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The map label for this gene is cfa [H]

Identifier: 54294073

GI number: 54294073

Start: 1267730

End: 1268857

Strand: Reverse

Name: cfa [H]

Synonym: lpl1137

Alternate gene names: 54294073

Gene position: 1268857-1267730 (Counterclockwise)

Preceding gene: 54294074

Following gene: 54294072

Centisome position: 37.93

GC content: 36.17

Gene sequence:

>1128_bases
ATGGATATTAAGAAAAACAAAGCAAAAACATTTGTTAATTACATGCTTCAGCTAGCCAATATCAATATCAATGGCCAAAC
ACCTTGGGATATACAAATTTATAATGATGAGTTTTATTCCAGATTATTGCGTGATGCCGATTTGGGTCTGGGTGAAAGTT
ATATGGACGGTTGGTGGGATTGTCAACGAATTGATTTATTTATTTCAAAACTGATTAACGCAAATCTTGAGTCCAAAATT
AAAATTAATTTTAAATTGGCATTTAATGTCTTTTTATCAAAAATATTGAACCTGCAAACCCAAAAACGTTCTCTGCATGT
TGGTAGACAACATTATGATAGAGGAAATGATCTGTTTCAGATTATGCTTGATAGCAACATGAACTACACTTGCGGTTATT
GGAGAAAGGCTGAAAATTTGGAGCAAGCCCAACTCGACAAACTCTATCTGACCTGCAGAAAACTCTGCCTTAAACCCGGT
ATGAAATTGCTGGATATCGGATGTGGATGGGGAGGACTTGCAAAATATGCTGCTGAAAACTATGGGGTATCAGTAGTTGG
CATAACGATATCACAGCAACAATACGAGTTAGCTAAAACGCGCTGTGCCCATTTGCCTGTTGAAATCCGATTTCAGGATT
ATAGAGACTTAAATGAAAAATTCGATCGTATAGTCTCCTTAGGGATGTTTGAGCATGTTGGTTACAAGAATTACCGAAAA
TACATGCAGATTGTCCATCAATGTTTAAATGATGATGGTTTGTTCTTATTACACACTATAGGTTCCAATGAAAGTGTCAC
AAAAGCCACACCATGGATTTCAAAATATATTTTTCCCAATGGAATGATTCCATCCATCATGCAAATAGGCCAAGCTTCCG
AAAAATTATTCGTTATGGAAGATTGGCATAATTTTGGAGCTGATTATTACAAAACATTAATGGCATGGCATGAGAATTTC
AATCAGGGATGGGACCAAATTAAATCCCAATATAGCGAAAAATTCTTTCGTATGTGGAATTATTATTTGCTCTCTTGTGC
TGGAGCTTTTGACGCCAGAATGTTGCAATTATGGCAGATTGTTTTTTCAAAGAAAGGAATTCAAGGAGGTTACTCTGTCC
CGAGGTAA

Upstream 100 bases:

>100_bases
TTATTTATTATCTTGTTACAGCCATAACAGACGCTTTGAGTGGCTGATGATGTTGCATTGATTGAATGTTTCAATATCCT
TTATAAAAAGGGAGTTTGAT

Downstream 100 bases:

>100_bases
ATGGTTTAAACAATTTATTCCGCATCGTAATACCTTCACCAGCAAACCAGGTTTTCCATGCCATGAAGTTAGCAAGATTA
TTCATATATCCCGTTAATTT

Product: cyclopropane fatty acyl phospholipid synthase

Products: NA

Alternate protein names: CFA synthase; Cyclopropane fatty acid synthase [H]

Number of amino acids: Translated: 375; Mature: 375

Protein sequence:

>375_residues
MDIKKNKAKTFVNYMLQLANININGQTPWDIQIYNDEFYSRLLRDADLGLGESYMDGWWDCQRIDLFISKLINANLESKI
KINFKLAFNVFLSKILNLQTQKRSLHVGRQHYDRGNDLFQIMLDSNMNYTCGYWRKAENLEQAQLDKLYLTCRKLCLKPG
MKLLDIGCGWGGLAKYAAENYGVSVVGITISQQQYELAKTRCAHLPVEIRFQDYRDLNEKFDRIVSLGMFEHVGYKNYRK
YMQIVHQCLNDDGLFLLHTIGSNESVTKATPWISKYIFPNGMIPSIMQIGQASEKLFVMEDWHNFGADYYKTLMAWHENF
NQGWDQIKSQYSEKFFRMWNYYLLSCAGAFDARMLQLWQIVFSKKGIQGGYSVPR

Sequences:

