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The map label for this gene is qseC [H]

Identifier: 54294189

GI number: 54294189

Start: 1394904

End: 1396319

Strand: Reverse

Name: qseC [H]

Synonym: lpl1253

Alternate gene names: 54294189

Gene position: 1396319-1394904 (Counterclockwise)

Preceding gene: 54294190

Following gene: 54294184

Centisome position: 41.73

GC content: 36.86

Gene sequence:

>1416_bases
GTGAAATCGTCCATTCGAAAATTTTTATTAATTAATCTGCTTCTTGCAATTACTATTACTACAACATTAACTGCTATTGG
TAACTATTATCTTGATCAAAAAGACATTCAAGACCACCTTGATACATTGATGGCTATTTCCGCACTATCCTATCAAGCCT
TATTAGGGGATGATCTTCATCAAAGGCCTCTTGCAAAAATTCAAAATGCCCTGGAATCTATTCCCCAAAAAATTAATACT
TATTATCAAAAAAGATATTTAAATGATGAGCCTCAAGAAAATTATTTGGATAAATTTAATTTTCAGGTATGGACCAATGG
AGGTAAATTATTATTACATTCACCCACTGCCCCTAAAATACCATTAACAGCAGAGACAGACGGCTTTAGCGATAAAAGAA
TTTCTAACCAGAATTGGCGAGTATTCACAACTTATAATGACAAAGCAGGGATTCGTACTGTACTGGCAGAGCGTTATGAT
ACCAGAAATGAGCTGGGTCACAGAATTGCCCAAGATGACCTCTATATTATGTTGCTTACTTTTCCATTATCAGGACTATT
AATATGGATCATTATTGGAAGAGGACTAGACAGTCTGGATAGAGTAGCAGAAGAGGTTGCTAACCGTGCGCCAAGTCACC
TGGAACCTGTTGATTTACAAGAAGTTCCCGAAGAAATTAAACCTGTAATTGATGAATTGAATAAATTATTTTTTCGACTC
AAAGAAGGGTTTGAGCGTGAAAAACGATTTGCTGCCGATGCAGCACATGAATTGAGAACACCTCTTGCAGCACTTAAGGC
CCAAGCTCAAGTGGCTTTGAACTCTAATGAGATAGAAGAAAAAAATCAGGCTTTACAAAAATTAATTGCCAGCGTTAATC
GAAGCACACATATAGTGCAGCAGTTGCTAACCATGAGTAAACTTGTACCAGAAGCAACAGAACTACATGAGCAAGATGAA
GTCAATCTAAGTAAATTAACTCGTGAAATATTAGCCATGTTGGCTCCGTCTGCGGTCGAAAAACAAATTGAGCTGGAATT
TGAAACCGATGAAAAAATGCCTAAAATTTATGGAAATCCAACGGCTTTGGGAATATTAATACGCAATCTGGTTGACAATT
CCATTCGATATTCCATGGAAAATGGAAGAGTTATTGTTCGATTATTAAAACATAATAACGAAATCATACTCGAAGTATGT
GATAATGGCCCAGGGATACCACCTGAATTACAAAAACGTGTTTTTGAAAGATTTTTTAGAGTATTAGGGAACAAAAGCCC
GGGTAGCGGTCTGGGTTTGGCTATCGTGCAACAAATATGCGAACTTCATGGTGGAAGGGTCGTGCTTGATTCACCTAAAA
TTGGCACAGGCCTAATTGTGAGAGTTTATTTACCCATCAAAACAAAACCAAAATAA

Upstream 100 bases:

>100_bases
TTCATATCCATAATTTACGTAAAAAACTTAACGCAAACTTTATCCGCACTATACGTGGTGTAGGATATATGGCTGAAAAA
AATGACAGTGTACTTCTATC

Downstream 100 bases:

>100_bases
ACTCAATAATCAAATCATAATCTTGCTGTAATTAACCTTTTTAGCTTGGAGAATCTGCTTCATGTTTCTGTGTATCGGTC
GCAGTCTTCGCTTCTTCTTC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 471; Mature: 471

Protein sequence:

