Click here to switch to the map view.

The map label for this gene is tdk [H]

Identifier: 54293620

GI number: 54293620

Start: 728879

End: 729508

Strand: Direct

Name: tdk [H]

Synonym: lpl0673

Alternate gene names: 54293620

Gene position: 728879-729508 (Clockwise)

Preceding gene: 54293619

Following gene: 54293621

Centisome position: 21.79

GC content: 39.68

Gene sequence:

>630_bases
ATGGCAAAATTATATTTCTACTATGCCGCTATGAATGCAGGTAAAAGTACGGTGTTACTGCAGTCTAGCTATAATTACAG
AGAGCGAGGTATGCAAACTCTGTTATTTACCCCAGCTATCGATACACGTTACCAATATGGAACTATCTGTTCGCGAATCG
GTTTATCTGAGCAGGCTTATGCGTTTAACAACACGGATAATCTCTATGTTTTGACTCAAGAATTGCAACTACAAGCTACA
AAATACTCTTGTGTCCTGATTGACGAGGCTCAATTTTTAACTCGAGAGCAAGTGTATCAATTAACGGAAATAACCGATCA
AATGTCTATCCCAGTCCTAGCTTATGGGTTGCGCACTGACTTTAGAGGCGAGTTATTTCCCGGAAGTCAATTTTTACTGG
CATGGGCAGATGAGTTAATCGAATTAAAGACAATTTGTCATTGTGGCCGTAAAGCAACTATGAATATGAGAATTGATGAA
AATGGGCAAGCTGTTGTTGAGGGTGAGCAGGTATTGATAGGCGGCAATGAATCCTATGTTGCTACCTGTCGGTTGCATTA
TAAACGCGGTGAAGCAGGGAAGACCTTTCCAGGAAATAAATTGTTCAATAAAGATACCAATACTTTTTAA

Upstream 100 bases:

>100_bases
CTTGATATTGTTTTATTCACCTGTGCTGAGTTGTTGAGCAGTGGTTTCTAATTCCATCTCATAGTAAAGTAAAGCAAACG
AAGCTCAAAATAATAAATAC

Downstream 100 bases:

>100_bases
ATTTTGATATAATTTGCCGCAGTTTTTAGGCCTTAAATAAAGGAGAGGTGGTGTCGCATTCTGTCGCAGTGGAGTCGAAA
ACTTTTGTTCCCCGTGGTGA

Product: thymidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 209; Mature: 208

Protein sequence:

>209_residues
MAKLYFYYAAMNAGKSTVLLQSSYNYRERGMQTLLFTPAIDTRYQYGTICSRIGLSEQAYAFNNTDNLYVLTQELQLQAT
KYSCVLIDEAQFLTREQVYQLTEITDQMSIPVLAYGLRTDFRGELFPGSQFLLAWADELIELKTICHCGRKATMNMRIDE
NGQAVVEGEQVLIGGNESYVATCRLHYKRGEAGKTFPGNKLFNKDTNTF

Sequences:

>Translated_209_residues
MAKLYFYYAAMNAGKSTVLLQSSYNYRERGMQTLLFTPAIDTRYQYGTICSRIGLSEQAYAFNNTDNLYVLTQELQLQAT
KYSCVLIDEAQFLTREQVYQLTEITDQMSIPVLAYGLRTDFRGELFPGSQFLLAWADELIELKTICHCGRKATMNMRIDE
NGQAVVEGEQVLIGGNESYVATCRLHYKRGEAGKTFPGNKLFNKDTNTF
>Mature_208_residues
AKLYFYYAAMNAGKSTVLLQSSYNYRERGMQTLLFTPAIDTRYQYGTICSRIGLSEQAYAFNNTDNLYVLTQELQLQATK
YSCVLIDEAQFLTREQVYQLTEITDQMSIPVLAYGLRTDFRGELFPGSQFLLAWADELIELKTICHCGRKATMNMRIDEN
GQAVVEGEQVLIGGNESYVATCRLHYKRGEAGKTFPGNKLFNKDTNTF

Specific function: Phosphorylates Both Thymidine And Deoxyuridine. [C]

COG id: COG1435

COG function: function code F; Thymidine kinase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thymidine kinase family [H]

Homologues:

Organism=Escherichia coli, GI1787490, Length=189, Percent_Identity=63.4920634920635, Blast_Score=252, Evalue=2e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001267
- InterPro:   IPR020633
- InterPro:   IPR020634 [H]

Pfam domain/function: PF00265 TK [H]

EC number: =2.7.1.21 [H]

Molecular weight: Translated: 23798; Mature: 23667

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: PS00603 TK_CELLULAR_TYPE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKLYFYYAAMNAGKSTVLLQSSYNYRERGMQTLLFTPAIDTRYQYGTICSRIGLSEQAY
CCEEEEEEEEECCCCEEEEEECCCCHHHCCCEEEEEECCCCCCCCHHHHHHHCCCCCCEE
AFNNTDNLYVLTQELQLQATKYSCVLIDEAQFLTREQVYQLTEITDQMSIPVLAYGLRTD
EECCCCCEEEEEEEEEEEEEEEEEEEECCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCC
FRGELFPGSQFLLAWADELIELKTICHCGRKATMNMRIDENGQAVVEGEQVLIGGNESYV
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEEECCEEEEECCCCEE
ATCRLHYKRGEAGKTFPGNKLFNKDTNTF
EEEEEEEEECCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AKLYFYYAAMNAGKSTVLLQSSYNYRERGMQTLLFTPAIDTRYQYGTICSRIGLSEQAY
CEEEEEEEEECCCCEEEEEECCCCHHHCCCEEEEEECCCCCCCCHHHHHHHCCCCCCEE
AFNNTDNLYVLTQELQLQATKYSCVLIDEAQFLTREQVYQLTEITDQMSIPVLAYGLRTD
EECCCCCEEEEEEEEEEEEEEEEEEEECCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCC
FRGELFPGSQFLLAWADELIELKTICHCGRKATMNMRIDENGQAVVEGEQVLIGGNESYV
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEEECCEEEEECCCCEE
ATCRLHYKRGEAGKTFPGNKLFNKDTNTF
EEEEEEEEECCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA