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The map label for this gene is yfeW [C]

Identifier: 54294059

GI number: 54294059

Start: 1249131

End: 1250246

Strand: Reverse

Name: yfeW [C]

Synonym: lpl1123

Alternate gene names: 54294059

Gene position: 1250246-1249131 (Counterclockwise)

Preceding gene: 54294061

Following gene: 54294058

Centisome position: 37.37

GC content: 36.92

Gene sequence:

>1116_bases
ATGAGCCGTTATGTATGCAAGTGGAAATTGATTTATACGTTTTTCATTTTCATTGTCTTTAATAACTGTCCACTTGCCTT
TGCGAGCCCTTCCTTAACCAAGCAATTACATACCATCTTAAAAGACAACCTTGCAGACTCATTAACCCCTGGAGCAGTAT
TACTGATATCAAGTCCTGATTTGGGCACAATTTCCGTCGCGGCAGGGTTGGCAGATAAGGAAAATGATATTTCAATGAAT
ATTACGGACAGTTTTCGTCTTGCAAGCATGAGTAAAACATTTTTGGCTGTAACTGTCTTAAAACTGGTAGCAGATAAACA
GTTAAATCTTGATGATCATATTGCAGACTTATTGCCAGATAGTATAGATATTGAACGTATACCTAATGGAGATGAGGTAA
CAGTGCAACAATTACTGCAAATGCGTAGCGGCATTCCTAATTATACGGATTATGATTCTTACAGTGATCTCATTGATACT
ATGGCAGACAAGGAATGGACACCAGAAGAATGCATTAAACTAGTCTACGATAAAAAACCTGACTTTAAGCCAGGAACGGC
TTATGAGTACAGCAATACTAATTATTTGTTGCTGCAATTAATTATCGAAAACTTAACCGGAGAATCCTATGCTGAATCAA
TTAAGAAATACATCCTGAAACCTATTCGTTTAAAAAATACATATATAGAAAAGCAAGAATTTGATGACGACCACCATTAT
TTATCAACACATGGCTATACCTTGGAAGATGGCAAAGTGGTTGACGTAACAGACTATGATGATGGTTTCGGCTTGGCTGA
TGGTGGAATAATTAGTACTGCTGAAGATATTAATATCTTTATCCAGGCGTTGTTGAAAGATAAAATACTTTTATCTCCAA
ACTATTTAACAATGATGCTTACCTTTCCAGATGATTACGGTTTTGGAATAGGACGTGAAGAAATTAATGGAGAGATGGCC
TGGTCCCATAATGGGGCAAGCTCAGGATACCAAGGCCAGTACTACTATTTTCCAGACAGGCAATTGACTGTTGTTATTTT
AACCAACTATTTTGACAGTGATATCATCGAAGACATAGCATCTCAAACTCTCAGTGCGATTGACAATTCCGAATAA

Upstream 100 bases:

>100_bases
CTATTTTATACAGGAAGTAAAGAAATTATCCTGAAATCGACTAGAATTAAGATATAGCTCATTTGGTGGGTGAGAAAACC
CTTGCCACATTGGAGTTGCA

Downstream 100 bases:

>100_bases
CTGCTTAACTGCACTCATCTAATGGAAGTCCGCAAAATAGATTATATGTTATACTAAGTGAAAATTATCTGGACTTTTAT
GGGGGCAAAATATGGCTATT

Product: hypothetical protein

Products: NA

Alternate protein names: DD-carboxypeptidase; DD-peptidase [H]

Number of amino acids: Translated: 371; Mature: 370

Protein sequence:

>371_residues
MSRYVCKWKLIYTFFIFIVFNNCPLAFASPSLTKQLHTILKDNLADSLTPGAVLLISSPDLGTISVAAGLADKENDISMN
ITDSFRLASMSKTFLAVTVLKLVADKQLNLDDHIADLLPDSIDIERIPNGDEVTVQQLLQMRSGIPNYTDYDSYSDLIDT
MADKEWTPEECIKLVYDKKPDFKPGTAYEYSNTNYLLLQLIIENLTGESYAESIKKYILKPIRLKNTYIEKQEFDDDHHY
LSTHGYTLEDGKVVDVTDYDDGFGLADGGIISTAEDINIFIQALLKDKILLSPNYLTMMLTFPDDYGFGIGREEINGEMA
WSHNGASSGYQGQYYYFPDRQLTVVILTNYFDSDIIEDIASQTLSAIDNSE

Sequences:

>Translated_371_residues
MSRYVCKWKLIYTFFIFIVFNNCPLAFASPSLTKQLHTILKDNLADSLTPGAVLLISSPDLGTISVAAGLADKENDISMN
ITDSFRLASMSKTFLAVTVLKLVADKQLNLDDHIADLLPDSIDIERIPNGDEVTVQQLLQMRSGIPNYTDYDSYSDLIDT
MADKEWTPEECIKLVYDKKPDFKPGTAYEYSNTNYLLLQLIIENLTGESYAESIKKYILKPIRLKNTYIEKQEFDDDHHY
LSTHGYTLEDGKVVDVTDYDDGFGLADGGIISTAEDINIFIQALLKDKILLSPNYLTMMLTFPDDYGFGIGREEINGEMA
WSHNGASSGYQGQYYYFPDRQLTVVILTNYFDSDIIEDIASQTLSAIDNSE
>Mature_370_residues
SRYVCKWKLIYTFFIFIVFNNCPLAFASPSLTKQLHTILKDNLADSLTPGAVLLISSPDLGTISVAAGLADKENDISMNI
TDSFRLASMSKTFLAVTVLKLVADKQLNLDDHIADLLPDSIDIERIPNGDEVTVQQLLQMRSGIPNYTDYDSYSDLIDTM
ADKEWTPEECIKLVYDKKPDFKPGTAYEYSNTNYLLLQLIIENLTGESYAESIKKYILKPIRLKNTYIEKQEFDDDHHYL
STHGYTLEDGKVVDVTDYDDGFGLADGGIISTAEDINIFIQALLKDKILLSPNYLTMMLTFPDDYGFGIGREEINGEMAW
SHNGASSGYQGQYYYFPDRQLTVVILTNYFDSDIIEDIASQTLSAIDNSE

Specific function: Catalyzes distinct carboxypeptidation and transpeptidation reactions during the last stages of wall peptidoglycan synthesis. Mistaking a beta-lactam antibiotic molecule for a normal substrate (i.e., a D-alanyl-D-alanine- terminated peptide), it becomes im

COG id: COG1680

COG function: function code V; Beta-lactamase class C and other penicillin binding proteins

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S12 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001466 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: =3.4.16.4 [H]

Molecular weight: Translated: 41806; Mature: 41674

Theoretical pI: Translated: 4.14; Mature: 4.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRYVCKWKLIYTFFIFIVFNNCPLAFASPSLTKQLHTILKDNLADSLTPGAVLLISSPD
CCCCEEHHHHHHHHHHHHHHCCCCCEECCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCC
LGTISVAAGLADKENDISMNITDSFRLASMSKTFLAVTVLKLVADKQLNLDDHIADLLPD
CCEEEEEECCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCC
SIDIERIPNGDEVTVQQLLQMRSGIPNYTDYDSYSDLIDTMADKEWTPEECIKLVYDKKP
CCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCC
DFKPGTAYEYSNTNYLLLQLIIENLTGESYAESIKKYILKPIRLKNTYIEKQEFDDDHHY
CCCCCCCEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHEHHHHHCCCCCCE
LSTHGYTLEDGKVVDVTDYDDGFGLADGGIISTAEDINIFIQALLKDKILLSPNYLTMML
EECCCEEECCCEEEEEECCCCCCCCCCCCEECCHHHHHHHHHHHHHCCEEECCCEEEEEE
TFPDDYGFGIGREEINGEMAWSHNGASSGYQGQYYYFPDRQLTVVILTNYFDSDIIEDIA
ECCCCCCCCCCHHHCCCEEEECCCCCCCCCCCEEEECCCCCEEEEEEECCCCHHHHHHHH
SQTLSAIDNSE
HHHHHHHCCCC
>Mature Secondary Structure 
SRYVCKWKLIYTFFIFIVFNNCPLAFASPSLTKQLHTILKDNLADSLTPGAVLLISSPD
CCCEEHHHHHHHHHHHHHHCCCCCEECCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCC
LGTISVAAGLADKENDISMNITDSFRLASMSKTFLAVTVLKLVADKQLNLDDHIADLLPD
CCEEEEEECCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCC
SIDIERIPNGDEVTVQQLLQMRSGIPNYTDYDSYSDLIDTMADKEWTPEECIKLVYDKKP
CCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCC
DFKPGTAYEYSNTNYLLLQLIIENLTGESYAESIKKYILKPIRLKNTYIEKQEFDDDHHY
CCCCCCCEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHEHHHHHCCCCCCE
LSTHGYTLEDGKVVDVTDYDDGFGLADGGIISTAEDINIFIQALLKDKILLSPNYLTMML
EECCCEEECCCEEEEEECCCCCCCCCCCCEECCHHHHHHHHHHHHHCCEEECCCEEEEEE
TFPDDYGFGIGREEINGEMAWSHNGASSGYQGQYYYFPDRQLTVVILTNYFDSDIIEDIA
ECCCCCCCCCCHHHCCCEEEECCCCCCCCCCCEEEECCCCCEEEEEEECCCCHHHHHHHH
SQTLSAIDNSE
HHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3830154; 7925404; 3030739; 2175384; 2386365; 3997832; 7490745 [H]