNITIAPGNDSLVAVR
DAINNTNSGITAGIVQDGQGSRLTITSLKTGENYAMKISGGVASLNYDPTMGVNSLTETVAAQNSTVKINGLTLVQSSNQ
LNEAITGVSIDLKKAEIGKVVTLTVDDNKDQLTGLINEFIKQYNDTMTFLTNLTGYNNETKQGGVFQGDPQFRNLKLNLN
KWATTPLANQEGPIRSLADLGIITNKQGLLEIKQDKFKTALDNHYKEIGALFAKTAKANDNGVNIKSINSTVKSGTYDVV
LTEFTPGVSMSGTIGGLSATSSDGITLTGSADLSGLSINVFSGSAGSRGQITVTDGIAVQLSSLLDAYIEIKGDLEQRKD
QLNNQVKQLNKIQNEIDIRRKSIETRYLKQFTALDTLLSQLQSTSVFLSQQLANLPQLKLK

Sequences:

>Translated_541_residues
MELSSPGVGSGLDVKNLVDAIVTAEITPSQVRHDKQLNSVNTELSALGQLKSYLTNLQTSLAKLSSLSQFYTMKSTISDP
NYFSATLGTGATKNTYQIEIQKLAQQHSLASSYMTNTGSGTITVDFGTYNSDKTTFTPNPSATSVNITIAPGNDSLVAVR
DAINNTNSGITAGIVQDGQGSRLTITSLKTGENYAMKISGGVASLNYDPTMGVNSLTETVAAQNSTVKINGLTLVQSSNQ
LNEAITGVSIDLKKAEIGKVVTLTVDDNKDQLTGLINEFIKQYNDTMTFLTNLTGYNNETKQGGVFQGDPQFRNLKLNLN
KWATTPLANQEGPIRSLADLGIITNKQGLLEIKQDKFKTALDNHYKEIGALFAKTAKANDNGVNIKSINSTVKSGTYDVV
LTEFTPGVSMSGTIGGLSATSSDGITLTGSADLSGLSINVFSGSAGSRGQITVTDGIAVQLSSLLDAYIEIKGDLEQRKD
QLNNQVKQLNKIQNEIDIRRKSIETRYLKQFTALDTLLSQLQSTSVFLSQQLANLPQLKLK
>Mature_541_residues
MELSSPGVGSGLDVKNLVDAIVTAEITPSQVRHDKQLNSVNTELSALGQLKSYLTNLQTSLAKLSSLSQFYTMKSTISDP
NYFSATLGTGATKNTYQIEIQKLAQQHSLASSYMTNTGSGTITVDFGTYNSDKTTFTPNPSATSVNITIAPGNDSLVAVR
DAINNTNSGITAGIVQDGQGSRLTITSLKTGENYAMKISGGVASLNYDPTMGVNSLTETVAAQNSTVKINGLTLVQSSNQ
LNEAITGVSIDLKKAEIGKVVTLTVDDNKDQLTGLINEFIKQYNDTMTFLTNLTGYNNETKQGGVFQGDPQFRNLKLNLN
KWATTPLANQEGPIRSLADLGIITNKQGLLEIKQDKFKTALDNHYKEIGALFAKTAKANDNGVNIKSINSTVKSGTYDVV
LTEFTPGVSMSGTIGGLSATSSDGITLTGSADLSGLSINVFSGSAGSRGQITVTDGIAVQLSSLLDAYIEIKGDLEQRKD
QLNNQVKQLNKIQNEIDIRRKSIETRYLKQFTALDTLLSQLQSTSVFLSQQLANLPQLKLK

Specific function: Required for the morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the

COG id: COG1345

COG function: function code N; Flagellar capping protein

Gene ontology:

Cell location: Secreted. Bacterial flagellum [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fliD family [H]

Homologues:

Organism=Escherichia coli, GI1788233, Length=550, Percent_Identity=27.4545454545455, Blast_Score=130, Evalue=2e-31,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010809
- InterPro:   IPR003481 [H]

Pfam domain/function: PF07195 FliD_C; PF02465 FliD_N [H]