>Translated_375_residues
MDIKKNKAKTFVNYMLQLANININGQTPWDIQIYNDEFYSRLLRDADLGLGESYMDGWWDCQRIDLFISKLINANLESKI
KINFKLAFNVFLSKILNLQTQKRSLHVGRQHYDRGNDLFQIMLDSNMNYTCGYWRKAENLEQAQLDKLYLTCRKLCLKPG
MKLLDIGCGWGGLAKYAAENYGVSVVGITISQQQYELAKTRCAHLPVEIRFQDYRDLNEKFDRIVSLGMFEHVGYKNYRK
YMQIVHQCLNDDGLFLLHTIGSNESVTKATPWISKYIFPNGMIPSIMQIGQASEKLFVMEDWHNFGADYYKTLMAWHENF
NQGWDQIKSQYSEKFFRMWNYYLLSCAGAFDARMLQLWQIVFSKKGIQGGYSVPR
>Mature_375_residues
MDIKKNKAKTFVNYMLQLANININGQTPWDIQIYNDEFYSRLLRDADLGLGESYMDGWWDCQRIDLFISKLINANLESKI
KINFKLAFNVFLSKILNLQTQKRSLHVGRQHYDRGNDLFQIMLDSNMNYTCGYWRKAENLEQAQLDKLYLTCRKLCLKPG
MKLLDIGCGWGGLAKYAAENYGVSVVGITISQQQYELAKTRCAHLPVEIRFQDYRDLNEKFDRIVSLGMFEHVGYKNYRK
YMQIVHQCLNDDGLFLLHTIGSNESVTKATPWISKYIFPNGMIPSIMQIGQASEKLFVMEDWHNFGADYYKTLMAWHENF
NQGWDQIKSQYSEKFFRMWNYYLLSCAGAFDARMLQLWQIVFSKKGIQGGYSVPR

Specific function: Transfers a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge [H]

COG id: COG2230

COG function: function code M; Cyclopropane fatty acid synthase and related methyltransferases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CFA/CMAS family [H]

Homologues:

Organism=Escherichia coli, GI1787951, Length=364, Percent_Identity=56.8681318681319, Blast_Score=444, Evalue=1e-126,
Organism=Caenorhabditis elegans, GI133904226, Length=391, Percent_Identity=29.923273657289, Blast_Score=157, Evalue=8e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003333 [H]

Pfam domain/function: PF02353 CMAS [H]

EC number: =2.1.1.79 [H]

Molecular weight: Translated: 43920; Mature: 43920

Theoretical pI: Translated: 8.77; Mature: 8.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIKKNKAKTFVNYMLQLANININGQTPWDIQIYNDEFYSRLLRDADLGLGESYMDGWWD
CCCCHHHHHHHHHHHHHHHEEEECCCCCEEEEEECHHHHHHHHHHCCCCCCCHHHCCCHH
CQRIDLFISKLINANLESKIKINFKLAFNVFLSKILNLQTQKRSLHVGRQHYDRGNDLFQ
HHHHHHHHHHHHCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
IMLDSNMNYTCGYWRKAENLEQAQLDKLYLTCRKLCLKPGMKLLDIGCGWGGLAKYAAEN
EEECCCCCCEECCHHHHCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHC
YGVSVVGITISQQQYELAKTRCAHLPVEIRFQDYRDLNEKFDRIVSLGMFEHVGYKNYRK
CCEEEEEEEECHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
YMQIVHQCLNDDGLFLLHTIGSNESVTKATPWISKYIFPNGMIPSIMQIGQASEKLFVME
HHHHHHHHHCCCCEEEEEEECCCCCCCHHCHHHHHHCCCCCCHHHHHHHCCCCCEEEEEE
DWHNFGADYYKTLMAWHENFNQGWDQIKSQYSEKFFRMWNYYLLSCAGAFDARMLQLWQI
CHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHH
VFSKKGIQGGYSVPR
HHHHCCCCCCCCCCC
>Mature Secondary Structure
MDIKKNKAKTFVNYMLQLANININGQTPWDIQIYNDEFYSRLLRDADLGLGESYMDGWWD
CCCCHHHHHHHHHHHHHHHEEEECCCCCEEEEEECHHHHHHHHHHCCCCCCCHHHCCCHH
CQRIDLFISKLINANLESKIKINFKLAFNVFLSKILNLQTQKRSLHVGRQHYDRGNDLFQ
HHHHHHHHHHHHCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
IMLDSNMNYTCGYWRKAENLEQAQLDKLYLTCRKLCLKPGMKLLDIGCGWGGLAKYAAEN
EEECCCCCCEECCHHHHCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHC
YGVSVVGITISQQQYELAKTRCAHLPVEIRFQDYRDLNEKFDRIVSLGMFEHVGYKNYRK
CCEEEEEEEECHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
YMQIVHQCLNDDGLFLLHTIGSNESVTKATPWISKYIFPNGMIPSIMQIGQASEKLFVME
HHHHHHHHHCCCCEEEEEEECCCCCCCHHCHHHHHHCCCCCCHHHHHHHCCCCCEEEEEE
DWHNFGADYYKTLMAWHENFNQGWDQIKSQYSEKFFRMWNYYLLSCAGAFDARMLQLWQI
CHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHH
VFSKKGIQGGYSVPR
HHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]