>471_residues
MKSSIRKFLLINLLLAITITTTLTAIGNYYLDQKDIQDHLDTLMAISALSYQALLGDDLHQRPLAKIQNALESIPQKINT
YYQKRYLNDEPQENYLDKFNFQVWTNGGKLLLHSPTAPKIPLTAETDGFSDKRISNQNWRVFTTYNDKAGIRTVLAERYD
TRNELGHRIAQDDLYIMLLTFPLSGLLIWIIIGRGLDSLDRVAEEVANRAPSHLEPVDLQEVPEEIKPVIDELNKLFFRL
KEGFEREKRFAADAAHELRTPLAALKAQAQVALNSNEIEEKNQALQKLIASVNRSTHIVQQLLTMSKLVPEATELHEQDE
VNLSKLTREILAMLAPSAVEKQIELEFETDEKMPKIYGNPTALGILIRNLVDNSIRYSMENGRVIVRLLKHNNEIILEVC
DNGPGIPPELQKRVFERFFRVLGNKSPGSGLGLAIVQQICELHGGRVVLDSPKIGTGLIVRVYLPIKTKPK

Sequences:

>Translated_471_residues
MKSSIRKFLLINLLLAITITTTLTAIGNYYLDQKDIQDHLDTLMAISALSYQALLGDDLHQRPLAKIQNALESIPQKINT
YYQKRYLNDEPQENYLDKFNFQVWTNGGKLLLHSPTAPKIPLTAETDGFSDKRISNQNWRVFTTYNDKAGIRTVLAERYD
TRNELGHRIAQDDLYIMLLTFPLSGLLIWIIIGRGLDSLDRVAEEVANRAPSHLEPVDLQEVPEEIKPVIDELNKLFFRL
KEGFEREKRFAADAAHELRTPLAALKAQAQVALNSNEIEEKNQALQKLIASVNRSTHIVQQLLTMSKLVPEATELHEQDE
VNLSKLTREILAMLAPSAVEKQIELEFETDEKMPKIYGNPTALGILIRNLVDNSIRYSMENGRVIVRLLKHNNEIILEVC
DNGPGIPPELQKRVFERFFRVLGNKSPGSGLGLAIVQQICELHGGRVVLDSPKIGTGLIVRVYLPIKTKPK
>Mature_471_residues
MKSSIRKFLLINLLLAITITTTLTAIGNYYLDQKDIQDHLDTLMAISALSYQALLGDDLHQRPLAKIQNALESIPQKINT
YYQKRYLNDEPQENYLDKFNFQVWTNGGKLLLHSPTAPKIPLTAETDGFSDKRISNQNWRVFTTYNDKAGIRTVLAERYD
TRNELGHRIAQDDLYIMLLTFPLSGLLIWIIIGRGLDSLDRVAEEVANRAPSHLEPVDLQEVPEEIKPVIDELNKLFFRL
KEGFEREKRFAADAAHELRTPLAALKAQAQVALNSNEIEEKNQALQKLIASVNRSTHIVQQLLTMSKLVPEATELHEQDE
VNLSKLTREILAMLAPSAVEKQIELEFETDEKMPKIYGNPTALGILIRNLVDNSIRYSMENGRVIVRLLKHNNEIILEVC
DNGPGIPPELQKRVFERFFRVLGNKSPGSGLGLAIVQQICELHGGRVVLDSPKIGTGLIVRVYLPIKTKPK

Specific function: Member of a two-component regulatory system qseB/qseC. Activates the flagella regulon by activating transcription of flhDC. May activate qseB by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789403, Length=459, Percent_Identity=30.9368191721133, Blast_Score=197, Evalue=2e-51,
Organism=Escherichia coli, GI1786783, Length=295, Percent_Identity=29.4915254237288, Blast_Score=115, Evalue=8e-27,
Organism=Escherichia coli, GI1788279, Length=301, Percent_Identity=29.2358803986711, Blast_Score=115, Evalue=8e-27,
Organism=Escherichia coli, GI1790551, Length=269, Percent_Identity=27.5092936802974, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1788393, Length=247, Percent_Identity=27.9352226720648, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1786600, Length=224, Percent_Identity=33.4821428571429, Blast_Score=99, Evalue=7e-22,
Organism=Escherichia coli, GI1790346, Length=253, Percent_Identity=29.2490118577075, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1790436, Length=223, Percent_Identity=29.5964125560538, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1786912, Length=227, Percent_Identity=31.2775330396476, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI145693157, Length=320, Percent_Identity=25.625, Blast_Score=85, Evalue=9e-18,
Organism=Escherichia coli, GI1790861, Length=275, Percent_Identity=28, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1789149, Length=258, Percent_Identity=29.8449612403101, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1788549, Length=216, Percent_Identity=26.3888888888889, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1789808, Length=304, Percent_Identity=26.6447368421053, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI87081816, Length=287, Percent_Identity=26.1324041811847, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1787894, Length=217, Percent_Identity=30.8755760368664, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI48994928, Length=238, Percent_Identity=23.5294117647059, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI87082128, Length=257, Percent_Identity=24.5136186770428, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1788713, Length=226, Percent_Identity=24.7787610619469, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1787374, Length=297, Percent_Identity=21.8855218855219, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790300, Length=280, Percent_Identity=25.7142857142857, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 53323; Mature: 53323