EC number: NA

Molecular weight: Translated: 57918; Mature: 57918

Theoretical pI: Translated: 6.83; Mature: 6.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELSSPGVGSGLDVKNLVDAIVTAEITPSQVRHDKQLNSVNTELSALGQLKSYLTNLQTS
CCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAKLSSLSQFYTMKSTISDPNYFSATLGTGATKNTYQIEIQKLAQQHSLASSYMTNTGSG
HHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCCCC
TITVDFGTYNSDKTTFTPNPSATSVNITIAPGNDSLVAVRDAINNTNSGITAGIVQDGQG
EEEEEECCCCCCCEEECCCCCCEEEEEEEECCCCCEEEEEHHCCCCCCCEEEEEEECCCC
SRLTITSLKTGENYAMKISGGVASLNYDPTMGVNSLTETVAAQNSTVKINGLTLVQSSNQ
CEEEEEEEECCCCEEEEEECCEEEECCCCCCCHHHHHHHHHCCCCEEEEEEEEEEECCCH
LNEAITGVSIDLKKAEIGKVVTLTVDDNKDQLTGLINEFIKQYNDTMTFLTNLTGYNNET
HHHHHCCCEEEEEECCCCEEEEEEECCCHHHHHHHHHHHHHHHCCCEEEHHHCCCCCCCC
KQGGVFQGDPQFRNLKLNLNKWATTPLANQEGPIRSLADLGIITNKQGLLEIKQDKFKTA
CCCCEECCCCCCEEEEEEECCEECCCCCCCCCCHHHHHHCCEEECCCCCEEEHHHHHHHH
LDNHYKEIGALFAKTAKANDNGVNIKSINSTVKSGTYDVVLTEFTPGVSMSGTIGGLSAT
HHHHHHHHHHHHHHHCCCCCCCCEEEECCHHHCCCCEEEEEEECCCCCCCCCCCCCCCCC
SSDGITLTGSADLSGLSINVFSGSAGSRGQITVTDGIAVQLSSLLDAYIEIKGDLEQRKD
CCCCEEEECCCCCCCEEEEEEECCCCCCCEEEEECCHHHHHHHHHHHHHEECCCHHHHHH
QLNNQVKQLNKIQNEIDIRRKSIETRYLKQFTALDTLLSQLQSTSVFLSQQLANLPQLKL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
K
C
>Mature Secondary Structure
MELSSPGVGSGLDVKNLVDAIVTAEITPSQVRHDKQLNSVNTELSALGQLKSYLTNLQTS
CCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAKLSSLSQFYTMKSTISDPNYFSATLGTGATKNTYQIEIQKLAQQHSLASSYMTNTGSG
HHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCCCC
TITVDFGTYNSDKTTFTPNPSATSVNITIAPGNDSLVAVRDAINNTNSGITAGIVQDGQG
EEEEEECCCCCCCEEECCCCCCEEEEEEEECCCCCEEEEEHHCCCCCCCEEEEEEECCCC
SRLTITSLKTGENYAMKISGGVASLNYDPTMGVNSLTETVAAQNSTVKINGLTLVQSSNQ
CEEEEEEEECCCCEEEEEECCEEEECCCCCCCHHHHHHHHHCCCCEEEEEEEEEEECCCH
LNEAITGVSIDLKKAEIGKVVTLTVDDNKDQLTGLINEFIKQYNDTMTFLTNLTGYNNET
HHHHHCCCEEEEEECCCCEEEEEEECCCHHHHHHHHHHHHHHHCCCEEEHHHCCCCCCCC
KQGGVFQGDPQFRNLKLNLNKWATTPLANQEGPIRSLADLGIITNKQGLLEIKQDKFKTA
CCCCEECCCCCCEEEEEEECCEECCCCCCCCCCHHHHHHCCEEECCCCCEEEHHHHHHHH
LDNHYKEIGALFAKTAKANDNGVNIKSINSTVKSGTYDVVLTEFTPGVSMSGTIGGLSAT
HHHHHHHHHHHHHHHCCCCCCCCEEEECCHHHCCCCEEEEEEECCCCCCCCCCCCCCCCC
SSDGITLTGSADLSGLSINVFSGSAGSRGQITVTDGIAVQLSSLLDAYIEIKGDLEQRKD
CCCCEEEECCCCCCCEEEEEEECCCCCCCEEEEECCHHHHHHHHHHHHHEECCCHHHHHH
QLNNQVKQLNKIQNEIDIRRKSIETRYLKQFTALDTLLSQLQSTSVFLSQQLANLPQLKL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
K
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1527488; 9097040; 9278503; 2659972; 6305924 [H]