Theoretical pI: Translated: 6.87; Mature: 6.87

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSSIRKFLLINLLLAITITTTLTAIGNYYLDQKDIQDHLDTLMAISALSYQALLGDDLH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHH
QRPLAKIQNALESIPQKINTYYQKRYLNDEPQENYLDKFNFQVWTNGGKLLLHSPTAPKI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCEEEEECCCEEEEECCCCCCC
PLTAETDGFSDKRISNQNWRVFTTYNDKAGIRTVLAERYDTRNELGHRIAQDDLYIMLLT
CEEECCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHCCHHHHHHHHHCCCCEEEHHH
FPLSGLLIWIIIGRGLDSLDRVAEEVANRAPSHLEPVDLQEVPEEIKPVIDELNKLFFRL
HHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
KEGFEREKRFAADAAHELRTPLAALKAQAQVALNSNEIEEKNQALQKLIASVNRSTHIVQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCHHHHHHH
QLLTMSKLVPEATELHEQDEVNLSKLTREILAMLAPSAVEKQIELEFETDEKMPKIYGNP
HHHHHHHHCCHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHHEEEEECCCCCCCHHCCCH
TALGILIRNLVDNSIRYSMENGRVIVRLLKHNNEIILEVCDNGPGIPPELQKRVFERFFR
HHHHHHHHHHHHHHHHEEECCCCEEEEEECCCCEEEEEEECCCCCCCHHHHHHHHHHHHH
VLGNKSPGSGLGLAIVQQICELHGGRVVLDSPKIGTGLIVRVYLPIKTKPK
HHCCCCCCCCHHHHHHHHHHHHCCCEEEECCCCCCCCEEEEEEEECCCCCC
>Mature Secondary Structure
MKSSIRKFLLINLLLAITITTTLTAIGNYYLDQKDIQDHLDTLMAISALSYQALLGDDLH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHH
QRPLAKIQNALESIPQKINTYYQKRYLNDEPQENYLDKFNFQVWTNGGKLLLHSPTAPKI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCEEEEECCCEEEEECCCCCCC
PLTAETDGFSDKRISNQNWRVFTTYNDKAGIRTVLAERYDTRNELGHRIAQDDLYIMLLT
CEEECCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHCCHHHHHHHHHCCCCEEEHHH
FPLSGLLIWIIIGRGLDSLDRVAEEVANRAPSHLEPVDLQEVPEEIKPVIDELNKLFFRL
HHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
KEGFEREKRFAADAAHELRTPLAALKAQAQVALNSNEIEEKNQALQKLIASVNRSTHIVQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCHHHHHHH
QLLTMSKLVPEATELHEQDEVNLSKLTREILAMLAPSAVEKQIELEFETDEKMPKIYGNP
HHHHHHHHCCHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHHEEEEECCCCCCCHHCCCH
TALGILIRNLVDNSIRYSMENGRVIVRLLKHNNEIILEVCDNGPGIPPELQKRVFERFFR
HHHHHHHHHHHHHHHHEEECCCCEEEEEECCCCEEEEEEECCCCCCCHHHHHHHHHHHHH
VLGNKSPGSGLGLAIVQQICELHGGRVVLDSPKIGTGLIVRVYLPIKTKPK
HHCCCCCCCCHHHHHHHHHHHHCCCEEEECCCCCCCCEEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796; 11929534 [H]